555-55-5,MFCD22199534
Catalog No.:AA00DC08

555-55-5 | Hispidin

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$133.00   $93.00
- +
10mg
>98.0%(HPLC)
in stock  
$398.00   $279.00
- +
50mg
>98.0%(HPLC)
in stock  
$1,191.00   $834.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00DC08
Chemical Name:
Hispidin
CAS Number:
555-55-5
Molecular Formula:
C13H10O5
Molecular Weight:
246.2155
MDL Number:
MFCD22199534
SMILES:
Oc1oc(/C=C/c2ccc(c(c2)O)O)cc(=O)c1
Properties
Properties
 
Form:
Solid  
MP:
312-315℃  
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
421  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
1  
Formal Charge:
0  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
1.7  

Literature

Title: p66Shc signaling is involved in stress responses elicited by anthracycline treatment of rat cardiomyoblasts.

Journal: Archives of toxicology 20160701

Title: Hispidin analogue davallialactone attenuates carbon tetrachloride-induced hepatotoxicity in mice.

Journal: Journal of natural products 20121026

Title: Hispidin produced from Phellinus linteus protects against peroxynitrite-mediated DNA damage and hydroxyl radical generation.

Journal: Chemico-biological interactions 20120930

Title: First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G.

Journal: ACS chemical biology 20120316

Title: A pharmacologically-based array to identify targets of cyclosporine A-induced toxicity in cultured renal proximal tubule cells.

Journal: Toxicology and applied pharmacology 20120115

Title: Hispidin isolated from Phellinus linteus protects against hydrogen peroxide-induced oxidative stress in pancreatic MIN6N β-cells.

Journal: Journal of medicinal food 20111101

Title: Phenolic compounds with NF-κB inhibitory effects from the fungus Phellinus baumii.

Journal: Bioorganic & medicinal chemistry letters 20110601

Title: α-Glucosidase and aldose reductase inhibitory activities from the fruiting body of Phellinus merrillii.

Journal: Journal of agricultural and food chemistry 20110525

Title: PKC-β activation and pharmacologically induced weight gain during antipsychotic treatment.

Journal: Pharmacogenomics 20110401

Title: Phosphorylation of p66shc mediates 6-hydroxydopamine cytotoxicity.

Journal: Free radical research 20110301

Title: Antioxidant hispidin derivatives from medicinal mushroom Inonotus hispidus.

Journal: Chemical & pharmaceutical bulletin 20110101

Title: Inhibition of protein tyrosine phosphatase 1beta by hispidin derivatives isolated from the fruiting body of Phellinus linteus.

Journal: Natural product communications 20101201

Title: Styrylpyrones from the medicinal fungus Phellinus baumii and their antioxidant properties.

Journal: Bioorganic & medicinal chemistry letters 20100915

Title: Hispidin produced from Phellinus linteus protects pancreatic beta-cells from damage by hydrogen peroxide.

Journal: Archives of pharmacal research 20100601

Title: Oxidative stress response of Inonotus obliquus induced by hydrogen peroxide.

Journal: Medical mycology 20091201

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Isolation and characterization of a new hispolone derivative from antioxidant extracts of Pistacia atlantica.

Journal: Phytotherapy research : PTR 20090901

Title: PKCbetaII modulates translation independently from mTOR and through RACK1.

Journal: The Biochemical journal 20081001

Title: Peroxidase-mediated formation of the fungal polyphenol 3,14'-bihispidinyl.

Journal: Journal of microbiology and biotechnology 20080101

Title: Protein kinase C beta overexpression induces fibrotic effects in human proximal tubular epithelial cells.

Journal: The international journal of biochemistry & cell biology 20080101

Title: Inhibition of low-density lipoprotein oxidation and oxidative burst in polymorphonuclear neutrophils by caffeic acid and hispidin derivatives isolated from sword brake fern (Pteris ensiformis Burm.).

Journal: Journal of agricultural and food chemistry 20071226

Title: Highly oxygenated and unsaturated metabolites providing a diversity of hispidin class antioxidants in the medicinal mushrooms Inonotus and Phellinus.

