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4610-75-7,MFCD00631149
Catalog No.:AA00DICL

4610-75-7 | Ethyl 5-hydroxy-2-phenylbenzofuran-3-carboxylate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
96%
in stock  
$228.00   $160.00
- +
1g
96%
in stock  
$544.00   $381.00
- +
5g
96%
in stock  
$1,640.00   $1,148.00
- +
10g
96%
in stock  
$2,804.00   $1,963.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00DICL
Chemical Name:
Ethyl 5-hydroxy-2-phenylbenzofuran-3-carboxylate
CAS Number:
4610-75-7
Molecular Formula:
C17H14O4
Molecular Weight:
282.2907
MDL Number:
MFCD00631149
SMILES:
CCOC(=O)c1c(oc2c1cc(O)cc2)c1ccccc1
Properties
Properties
 
BP:
471.3±45.0 °C(Predicted)  
Form:
Liquid  
MP:
154-155 °C(Solv: acetic acid (64-19-7))  
Storage:
Room Temperature;  

Computed Properties
 
Complexity:
364  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
3.9  

Downstream Synthesis Route

[1]Locationinpatent:experimentalpartThirupathaiah;VenkateshwarRao;Ramanna[OrientalJournalofChemistry,2010,vol.26,#4,p.1521-1524]

[2]Locationinpatent:schemeortableMothe,SrinivasaReddy;Susanti,Dewi;Chan,PhilipWaiHong[TetrahedronLetters,2010,vol.51,#16,p.2136-2140]

[3]Zhang,Wei;Lun,Shichun;Wang,Shu-Huan;Jiang,Xing-Wu;Yang,Fan;Tang,Jie;Manson,AbigailL.;Earl,AshleeM.;Gunosewoyo,Hendra;Bishai,WilliamR.;Yu,Li-Fang[JournalofMedicinalChemistry,2018,vol.61,#3,p.791-803]

[4]Yadav,Pratima;Singh,Praveen;Tewari,AshishKumar[BioorganicandMedicinalChemistryLetters,2014,vol.24,#10,p.2251-2255]

[5]CurrentPatentAssignee:HelmholtzAssociation-WO2018/104479,2018,A1Locationinpatent:Page/Pagecolumn41

[6]Grinewetal.[ZhurnalObshcheiKhimii,1957,vol.27,p.821;engl.Ausg.S.897]

[7]Zhang,Yaohuan;Wang,Ruo;Zhang,Tesen;Yan,Weitao;Chen,Yihong;Zhang,Yanping;Zhou,Muyang[ChineseChemicalLetters,2019,vol.30,#3,p.653-655]Diao,Quan-Ping;Guo,Hua;Wang,Gang-Qiang[JournalofHeterocyclicChemistry,2019,vol.56,#5,p.1687-1693]Wang,Yin-Ling;Zhao,Shi-Jia;Liu,Yi;Xu,Zhi[RevueRoumainedeChimie,2019,vol.64,#8,p.687-710]Zou,Yulin[JournalofHeterocyclicChemistry,2020,vol.57,#1,p.510-516]Wang,Yin-Ling;Zhao,Shi-Jia;Liu,Yi;Xu,Zhi[RevueRoumainedeChimie,2021,vol.64,#8,p.687-710]

[8]Gao,Feng;Wang,Tengfei;Gao,Meixiang;Zhang,Xia;Liu,Zhuqing;Zhao,ShiJia;Lv,ZaoSheng;Xiao,Jiaqi[EuropeanJournalofMedicinalChemistry,2019,vol.165,p.323-331]Gao,Feng;Chen,Zijian;Ma,Long;Qiu,Lin;Lin,Jianguo;Lu,Guangming[BioorganicandMedicinalChemistry,2019,vol.27,#12,p.2652-2656]

[9]CurrentPatentAssignee:EASTCHINANORMALUNIVERSITY;CURTINUNIVERSITY;THEJOHNSHOPKINSUNIVERSITY-CN109942523,2019,ALocationinpatent:Paragraph0088;0090;0091

[1]Grinewetal.[ZhurnalObshcheiKhimii,1958,vol.28,p.1853;engl.Ausg.S.1897]

[2]Grinewetal.[ZhurnalObshcheiKhimii,1957,vol.27,p.821;engl.Ausg.S.897]

4897-25-0    4610-75-7   
ethyl5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate 

[1]Patent:WO2018/104479,2018,A1.Locationinpatent:Paragraph41;42

3034-52-4    4610-75-7   
ethyl2-phenyl-5-(thiazol-2-yloxy)benzofuran-3-carboxylate 

[1]Patent:WO2018/104479,2018,A1.Locationinpatent:Page/Pagecolumn42

Literature

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

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