+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Carboxes 31772-42-6
31772-42-6,MFCD00464874
Catalog No.:AA00CLL1

31772-42-6 | 2-Chloro-1-(5-methyl-thiophen-2-yl)-ethanone

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
95%
in stock  
$120.00   $84.00
- +
250mg
95%
in stock  
$228.00   $160.00
- +
1g
95%
in stock  
$544.00   $381.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00CLL1
Chemical Name:
2-Chloro-1-(5-methyl-thiophen-2-yl)-ethanone
CAS Number:
31772-42-6
Molecular Formula:
C7H7ClOS
Molecular Weight:
174.6479
MDL Number:
MFCD00464874
SMILES:
Cc1ccc(s1)C(=O)CCl
Properties
Computed Properties
 
Complexity:
138  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
2.6  

Downstream Synthesis Route
31772-42-6    2253-73-8    109-77-3   
4-amino-5-(5-methylthiophene-2-carbonyl)-2-(propan-2-yl)aminothiophene-3-carbonitrile 

[1]Boutard,Nicolas;Sabiniarz,Aleksandra;Czerwińska,Klaudia;Jarosz,Małgorzata;Cierpich,Anna;Kolasińska,Ewa;Wiklik,Katarzyna;Gluza,Karolina;Commandeur,Claude;Buda,Anna;Stasiowska,Agata;Bobowska,Aneta;Galek,Mariusz;Fabritius,Charles-Henry;Bugaj,Marta;Palacz,Edyta;Mazan,Andrzej;Zarębski,Adrian;Krawczyńska,Karolina;Żurawska,Małgorzata;Zawadzki,Przemysław;Milik,Mariusz;Węgrzyn,Paulina;Dobrzańska,Monika;Brzózka,Krzysztof;Kowalczyk,Piotr[BioorganicandMedicinalChemistryLetters,2019,vol.29,#4,p.607-613]

Literature

Title: Thienylhalomethylketones: Irreversible glycogen synthase kinase 3 inhibitors as useful pharmacological tools.

Journal: Bioorganic & medicinal chemistry 20091001

Title: Thienyl and phenyl alpha-halomethyl ketones: new inhibitors of glycogen synthase kinase (GSK-3beta) from a library of compound searching.

Journal: Journal of medicinal chemistry 20031023

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 31772-42-6
29683-77-0

29683-77-0

 50460-05-4

50460-05-4

 72612-03-4

72612-03-4
Building Blocks
More >
Tags:31772-42-6 Molecular Formula|31772-42-6 MDL|31772-42-6 SMILES|31772-42-6 2-Chloro-1-(5-methyl-thiophen-2-yl)-ethanone