Journal: Bioorganic & medicinal chemistry 20070515

Title: Matrix metalloproteinase-9 is differentially expressed in nonfunctioning invasive and noninvasive pituitary adenomas and increases invasion in human pituitary adenoma cell line.

Journal: The American journal of pathology 20070101

Title: Hispidin analogs from the mushroom Inonotus xeranticus and their free radical scavenging activity.

Journal: Bioorganic & medicinal chemistry letters 20060501

Title: Effect of protein kinase C inhibitors on porcine oocyte activation.

Journal: Journal of experimental zoology. Part A, Comparative experimental biology 20060401

Title: Regulation of skin microvasculature angiogenesis, cell migration, and permeability by a specific inhibitor of PKCalpha.

Journal: The Journal of investigative dermatology 20060201

Title: Hispidin derivatives from the mushroom Inonotus xeranticus and their antioxidant activity.

Journal: Journal of natural products 20060201

Title: Expression and modulation of an NADPH oxidase in mammalian astrocytes.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20051005

Title: IL-10 production induced by HIV-1 Tat stimulation of human monocytes is dependent on the activation of PKC beta(II) and delta isozymes.

Journal: Microbes and infection 20041101

Title: An antioxidant hispidin from the mycelial cultures of Phellinus linteus.

Journal: Archives of pharmacal research 20040601

Title: A beta-secretase (BACE1) inhibitor hispidin from the mycelial cultures of Phellinus linteus.

Journal: Planta medica 20040201

Title: Isolation, structure, and HIV-1-integrase inhibitory activity of structurally diverse fungal metabolites.

Journal: Journal of industrial microbiology & biotechnology 20031201

Title: Antiviral activity of Inonotus hispidus.

Journal: Fitoterapia 20030701

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Kim DE, et al. The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway. Exp Cell Res. 2014 Oct 1;327(2):264-75.

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Related Products of 555-55-5
Tags:555-55-5 Molecular Formula|555-55-5 MDL|555-55-5 SMILES|555-55-5 Hispidin
Catalog No.: AA00DC08
555-55-5,MFCD22199534
555-55-5 | Hispidin
Pack Size: 1mg
Purity: ≥95%
in stock
$133.00 $93.00
Pack Size: 10mg
Purity: >98.0%(HPLC)
in stock
$398.00 $279.00
Pack Size: 50mg
Purity: >98.0%(HPLC)
in stock
$1,191.00 $834.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00DC08
Chemical Name: Hispidin
CAS Number: 555-55-5
Molecular Formula: C13H10O5
Molecular Weight: 246.2155
MDL Number: MFCD22199534
SMILES: Oc1oc(/C=C/c2ccc(c(c2)O)O)cc(=O)c1
Properties
Form: Solid  
MP: 312-315℃  
Storage: -20 ℃;  
Complexity: 421  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 1  
Formal Charge: 0  
Heavy Atom Count: 18  
Hydrogen Bond Acceptor Count: 5  
Hydrogen Bond Donor Count: 3  
Isotope Atom Count: 0  
Rotatable Bond Count: 2  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 1.7  
Literature fold

Title: p66Shc signaling is involved in stress responses elicited by anthracycline treatment of rat cardiomyoblasts.

Journal: Archives of toxicology20160701

Title: Hispidin analogue davallialactone attenuates carbon tetrachloride-induced hepatotoxicity in mice.

Journal: Journal of natural products20121026

Title: Hispidin produced from Phellinus linteus protects against peroxynitrite-mediated DNA damage and hydroxyl radical generation.

Journal: Chemico-biological interactions20120930

Title: First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G.

Journal: ACS chemical biology20120316

Title: A pharmacologically-based array to identify targets of cyclosporine A-induced toxicity in cultured renal proximal tubule cells.

Journal: Toxicology and applied pharmacology20120115

Title: Hispidin isolated from Phellinus linteus protects against hydrogen peroxide-induced oxidative stress in pancreatic MIN6N β-cells.

Journal: Journal of medicinal food20111101

Title: Phenolic compounds with NF-κB inhibitory effects from the fungus Phellinus baumii.

