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Home Nitro Compounds 22246-45-3
22246-45-3,MFCD00985061
Catalog No.:AA00CBQ9

22246-45-3 | 7-Nitro-1,3,4,5-tetrahydro-benzo[b]azepin-2-one

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
95%
in stock  
$118.00   $83.00
- +
1g
95%
in stock  
$261.00   $183.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00CBQ9
Chemical Name:
7-Nitro-1,3,4,5-tetrahydro-benzo[b]azepin-2-one
CAS Number:
22246-45-3
Molecular Formula:
C10H10N2O3
Molecular Weight:
206.1980
MDL Number:
MFCD00985061
SMILES:
O=C1CCCc2c(N1)ccc(c2)[N+](=O)[O-]
NSC Number:
611258
Properties
Computed Properties
 
Complexity:
274  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
XLogP3:
1.3  

Downstream Synthesis Route

[1]CurrentPatentAssignee:HANSOHPHARMACEUTICALGROUPCOLTD-CN106349233,2017,ALocationinpatent:Paragraph0295;0302;0303;0304;0305

[2]Locationinpatent:experimentalpartTomasi,Sophie;Renault,Jacques;Martin,Bénédicte;Duhieu,Stephane;Cerec,Virginie;LeRoch,Myriam;Uriac,Philippe;Delcros,Jean-Guy[JournalofMedicinalChemistry,2010,vol.53,#21,p.7647-7663]

[3]CurrentPatentAssignee:HANSOHPHARMACEUTICALGROUPCOLTD-CN106349241,2017,ALocationinpatent:Paragraph0369;0370;0371;0372

[4]CurrentPatentAssignee:NEURAXON,INC.-US2008/234237,2008,A1Locationinpatent:Page/Pagecolumn56

[5]CurrentPatentAssignee:LIGANDPHARMACEUTICALSINC;TEVAPHARMACEUTICALINDUSTRIESLTD.-WO2008/51547,2008,A1Locationinpatent:Page/Pagecolumn258;302-303

[6]Weinberg,LindaR.;Albom,MarkS.;Angeles,ThelmaS.;Husten,Jean;Lisko,JosephG.;McHugh,RobertJ.;Milkiewicz,KarenL.;Murthy,Seetha;Ott,GregoryR.;Theroff,JayP.;Tripathy,Rabindranath;Underiner,TedL.;Zificsak,CraigA.;Dorsey,BruceD.[BioorganicandMedicinalChemistryLetters,2011,vol.21,#1,p.164-167]

[7]Buege,Axel;Locke,Christian;Koehler,Thomas;Nuhn,Peter[ArchivderPharmazie,1994,vol.327,#2,p.99-104]

[8]CurrentPatentAssignee:PFIZERINC-WO2004/69245,2004,A1Locationinpatent:Page/Pagecolumn95,105

[9]CurrentPatentAssignee:SANOFI-US2013/261106,2013,A1Locationinpatent:Paragraph0556

[10]CurrentPatentAssignee:SANOFI-WO2013/150036,2013,A1Locationinpatent:Page/Pagecolumn107;108

[11]CurrentPatentAssignee:SHANGHAIZHIMENGPHARMACEUTICALTECH;SHANGHAIZHIMENGBIOPHARMA-EP3978478,2022,A1

[12]CurrentPatentAssignee:SHANGHAIZHIMENGPHARMACEUTICALTECH;SHANGHAIZHIMENGBIOPHARMA-EP3978478,2022,A1Locationinpatent:Paragraph0083-0085

[13]CurrentPatentAssignee:SHANGHAIZHIMENGPHARMACEUTICALTECH;SHANGHAIZHIMENGBIOPHARMA-EP3978478,2022,A1Locationinpatent:Paragraph0083-0085

[1]Osadchii,S.A.;Kochubei,N.V.[RussianJournalofAppliedChemistry,1994,vol.67,#11.2,p.1674-1676][ZhurnalPrikladnoiKhimii(Sankt-Peterburg,RussianFederation),1994,vol.67,#11,p.1909-1911]

[2]CurrentPatentAssignee:HANSOHPHARMACEUTICALGROUPCOLTD-CN106349241,2017,ALocationinpatent:Paragraph0369;0373;0374;0375

[3]CurrentPatentAssignee:HANSOHPHARMACEUTICALGROUPCOLTD-CN106349233,2017,ALocationinpatent:Paragraph0295;0306;0307;0308

[4]CurrentPatentAssignee:PFIZERINC-WO2004/69245,2004,A1Locationinpatent:Page/Pagecolumn95-96

[5]Buege,Axel;Locke,Christian;Koehler,Thomas;Nuhn,Peter[ArchivderPharmazie,1994,vol.327,#2,p.99-104]

[6]Locationinpatent:schemeortableWeinberg,LindaR.;Albom,MarkS.;Angeles,ThelmaS.;Husten,Jean;Lisko,JosephG.;McHugh,RobertJ.;Milkiewicz,KarenL.;Murthy,Seetha;Ott,GregoryR.;Theroff,JayP.;Tripathy,Rabindranath;Underiner,TedL.;Zificsak,CraigA.;Dorsey,BruceD.[BioorganicandMedicinalChemistryLetters,2011,vol.21,#1,p.164-167]

[7]CurrentPatentAssignee:SHANGHAIZHIMENGBIOPHARMA-EP3978478,2022,A1

[8]CurrentPatentAssignee:SHANGHAIZHIMENGBIOPHARMA-EP3978478,2022,A1Locationinpatent:Paragraph0083;0086-0087

[9]CurrentPatentAssignee:SHANGHAIZHIMENGBIOPHARMA-EP3978478,2022,A1Locationinpatent:Paragraph0083;0086-0087

4424-80-0    22246-45-3   
9-nitro-1,3,4,5-tetrahydro-benzo<i>b</i>azepin-2-one 
 
7,9-dinitro-1,3,4,5-tetrahydro-benzo<i>b</i>azepin-2-one 

[1]Johnson,PaulD.;Aristoff,PaulA.;Zurenko,GaryE.;Schaadt,RondaD.;Yagi,BettyH.;Ford,CharlesW.;Hamel,JudithC.;Stapert,Douglas;Moerman,JudyK.[BioorganicandMedicinalChemistryLetters,2003,vol.13,#23,p.4197-4200]

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Tags:22246-45-3 Molecular Formula|22246-45-3 MDL|22246-45-3 SMILES|22246-45-3 7-Nitro-1,3,4,5-tetrahydro-benzo[b]azepin-2-one