4299-70-1,MFCD08144704
Catalog No.:AA00CAGP

4299-70-1 | L-Tryptophan methyl ester

Pack Size
Purity
Availability
Price(USD)
Quantity
  
50mg
Reagent Grade
in stock  
$457.00   $320.00
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  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
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Technical Information
Catalog Number:
AA00CAGP
Chemical Name:
L-Tryptophan methyl ester
CAS Number:
4299-70-1
Molecular Formula:
C12H14N2O2
Molecular Weight:
218.2518
MDL Number:
MFCD08144704
SMILES:
COC(=O)[C@H](Cc1c[nH]c2c1cccc2)N
Properties
Computed Properties
 
Complexity:
257  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
XLogP3:
1.5  

Literature

Title: Indoleamine 2,3-dioxygenase (IDO) induced by Leishmania infection of human dendritic cells.

Journal: Parasite immunology 20121001

Title: Indoleamine 2,3-dioxygenase expression and functional activity in dendritic cells exposed to cholera toxin.

Journal: Scandinavian journal of immunology 20120801

Title: Can diffusion tensor imaging (DTI) identify epileptogenic tubers in tuberous sclerosis complex? Correlation with α-[11C]methyl-L-tryptophan ([11C] AMT) positron emission tomography (PET).

Journal: Journal of child neurology 20120501

Title: Novel Cβ-Cγ bond cleavages of tryptophan-containing peptide radical cations.

Journal: Journal of the American Society for Mass Spectrometry 20120201

Title: Chiral calix[4]arenes bearing amino alcohol functionality as membrane carriers for transport of chiral amino acid methylesters and mandelic acid.

Journal: Chirality 20120201

Title: Expression of Stat3 and indoleamine 2, 3-dioxygenase in cornea keratocytes as factor of ocular immune privilege.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20120101

Title: A New-Age for Biologic Therapies: Long-Term Drug-Free Therapy with BiP?

Journal: Frontiers in immunology 20120101

Title: Conjugates of ferrocene with biological compounds. Coordination to gold complexes and antitumoral properties.

Journal: Journal of inorganic biochemistry 20111101

Title: Characterization of the kynurenine pathway in NSC-34 cell line: implications for amyotrophic lateral sclerosis.

Journal: Journal of neurochemistry 20110901

Title: Acyl substrate preferences of an IAA-amido synthetase account for variations in grape (Vitis vinifera L.) berry ripening caused by different auxinic compounds indicating the importance of auxin conjugation in plant development.

Journal: Journal of experimental botany 20110801

Title: Dichotomous effects of IFN-γ on dendritic cell function determine the extent of IL-12-driven antitumor T cell immunity.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20110701

Title: Human plasmacytoid dendritic cells induce CD8⁺ LAG-3⁺ Foxp3⁺ CTLA-4⁺ regulatory T cells that suppress allo-reactive memory T cells.

Journal: European journal of immunology 20110601

Title: Expression of indoleamine 2,3-dioxygenase in acute myeloid leukemia and the effect of its inhibition on cultured leukemia blast cells.

Journal: Medical oncology (Northwood, London, England) 20110301

Title: β-Elemene piperazine derivatives induce apoptosis in human leukemia cells through downregulation of c-FLIP and generation of ROS.

Journal: PloS one 20110101

Title: Interferon-γ regulates the proliferation and differentiation of mesenchymal stem cells via activation of indoleamine 2,3 dioxygenase (IDO).

Journal: PloS one 20110101

Title: Vascular endothelial expression of indoleamine 2,3-dioxygenase 1 forms a positive gradient towards the feto-maternal interface.

Journal: PloS one 20110101

Title: Crinum latifolium leave extracts suppress immune activation cascades in peripheral blood mononuclear cells and proliferation of prostate tumor cells.

Journal: Scientia pharmaceutica 20110101

Title: HIV-1 Tat activates indoleamine 2,3 dioxygenase in murine organotypic hippocampal slice cultures in a p38 mitogen-activated protein kinase-dependent manner.

Journal: Journal of neuroinflammation 20110101

Title: Antioxidant activity of unexplored indole derivatives: synthesis and screening.

Journal: European journal of medicinal chemistry 20101101

Title: Inhibitor of indoleamine-2,3-dioxygenase 1-methyl-D-tryptophan can stimulate the growth of immunogenic tumors.

