Home Fluorides 442633-00-3
442633-00-3,MFCD03036271
Catalog No.:AA00DGPY

442633-00-3 | 2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide

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1mg
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5mg
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10mg
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250mg
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00DGPY
Chemical Name:
2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide
CAS Number:
442633-00-3
Molecular Formula:
C18H17FN2O
Molecular Weight:
296.3388
MDL Number:
MFCD03036271
SMILES:
O=C(c1ccccc1F)NCCc1c(C)[nH]c2c1cccc2
Properties
Computed Properties
 
Complexity:
389  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
XLogP3:
3.8  

Downstream Synthesis Route

[1]Baggett,AndrewW.;Cournia,Zoe;Han,MinSuk;Patargias,George;Glass,AdamC.;Liu,Shih-Yuan;Nolen,BradJ.[ChemMedChem,2012,vol.7,#7,p.1286-1294]

[1]Baggett,AndrewW.;Cournia,Zoe;Han,MinSuk;Patargias,George;Glass,AdamC.;Liu,Shih-Yuan;Nolen,BradJ.[ChemMedChem,2012,vol.7,#7,p.1286-1294]

[1]Baggett,AndrewW.;Cournia,Zoe;Han,MinSuk;Patargias,George;Glass,AdamC.;Liu,Shih-Yuan;Nolen,BradJ.[ChemMedChem,2012,vol.7,#7,p.1286-1294]

[1]Locationinpatent:experimentalpartBaggett,AndrewW.;Cournia,Zoe;Han,MinSuk;Patargias,George;Glass,AdamC.;Liu,Shih-Yuan;Nolen,BradJ.[ChemMedChem,2012,vol.7,#7,p.1286-1294]

[2]Fokin,ArtemI.;Chuprov-Netochin,RomanN.;Malyshev,AlexanderS.;Romero,Stéphane;Semenova,MarinaN.;Konyushkin,LeonidD.;Leonov,SergeyV.;Semenov,VictorV.;Gautreau,AlexisM.[FrontiersinPharmacology,2022,vol.13]

C11H12N2 
  442633-00-3 

[1]Baggett,AndrewW.;Cournia,Zoe;Han,MinSuk;Patargias,George;Glass,AdamC.;Liu,Shih-Yuan;Nolen,BradJ.[ChemMedChem,2012,vol.7,#7,p.1286-1294]

Literature

Title: Dynamic maintenance of asymmetric meiotic spindle position through Arp2/3-complex-driven cytoplasmic streaming in mouse oocytes.

Journal: Nature cell biology 20110828

Title: Arp2/3 complex regulates asymmetric division and cytokinesis in mouse oocytes.

Journal: PloS one 20110101

Title: Hetrick B, et al. Small molecules CK-666 and CK-869 inhibit actin-related protein 2/3 complex by blocking an activating conformational change. Chem Biol. 2013 May 23;20(5):701-12.

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SDS
Tags:442633-00-3 Molecular Formula|442633-00-3 MDL|442633-00-3 SMILES|442633-00-3 2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide