Home Other Building Blocks 348622-88-8
348622-88-8,MFCD19690945
Catalog No.:AA00C9LB

348622-88-8 | Uk 383367

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$46.00   $32.00
- +
5mg
≥98%
in stock  
$90.00   $63.00
- +
10mg
≥98%
in stock  
$125.00   $87.00
- +
25mg
≥98%
in stock  
$246.00   $172.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C9LB
Chemical Name:
Uk 383367
CAS Number:
348622-88-8
Molecular Formula:
C15H24N4O4
Molecular Weight:
324.3755
MDL Number:
MFCD19690945
SMILES:
ONC(=O)C[C@H](c1onc(n1)C(=O)N)CCCC1CCCCC1
Properties
Properties
 
Form:
Solid  
MP:
136-138℃  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
401  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
8  
XLogP3:
2.4  

Literature

Title: Hydroxamates: relationships between structure and plasma stability.

Journal: Journal of medicinal chemistry 20091112

Title: Potent and selective nonpeptidic inhibitors of procollagen C-proteinase.

Journal: Journal of medicinal chemistry 20070726

Title: Pharmacokinetics and metabolism of UK-383,367 in rats and dogs: a rationale for long-lived plasma radioactivity.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20060501

Title: Allan GA, Gedge JI, Nedderman AN, Roffey SJ, Small HF, Webster R.Pharmacokinetics and metabolism of UK-383,367 in rats and dogs: a rationale for long-lived plasma radioactivity.Xenobiotica. 2006 May;36(5):399-418.

Title: Bailey et al (2008) Succinyl hydroxamates as potent and selective non-peptidic inhibitors of procollagen C-proteinase: design, synthesis, and evaluation as topically applied, dermal anti-scarring agents. Bioorg.Med.Chem.Lett. 18 6562.

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