Home Other Building Blocks 52807-12-2
52807-12-2,MFCD08063662
Catalog No.:AA00DDDQ

52807-12-2 | 4'-hydroxyflurbiprofen

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Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$116.00   $81.00
- +
5mg
≥95%
in stock  
$509.00   $356.00
- +
10mg
≥95%
in stock  
$903.00   $632.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DDDQ
Chemical Name:
4'-hydroxyflurbiprofen
CAS Number:
52807-12-2
Molecular Formula:
C15H13FO3
Molecular Weight:
260.2603
MDL Number:
MFCD08063662
SMILES:
OC(=O)C(c1ccc(c(c1)F)c1ccc(cc1)O)C
Properties
Computed Properties
 
Complexity:
313  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
1  
XLogP3:
3.8  

Literature

Title: Site of metabolism prediction on cytochrome P450 2C9: a knowledge-based docking approach.

Journal: Journal of computer-aided molecular design 20100501

Title: CYP2D6-CYP2C9 protein-protein interactions and isoform-selective effects on substrate binding and catalysis.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090801

Title: Synthesis and biological activity of flurbiprofen analogues as selective inhibitors of beta-amyloid(1)(-)(42) secretion.

Journal: Journal of medicinal chemistry 20050908

Title: Differences in flurbiprofen pharmacokinetics between CYP2C9*1/*1, *1/*2, and *1/*3 genotypes.

Journal: European journal of clinical pharmacology 20030401

Title: Minimal in vivo activation of CYP2C9-mediated flurbiprofen metabolism by dapsone.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20010801

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SDS
Tags:52807-12-2 Molecular Formula|52807-12-2 MDL|52807-12-2 SMILES|52807-12-2 4'-hydroxyflurbiprofen