Home Aldehydes 53389-99-4
53389-99-4,MFCD00442935
Catalog No.:AA00D8JK

53389-99-4 | 2-(2-Chlorobenzyloxy)benzaldehyde

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  • Technical Information
  • Properties
  • Downstream Synthesis Route
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Technical Information
Catalog Number:
AA00D8JK
Chemical Name:
2-(2-Chlorobenzyloxy)benzaldehyde
CAS Number:
53389-99-4
Molecular Formula:
C14H11ClO2
Molecular Weight:
246.6889
MDL Number:
MFCD00442935
SMILES:
O=Cc1ccccc1OCc1ccccc1Cl
Properties
Computed Properties
 
Complexity:
244  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
4  
XLogP3:
3.5  

Downstream Synthesis Route
53389-99-4   
2-(2-chloro-benzyloxy)-benzaldehyde-thiosemicarbazone 

[1]Buu-Hoietal.[JournaloftheChemicalSociety,1956,p.713,714]

[1]Zhao,Shuangmei;Zhen,Yongqi;Fu,Leilei;Gao,Feng;Zhou,Xianli;Huang,Shuai;Zhang,Lan[BioorganicandMedicinalChemistryLetters,2019,vol.29,#19]

[2]Krasnov,KonstantinA.;Dorovatovskii,PavelV.;Zubavichus,YanV.;Timofeeva,TatianaV.;Khrustalev,VictorN.[Tetrahedron,2017,vol.73,#5,p.542-549]

[3]Buu-Hoietal.[JournaloftheChemicalSociety,1956,p.713,714]

[1]Hellwinkel;Goke[Synthesis,1995,#9,p.1135-1141]

[1]Yang,Pengfei;Xu,Weiyan;Wang,Rongchao;Zhang,Min;Xie,Chunsong;Zeng,Xiaofei;Wang,Min[OrganicLetters,2019,vol.21,#10,p.3658-3662]

[2]Hellwinkel;Goke[Synthesis,1995,#9,p.1135-1141]

[3]Li,Xiao;Zhang,Lun;Xu,Jing;Liu,Chenyu;Zhang,Xiaojian;Abdelmoneim,AmrAbbas;Zhang,Qian;Ke,Jiaqi;Zhang,Yingnan;Wang,Lei;Yang,Fan;Luo,Cheng;Jin,Jia;Ye,Fei[JournalofChemicalInformationandModeling,2022,vol.62,#3,p.692-702]

Literature

Title: Synthesis and anticancer activity of benzyloxybenzaldehyde derivatives against HL-60 cells.

Journal: Bioorganic & medicinal chemistry 20050301

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