Journal: Bioorganic & medicinal chemistry letters20110601

Title: α-Glucosidase and aldose reductase inhibitory activities from the fruiting body of Phellinus merrillii.

Journal: Journal of agricultural and food chemistry20110525

Title: PKC-β activation and pharmacologically induced weight gain during antipsychotic treatment.

Journal: Pharmacogenomics20110401

Title: Phosphorylation of p66shc mediates 6-hydroxydopamine cytotoxicity.

Journal: Free radical research20110301

Title: Antioxidant hispidin derivatives from medicinal mushroom Inonotus hispidus.

Journal: Chemical & pharmaceutical bulletin20110101

Title: Inhibition of protein tyrosine phosphatase 1beta by hispidin derivatives isolated from the fruiting body of Phellinus linteus.

Journal: Natural product communications20101201

Title: Styrylpyrones from the medicinal fungus Phellinus baumii and their antioxidant properties.

Journal: Bioorganic & medicinal chemistry letters20100915

Title: Hispidin produced from Phellinus linteus protects pancreatic beta-cells from damage by hydrogen peroxide.

Journal: Archives of pharmacal research20100601

Title: Oxidative stress response of Inonotus obliquus induced by hydrogen peroxide.

Journal: Medical mycology20091201

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology20091001

Title: Isolation and characterization of a new hispolone derivative from antioxidant extracts of Pistacia atlantica.

Journal: Phytotherapy research : PTR20090901

Title: PKCbetaII modulates translation independently from mTOR and through RACK1.

Journal: The Biochemical journal20081001

Title: Peroxidase-mediated formation of the fungal polyphenol 3,14'-bihispidinyl.

Journal: Journal of microbiology and biotechnology20080101

Title: Protein kinase C beta overexpression induces fibrotic effects in human proximal tubular epithelial cells.

Journal: The international journal of biochemistry & cell biology20080101

Title: Inhibition of low-density lipoprotein oxidation and oxidative burst in polymorphonuclear neutrophils by caffeic acid and hispidin derivatives isolated from sword brake fern (Pteris ensiformis Burm.).

Journal: Journal of agricultural and food chemistry20071226

Title: Highly oxygenated and unsaturated metabolites providing a diversity of hispidin class antioxidants in the medicinal mushrooms Inonotus and Phellinus.

Journal: Bioorganic & medicinal chemistry20070515

Title: Matrix metalloproteinase-9 is differentially expressed in nonfunctioning invasive and noninvasive pituitary adenomas and increases invasion in human pituitary adenoma cell line.

Journal: The American journal of pathology20070101

Title: Hispidin analogs from the mushroom Inonotus xeranticus and their free radical scavenging activity.

Journal: Bioorganic & medicinal chemistry letters20060501

Title: Effect of protein kinase C inhibitors on porcine oocyte activation.

Journal: Journal of experimental zoology. Part A, Comparative experimental biology20060401

Title: Regulation of skin microvasculature angiogenesis, cell migration, and permeability by a specific inhibitor of PKCalpha.

Journal: The Journal of investigative dermatology20060201

Title: Hispidin derivatives from the mushroom Inonotus xeranticus and their antioxidant activity.

Journal: Journal of natural products20060201

Title: Expression and modulation of an NADPH oxidase in mammalian astrocytes.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20051005

Title: IL-10 production induced by HIV-1 Tat stimulation of human monocytes is dependent on the activation of PKC beta(II) and delta isozymes.

Journal: Microbes and infection20041101

Title: An antioxidant hispidin from the mycelial cultures of Phellinus linteus.

Journal: Archives of pharmacal research20040601

Title: A beta-secretase (BACE1) inhibitor hispidin from the mycelial cultures of Phellinus linteus.

Journal: Planta medica20040201

Title: Isolation, structure, and HIV-1-integrase inhibitory activity of structurally diverse fungal metabolites.

Journal: Journal of industrial microbiology & biotechnology20031201

Title: Antiviral activity of Inonotus hispidus.

Journal: Fitoterapia20030701

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry20020419

Title: Kim DE, et al. The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway. Exp Cell Res. 2014 Oct 1;327(2):264-75.

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