Journal: Bulletin of experimental biology and medicine 20101001

Title: 1-L-methyltryptophan is a more effective inhibitor of vertebrate IDO2 enzymes than 1-D-methyltryptophan.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20100901

Title: Synthesis and antileishmanial activity of piperoyl-amino acid conjugates.

Journal: European journal of medicinal chemistry 20100801

Title: Biochemical characteristics and inhibitor selectivity of mouse indoleamine 2,3-dioxygenase-2.

Journal: Amino acids 20100701

Title: Synthesis, cytotoxicity and antileishmanial activity of some N-(2-(indol-3-yl)ethyl)-7-chloroquinolin-4-amines.

Journal: Chemical biology & drug design 20100601

Title: Evaluation of the enantioseparation capability of the novel chiral selector clindamycin phosphate towards basic drugs by micellar electrokinetic chromatography.

Journal: Journal of chromatography. A 20100312

Title: Relation of serum serotonin levels to bone density and structural parameters in women.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20100201

Title: A kinetic study of the photodynamic effect on tryptophan methyl ester and tryptophan octyl ester in DOPC vesicles.

Journal: Photochemistry and photobiology 20100101

Title: Central role of IFNgamma-indoleamine 2,3-dioxygenase axis in regulation of interleukin-12-mediated antitumor immunity.

Journal: Cancer research 20100101

Title: The role of indoleamine 2,3-dioxygenase in retinal pigment epithelial cell-mediated immune modulation.

Journal: Ocular immunology and inflammation 20100101

Title: Immunosuppressive properties of human umbilical cord-derived mesenchymal stem cells: role of B7-H1 and IDO.

Journal: Immunology and cell biology 20100101

Title: Epilepsy: The future scenario.

Journal: Annals of Indian Academy of Neurology 20100101

Title: Central administration of lipopolysaccharide induces depressive-like behavior in vivo and activates brain indoleamine 2,3 dioxygenase in murine organotypic hippocampal slice cultures.

Journal: Journal of neuroinflammation 20100101

Title: Oren-gedoku-to and its constituents with therapeutic potential in Alzheimer's disease inhibit indoleamine 2, 3-dioxygenase activity in vitro.

Journal: Journal of Alzheimer's disease : JAD 20100101

Title: Fractalkine receptor (CX3CR1) deficiency sensitizes mice to the behavioral changes induced by lipopolysaccharide.

Journal: Journal of neuroinflammation 20100101

Title: Kynurenine Pathway Metabolism is Involved in the Maintenance of the Intracellular NAD Concentration in Human Primary Astrocytes.

Journal: International journal of tryptophan research : IJTR 20100101

Title: Comment on 'Reduced cytotoxic function of effector CD8+ T cells is responsible for indoleamine 2,3-dioxygenase-dependent immune suppression'.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20091115

Title: Bis- and tris(pyridyl)amine-oxidovanadium complexes: characteristics and insulin-mimetic potential.

Journal: Dalton transactions (Cambridge, England : 2003) 20091014

Title: Binding immunoglobulin protein-treated peripheral blood monocyte-derived dendritic cells are refractory to maturation and induce regulatory T-cell development.

Journal: Immunology 20091001

Title: Granulocyte colony-stimulating factor-induced immature myeloid cells inhibit acute graft-versus-host disease lethality through an indoleamine dioxygenase-independent mechanism.

Journal: Immunology 20090901

Title: A straightforward total synthesis of (-)-chaetominine.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20090810

Title: Indoleamine 2,3-dioxygenase as a new target for malignant glioma therapy. Laboratory investigation.

Journal: Journal of neurosurgery 20090801

Title: 99mTc-DTPA-amino acids conjugate as specific SPECT pharmaceuticals for tumor imaging.

Journal: Chemical biology & drug design 20090801

Title: Investigation of enantiomeric separation of basic drugs by capillary electrophoresis using clindamycin phosphate as a novel chiral selector.

Journal: Electrophoresis 20090801

Title: (S)-Methyl 2-[(3R,4R)-2-benzyl-3-(2-fur-yl)-1-oxo-1,2,3,4-tetra-hydro-isoquinoline-4-carboxamido]-3-(1H-indol-3-yl)propanoate.

Journal: Acta crystallographica. Section E, Structure reports online 20090701

Title: The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20090615

Title: Prevention of spontaneous tumor development in a ret transgenic mouse model by ret peptide vaccination with indoleamine 2,3-dioxygenase inhibitor 1-methyl tryptophan.

