Home Amines 34915-68-9
34915-68-9,MFCD00864680
Catalog No.:AA00C960

34915-68-9 | 2-(3-(tert-Butylamino)-2-hydroxypropoxy)benzonitrile

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50mg
95%
3 weeks  
$279.00   $195.00
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100mg
95%
3 weeks  
$358.00   $250.00
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250mg
95%
3 weeks  
$463.00   $324.00
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500mg
95%
3 weeks  
$665.00   $465.00
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1g
95%
3 weeks  
$820.00   $574.00
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2.5g
95%
3 weeks  
$1,574.00   $1,102.00
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5g
95%
3 weeks  
$2,970.00   $2,079.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C960
Chemical Name:
2-(3-(tert-Butylamino)-2-hydroxypropoxy)benzonitrile
CAS Number:
34915-68-9
Molecular Formula:
C14H20N2O2
Molecular Weight:
248.3208
MDL Number:
MFCD00864680
SMILES:
N#Cc1ccccc1OCC(CNC(C)(C)C)O
Properties
Computed Properties
 
Complexity:
290  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
1  
XLogP3:
1.9  

Literature

Title: Functional characterization of a first avian cytochrome P450 of the CYP2D subfamily (CYP2D49).

Journal: PloS one 20120101

Title: Impact of solvent conditions on separation and detection of basic drugs by micro liquid chromatography-mass spectrometry under overloading conditions.

Journal: Journal of chromatography. A 20110603

Title: Evaluating pharmacokinetic and pharmacodynamic interactions with computational models in supporting cumulative risk assessment.

Journal: International journal of environmental research and public health 20110501

Title: Extrapolating in vitro metabolic interactions to isolated perfused liver: predictions of metabolic interactions between R-bufuralol, bunitrolol, and debrisoquine.

Journal: Journal of pharmaceutical sciences 20101001

Title: CYP2D-related metabolism in animals of the Canoidea superfamily - species differences.

Journal: Veterinary research communications 20060701

Title: Roles of phenylalanine at position 120 and glutamic acid at position 222 in the oxidation of chiral substrates by cytochrome P450 2D6.

Journal: Chirality 20060201

Title: MetaSite: understanding metabolism in human cytochromes from the perspective of the chemist.

Journal: Journal of medicinal chemistry 20051103

Title: [Toxicologic analysis of some adrenergic-beta blockers in the diagnosis of intoxications].

Journal: Archiwum medycyny sadowej i kryminologii 20030101

Title: Functional evaluation of cytochrome P450 2D6 with Gly42Arg substitution expressed in Saccharomyces cerevisiae.

Journal: Pharmacogenetics 20011101

Title: Inactivation of rat cytochrome P450 2D enzyme by a further metabolite of 4-hydroxypropranolol, the major and active metabolite of propranolol.

Journal: Biological & pharmaceutical bulletin 20010901

Title: Plasma catecholamines, plasma renin activity and haemodynamics during sodium nitroprusside-induced hypotension and additional beta-blockage with bunitrolol.

Journal: European journal of clinical pharmacology 19810101

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