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5053-08-7,MFCD00133315
Catalog No.:AA00DEG4

5053-08-7 | Fenspiride hydrochloride

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100mg
98%(HPLC)
in stock  
$54.00   $38.00
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5g
≥95%
in stock  
$80.00   $56.00
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10g
≥95%
in stock  
$139.00   $97.00
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25g
≥95%
in stock  
$309.00   $216.00
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50g
≥95%
in stock  
$460.00   $322.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DEG4
Chemical Name:
Fenspiride hydrochloride
CAS Number:
5053-08-7
Molecular Formula:
C15H21ClN2O2
Molecular Weight:
296.7924
MDL Number:
MFCD00133315
SMILES:
O=C1NCC2(O1)CCN(CC2)CCc1ccccc1.Cl
NSC Number:
757825
Properties
Computed Properties
 
Complexity:
318  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  

Literature

Title: Large-volume injection of sample diluents not miscible with the mobile phase as an alternative approach in sample preparation for bioanalysis: an application for fenspiride bioequivalence.

Journal: Bioanalysis 20110901

Title: [The use of eurespal for the treatment of chronic laryngitis].

Journal: Vestnik otorinolaringologii 20110101

Title: [The estimation of clinical efficacy of eurespal in the postoperative period following surgical intervention on paranasal sinuses].

Journal: Vestnik otorinolaringologii 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: [Experience in using erespal in the treatment of acute respiratory diseases in children in outpatient practice].

Journal: Vestnik otorinolaringologii 20100101

Title: [Pathogenetic correction of postoperative inflammation in modern rhinosurgery].

Journal: Vestnik otorinolaringologii 20100101

Title: [Efficiency of combination therapy for acute otitis media].

Journal: Vestnik otorinolaringologii 20100101

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: [Experience with fenspiride in a rhinosurgeon's practice].

Journal: Vestnik otorinolaringologii 20090101

Title: [Pathogenetic therapy for inflammatory diseases of the middle ear].

Journal: Vestnik otorinolaringologii 20090101

Title: [Clinicofunctional condition and quality of life in patients with chronic obstructive pulmonary disease before and after outpatient treatment with fenspiride].

Journal: Terapevticheskii arkhiv 20080101

Title: [Hearing rehabilitation in patients with acute otitis media treated with fenspiride].

Journal: Vestnik otorinolaringologii 20080101

Title: [The effectiveness of fenspiride in the treatment of patients with chronic obstructive pulmonary disease].

Journal: Klinicheskaia meditsina 20070101

Title: [New pharmaceuticals in treatment of chronic dust bronchitis].

Journal: Klinicheskaia meditsina 20070101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: [Erespal in combined therapy of acute rhinosinusitis].

Journal: Vestnik otorinolaringologii 20060101

Title: Comparison of fenspiride with beclomethasone as adjunctive anti-inflammatory treatment in patients with chronic obstructive pulmonary disease.

Journal: Clinical drug investigation 20060101

Title: [Anti-inflammatory therapy of paranasal sinuses diseases].

Journal: Vestnik otorinolaringologii 20060101

Title: [The effect of fenspiride on the number of exacerbations and the time of first exacerbation in patients with chronic bronchitis].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20050801

Title: [Fenspiride in patients with acute bronchitis].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20050701

Title: [Usefulness of fenspiride in the treatment of acute otitis media in children].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20050601

Title: [Effectiveness and tolerance of fenspiride treatment in chronic sinusitis. Results of the Polish multicenter study].

Journal: Otolaryngologia polska = The Polish otolaryngology 20050101

Title: [Potential of antiinflammatory therapy in patients with chronic obstructive lung disease].

Journal: Klinicheskaia meditsina 20050101

Title: [Acute intoxication with fenspiride].

Journal: Przeglad lekarski 20040101

Title: [Erespal effectiveness in exudative otitis media].

Journal: Vestnik otorinolaringologii 20030101

Title: [Fenspiride-a new alternative on the therapy of obstructive lung disease].

Journal: Pneumologia (Bucharest, Romania) 20030101

Title: [Bronchial inflammation during chronic bronchitis, importance of fenspiride].

Journal: Presse medicale (Paris, France : 1983) 20020901

Title: [ENT inflammation and importance of fenspiride].

Journal: Presse medicale (Paris, France : 1983) 20020901

Title: Detection of fenspiride and identification of in vivo metabolites in horse body fluids by capillary gas chromatography-mass spectrometry: administration, biotransformation and urinary excretion after a single oral dose.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020205

Title: [Experience in treating patients with chronic obstructive bronchitis with fenspirid].

Journal: Terapevticheskii arkhiv 20020101

Title: [Effectiveness of fenspiride in patients with chronic obstructive bronchitis].

Journal: Klinicheskaia meditsina 20010101

Title: Matuszewska A, et al. Long-term administration of fenspiride has no negative impact on bone mineral density and bone turnover in young growing rats. Adv Clin Exp Med. 2019 Jun;28(6):771-776.

Title: Cortijo J, et al. Effects of fenspiride on human bronchial cyclic nucleotide phosphodiesterase isoenzymes: functional and biochemical study. Eur J Pharmacol. 1998 Jan 2;341(1):79-86.

Title: De Castro CM, et al. Fenspiride: an anti-inflammatory drug with potential benefits in the treatment of endotoxemia. Eur J Pharmacol. 1995 Dec 29;294(2-3):669-76.

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