Home Amines 366-79-0
366-79-0,MFCD00462263
Catalog No.:AA00CW5G

366-79-0 | (4-Fluoro-benzoylamino)-acetic acid

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1mg
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1 week  
$299.00   $209.00
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5mg
>95%
1 week  
$319.00   $223.00
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10mg
>95%
1 week  
$358.00   $250.00
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500mg
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1g
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$591.00   $414.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00CW5G
Chemical Name:
(4-Fluoro-benzoylamino)-acetic acid
CAS Number:
366-79-0
Molecular Formula:
C9H8FNO3
Molecular Weight:
197.1631
MDL Number:
MFCD00462263
SMILES:
O=C(c1ccc(cc1)F)NCC(=O)O
Properties
Properties
 
Form:
Solid  
MP:
173℃  

Computed Properties
 
Complexity:
224  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
-0.1  

Downstream Synthesis Route

[1]Obermeier;Niebch;Thiemer[Arzneimittel-Forschung/DrugResearch,1985,vol.35,#1,p.60-67]

[1]Obermeier;Niebch;Thiemer[Arzneimittel-Forschung/DrugResearch,1985,vol.35,#1,p.60-67]

[2]Hlavica;Niebch[Arzneimittel-Forschung/DrugResearch,1985,vol.35,#1,p.67-74]

[1]Pharmazie,2000,vol.55,p.825-828

2936-62-1    366-79-0   
rac-4-fluoro-N-(phenyl-o-tolylmethyl)carbamoylmethyl}benzamide 

[1]BioorganicandMedicinalChemistryLetters,2008,vol.18,p.5533-5536

55095-20-0    366-79-0   
rac-4-fluoro-N-(phenyl-m-tolylmethyl)carbamoylmethyl}benzamide 

[1]Locationinpatent:schemeortableJolidon,Synese;Alberati,Daniela;Dowle,Adam;Fischer,Holger;Hainzl,Dominik;Narquizian,Robert;Norcross,Roger;Pinard,Emmanuel[BioorganicandMedicinalChemistryLetters,2008,vol.18,#20,p.5533-5536]

Literature

Title: Renogram comparison of p-[(18)F]fluorohippurate with o-[(125)I]iodohippurate and [(99m)Tc]MAG3 in normal rats.

Journal: Nuclear medicine communications 20111001

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Identification of human metabolites of (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a novel If channel inhibitor, and investigation of the transporter-mediated renal and hepatic excretion of these metabolites.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090801

Title: Identification and simultaneous determination of p-FHA and p-FBA, two metabolites of anti-tumor agent--Fluorapacin in rat urine.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090515

Title: Investigation of the in vitro metabolism of the analgesic flupirtine.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090301

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SDS
Tags:366-79-0 Molecular Formula|366-79-0 MDL|366-79-0 SMILES|366-79-0 (4-Fluoro-benzoylamino)-acetic acid