+1 858-523-8231
Login | Register
menu
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
522-70-3,MFCD00869273
Catalog No.:AA00DM0P

522-70-3 | A3

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$358.00   $250.00
- +
5mg
≥98%
in stock  
$1,609.00   $1,126.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00DM0P
Chemical Name:
A3
CAS Number:
522-70-3
Molecular Formula:
C26H36N2O9
Molecular Weight:
520.5720
MDL Number:
MFCD00869273
SMILES:
CCCC[C@H]1C(=O)O[C@H](C)[C@@H](C(=O)O[C@H]([C@@H]1OC(=O)CC(C)C)C)NC(=O)c1cccc(c1O)NC=O
NSC Number:
58239
Properties
Computed Properties
 
Complexity:
818  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
10  
XLogP3:
4.2  

Literature

Title: Synthesis and biological activity of 2-hydroxynicotinoyl-serine-butyl esters related to antibiotic UK-3A.

Journal: Bioorganic & medicinal chemistry letters 20100715

Title: Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide.

Journal: Nature chemical biology 20080701

Title: Short hairpin RNAs targeting Bcl-xL modulate senescence and apoptosis following SN-38 and irinotecan exposure in a colon cancer model.

Journal: Cancer chemotherapy and pharmacology 20071001

Title: Structure-activity relationship studies on UK-2A, a novel antifungal antibiotic from Streptomyces sp. 517-02. Part 5: Roles of the 9-membered dilactone-ring moiety in respiratory inhibition.

Journal: Bioorganic & medicinal chemistry letters 20060615

Title: Gymnoascolides A-C: aromatic butenolides from an Australian isolate of the soil ascomycete Gymnoascus reessii.

Journal: Journal of natural products 20050801

Title: Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908

Title: The BCL2-family of protein ligands as cancer drugs: the next generation of therapeutics.

Journal: Current medicinal chemistry. Anti-cancer agents 20030501

Title: UK-2A, B, C, and D, novel antifungal antibiotics from Streptomyces sp. 517-02 VII. Membrane injury induced by C9-UK-2A, a derivative of UK-2A, in Rhodotorula mucilaginosa IFO 0001.

Journal: The Journal of antibiotics 20020301

Title: Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening.

Journal: Journal of medicinal chemistry 20011206

Title: UK-2A, B, C and D, novel antifungal antibiotics from Streptomyces sp. 517-02. VI(1). Structure-activity relationships of UK-2A.

Journal: The Journal of antibiotics 20010701

Title: Ade Arsianti, et al. Synthesis and anticancer activity of polyhydroxylated 18-membered analogue of antimycin A3. Tetrahedron.Volume 68, Issue 13, 1 April 2012, Pages 2884-2891.

Title: Miyoshi H, et al. Inhibition of electron transport of rat liver mitochondria by unnatural (-)-antimycin A3.

Title: Barrow CJ, et al. Antimycins, inhibitors of ATP-citrate lyase, from a Streptomyces sp. J Antibiot (Tokyo). 1997 Sep;50(9):729-33.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
Submit
SDS
Related Products of 522-70-3
22862-63-1

22862-63-1
Building Blocks
More >
Tags:522-70-3 Molecular Formula|522-70-3 MDL|522-70-3 SMILES|522-70-3 A3
Catalog No.: AA00DM0P
522-70-3,MFCD00869273
522-70-3 | A3
Pack Size： 1mg
Purity： ≥98%
in stock
$358.00 $250.00
Pack Size： 5mg
Purity： ≥98%
in stock
$1,609.00 $1,126.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00DM0P
Chemical Name: A3
CAS Number: 522-70-3
Molecular Formula: C26H36N2O9
Molecular Weight: 520.5720
MDL Number: MFCD00869273
SMILES: CCCC[C@H]1C(=O)O[C@H](C)[C@@H](C(=O)O[C@H]([C@@H]1OC(=O)CC(C)C)C)NC(=O)c1cccc(c1O)NC=O
NSC Number: 58239
Properties
Complexity: 818  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 5  
Heavy Atom Count: 37  
Hydrogen Bond Acceptor Count: 9  
Hydrogen Bond Donor Count: 3  
Rotatable Bond Count: 10  
XLogP3: 4.2  
Literature fold

Title: Synthesis and biological activity of 2-hydroxynicotinoyl-serine-butyl esters related to antibiotic UK-3A.

