58569-55-4,MFCD00076415
Catalog No.:AA00E8N8

58569-55-4 | Met-enkephalin

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
98%
in stock  
$643.00   $450.00
- +
1g
98%
in stock  
$1,555.00   $1,089.00
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5g
98%
in stock  
$3,738.00   $2,617.00
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00E8N8
Chemical Name:
Met-enkephalin
CAS Number:
58569-55-4
Molecular Formula:
C27H35N5O7S
Molecular Weight:
573.6611
MDL Number:
MFCD00076415
SMILES:
CSCC[C@@H](C(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(cc1)O)N
Properties
Computed Properties
 
Complexity:
847  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
40  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
7  
Isotope Atom Count:
0  
Rotatable Bond Count:
16  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-2.1  

Literature

Title: Synthesis of Met-enkephalin by solution-phase peptide synthesis methodology utilizing para-toluene sulfonic acid as N-terminal masking of l-methionine amino acid.

Journal: Chemical biology & drug design 20161201

Title: Orally active opioid μ/δ dual agonist MGM-16, a derivative of the indole alkaloid mitragynine, exhibits potent antiallodynic effect on neuropathic pain in mice.

Journal: The Journal of pharmacology and experimental therapeutics 20140301

Title: Methionine residue acts as a prooxidant in the •OH-induced oxidation of enkephalins.

Journal: The journal of physical chemistry. B 20121018

Title: Opioids inhibit visceral afferent activation of catecholamine neurons in the solitary tract nucleus.

Journal: Neuroscience 20121011

Title: Opiorphin highly improves the specific binding and affinity of MERF and MEGY to rat brain opioid receptors.

Journal: Regulatory peptides 20121010

Title: Induction on differentiation and modulation of bone marrow progenitor of dendritic cell by methionine enkephalin (MENK).

Journal: Cancer immunology, immunotherapy : CII 20121001

Title: Macrophage polarization induced by neuropeptide methionine enkephalin (MENK) promotes tumoricidal responses.

Journal: Cancer immunology, immunotherapy : CII 20121001

Title: Repetitive electroacupuncture causes prolonged increased met-enkephalin expression in the rVLM of conscious rats.

Journal: Autonomic neuroscience : basic & clinical 20120925

Title: The opioid growth factor-opioid growth factor receptor axis: homeostatic regulator of cell proliferation and its implications for health and disease.

Journal: Biochemical pharmacology 20120915

Title: Disturbances in behavior and cortical enkephalin gene expression during the anticipation of ethanol in rats characterized as high drinkers.

Journal: Alcohol (Fayetteville, N.Y.) 20120901

Title: Autocrine regulation of human sperm motility by the met-enkephalin opioid peptide.

Journal: Fertility and sterility 20120901

Title: Supraspinal peroxynitrite modulates pain signaling by suppressing the endogenous opioid pathway.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120808

Title: Cathepsin H functions as an aminopeptidase in secretory vesicles for production of enkephalin and galanin peptide neurotransmitters.

Journal: Journal of neurochemistry 20120801

Title: Enhancement of μ-opioid receptor desensitization by nitric oxide in rat locus coeruleus neurons: involvement of reactive oxygen species.

Journal: The Journal of pharmacology and experimental therapeutics 20120801

Title: Differences in basal and ethanol-induced levels of opioid peptides in Wistar rats from five different suppliers.

Journal: Peptides 20120701

Title: New insights into the neuroanatomical distribution and phylogeny of opioids and POMC-derived peptides in fish.

Journal: General and comparative endocrinology 20120701

Title: Role of bovine adrenal medulla 22 (BAM22) in the pathogenesis of neuropathic pain in rats with spinal nerve ligation.

Journal: European journal of pharmacology 20120615

Title: In vivo visualization of delta opioid receptors upon physiological activation uncovers a distinct internalization profile.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120523

Title: Decreased plasma methionine-enkephalin levels in cluster headache patients.

Journal: American journal of therapeutics 20120501

Title: Changes in spinal cord met-enkephalin levels and mechanical threshold values of pain after pulsed radio frequency in a spared nerve injury rat model.

Journal: Neurological research 20120501

Title: Hepatic Methionine-enkephalin may interfere with response to antiviral therapy in chronic hepatitis C.

Journal: European journal of gastroenterology & hepatology 20120401

Title: Targeting opioidergic pathways as a novel biological treatment for advanced pancreatic cancer.

Journal: Expert review of gastroenterology & hepatology 20120401

Title: Conformational space exploration of Met- and Leu-enkephalin using the MOLS method, molecular dynamics, and Monte Carlo simulation--a comparative study.

Journal: Biopolymers 20120301

Title: Antinociceptive effect of [Met5]enkephalin semicarbazide is not affected by dipeptidyl carboxypeptidase-I.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20120201

Title: Synthesis of quinolinomorphinan-4-ol derivatives as δ opioid receptor agonists.

Journal: Bioorganic & medicinal chemistry 20120115

Title: New insights into opioid regulatory pathways: influence of opioids on Wnt1 expression in zebrafish embryos.

Journal: Neuroscience 20120103

Title: Endogenous endomorphin-2 contributes to spinal ĸ-opioid antinociception.

Journal: Pharmacology 20120101

Title: New findings concerning the mutual action of hormones and receptors.

Journal: In vivo (Athens, Greece) 20120101

Title: Endogenous opioids in wound-site neutrophils of sternotomy patients.

Journal: PloS one 20120101

Title: Kisspeptin neurons co-express met-enkephalin and galanin in the rostral periventricular region of the female mouse hypothalamus.

Journal: The Journal of comparative neurology 20111201

Title: Controlling charge states of peptides through inductive electrospray ionization mass spectrometry.

Journal: Analytical chemistry 20111201

Title: Opioid-sensitive GABA inputs from rostromedial tegmental nucleus synapse onto midbrain dopamine neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20111130

Title: Relaxation mode analysis of a peptide system: comparison with principal component analysis.

Journal: The Journal of chemical physics 20111028

Title: YFa and analogs: investigation of opioid receptors in smooth muscle contraction.

Journal: World journal of gastroenterology 20111028

Title: Multiple replica repulsion technique for efficient conformational sampling of biological systems.

Journal: Biophysical journal 20110817

Title: Blockade of adrenomedullin receptors reverses morphine tolerance and its neurochemical mechanisms.