Journal: Cancer research 20090501

Title: Photosensitizing properties of triplet beta-lapachones in acetonitrile solution.

Journal: Photochemistry and photobiology 20090101

Title: Regulatory T-cells and immune tolerance in pregnancy: a new target for infertility treatment?

Journal: Human reproduction update 20090101

Title: Imaging correlates of differential expression of indoleamine 2,3-dioxygenase in human brain tumors.

Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20090101

Title: Function of the tryptophan metabolite, L-kynurenine, in human corneal endothelial cells.

Journal: Molecular vision 20090101

Title: Mesenchymal stem cells can induce long-term acceptance of solid organ allografts in synergy with low-dose mycophenolate.

Journal: Transplant immunology 20081101

Title: Regioselective nitration of N(alpha),N(1)-bis(trifluoroacetyl)-L-tryptophan methyl ester: efficient synthesis of 2-nitro and 6-nitro-N-trifluoroacetyl-L-tryptophan methyl ester.

Journal: Bioorganic & medicinal chemistry letters 20081101

Title: The preference of tryptophan for membrane interfaces: insights from N-methylation of tryptophans in gramicidin channels.

Journal: The Journal of biological chemistry 20080808

Title: Functionalized magnetonanoparticles for MRI diagnosis and localization in epilepsy.

Journal: Epilepsia 20080801

Title: Enantiospecific synthesis of (+)-alstonisine via a stereospecific osmylation process.

Journal: Journal of natural products 20080801

Title: Indoleamine 2,3-dioxygenase expression promotes renal ischemia-reperfusion injury.

Journal: American journal of physiology. Renal physiology 20080701

Title: Methyl 3-(2-chlorophenyl)-2-(1H-indol-3-ylmethyl)-5-[1-(4-methoxyphenyl)-4-oxo-3-phenylazetidin-2-yl]-4-nitropyr-rolidine-2-carboxylate.

Journal: Acta crystallographica. Section E, Structure reports online 20080601

Title: Methyl 3-(4-bromo-phen-yl)-2-(1H-indol-3-ylmeth-yl)-5-[1-(4-methoxy-phen-yl)-4-oxo-2-phenyl-azetidin-2-yl]-4-nitro-pyrrolidine-2-carboxyl-ate.

Journal: Acta crystallographica. Section E, Structure reports online 20080601

Title: Sumatriptan normalizes the migraine attack-related increase in brain serotonin synthesis.

Journal: Neurology 20080205

Title: Mouse model for allogeneic immune reaction against fetus recapitulates human pre-eclampsia.

Journal: The journal of obstetrics and gynaecology research 20080201

Title: cis-(9S,10S)-Methyl 1-propyl-1,2,3,4-tetra-hydro-β-carboline-3-carboxyl-ate.

Journal: Acta crystallographica. Section E, Structure reports online 20080201

Title: Toxicology and pharmacokinetics of 1-methyl-d-tryptophan: absence of toxicity due to saturating absorption.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080101

Title: Indoleamine 2,3-dioxygenase-expressing dendritic cells are involved in the generation of CD4+CD25+ regulatory T cells in Peyer's patches in an orally tolerized, collagen-induced arthritis mouse model.

Journal: Arthritis research & therapy 20080101

Title: Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia.

Journal: Journal of neuroinflammation 20080101

Title: HIV-induced type I interferon and tryptophan catabolism drive T cell dysfunction despite phenotypic activation.

Journal: PloS one 20080101

Title: Microwave-Assisted Syntheses of Amino Acid Ester Substituted Benzoic Acid Amides: Potential Inhibitors of Human CD81-Receptor HCV-E2 Interaction.

Journal: The open medicinal chemistry journal 20080101

Title: Abnormal brain tryptophan metabolism and clinical correlates in Tourette syndrome.

Journal: Movement disorders : official journal of the Movement Disorder Society 20071115

Title: Tumor immune escape mediated by indoleamine 2,3-dioxygenase.

Journal: Immunology letters 20070815

Title: Brain regional alpha-[11C]methyl-L-tryptophan trapping, used as an index of 5-HT synthesis, in healthy adults: absence of an age effect.

Journal: European journal of nuclear medicine and molecular imaging 20070801

Title: Malaria parasite induces tryptophan-related immune suppression in mice.

