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Home Other Building Blocks 373356-48-0
373356-48-0,MFCD00728969
Catalog No.:AA00D5G4

373356-48-0 | 4-(Piperazin-1-yl)thieno[2,3-d]pyrimidine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
>95%
1 week  
$281.00   $197.00
- +
5mg
>95%
1 week  
$297.00   $208.00
- +
10mg
>95%
1 week  
$327.00   $229.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00D5G4
Chemical Name:
4-(Piperazin-1-yl)thieno[2,3-d]pyrimidine
CAS Number:
373356-48-0
Molecular Formula:
C10H12N4S
Molecular Weight:
220.2941
MDL Number:
MFCD00728969
SMILES:
N1CCN(CC1)c1ncnc2c1ccs2
Properties
Computed Properties
 
Complexity:
220  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
0.9  

Downstream Synthesis Route

[1]CurrentPatentAssignee:ASTRAZENECAPLC-US2003/225097,2003,A1Locationinpatent:Page34,44

373356-48-0   
3-((2,3-dihydro-1H-indan-2-yl)(propyl)amino)propylmethanesulfonate 
 
N-propyl-N-(3-(4-(thiophene2,3-dpyrimidin-4-yl)piperazin-1-yl)propyl)-2,3-dihydro-1H-indan-2-amine 

[1]CurrentPatentAssignee:CHANGZHOUUNIVERSITY-CN113979915,2022,ALocationinpatent:Paragraph0194;0201

Literature

Title: Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia.

Journal: Nature chemical biology 20120129

Title: Synthesis, immunosuppressive activity and structure-activity relationship study of a new series of 4-N-piperazinyl-thieno[2,3-d]pyrimidine analogues.

Journal: Bioorganic & medicinal chemistry letters 20100201

Title: Design and synthesis of orally-active and selective azaindane 5HT2c agonist for the treatment of obesity.

Journal: Bioorganic & medicinal chemistry letters 20100101

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SDS
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Tags:373356-48-0 Molecular Formula|373356-48-0 MDL|373356-48-0 SMILES|373356-48-0 4-(Piperazin-1-yl)thieno[2,3-d]pyrimidine