Journal: Behavioural brain research 20110801

Title: The opioid growth factor (OGF) and low dose naltrexone (LDN) suppress human ovarian cancer progression in mice.

Journal: Gynecologic oncology 20110801

Title: Comparative analysis of Met-enkephalin, galanin and GABA immunoreactivity in the developing trout preoptic-hypophyseal system.

Journal: General and comparative endocrinology 20110801

Title: The action of a synthetic derivative of Met5-enkephalin-Arg6-Phe7 on behavioral and endocrine responses.

Journal: Peptides 20110801

Title: Microdialysis and mass spectrometric monitoring of dopamine and enkephalins in the globus pallidus reveal reciprocal interactions that regulate movement.

Journal: Journal of neurochemistry 20110701

Title: Oxytocin in the periaqueductal gray participates in pain modulation in the rat by influencing endogenous opiate peptides.

Journal: Peptides 20110601

Title: Mu-opioid receptor densities are depleted in regions implicated in agonistic and sexual behavior in male European starlings (Sturnus vulgaris) defending nest sites and courting females.

Journal: Behavioural brain research 20110516

Title: T lymphocyte proliferation is suppressed by the opioid growth factor ([Met(5)]-enkephalin)-opioid growth factor receptor axis: implication for the treatment of autoimmune diseases.

Journal: Immunobiology 20110501

Title: Decrease of lymphoproliferative response by amphetamine is mediated by dopamine from the nucleus accumbens: influence on splenic met-enkephalin levels.

Journal: Brain, behavior, and immunity 20110501

Title: Functional modulation of the pathway between dendritic cells (DCs) and CD4+T cells by the neuropeptide: methionine enkephalin (MENK).

Journal: Peptides 20110501

Title: HPLC/MS/MS for quantification of two types of neurotransmitters in rat brain and application: myocardial ischemia and protection of Sheng-Mai-San.

Journal: Journal of pharmaceutical and biomedical analysis 20110428

Title: Regular exercise reverses sensory hypersensitivity in a rat neuropathic pain model: role of endogenous opioids.

Journal: Anesthesiology 20110401

Title: Phylogenetic diversity and functional efficacy of the C-terminally expressed heptapeptide unit in the opioid precursor polypeptide proenkephalin A.

Journal: Neuroscience 20110331

Title: Prevention and diminished expression of experimental autoimmune encephalomyelitis by low dose naltrexone (LDN) or opioid growth factor (OGF) for an extended period: Therapeutic implications for multiple sclerosis.

Journal: Brain research 20110324

Title: Immune modulation in response to stress and relaxation.

Journal: Pakistan journal of biological sciences : PJBS 20110315

Title: Modulation by endogenously released ATP and opioids of chromaffin cell calcium channels in mouse adrenal slices.

Journal: American journal of physiology. Cell physiology 20110301

Title: Regulated proenkephalin expression in human skin and cultured skin cells.

Journal: The Journal of investigative dermatology 20110301

Title: Sympatholytic delta-2 opioid receptors moderate ganglionic vasomotor control.

Journal: Experimental biology and medicine (Maywood, N.J.) 20110301

Title: Intestinal immune response of Silurus glanis and Barbus barbus naturally infected with Pomphorhynchus laevis (Acanthocephala).

Journal: Parasite immunology 20110201

Title: B lymphocyte proliferation is suppressed by the opioid growth factor-opioid growth factor receptor axis: Implication for the treatment of autoimmune diseases.

Journal: Immunobiology 20110101

Title: Degradation kinetics of methionine5-enkephalin by cerebrospinal fluid: in vitro studies.

Journal: American journal of therapeutics 20110101

Title: Met-enkephalins in patients with inflammatory bowel diseases.

Journal: Advances in medical sciences 20110101

Title: Predicting antitumor activity of peptides by consensus of regression models trained on a small data sample.

Journal: International journal of molecular sciences 20110101

Title: Tolerance to the antinociceptive effect of morphine in the absence of short-term presynaptic desensitization in rat periaqueductal gray neurons.

Journal: The Journal of pharmacology and experimental therapeutics 20101201

Title: Investigation of the pyrolysis products of methionine-enkephalin-Arg-Gly-Leu using liquid chromatography-tandem mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20101101

Title: Regulation of Tenon's capsule fibroblast cell proliferation by the opioid growth factor and the opioid growth factor receptor axis.

Journal: Investigative ophthalmology & visual science 20101001

Title: Opioid modulation of cell proliferation in the ventricular zone of adult zebra finches (Taenopygia guttata).

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20101001

Title: Effects of acute ethanol administration on methionine-enkephalin expression and release in regions of the rat brain.

Journal: Neuropeptides 20101001

Title: Internalization of the opioid growth factor, [Met5]-enkephalin, is dependent on clathrin-mediated endocytosis for downregulation of cell proliferation.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100901

Title: Rationally designed chimeric peptide of met-enkephalin and FMRFa-[D-Ala2,p-Cl-Phe4]YFa induce multiple opioid receptors mediated antinociception and up-regulate their expression.

Journal: European journal of pharmacology 20100725

Title: Non-suicidal self-injurious behavior, endogenous opioids and monoamine neurotransmitters.

Journal: Journal of affective disorders 20100701

Title: [Methionine-enkephalin (Met5-Enk) and leucine-enkephalin (Leu5-Enk)].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20100701

Title: Modulation of feeding and locomotion through mu and delta opioid receptor signaling in the nucleus accumbens.

Journal: Neuropeptides 20100601

Title: Delivery of neuropeptides from the periphery to the brain: studies with enkephalin.

Journal: ACS chemical neuroscience 20100519

Title: Analogues of both Leu- and Met-enkephalin containing a constrained dipeptide isostere prepared from a Baylis-Hillman adduct.

Journal: Amino acids 20100401

Title: Computational structure-activity study directs synthesis of novel antitumor enkephalin analogs.

Journal: Amino acids 20100401

Title: Effect of chronic intra-peritoneally administered chimeric peptide of met-enkephalin and FMRFa-[D-Ala2]YFa-on antinociception and opioid receptor regulation.

Journal: European journal of pain (London, England) 20100301

Title: CD10 enhances metastasis of colorectal cancer by abrogating the anti-tumoural effect of methionine-enkephalin in the liver.

Journal: Gut 20100301

Title: Topical application of naltrexone facilitates reepithelialization of the cornea in diabetic rabbits.

Journal: Brain research bulletin 20100215

Title: Opioids in the hypothalamus control dopamine and acetylcholine levels in the nucleus accumbens.

