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51093-55-1,MFCD00211182
Catalog No.:AA00DDE5

51093-55-1 | ROSEOFLAVIN

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1mg
≥95%
in stock  
$46.00   $32.00
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5mg
≥95%
in stock  
$79.00   $55.00
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10mg
≥95%
in stock  
$120.00   $84.00
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25mg
≥95%
in stock  
$252.00   $176.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DDE5
Chemical Name:
ROSEOFLAVIN
CAS Number:
51093-55-1
Molecular Formula:
C18H23N5O6
Molecular Weight:
405.4051
MDL Number:
MFCD00211182
SMILES:
OC[C@H]([C@H]([C@H](Cn1c2cc(N(C)C)c(cc2nc2c1nc(=O)[nH]c2=O)C)O)O)O
Properties
Properties
 
Form:
Solid  
MP:
276-278°C  
Storage:
-20 ℃;Light sensitive;  

Computed Properties
 
Complexity:
726  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
3  
XLogP3:
-1.7  

Literature

Title: Identification of the Key Enzyme of Roseoflavin Biosynthesis.

Journal: Angewandte Chemie (International ed. in English) 20160510

Title: The antibiotics roseoflavin and 8-demethyl-8-amino-riboflavin from Streptomyces davawensis are metabolized by human flavokinase and human FAD synthetase.

Journal: Biochemical pharmacology 20111215

Title: A novel N,N-8-amino-8-demethyl-D-riboflavin Dimethyltransferase (RosA) catalyzing the two terminal steps of roseoflavin biosynthesis in Streptomyces davawensis.

Journal: The Journal of biological chemistry 20111104

Title: The riboflavin analog roseoflavin targets an FMN-riboswitch and blocks Listeria monocytogenes growth, but also stimulates virulence gene-expression and infection.

Journal: RNA biology 20110101

Title: RibM from Streptomyces davawensis is a riboflavin/roseoflavin transporter and may be useful for the optimization of riboflavin production strains.

Journal: BMC biotechnology 20110101

Title: Photophysical characterisation and photo-cycle dynamics of LOV1-His domain of phototropin from Chlamydomonas reinhardtii with roseoflavin monophosphate cofactor.

Journal: Journal of photochemistry and photobiology. B, Biology 20101005

Title: Absorption and emission spectroscopic characterization of BLUF protein Slr1694 from Synechocystis sp. PCC6803 with roseoflavin cofactor.

Journal: Journal of photochemistry and photobiology. B, Biology 20091109

Title: In vivo generation of flavoproteins with modified cofactors.

Journal: Journal of molecular biology 20090206

Title: Roseoflavin is a natural antibacterial compound that binds to FMN riboswitches and regulates gene expression.

Journal: RNA biology 20090101

Title: The RFN riboswitch of Bacillus subtilis is a target for the antibiotic roseoflavin produced by Streptomyces davawensis.

Journal: RNA biology 20090101

Title: Model systems for flavoenzyme activity: an electrochemically tuneable model of roseoflavin.

Journal: Chemical communications (Cambridge, England) 20040507

Title: Lee ER, et al. Roseoflavin is a natural antibacterial compound that binds to FMN riboswitches and regulates gene expression. RNA Biol. 2009;6(2):187-194.

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SDS
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