Journal: Bioorganic & medicinal chemistry letters20100715

Title: Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide.

Journal: Nature chemical biology20080701

Title: Short hairpin RNAs targeting Bcl-xL modulate senescence and apoptosis following SN-38 and irinotecan exposure in a colon cancer model.

Journal: Cancer chemotherapy and pharmacology20071001

Title: Structure-activity relationship studies on UK-2A, a novel antifungal antibiotic from Streptomyces sp. 517-02. Part 5: Roles of the 9-membered dilactone-ring moiety in respiratory inhibition.

Journal: Bioorganic & medicinal chemistry letters20060615

Title: Gymnoascolides A-C: aromatic butenolides from an Australian isolate of the soil ascomycete Gymnoascus reessii.

Journal: Journal of natural products20050801

Title: Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20040908

Title: The BCL2-family of protein ligands as cancer drugs: the next generation of therapeutics.

Journal: Current medicinal chemistry. Anti-cancer agents20030501

Title: UK-2A, B, C, and D, novel antifungal antibiotics from Streptomyces sp. 517-02 VII. Membrane injury induced by C9-UK-2A, a derivative of UK-2A, in Rhodotorula mucilaginosa IFO 0001.

Journal: The Journal of antibiotics20020301

Title: Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening.

Journal: Journal of medicinal chemistry20011206

Title: UK-2A, B, C and D, novel antifungal antibiotics from Streptomyces sp. 517-02. VI(1). Structure-activity relationships of UK-2A.

Journal: The Journal of antibiotics20010701

Title: Ade Arsianti, et al. Synthesis and anticancer activity of polyhydroxylated 18-membered analogue of antimycin A3. Tetrahedron.Volume 68, Issue 13, 1 April 2012, Pages 2884-2891.

Title: Miyoshi H, et al. Inhibition of electron transport of rat liver mitochondria by unnatural (-)-antimycin A3.

Title: Barrow CJ, et al. Antimycins, inhibitors of ATP-citrate lyase, from a Streptomyces sp. J Antibiot (Tokyo). 1997 Sep;50(9):729-33.

Related Products of of 522-70-3
22862-63-1
22862-63-1
Building Blocks More >
55899-42-8
55899-42-8
1,2-Benzenediamine,N-propyl-(9CI)
AA00DNI9 | MFCD07324817
434303-68-1
434303-68-1
2-(4-Bromo-2-methylphenoxy)-N-(3-chloro-4-methylphenyl)acetamide
AA00DPNK | MFCD03708510
544-92-3
544-92-3
Copper(I) cyanide
AA00DRA8 | MFCD00010975
51789-75-4
51789-75-4
2-Cyanobutanoic acid
AA00DU0X | MFCD14544817
433-44-3
433-44-3
2-Fluorobutanoic acid
AA00DVUG | MFCD01737297
439096-49-8
439096-49-8
1H-Pyrrole-2-carboxamide,4-acetyl-N-cycloheptyl-(9CI)
AA00DXWV | MFCD03012651
4872-58-6
4872-58-6
3-Phenyl-4,5-dihydroisoxazole-5-carboxylic acid
AA00E00X | MFCD06011087
5621-43-2
5621-43-2
1,5-Diethyl 2-methylidenepentanedioate
AA00E14E | MFCD28650688
49572-64-7
49572-64-7
3-Iodo-2-methyl-2h-indazole
AA00E3IF | MFCD12828021
474766-30-8
474766-30-8
3-(Propylamino)pyrrolidine-2,5-dione
AA00E6I1 | MFCD02660304
Submit
© 2017 AA BLOCKS, INC. All rights reserved.