Journal: Brain research 20100202

Title: Opioids in the hypothalamic paraventricular nucleus stimulate ethanol intake.

Journal: Alcoholism, clinical and experimental research 20100201

Title: Solution structural investigation and conformation-activity relationship of BAM8-22 by NMR and molecular dynamics simulations.

Journal: Bioorganic & medicinal chemistry letters 20100201

Title: Opioid growth factor suppresses expression of experimental autoimmune encephalomyelitis.

Journal: Brain research 20100115

Title: Various drug delivery approaches to the central nervous system.

Journal: Expert opinion on drug delivery 20100101

Title: Plasma endogenous enkephalin levels in early systemic sclerosis: clinical and laboratory associations.

Journal: Clinical and experimental rheumatology 20100101

Title: [M-Enk expressing in the lamina II of cat spinal cord after deafferentation].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20091101

Title: Opioid growth factor-opioid growth factor receptor axis is a physiological determinant of cell proliferation in diverse human cancers.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20091001

Title: Endogenous peptide: Met-enkephalin-Arg-Phe, differently regulate expression of opioid receptors on chronic treatment.

Journal: Neuropeptides 20091001

Title: Segregation of met-enkephalin from vesicular acetylcholine transporter and choline acetyltransferase in sympathetic preganglionic varicosities mostly lacking synaptophysin and synaptotagmin.

Journal: Neuroscience 20090929

Title: Multiple Markov transition matrix method: obtaining the stationary probability distribution from multiple simulations.

Journal: Journal of computational chemistry 20090901

Title: Anticonvulsant Met-enkephalin analogues containing backbone spacers reveal alternative non-opioid signaling in the brain.

Journal: ACS chemical biology 20090821

Title: Release of endogenous opioids from duodenal enteroendocrine cells requires Trpm5.

Journal: Gastroenterology 20090801

Title: Arginine vasopressin antinociception in the rat nucleus raphe magnus is involved in the endogenous opiate peptide and serotonin system.

Journal: Peptides 20090701

Title: Buprenorphine is a weak partial agonist that inhibits opioid receptor desensitization.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090603

Title: Cell proliferation of human ovarian cancer is regulated by the opioid growth factor-opioid growth factor receptor axis.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090601

Title: Effect of acute ethanol administration on the release of opioid peptides from the midbrain including the ventral tegmental area.

Journal: Alcoholism, clinical and experimental research 20090601

Title: G protein independent phosphorylation and internalization of the delta-opioid receptor.

Journal: Journal of neurochemistry 20090601

Title: Cathepsin K generates enkephalin from beta-endorphin: a new mechanism with possible relevance for schizophrenia.

Journal: Neurochemistry international 20090601

Title: Design and synthesis of novel delta opioid receptor agonists and their pharmacologies.

Journal: Bioorganic & medicinal chemistry letters 20090515

Title: Comparison of predicted native structures of Met-enkephalin based on various accessible-surface-area solvent models.

Journal: Journal of computational chemistry 20090501

Title: Antinociception by neutrophil-derived opioid peptides in noninflamed tissue--role of hypertonicity and the perineurium.

Journal: Brain, behavior, and immunity 20090501

Title: Regulation of cell proliferation by the OGF-OGFr axis is dependent on nuclear localization signals.

Journal: Experimental biology and medicine (Maywood, N.J.) 20090501

Title: Intrathecal transplantation of autologous macrophages genetically modified to secrete proenkephalin ameliorated hyperalgesia and allodynia following peripheral nerve injury in rats.

Journal: Neuroscience research 20090501

Title: [Distribution of met-enkephalin expression in the visual pathway. Experimental study by inmunocytochemistry].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20090501

Title: Sensitization to amphetamine occurs simultaneously at immune level and in met-enkephalin of the nucleus accumbens and spleen: an involved NMDA glutamatergic mechanism.

Journal: Brain, behavior, and immunity 20090501

Title: Capillary electrophoresis-mass spectrometry using an in-line sol-gel concentrator for the determination of methionine enkephalin in cerebrospinal fluid.

Journal: Talanta 20090430

Title: Does the endogenous opiate system play a role in the Restless Legs Syndrome? A pilot post-mortem study.

Journal: Journal of the neurological sciences 20090415

Title: Hypertensive state, independent of hypertrophy, exhibits an attenuated decrease in systolic function on cardiac kappa-opioid receptor stimulation.

Journal: American journal of physiology. Heart and circulatory physiology 20090401

Title: Gene therapy for pancreatitis pain.

Journal: Gene therapy 20090401

Title: Mycobacteria attenuate nociceptive responses by formyl peptide receptor triggered opioid peptide release from neutrophils.

Journal: PLoS pathogens 20090401

Title: Practical aspects of in vivo detection of neuropeptides by microdialysis coupled off-line to capillary LC with multistage MS.

Journal: Analytical chemistry 20090315

Title: Bounding the electrostatic free energies associated with linear continuum models of molecular solvation.

Journal: The Journal of chemical physics 20090314

Title: Two distinct mechanisms mediate acute mu-opioid receptor desensitization in native neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090311

Title: Methionine-enkephalin secreted by human colorectal cancer cells suppresses T lymphocytes.

Journal: Cancer science 20090301

Title: Efficient evaluation of sampling quality of molecular dynamics simulations by clustering of dihedral torsion angles and Sammon mapping.

Journal: Journal of computational chemistry 20090201

Title: A prolonged nitric oxide-dependent, opioid-mediated antinociceptive effect of hyperbaric oxygen in mice.

Journal: The journal of pain : official journal of the American Pain Society 20090201

Title: Network architecture of gap junction-coupled neuronal linkage in the striatum.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090128

Title: Neurokinin 1 receptors regulate morphine-induced endocytosis and desensitization of mu-opioid receptors in CNS neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090107

Title: The effects of selective breeding for differential rates of 50-kHz ultrasonic vocalizations on emotional behavior in rats.

Journal: Developmental psychobiology 20090101

Title: Activation of delta-opioid receptors reduces excitatory input to putative gustatory cells within the nucleus of the solitary tract.

Journal: Journal of neurophysiology 20090101

Title: Dilution-free analysis from picoliter droplets by nano-electrospray ionization mass spectrometry.

Journal: Angewandte Chemie (International ed. in English) 20090101

Title: Freezing of enkephalinergic functions by multiple noxious foci: a source of pain sensitization?