Journal: Parasitology 20070701

Title: Indoleamine 2, 3-dioxygenase expression in cells of human acute monocyte leukemia (M(5)) and acute lymphocyte leukemia and therapeutic effect of its inhibitor 1-methyl tryptophan.

Journal: Zhongguo shi yan xue ye xue za zhi 20070601

Title: HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells.

Journal: Blood 20070415

Title: Modulation of tryptophan catabolism by human leukemic cells results in the conversion of CD25- into CD25+ T regulatory cells.

Journal: Blood 20070401

Title: Methylglyoxal-derived beta-carbolines formed from tryptophan and its derivates in the Maillard reaction.

Journal: Amino acids 20070201

Title: Enantiomeric impurity determination in capillary electrophoresis using a highly-sulfated cyclodextrins-based method.

Journal: Biomedical chromatography : BMC 20060801

Title: Determination of enantiomeric composition of samples by multivariate regression modeling of spectral data obtained with cyclodextrin guest-host complexes-Effect of an achiral surfactant and use of mixed cyclodextrins.

Journal: Talanta 20060227

Title: Role of chemical structure in molecular recognition by transferrin.

Journal: Journal of molecular recognition : JMR 20060101

Title: The kinetics of oxidation of GSH by protein radicals.

Journal: The Biochemical journal 20051215

Title: Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis.

Journal: Blood 20051001

Title: A quinonoid is an intermediate of oxidative deamination reaction catalyzed by Dopa decarboxylase.

Journal: FEBS letters 20050926

Title: Enantioselective capillary electrophoretic separation of tryptophane- and tyrosine-methylesters in a dual system with a tetra-oxadiaza-crown-ether derivative and a cyclodextrin.

Journal: Journal of pharmaceutical and biomedical analysis 20050715

Title: A crucial role for tryptophan catabolism at the host/Candida albicans interface.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20050301

Title: Determination of the enantiomeric composition of some molecules of pharmaceutical interest by chemometric analysis of the UV spectra of guest-host complexes formed with modified cyclodextrins.

Journal: Talanta 20050227

Title: Enhanced ligand affinity for receptors in which components of the binding site are independently mobile.

Journal: Chemistry & biology 20050101

Title: A method for quantitating the intracellular metabolism of AZT amino acid phosphoramidate pronucleotides by capillary high-performance liquid chromatography-electrospray ionization mass spectrometry.

Journal: Molecular pharmaceutics 20050101

Title: Model synthesis of nucleoside boranophosphoramidate with amino acid for prodrug purpose.

Journal: Nucleosides, nucleotides & nucleic acids 20050101

Title: Indoleamine 2,3-dioxygenase: distribution and function in the developing human placenta.

Journal: Journal of reproductive immunology 20040401

Title: Evaluation with alpha-[11C]methyl-L-tryptophan positron emission tomography for reoperation after failed epilepsy surgery.

Journal: Epilepsia 20040201

Title: The triplet-state lifetime of indole derivatives in aqueous solution.

Journal: Photochemistry and photobiology 20040101

Title: A synthesis of chiral 1,1,3-trisubstituted 1,2,3,4-tetrahydro-beta-carbolines by the Pictet-Spengler reaction of tryptophan and ketones: conversion of (1R,3S)-diastereomers into their (1S,3S)-counterparts by scission of the C(1)-N(2) bond.

Journal: Chemical & pharmaceutical bulletin 20031201

Title: 'Mix and shake' method for configurational assignment by NMR: application to chiral amines and alcohols.

Journal: Organic letters 20030821

Title: Highly efficient Lewis acid-catalysed Pictet-Spengler reactions discovered by parallel screening.

Journal: Chemical communications (Cambridge, England) 20030407

Title: Determination of ppb levels of tryptophan derivatives by capillary electrophoresis with homogeneous liquid-liquid extraction and sweeping method.

Journal: Chemical & pharmaceutical bulletin 20030401

Title: Does serotonin have trophic effects in temporal lobe epilepsy?

Journal: Neurology 20030311

Title: Quantification of the predominant monomeric catechins in baking chocolate standard reference material by LC/APCI-MS.

