Name: Name:Lasmiditan
Brand: AABLOCKS
SKU: AA00DB3R
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00DB3R

Chemical Name: Lasmiditan

CAS Number: 439239-90-4

Molecular Formula: C19H18F3N3O2

Molecular Weight: 377.3603

MDL Number: MFCD18633238

SMILES: CN1CCC(CC1)C(=O)c1cccc(n1)NC(=O)c1c(F)cc(cc1F)F

Properties

Complexity: 530

Covalently-Bonded Unit Count: 1

Heavy Atom Count: 27

Hydrogen Bond Acceptor Count: 7

Hydrogen Bond Donor Count: 1

Rotatable Bond Count: 4

XLogP3: 2.8

Literature fold

Title: Emerging treatment for chronic migraine and refractory chronic migraine.

Journal: Expert opinion on emerging drugs20120901

Title: The 5-HT1F receptor agonist lasmiditan as a potential treatment of migraine attacks: a review of two placebo-controlled phase II trials.

Journal: The journal of headache and pain20120601

Title: Defining and refining 5-HT receptor targets for migraine.

Journal: The Lancet. Neurology20120501

Title: Efficacy and tolerability of lasmiditan, an oral 5-HT(1F) receptor agonist, for the acute treatment of migraine: a phase 2 randomised, placebo-controlled, parallel-group, dose-ranging study.

Journal: The Lancet. Neurology20120501

Title: Preclinical pharmacological profile of the selective 5-HT1F receptor agonist lasmiditan. A comment.

Journal: Cephalalgia : an international journal of headache20110701

Title: Treatment of migraine: update on new therapies.

Journal: Current opinion in neurology20110601

Title: Preclinical pharmacological profile of the selective 5-HT1F receptor agonist lasmiditan.

Journal: Cephalalgia : an international journal of headache20101001

Title: Acute treatment of migraine with the selective 5-HT1F receptor agonist lasmiditan--a randomised proof-of-concept trial.

Journal: Cephalalgia : an international journal of headache20101001

Title: Molecule of the month. Lasmiditan hydrochloride.

Journal: Drug news & perspectives20100901

439239-90-4 | Lasmiditan