Journal: PloS one 20090101

Title: Bacitracin-sensitive aminopeptidase(s) degradation of methionine(5)-enkephalin by human brain putamen and hippocampus preparations: inhibition by phenothiazine drugs.

Journal: American journal of therapeutics 20090101

Title: Growth inhibition of thyroid follicular cell-derived cancers by the opioid growth factor (OGF) - opioid growth factor receptor (OGFr) axis.

Journal: BMC cancer 20090101

Title: Effects of acute ethanol on opioid peptide release in the central amygdala: an in vivo microdialysis study.

Journal: Psychopharmacology 20081201

Title: Lack of tolerance and morphine-induced cross-tolerance to the analgesia of chimeric peptide of Met-enkephalin and FMRFa.

Journal: Peptides 20081201

Title: Folding proteins by first-passage-times-optimized replica exchange.

Journal: Physical review. E, Statistical, nonlinear, and soft matter physics 20081201

Title: Dynamic changes of the endogenous cannabinoid and opioid mesocorticolimbic systems during adolescence: THC effects.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20081101

Title: Expression of opioid growth factor (OGF)-OGF receptor (OGFr) axis in human nonmedullary thyroid cancer.

Journal: Thyroid : official journal of the American Thyroid Association 20081101

Title: Mu-opioid receptor activation in live cells.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20081001

Title: Possible autocrine enkephalin regulation of catecholamine release in human pheochromocytoma cells.

Journal: Life sciences 20080912

Title: Tolerance to repeated morphine administration is associated with increased potency of opioid agonists.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080901

Title: Distinct morphological and immunohistochemical features and different growth rates among four human neuroblastomas heterotransplanted into nude mice.

Journal: Medical molecular morphology 20080901

Title: Antinociception produced by 14,15-epoxyeicosatrienoic acid is mediated by the activation of beta-endorphin and met-enkephalin in the rat ventrolateral periaqueductal gray.

Journal: The Journal of pharmacology and experimental therapeutics 20080801

Title: Effect of chronic administration of morphine on the expression of bovine adrenal medulla 22-like immunoreactivity in the spinal cord of rats.

Journal: European journal of pharmacology 20080728

Title: An in vitro comparison of microdialysis relative recovery of Met- and Leu-enkephalin using cyclodextrins and antibodies as affinity agents.

Journal: Analytica chimica acta 20080714

Title: Natural linear-scaled coupled-cluster theory with local transferable triple excitations: applications to peptides.

Journal: The journal of physical chemistry. A 20080703

Title: Estradiol abolishes reduction in cell death by the opioid agonist Met5-enkephalin after oxygen glucose deprivation in isolated cardiomyocytes from both sexes.

Journal: American journal of physiology. Heart and circulatory physiology 20080701

Title: Capillary electrophoresis chemiluminescent detection system equipped with a two-step postcolumn flow interface for detection of some enkephalin-related peptides labeled with acridinium ester.

Journal: Electrophoresis 20080601

Title: YFa, a chimeric opioid peptide, induces kappa-specific antinociception with no tolerance development during 6 days of chronic treatment.

Journal: Journal of neuroscience research 20080515

Title: Enkephalin elevations contribute to neuronal and behavioral impairments in a transgenic mouse model of Alzheimer's disease.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080507

Title: Presynaptic actions of opioid receptor agonists in ventromedial hypothalamic neurons in estrogen- and oil-treated female mice.

Journal: Neuroscience 20080409

Title: The impact of postnatal environment on opioid peptides in young and adult male Wistar rats.

Journal: Neuropeptides 20080401

Title: Methionine-enkephalin modulation of hydrogen peroxide (H2O2) release by rat peritoneal macrophages involves different types of opioid receptors.

Journal: Neuropeptides 20080401

Title: Evaluation of a novel aminopeptidase N inhibitor, in vitro, using two assay systems.

Journal: Journal of enzyme inhibition and medicinal chemistry 20080401

Title: Role of endogenous opioids in modulating HSC activity in vitro and liver fibrosis in vivo.

Journal: Gut 20080301

Title: Reactivity and oxidative potential of fructose and glucose in enkephalin-sugar model systems.

Journal: Amino acids 20080201

Title: Involvement of spinal Met-enkephalin in nicotine-induced antinociception in mice.

Journal: Brain research 20080116

Title: In vitro methionine5-enkephalin degradation kinetics by human brain preparations.

Journal: Neurochemical research 20080101

Title: Liver derived endogenous opioids may interfere with the therapeutic effect of interferon in chronic hepatitis C.

Journal: Medical hypotheses 20080101

Title: Sex differences in the mechanism of Met5-enkephalin-induced cardioprotection: role of PI3K/Akt.

Journal: American journal of physiology. Heart and circulatory physiology 20080101

Title: The OGF-OGFr axis utilizes the p21 pathway to restrict progression of human pancreatic cancer.

Journal: Molecular cancer 20080101

Title: Degradation kinetics of methionine5-enkephalin by select brain areas from patients with chronic schizophrenia.

Journal: American journal of therapeutics 20080101

Title: [Pharmacodynamic properties of a combination of met-enkephalin and alpha 1-13 adrenocorticotropic hormone].

Journal: Medicinski arhiv 20080101

Title: Differential activation of enkephalin, galanin, somatostatin, NPY, and VIP neuropeptide production by stimulators of protein kinases A and C in neuroendocrine chromaffin cells.

Journal: Neuropeptides 20080101

Title: Human hepatic met-enkephalin and delta opioid receptor-1 immunoreactivities in viral and autoimmune hepatitis.

Journal: Annals of hepatology 20080101

Title: Compartmental loss of striatal medium spiny neurons in multiple system atrophy of parkinsonian type.

Journal: Movement disorders : official journal of the Movement Disorder Society 20071201

Title: Opioids and migration, chemotaxis, invasion, and adhesion of human cancer cells.

Journal: Neuropeptides 20071201

Title: Endogenous heptapeptide Met-enkephalin-Gly-Tyr binds differentially to duplicate delta opioid receptors from zebrafish.

Journal: Peptides 20071201

Title: Augmented myocardial methionine-enkephalin in a murine model of cardiac angiotensin II-overexpression.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20071201

Title: On the structural convergence of biomolecular simulations by determination of the effective sample size.

Journal: The journal of physical chemistry. B 20071108

Title: CXCR1/2 ligands induce p38 MAPK-dependent translocation and release of opioid peptides from primary granules in vitro and in vivo.

