Name: Name:ML213
Brand: AABLOCKS
SKU: AA00DA8L
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00DA8L

Chemical Name: ML213

CAS Number: 489402-47-3

Molecular Formula: C17H23NO

Molecular Weight: 257.3706

MDL Number: MFCD23136017

SMILES: O=C(C1CC2CC1CC2)Nc1c(C)cc(cc1C)C

Properties

Complexity: 341

Covalently-Bonded Unit Count: 1

Heavy Atom Count: 19

Hydrogen Bond Acceptor Count: 1

Hydrogen Bond Donor Count: 1

Rotatable Bond Count: 2

Undefined Atom Stereocenter Count: 3

XLogP3: 4.2

Literature fold

Title: Discovery, Synthesis, and Structure Activity Relationship of a Series of N-Aryl- bicyclo[2.2.1]heptane-2-carboxamides: Characterization of ML213 as a Novel KCNQ2 and KCNQ4 Potassium Channel Opener.

Journal: ACS chemical neuroscience20111019

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

Title: Brueggemann LI, et al. Differential activation of vascular smooth muscle Kv7.4, Kv7.5, and Kv7.4/7.5 channels by ML213 and ICA-069673. Mol Pharmacol. 2014 Sep;86(3):330-41.

Title: Jepps TA, et al. Vasorelaxant effects of novel Kv 7.4 channel enhancers ML213 and NS15370. Br J Pharmacol. 2014 Oct;171(19):4413-24.

Title: Yu H, et al. Discovery, Synthesis, and Structure Activity Relationship of a Series of N-Aryl- bicyclo.2.1heptane-2-carboxamides: Characterization of ML213 as a Novel KCNQ2 and KCNQ4 Potassium Channel Opener. ACS Chem Neurosci. 2011 Oct 19;2(10):572-577.

489402-47-3 | ML213