Journal: Journal of agricultural and food chemistry 20030129

Title: Influence of ion pairing on topical delivery of retinoic acid from microemulsions.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20030117

Title: Continuous ethanol administration influences rat brain 5-hyroxytrytamine synthesis non-umiformly: alpha-[14C]methyl-L-trytophan autoradiographic measurements.

Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20030101

Title: Inhibition of indoleamine 2,3-dioxygenase suppresses NK cell activity and accelerates tumor growth.

Journal: Journal of experimental therapeutics & oncology 20030101

Title: Tryptophan pyrrole ring cleavage enzymes in placenta.

Journal: Advances in experimental medicine and biology 20030101

Title: Stereospecific, enantiospecific total synthesis of the sarpagine indole alkaloids (E)16-epiaffinisine, (E)16-epinormacusine B, and dehydro-16-epiaffinisine.

Journal: Organic letters 20021226

Title: Enantiospecific, stereospecific total synthesis of the oxindole alkaloid alstonisine.

Journal: Organic letters 20021128

Title: Indoleamine 2,3-dioxygenase contributes to tumor cell evasion of T cell-mediated rejection.

Journal: International journal of cancer 20020910

Title: A short synthetic route to (+)-austamide, (+)-deoxyisoaustamide, and (+)-hydratoaustamide from a common precursor by a novel palladium-mediated indole --> dihydroindoloazocine cyclization.

Journal: Journal of the American Chemical Society 20020710

Title: Binding affinities of commonly employed sensitizers of viral inactivation.

Journal: Photochemistry and photobiology 20020601

Title: HeLa cells cocultured with peripheral blood lymphocytes acquire an immuno-inhibitory phenotype through up-regulation of indoleamine 2,3-dioxygenase activity.

Journal: Immunology 20020401

Title: Mapping of stereoselective recognition sites on human serum transferrin by capillary electrophoresis and molecular modelling.

Journal: Electrophoresis 20020301

Title: Total synthesis of isoroquefortine C.

Journal: The Journal of organic chemistry 20020208

Title: The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location.

Journal: Genomics 20020101

Title: General approach for the synthesis of sarpagine/macroline indole alkaloids. Enantiospecific total synthesis of the indole alkaloid trinervine.

Journal: Organic letters 20011213

Title: Reduction in serotonin synthesis following acute and chronic treatments with paroxetine, a selective serotonin reuptake inhibitor, in rat brain: an autoradiographic study with alpha-[14C]methyl-L-tryptophan(2).

Journal: Biochemical pharmacology 20011201

Title: Autism in tuberous sclerosis complex is related to both cortical and subcortical dysfunction.

Journal: Neurology 20011009

Title: Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.

Journal: The Journal of biological chemistry 20010518

Title: Characterization of the FAD-containing N-methyltryptophan oxidase from Escherichia coli.

Journal: Biochemistry 20010206

Title: N-methyltryptophan oxidase from Escherichia coli: reaction kinetics with N-methyl amino acid and carbinolamine substrates.

Journal: Biochemistry 20010206

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SDS
Tags:4299-70-1 Molecular Formula|4299-70-1 MDL|4299-70-1 SMILES|4299-70-1 L-Tryptophan methyl ester
Catalog No.: AA00CAGP
4299-70-1,MFCD08144704
4299-70-1 | L-Tryptophan methyl ester
Pack Size: 50mg
Purity: Reagent Grade
in stock
$457.00 $320.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00CAGP
Chemical Name: L-Tryptophan methyl ester
CAS Number: 4299-70-1
Molecular Formula: C12H14N2O2
Molecular Weight: 218.2518
MDL Number: MFCD08144704
SMILES: COC(=O)[C@H](Cc1c[nH]c2c1cccc2)N
Properties
Complexity: 257  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 1  
Heavy Atom Count: 16  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 2  
Rotatable Bond Count: 4  
XLogP3: 1.5  
Literature fold

Title: Indoleamine 2,3-dioxygenase (IDO) induced by Leishmania infection of human dendritic cells.

Journal: Parasite immunology20121001

Title: Indoleamine 2,3-dioxygenase expression and functional activity in dendritic cells exposed to cholera toxin.

Journal: Scandinavian journal of immunology20120801

Title: Can diffusion tensor imaging (DTI) identify epileptogenic tubers in tuberous sclerosis complex? Correlation with α-[11C]methyl-L-tryptophan ([11C] AMT) positron emission tomography (PET).