Journal: Brain, behavior, and immunity 20071101

Title: The opioid growth factor (OGF)-OGF receptor axis uses the p16 pathway to inhibit head and neck cancer.

Journal: Cancer research 20071101

Title: Hamiltonian and distance replica exchange method studies of Met-enkephalin.

Journal: The journal of physical chemistry. B 20071025

Title: Live cell monitoring of mu-opioid receptor-mediated G-protein activation reveals strong biological activity of close morphine biosynthetic precursors.

Journal: The Journal of biological chemistry 20070914

Title: The involvement of spinal bovine adrenal medulla 22-like peptide, the proenkephalin derivative, in modulation of nociceptive processing.

Journal: The European journal of neuroscience 20070901

Title: The enhancing effects of peptidase inhibitors on the antinociceptive action of [Met5]enkephalin-Arg6-Phe7 in rats.

Journal: Journal of pharmacological sciences 20070901

Title: Microscopic understanding of preferential exclusion of compatible solute ectoine: direct interaction and hydration alteration.

Journal: The journal of physical chemistry. B 20070830

Title: Superoxide radical anions protect enkephalin from oxidation if the amine group is blocked.

Journal: Free radical biology & medicine 20070715

Title: Arginine vasopressin induces periaqueductal gray release of enkephalin and endorphin relating to pain modulation in the rat.

Journal: Regulatory peptides 20070705

Title: Sensitisation of TRPV1 in rat sensory neurones by activation of SNSRs.

Journal: Neuroscience letters 20070705

Title: Influence of pain treatment by epidural fentanyl and bupivacaine on homing of opioid-containing leukocytes to surgical wounds.

Journal: Brain, behavior, and immunity 20070701

Title: Beta-endorphin, Met-enkephalin and corresponding opioid receptors within synovium of patients with joint trauma, osteoarthritis and rheumatoid arthritis.

Journal: Annals of the rheumatic diseases 20070701

Title: Ethanol-induced effects on opioid peptides in adult male Wistar rats are dependent on early environmental factors.

Journal: Neuroscience 20070525

Title: Further studies of tyrosine surrogates in opioid receptor peptide ligands.

Journal: Bioorganic & medicinal chemistry letters 20070501

Title: Opioid peptides as possible neuromodulators in the frog peripheral nerve system.

Journal: Neuropeptides 20070401

Title: The hop cassette of the PAC1 receptor confers coupling to Ca2+ elevation required for pituitary adenylate cyclase-activating polypeptide-evoked neurosecretion.

Journal: The Journal of biological chemistry 20070316

Title: Sensory neuron-specific receptor agonist BAM8-22 inhibits the development and expression of tolerance to morphine in rats.

Journal: Behavioural brain research 20070312

Title: Involvement of delta-and mu-opioid receptors in the delayed cerebral ischemic tolerance induced by repeated electroacupuncture preconditioning in rats.

Journal: Chinese medical journal 20070305

Title: Overexpression of the opioid growth factor receptor downregulates cell proliferation of human squamous carcinoma cells of the head and neck.

Journal: International journal of molecular medicine 20070301

Title: The influence of stress and methionine-enkephalin on macrophage functions in two inbred rat strains.

Journal: Life sciences 20070213

Title: Electrophysiological properties of catecholaminergic neurons in the norepinephrine-deficient mouse.

Journal: Neuroscience 20070209

Title: GABAergic interneurons facilitate mossy fiber excitability in the developing hippocampus.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070207

Title: Morphine priming in rats with chronic inflammation reveals a dichotomy between antihyperalgesic and antinociceptive properties of deltorphin.

Journal: Neuroscience 20070105

Title: Conformational stability and three-dimensional model of the delta-opioid pharmacophore for the extended antiparallel dimer structure of Met-enkephalin in water.

Journal: Journal of molecular modeling 20070101

Title: Reactions of hydrogen atoms with met-enkephalin and related peptides.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

Title: Distinction of neurochemistry between the cores and their shells of auditory nuclei in tetrapod species.

Journal: Brain, behavior and evolution 20070101

Title: Differences in neurogenesis differentiate between core and shell regions of auditory nuclei in the turtle (Pelodiscus sinensis): evolutionary implications.

Journal: Brain, behavior and evolution 20070101

Title: RB101-mediated protection of endogenous opioids: potential therapeutic utility?

Journal: CNS drug reviews 20070101

Title: Plasma met-enkephalin, beta-endorphin and leu-enkephalin levels in human hepatic encephalopathy.

Journal: Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit 20070101

Title: Dependence of the analgesic activities of dermorphin, metenkephalin, and dynorphin A on the ambient temperature.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20070101

Title: [Subacute toxicity study of combination of adrenocorticotropine 1-13 and met-enkephalin].

Journal: Medicinski arhiv 20070101

Title: Human opioid peptide Met-enkephalin binds to anionic phosphatidylserine in high preference to zwitterionic phosphatidylcholine: natural-abundance 13C NMR study on the binding state in large unilamellar vesicles.

Journal: Biochemistry 20061226

Title: Arginine vasopressin enhances periaqueductal gray synthesis and secretion of enkephalin and endorphin in the rat.

Journal: Brain research bulletin 20061211

Title: Repeated delta1-opioid receptor stimulation reduces delta2-opioid receptor responses in the SA node.

Journal: American journal of physiology. Heart and circulatory physiology 20061101

Title: The monosialosyl ganglioside GM-1 reduces the vagolytic efficacy of delta2-opioid receptor stimulation.

Journal: American journal of physiology. Heart and circulatory physiology 20061101

Title: Conformational study of Met-enkephalin based on the ECEPP force fields.

Journal: Biophysical journal 20061001

Title: The distribution of substance P and met-enkephalin in vocal control nuclei among oscine species and its relation to song complexity.

Journal: Behavioural brain research 20060925

Title: Choline acetyl transferase and neuropeptide immunoreactivities are colocalized in somata, but preferentially localized in distinct axon fibers and boutons of cat sympathetic preganglionic neurons.

Journal: Synapse (New York, N.Y.) 20060915

Title: Vagal afferent control of opioidergic effects in rat brainstem circuits.

Journal: The Journal of physiology 20060915

Title: Effects of chronic ethanol administration on brain interstitial fluid levels of Methionine-enkephalin as measured by microdialysis in vivo.

Journal: Peptides 20060901

Title: Amphetamine triggers an increase in met-enkephalin simultaneously in brain areas and immune cells.

