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345630-40-2,MFCD06411448
Catalog No.:AA00C9Y1

345630-40-2 | SF1670(PTENinhibitor)

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$45.00   $32.00
- +
5mg
98%
in stock  
$111.00   $78.00
- +
10mg
98%
in stock  
$144.00   $101.00
- +
25mg
98%
in stock  
$188.00   $132.00
- +
50mg
98%
in stock  
$245.00   $171.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C9Y1
Chemical Name:
SF1670(PTENinhibitor)
CAS Number:
345630-40-2
Molecular Formula:
C19H17NO3
Molecular Weight:
307.3432
MDL Number:
MFCD06411448
SMILES:
O=C1C(=O)c2cc(ccc2c2c1cccc2)NC(=O)C(C)(C)C
Properties
Computed Properties
 
Complexity:
519  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
3.1  

Literature

Title: Lateral compartmentalization of T cell receptor versus CD45 by galectin-N-glycan binding and microfilaments coordinate basal and activation signaling.

Journal: The Journal of biological chemistry 20071130

Title: Potent reversible inhibitors of the protein tyrosine phosphatase CD45.

Journal: Journal of medicinal chemistry 20010524

Title: Li Y, et al. Pretreatment with phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor SF1670augments the efficacy of granulocyte transfusion in a clinically relevant mouse model. Blood. 2011 Jun 16;117(24):6702-13.

Title: Montales MT, et al. Metformin and soybean-derived bioactive molecules attenuate the expansion of stem cell-like epithelial subpopulation and confer apoptotic sensitivity in human colon cancer cells. Genes Nutr. 2015 Nov;10(6):49.

Title: Amarjot Kaur Grewal, et al. Neuroprotective effect of pharmacological postconditioning on cerebral ischaemia-reperfusion-induced injury in mice. J Pharm Pharmacol. 2019 Jun;71(6):956-970.

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