Home Other Building Blocks 440122-66-7
440122-66-7,MFCD16618385
Catalog No.:AA00DGPX

440122-66-7 | WAY200070

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$102.00   $72.00
- +
5mg
≥98%
in stock  
$103.00   $72.00
- +
10mg
≥98%
in stock  
$192.00   $134.00
- +
25mg
≥98%
in stock  
$430.00   $301.00
- +
50mg
≥98%
in stock  
$706.00   $494.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DGPX
Chemical Name:
WAY200070
CAS Number:
440122-66-7
Molecular Formula:
C13H8BrNO3
Molecular Weight:
306.1115
MDL Number:
MFCD16618385
SMILES:
Oc1ccc(cc1)c1oc2c(n1)cc(cc2Br)O
Properties
Computed Properties
 
Complexity:
296  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
3.4  

Literature

Title: Estrogen receptor β represses Akt signaling in breast cancer cells via downregulation of HER2/HER3 and upregulation of PTEN: implications for tamoxifen sensitivity.

Journal: Breast cancer research : BCR 20110101

Title: Differential effects of estrogen receptor alpha and beta specific agonists on social learning of food preferences in female mice.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080901

Title: WAY-200070, a selective agonist of estrogen receptor beta as a potential novel anxiolytic/antidepressant agent.

Journal: Neuropharmacology 20080601

Title: Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-beta ligands.

Journal: Journal of medicinal chemistry 20041007

Title: Hughes ZA, et al. WAY-200070, a selective agonist of estrogen receptor beta as a potential novel anxiolytic/antidepressant agent. Neuropharmacology. 2008 Jun;54(7):1136-42.

Title: Clipperton Allen AE, et al. Agonistic behavior in males and females: effects of an estrogen receptor beta agonist in gonadectomized and gonadally intact mice. Psychoneuroendocrinology. 2010 Aug;35(7):1008-22.

Title: Clipperton AE, et al. Differential effects of estrogen receptor alpha and beta specific agonists on social learning of food preferences in female mice. Neuropsychopharmacology. 2008 Sep;33(10):2362-75.

Title: Weiser MJ, et al. Estrogen receptor-beta agonist diarylpropionitrile: biological activities of R- and S-enantiomers on behavior and hormonal response to stress. Endocrinology. 2009 Apr;150(4):1817-25.

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SDS
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