Journal: Journal of child neurology20120501

Title: Novel Cβ-Cγ bond cleavages of tryptophan-containing peptide radical cations.

Journal: Journal of the American Society for Mass Spectrometry20120201

Title: Chiral calix[4]arenes bearing amino alcohol functionality as membrane carriers for transport of chiral amino acid methylesters and mandelic acid.

Journal: Chirality20120201

Title: Expression of Stat3 and indoleamine 2, 3-dioxygenase in cornea keratocytes as factor of ocular immune privilege.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie20120101

Title: A New-Age for Biologic Therapies: Long-Term Drug-Free Therapy with BiP?

Journal: Frontiers in immunology20120101

Title: Conjugates of ferrocene with biological compounds. Coordination to gold complexes and antitumoral properties.

Journal: Journal of inorganic biochemistry20111101

Title: Characterization of the kynurenine pathway in NSC-34 cell line: implications for amyotrophic lateral sclerosis.

Journal: Journal of neurochemistry20110901

Title: Acyl substrate preferences of an IAA-amido synthetase account for variations in grape (Vitis vinifera L.) berry ripening caused by different auxinic compounds indicating the importance of auxin conjugation in plant development.

Journal: Journal of experimental botany20110801

Title: Dichotomous effects of IFN-γ on dendritic cell function determine the extent of IL-12-driven antitumor T cell immunity.

Journal: Journal of immunology (Baltimore, Md. : 1950)20110701

Title: Human plasmacytoid dendritic cells induce CD8⁺ LAG-3⁺ Foxp3⁺ CTLA-4⁺ regulatory T cells that suppress allo-reactive memory T cells.

Journal: European journal of immunology20110601

Title: Expression of indoleamine 2,3-dioxygenase in acute myeloid leukemia and the effect of its inhibition on cultured leukemia blast cells.

Journal: Medical oncology (Northwood, London, England)20110301

Title: β-Elemene piperazine derivatives induce apoptosis in human leukemia cells through downregulation of c-FLIP and generation of ROS.

Journal: PloS one20110101

Title: Interferon-γ regulates the proliferation and differentiation of mesenchymal stem cells via activation of indoleamine 2,3 dioxygenase (IDO).

Journal: PloS one20110101

Title: Vascular endothelial expression of indoleamine 2,3-dioxygenase 1 forms a positive gradient towards the feto-maternal interface.

Journal: PloS one20110101

Title: Crinum latifolium leave extracts suppress immune activation cascades in peripheral blood mononuclear cells and proliferation of prostate tumor cells.

Journal: Scientia pharmaceutica20110101

Title: HIV-1 Tat activates indoleamine 2,3 dioxygenase in murine organotypic hippocampal slice cultures in a p38 mitogen-activated protein kinase-dependent manner.

Journal: Journal of neuroinflammation20110101

Title: Antioxidant activity of unexplored indole derivatives: synthesis and screening.

Journal: European journal of medicinal chemistry20101101

Title: Inhibitor of indoleamine-2,3-dioxygenase 1-methyl-D-tryptophan can stimulate the growth of immunogenic tumors.

Journal: Bulletin of experimental biology and medicine20101001

Title: 1-L-methyltryptophan is a more effective inhibitor of vertebrate IDO2 enzymes than 1-D-methyltryptophan.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology20100901

Title: Synthesis and antileishmanial activity of piperoyl-amino acid conjugates.

Journal: European journal of medicinal chemistry20100801

Title: Biochemical characteristics and inhibitor selectivity of mouse indoleamine 2,3-dioxygenase-2.

Journal: Amino acids20100701

Title: Synthesis, cytotoxicity and antileishmanial activity of some N-(2-(indol-3-yl)ethyl)-7-chloroquinolin-4-amines.

Journal: Chemical biology & drug design20100601

Title: Evaluation of the enantioseparation capability of the novel chiral selector clindamycin phosphate towards basic drugs by micellar electrokinetic chromatography.

Journal: Journal of chromatography. A20100312

Title: Relation of serum serotonin levels to bone density and structural parameters in women.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research20100201

Title: A kinetic study of the photodynamic effect on tryptophan methyl ester and tryptophan octyl ester in DOPC vesicles.

Journal: Photochemistry and photobiology20100101

Title: Central role of IFNgamma-indoleamine 2,3-dioxygenase axis in regulation of interleukin-12-mediated antitumor immunity.