Journal: Journal of neuroimmunology 20060901

Title: Kappa-opioid receptors mediate cardioprotection by remote preconditioning.

Journal: Anesthesiology 20060901

Title: Opiate receptor binding properties of morphine-, dihydromorphine-, and codeine 6-O-sulfate ester congeners.

Journal: Bioorganic & medicinal chemistry letters 20060815

Title: Simultaneous activation of the delta opioid receptor (deltaOR)/sensory neuron-specific receptor-4 (SNSR-4) hetero-oligomer by the mixed bivalent agonist bovine adrenal medulla peptide 22 activates SNSR-4 but inhibits deltaOR signaling.

Journal: Molecular pharmacology 20060801

Title: Ab initio protein fold prediction using evolutionary algorithms: influence of design and control parameters on performance.

Journal: Journal of computational chemistry 20060801

Title: Met5-enkephalin-Arg6-Phe7 (MEAP): a cardioprotective hormonal opioid.

Journal: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20060801

Title: Opioid growth factor receptor is unaltered with the progression of human pancreatic and colon cancers.

Journal: International journal of oncology 20060801

Title: Chimeric peptide of met-enkephalin and FMRFa: effect of chlorination on conformation and analgesia.

Journal: Neuroscience letters 20060731

Title: Effect of starvation on Fos and neuropeptide immunoreactivities in the brain and pituitary gland of Xenopus laevis.

Journal: General and comparative endocrinology 20060701

Title: Enkephalinergic afferents of the centromedial amygdala in the rat.

Journal: The Journal of comparative neurology 20060620

Title: Evaluation of efficiency of reference potential spatial warping algorithm in conformational sampling of peptides.

Journal: The Journal of chemical physics 20060607

Title: Proenkephalin peptide F immunoreactivity in different circulatory biocompartments after exercise.

Journal: Peptides 20060601

Title: Endogenous opioid-mediated antinociception in cholestatic mice is peripherally, not centrally, mediated.

Journal: Journal of hepatology 20060601

Title: Variations in opioid peptide levels during the estrous cycle in Sprague-Dawley rats.

Journal: Neuropeptides 20060601

Title: A pulsed field gradient NMR diffusion investigation of enkephalin peptide-sodium dodecyl sulfate micelle association.

Journal: Magnetic resonance in chemistry : MRC 20060601

Title: Tumor-cell-targeted methionine-enkephalin analogues containing unnatural amino acids: design, synthesis, and in vitro antitumor activity.

Journal: Journal of medicinal chemistry 20060601

Title: Vibrational dynamics of morphine in relation to Leu5--and Met5-enkephalins.

Journal: Indian journal of biochemistry & biophysics 20060601

Title: Delta and mu opioid receptors from the brain of a urodele amphibian, the rough-skinned newt Taricha granulosa: cloning, heterologous expression, and pharmacological characterization.

Journal: General and comparative endocrinology 20060501

Title: Endogenous opioids modulate the growth of the biliary tree in the course of cholestasis.

Journal: Gastroenterology 20060501

Title: Capillary electrophoretic competitive immunoassay with laser-induced fluorescence detection for methionine-enkephalin.

Journal: Journal of chromatography. A 20060414

Title: Preproenkephalin targeted antisenses cross the blood-brain barrier to reduce brain methionine enkephalin levels and increase voluntary ethanol drinking.

Journal: Peptides 20060401

Title: Cell therapy of pain: Characterization of human fetal chromaffin cells at early adrenal medulla development.

Journal: Experimental neurology 20060401

Title: Vagotonic effects of enkephalin are not mediated by sympatholytic mechanisms.

Journal: Experimental biology and medicine (Maywood, N.J.) 20060401

Title: Bovine adrenal medulla 22 reverses antinociceptive morphine tolerance in the rat.

Journal: Behavioural brain research 20060315

Title: Theoretical studies of transition states by the multioverlap molecular dynamics methods.

Journal: The Journal of chemical physics 20060314

Title: Influence of the menstrual cycle on proenkephalin peptide F responses to maximal cycle exercise.

Journal: European journal of applied physiology 20060301

Title: A new method to determine electrostatic potential around a macromolecule in solution from molecular wave functions.

Journal: Journal of computational chemistry 20060301

Title: Complex regional pain syndrome and methionine-enkephalin.

Journal: Clinical chemistry 20060301

Title: Determination of enkephalin peptides by nonaqueous capillary electrophoresis with electrochemical detection.

Journal: Electrophoresis 20060301

Title: The superior colliculus of the camel: a neuronal-specific nuclear protein (NeuN) and neuropeptide study.

Journal: Journal of anatomy 20060201

Title: Involvement of caspase-3 pathway in anti-apoptotic action of methionine enkephalin on CEM x 174 cells in prolonged infection with simian immunodeficiency virus in vitro.

Journal: Cell biology international 20060201

Title: Methionine-enkephalin modulated regulation of oxidant/antioxidant status in liver of CBA mice.

Journal: Biogerontology 20060201

Title: Synthesis, conformational and pharmacological studies of glycosylated chimeric peptides of Met-enkephalin and FMRFa.

Journal: Brain research bulletin 20060130

Title: A new electrochemical HPLC method for analysis of enkephalins and endomorphins.

Journal: Journal of neuroscience methods 20060115

Title: Perinatal ethanol exposure alters met-enkephalin levels of male and female rats.

Journal: Neurotoxicology and teratology 20060101

Title: Genetically engineered human mesenchymal stem cells produce met-enkephalin at augmented higher levels in vitro.

Journal: Cell transplantation 20060101

Title: Endogenous signaling complexity in neuropeptides- leucine- and methionine-enkephalin.

Journal: Cellular and molecular neurobiology 20060101

Title: Aspects of central and peripheral regulation of reproduction in mammals.

Journal: Reproductive biology 20060101

Title: Effect of prolonged progesterone treatment on the proenkephalin mRNA gene expression and enkephalins concentration in the sheep brain.

Journal: Reproductive biology 20060101

Title: Met-enkephalin in the liver as a marker of hepatocellular damage in chronic viral hepatitis type B and C.

Journal: Advances in medical sciences 20060101

Title: Validation of the l-dopa-induced dyskinesia in the 6-OHDA model and evaluation of the effects of selective dopamine receptor agonists and antagonists.

Journal: Brain research bulletin 20051215

Title: Met-enkephalin effects on histamine-induced bronchoconstriction in guinea pigs.

