Title: Cyclic GMP-mediated memory enhancement in the object recognition test by inhibitors of phosphodiesterase-2 in mice.
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Title: Inhibition of phosphodiesterase 2 augments cGMP and cAMP signaling to ameliorate pulmonary hypertension.
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Title: Phosphodiesterase 2A localized in the spinal cord contributes to inflammatory pain processing.
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Title: X-ray crystal structure of phosphodiesterase 2 in complex with a highly selective, nanomolar inhibitor reveals a binding-induced pocket important for selectivity.
Journal: Journal of the American Chemical Society 20130814
Title: Phosphodiesterase-2 inhibitor reverses corticosterone-induced neurotoxicity and related behavioural changes via cGMP/PKG dependent pathway.
Journal: The international journal of neuropsychopharmacology 20130501
Title: Phosphodiesterase 2 inhibitors promote axonal outgrowth in organotypic slice co-cultures.
Journal: Neuro-Signals 20130101
Title: Inhibition of phoshodiesterase type 2 or type 10 reverses object memory deficits induced by scopolamine or MK-801.
Journal: Behavioural brain research 20130101
Title: Pendrin protein abundance in the kidney is regulated by nitric oxide and cAMP.
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Title: Mechanisms of carbon monoxide attenuation of tubuloglomerular feedback.
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Title: PDE5A suppression of acute beta-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin I phosphorylation.
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Title: Anxiolytic effects of phosphodiesterase-2 inhibitors associated with increased cGMP signaling.
Journal: The Journal of pharmacology and experimental therapeutics 20091101
Title: A novel PDE2A reporter cell line: characterization of the cellular activity of PDE inhibitors.
Journal: Molecular pharmaceutics 20090101
Title: Phosphodiesterase 2 and 5 inhibition attenuates the object memory deficit induced by acute tryptophan depletion.
Journal: European journal of pharmacology 20081214
Title: ANP-mediated cGMP signaling and phosphodiesterase inhibition in the rat cervical spinal cord.
Journal: Journal of chemical neuroanatomy 20060601
Title: Inhibition of phosphodiesterase 2 increases neuronal cGMP, synaptic plasticity and memory performance.
Journal: Neuropharmacology 20041201
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