Journal: Cancer research20100101

Title: The role of indoleamine 2,3-dioxygenase in retinal pigment epithelial cell-mediated immune modulation.

Journal: Ocular immunology and inflammation20100101

Title: Immunosuppressive properties of human umbilical cord-derived mesenchymal stem cells: role of B7-H1 and IDO.

Journal: Immunology and cell biology20100101

Title: Epilepsy: The future scenario.

Journal: Annals of Indian Academy of Neurology20100101

Title: Central administration of lipopolysaccharide induces depressive-like behavior in vivo and activates brain indoleamine 2,3 dioxygenase in murine organotypic hippocampal slice cultures.

Journal: Journal of neuroinflammation20100101

Title: Oren-gedoku-to and its constituents with therapeutic potential in Alzheimer's disease inhibit indoleamine 2, 3-dioxygenase activity in vitro.

Journal: Journal of Alzheimer's disease : JAD20100101

Title: Fractalkine receptor (CX3CR1) deficiency sensitizes mice to the behavioral changes induced by lipopolysaccharide.

Journal: Journal of neuroinflammation20100101

Title: Kynurenine Pathway Metabolism is Involved in the Maintenance of the Intracellular NAD Concentration in Human Primary Astrocytes.

Journal: International journal of tryptophan research : IJTR20100101

Title: Comment on 'Reduced cytotoxic function of effector CD8+ T cells is responsible for indoleamine 2,3-dioxygenase-dependent immune suppression'.

Journal: Journal of immunology (Baltimore, Md. : 1950)20091115

Title: Bis- and tris(pyridyl)amine-oxidovanadium complexes: characteristics and insulin-mimetic potential.

Journal: Dalton transactions (Cambridge, England : 2003)20091014

Title: Binding immunoglobulin protein-treated peripheral blood monocyte-derived dendritic cells are refractory to maturation and induce regulatory T-cell development.

Journal: Immunology20091001

Title: Granulocyte colony-stimulating factor-induced immature myeloid cells inhibit acute graft-versus-host disease lethality through an indoleamine dioxygenase-independent mechanism.

Journal: Immunology20090901

Title: A straightforward total synthesis of (-)-chaetominine.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20090810

Title: Indoleamine 2,3-dioxygenase as a new target for malignant glioma therapy. Laboratory investigation.

Journal: Journal of neurosurgery20090801

Title: 99mTc-DTPA-amino acids conjugate as specific SPECT pharmaceuticals for tumor imaging.

Journal: Chemical biology & drug design20090801

Title: Investigation of enantiomeric separation of basic drugs by capillary electrophoresis using clindamycin phosphate as a novel chiral selector.

Journal: Electrophoresis20090801

Title: (S)-Methyl 2-[(3R,4R)-2-benzyl-3-(2-fur-yl)-1-oxo-1,2,3,4-tetra-hydro-isoquinoline-4-carboxamido]-3-(1H-indol-3-yl)propanoate.

Journal: Acta crystallographica. Section E, Structure reports online20090701

Title: The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity.

Journal: Journal of immunology (Baltimore, Md. : 1950)20090615

Title: Prevention of spontaneous tumor development in a ret transgenic mouse model by ret peptide vaccination with indoleamine 2,3-dioxygenase inhibitor 1-methyl tryptophan.

Journal: Cancer research20090501

Title: Photosensitizing properties of triplet beta-lapachones in acetonitrile solution.

Journal: Photochemistry and photobiology20090101

Title: Regulatory T-cells and immune tolerance in pregnancy: a new target for infertility treatment?

Journal: Human reproduction update20090101

Title: Imaging correlates of differential expression of indoleamine 2,3-dioxygenase in human brain tumors.

Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging20090101

Title: Function of the tryptophan metabolite, L-kynurenine, in human corneal endothelial cells.

Journal: Molecular vision20090101

Title: Mesenchymal stem cells can induce long-term acceptance of solid organ allografts in synergy with low-dose mycophenolate.

Journal: Transplant immunology20081101

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Title: Tumor immune escape mediated by indoleamine 2,3-dioxygenase.

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Journal: Alcohol and alcoholism (Oxford, Oxfordshire)20030101

Title: Inhibition of indoleamine 2,3-dioxygenase suppresses NK cell activity and accelerates tumor growth.

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Title: Tryptophan pyrrole ring cleavage enzymes in placenta.

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