Journal: Collegium antropologicum 20051201

Title: Immunohistochemical reactions of receptors to met-enkephalin, VIP, substance P, and CGRP located on Merkel cells in the rat sinus hair follicle.

Journal: Archives of histology and cytology 20051201

Title: Substrate access to the active sites in aminopeptidase T, a representative of a new metallopeptidase clan.

Journal: Journal of molecular biology 20051125

Title: Energy landscapes and properties of biomolecules.

Journal: Physical biology 20051109

Title: Combination chemotherapy with gemcitabine and biotherapy with opioid growth factor (OGF) enhances the growth inhibition of pancreatic adenocarcinoma.

Journal: Cancer chemotherapy and pharmacology 20051101

Title: Postsynaptic actions of substance P on rat periaqueductal grey neurons in vitro.

Journal: Neuropharmacology 20051001

Title: Ischemic preconditioning increases the bioavailability of cardiac enkephalins.

Journal: American journal of physiology. Heart and circulatory physiology 20051001

Title: Opioids and differentiation in human cancer cells.

Journal: Neuropeptides 20051001

Title: A microdialysis profile of Met-enkephalin release in the rat nucleus accumbens following alcohol administration.

Journal: Alcoholism, clinical and experimental research 20051001

Title: Attenuation of pain perception after transposition of the greater omentum to the cauda equina region of rats--a preliminary observation.

Journal: Neurological research 20050901

Title: Role of methionine-enkephalin on the regulation of carbohydrate metabolism in the rice field crab Oziotelphusa senex senex.

Journal: Comptes rendus biologies 20050901

Title: Capillary liquid chromatography and tandem mass spectrometry for the quantification of enkephalins in cerebrospinal fluid.

Journal: Journal of separation science 20050901

Title: Binding profile of the endogenous novel heptapeptide Met-enkephalin-Gly-tyr in zebrafish and rat brain.

Journal: The Journal of pharmacology and experimental therapeutics 20050801

Title: [Methionine-enkephalin (Met-Enk) and leucine-enkephalin (Leu-Enk)].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050801

Title: The influence of cell growth media on the stability and antitumour activity of methionine enkephalin.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20050701

Title: Opioid growth factor enhances tumor growth inhibition and increases the survival of paclitaxel-treated mice with squamous cell carcinoma of the head and neck.

Journal: Cancer chemotherapy and pharmacology 20050701

Title: Inhibition of neuronal nitric oxide synthase attenuates the development of morphine tolerance in rats.

Journal: Synapse (New York, N.Y.) 20050701

Title: Effects of maternal separation on voluntary ethanol intake and brain peptide systems in female Wistar rats.

Journal: Pharmacology, biochemistry, and behavior 20050701

Title: Particle-mediated gene transfer of opioid growth factor receptor cDNA regulates cell proliferation of the corneal epithelium.

Journal: Cornea 20050701

Title: Rugged Metropolis sampling with simultaneous updating of two dynamical variables.

Journal: Physical review. E, Statistical, nonlinear, and soft matter physics 20050701

Title: Met-enkephalin involvement in morphine-modulated peritonitis in swiss mice.

Journal: Mediators of inflammation 20050609

Title: Influence of naloxone on catecholamine release evoked by nicotinic receptor stimulation in the isolated rat adrenal gland.

Journal: Archives of pharmacal research 20050601

Title: Lymphocytic ppENKmRNA, MEK-IR, and Dyn-IR in electroacupuncture.

Journal: Bulletin of experimental biology and medicine 20050601

Title: Maternal deprivation increases vulnerability to morphine dependence and disturbs the enkephalinergic system in adulthood.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050504

Title: A simple method for faster nonbonded force evaluations.

Journal: Journal of computational chemistry 20050501

Title: Effects of met-enkephalin on cell proliferation in different models of adrenocortical-cell growth.

Journal: International journal of molecular medicine 20050501

Title: [Met-enkephalin in the cerebrospinal fluid as an indicator of central nervous system injury in meningitis and encephalitis].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20050501

Title: Proopiomelanocortin neurons in nucleus tractus solitarius are activated by visceral afferents: regulation by cholecystokinin and opioids.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050406

Title: Long-term infusion of Met5-enkephalin fails to protect murine hearts against ischemia-reperfusion injury.

Journal: American journal of physiology. Heart and circulatory physiology 20050401

Title: Met5-enkephalin-induced cardioprotection occurs via transactivation of EGFR and activation of PI3K.

Journal: American journal of physiology. Heart and circulatory physiology 20050401

Title: Differential mechanisms of antianalgesia induced by endomorphin-1 and endomorphin-2 in the ventral periaqueductal gray of the rat.

Journal: The Journal of pharmacology and experimental therapeutics 20050301

Title: Enhanced growth inhibition of squamous cell carcinoma of the head and neck by combination therapy of paclitaxel and opioid growth factor.

Journal: International journal of oncology 20050301

Title: Withdrawal following sufentanil/propofol and sufentanil/midazolam. Sedation in surgical ICU patients: correlation with central nervous parameters and endogenous opioids.

Journal: Intensive care medicine 20050301

Title: Substance P and opioid peptidergic innervation of the anterior eye segment of the rat: an immunohistochemical study.

Journal: Journal of anatomy 20050301

Title: Hypotensive effect of novel chimeric peptides of met-enkephalin and FMRFa.

Journal: Regulatory peptides 20050215

Title: Peptidergic neuromodulation of the lumbar locomotor network in the neonatal rat spinal cord.

Journal: Peptides 20050201

Title: Capillary liquid chromatography with MS3 for the determination of enkephalins in microdialysis samples from the striatum of anesthetized and freely-moving rats.

Journal: Journal of mass spectrometry : JMS 20050201

Title: Selective involvement of opioids in the mechanisms of synapse-specific plasticity in the common snail during the acquisition of sensitization.

Journal: Neuroscience and behavioral physiology 20050201

Title: Structural characterization of methionine and leucine enkephalins by hydrogen/deuterium exchange and electrospray ionization tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20050101

Title: Nucleocytoplasmic distribution of opioid growth factor and its receptor in tongue epithelium.

Journal: The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology 20050101

Title: Met-enkephalin modulation of age-related changes in red cell antioxidant status.

Journal: Physiological research 20050101

Title: delta-opioid receptor-mediated actions on rostral ventromedial medulla neurons.

