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351986-85-1,MFCD00321410
Catalog No.:AA00CYSE

351986-85-1 | 3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$32.00   $22.00
- +
5mg
98%
in stock  
$76.00   $54.00
- +
10mg
98%
in stock  
$113.00   $79.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00CYSE
Chemical Name:
3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone
CAS Number:
351986-85-1
Molecular Formula:
C26H24IN7O
Molecular Weight:
577.4195
MDL Number:
MFCD00321410
SMILES:
Ic1cccc(c1)/C=N/Nc1nc(nc(n1)N(c1ccccc1)c1ccccc1)N1CCOCC1
Properties
Properties
 
Form:
Solid  

Computed Properties
 
Complexity:
634  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  
XLogP3:
6.2  

Literature

Title: Vesicle trafficking plays a novel role in erythroblast enucleation.

Journal: Blood 20101028

Title: Triggering role of acid sphingomyelinase in endothelial lysosome-membrane fusion and dysfunction in coronary arteries.

Journal: American journal of physiology. Heart and circulatory physiology 20100301

Title: Vacuolin-1-modulated exocytosis and cell resealing in mast cells.

Journal: Cellular signalling 20090801

Title: HPMA based macromolecular therapeutics: internalization, intracellular pathway and cell death depend on the character of covalent bond between the drug and the peptidic spacer and also on spacer composition.

Journal: Journal of drug targeting 20060701

Title: The small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing.

Journal: EMBO reports 20040901

Title: Jan Cerny, et al.The small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing. EMBO Rep. 2004 Sep;5(9):883-8.

Title: Osamu Sano, et al. Vacuolin-1 inhibits autophagy by impairing lysosomal maturation via PIKfyve inhibition. FEBS Lett. 2016 Jun;590(11):1576-85.

Title: Yingying Lu, et al. Vacuolin-1 potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A. Autophagy

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SDS
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Tags:351986-85-1 Molecular Formula|351986-85-1 MDL|351986-85-1 SMILES|351986-85-1 3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone
Catalog No.: AA00CYSE
351986-85-1,MFCD00321410
351986-85-1 | 3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone
Pack Size： 1mg
Purity： 98%
in stock
$32.00 $22.00
Pack Size： 5mg
Purity： 98%
in stock
$76.00 $54.00
Pack Size： 10mg
Purity： 98%
in stock
$113.00 $79.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA00CYSE
Chemical Name: 3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone
CAS Number: 351986-85-1
Molecular Formula: C26H24IN7O
Molecular Weight: 577.4195
MDL Number: MFCD00321410
SMILES: Ic1cccc(c1)/C=N/Nc1nc(nc(n1)N(c1ccccc1)c1ccccc1)N1CCOCC1
Properties
Form: Solid  
Complexity: 634  
Covalently-Bonded Unit Count: 1  
Defined Bond Stereocenter Count: 1  
Heavy Atom Count: 35  
Hydrogen Bond Acceptor Count: 8  
Hydrogen Bond Donor Count: 1  
Rotatable Bond Count: 7  
XLogP3: 6.2  
Literature fold

Title: Vesicle trafficking plays a novel role in erythroblast enucleation.

Journal: Blood20101028

Title: Triggering role of acid sphingomyelinase in endothelial lysosome-membrane fusion and dysfunction in coronary arteries.

Journal: American journal of physiology. Heart and circulatory physiology20100301

Title: Vacuolin-1-modulated exocytosis and cell resealing in mast cells.

Journal: Cellular signalling20090801

Title: HPMA based macromolecular therapeutics: internalization, intracellular pathway and cell death depend on the character of covalent bond between the drug and the peptidic spacer and also on spacer composition.

Journal: Journal of drug targeting20060701

Title: The small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing.

Journal: EMBO reports20040901

Title: Jan Cerny, et al.The small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing. EMBO Rep. 2004 Sep;5(9):883-8.

Title: Osamu Sano, et al. Vacuolin-1 inhibits autophagy by impairing lysosomal maturation via PIKfyve inhibition. FEBS Lett. 2016 Jun;590(11):1576-85.

Title: Yingying Lu, et al. Vacuolin-1 potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A. Autophagy

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