Journal: Neuroscience 20050101

Title: Mu-opioid-mediated inhibition of glutamate synaptic transmission in rat central amygdala neurons.

Journal: Neuroscience 20050101

Title: [Spatial structure of BAM-12P dodecapeptide and its analogues].

Journal: Bioorganicheskaia khimiia 20050101

Title: In vitro modulation of cytokine expression by enkephalin-derived peptides.

Journal: Neuroimmunomodulation 20050101

Title: Distribution of methionine and leucine enkephalin neurons within the social behavior circuitry of the male Syrian hamster brain.

Journal: Brain research 20041224

Title: Effects of intrathecal BAM22 on noxious stimulus-evoked c-fos expression in the rat spinal dorsal horn.

Journal: Brain research 20041203

Title: Grafts of immortalized chromaffin cells bio-engineered to improve met-enkephalin release also reduce formalin-evoked c-fos expression in rat spinal cord.

Journal: Neuroscience letters 20041103

Title: Maternal separation alters maternal care, but has minor effects on behavior and brain opioid peptides in adult offspring.

Journal: Developmental psychobiology 20041101

Title: Met-enkephalin modulates resistance to oxidative stress in mouse brain.

Journal: Neuropeptides 20041001

Title: Chronic morphine treatment reduces recovery from opioid desensitization.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040901

Title: The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat.

Journal: European journal of pharmacology 20040616

Title: Non-opioid actions of opioid peptides.

Journal: Life sciences 20040604

Title: Opioid growth factor (OGF) inhibits anchorage-independent growth in human cancer cells.

Journal: International journal of oncology 20040601

Title: Chemoarchitectonic subdivisions of the songbird septum and a comparative overview of septum chemical anatomy in jawed vertebrates.

Journal: The Journal of comparative neurology 20040531

Title: Relative contribution of endogenous opioids to myocardial ischemic tolerance.

Journal: The Journal of surgical research 20040501

Title: Influence of ethanol dependence and methionine enkephalin antisense on serum endomorphin-1 and methionine enkephalin levels.

Journal: Alcoholism, clinical and experimental research 20040501

Title: Intrathecal xenogeneic chromaffin cell grafts reduce nociceptive behavior in a rodent tonic pain model.

Journal: Experimental neurology 20040401

Title: Differential regulation of hippocampal progenitor proliferation by opioid receptor antagonists in running and non-running spontaneously hypertensive rats.

Journal: The European journal of neuroscience 20040401

Title: Metabolism and absorption enhancement of methionine enkephalin in human nasal epithelium.

Journal: Peptides 20040401

Title: Effect of estradiol on expression and activation of Akt protein in rat hypothalamus exposed to chronic [D-Met2, Pro5]-enkephalinamide treatment.

Journal: Steroids 20040401

Title: PEACH 4 with ABINIT-MP: a general platform for classical and quantum simulations of biological molecules.

Journal: Computational biology and chemistry 20040401

Title: Neuropeptide Y-mediated inhibition of proopiomelanocortin neurons in the arcuate nucleus shows enhanced desensitization in ob/ob mice.

Journal: Neuron 20040304

Title: Neuropathological evaluation of the diencephalon, basal ganglia and upper brainstem in alobar holoprosencephaly.

Journal: Acta neuropathologica 20040301

Title: A multidimensional 1H NMR investigation of the conformation of methionine-enkephalin in fast-tumbling bicelles.

Journal: Biophysical journal 20040301

Title: Endogenous peripheral antinociception in early inflammation is not limited by the number of opioid-containing leukocytes but by opioid receptor expression.

Journal: Pain 20040301

Title: Gene expression of OGFr in the developing and adult rat brain and cerebellum.

Journal: Brain research bulletin 20040301

Title: Dual effects of intrathecal BAM22 on nociceptive responses in acute and persistent pain--potential function of a novel receptor.

Journal: British journal of pharmacology 20040201

Title: Insights on the interaction of met-enkephalin with negatively charged membranes--an infrared and solid-state NMR spectroscopic study.

Journal: Chemistry and physics of lipids 20040201

Title: Responses of plasma proenkephalin peptide F in rats following 14 days of spaceflight.

Journal: Aviation, space, and environmental medicine 20040201

Title: Opioid growth factor inhibition of a human squamous cell carcinoma of the head and neck in nude mice: dependency on the route of administration.

Journal: International journal of oncology 20040101

Title: Immunocytochemical distribution of Met-enkephalin-Arg6-Gly7-Leu8 (Met-8) in the auditory system of the rat.

Journal: Hearing research 20040101

Title: Signaling pathway involved in methionine enkephalin-promoted survival of lymphocytes infected by simian immunodeficiency virus in the early stage in vitro.

Journal: International immunopharmacology 20040101

Title: Production and characterization of antibodies for the specific determination of the opioid peptide Met5-Enkephalin-Arg6-Phe7.

Journal: Scandinavian journal of clinical and laboratory investigation 20040101

Title: Modulation of delayed-type hypersensitivity responses in hairless guinea pigs by peptides derived from enkephalin.

Journal: Neuroimmunomodulation 20040101

Title: Cloning of prodynorphin cDNAs from the brain of Australian and African lungfish: implications for the evolution of the prodynorphin gene.

Journal: Neuroendocrinology 20040101

Title: Evidence for the involvement of an opioid system in sciatic nerve of Rana ridibunda.

Journal: Neuropeptides 20040101

Title: An immunocytochemical mapping of methionine-enkephalin-Arg(6)-Gly(7)-Leu(8) in the human brainstem.

Journal: Neuroscience 20040101

Title: Methionine-enkephalin stimulates hydrogen peroxide and nitric oxide production in rat peritoneal macrophages: interaction of mu, delta and kappa opioid receptors.

Journal: Neuroimmunomodulation 20040101

Title: Cerebrospinal fluid levels of opioid peptides in fibromyalgia and chronic low back pain.

Journal: BMC musculoskeletal disorders 20040101

Title: Sustained exogenous administration of Met5-enkephalin protects against infarction in vivo.

Journal: American journal of physiology. Heart and circulatory physiology 20031201

Title: Stress applied during primary immunization affects the secondary humoral immune response in the rat: involvement of opioid peptides.

Journal: Stress (Amsterdam, Netherlands) 20031201

Title: Effects of chronic ethanol on brain and serum level of methionine enkephalin.

Journal: Peptides 20031201

Title: Cardiac enkephalins attenuate vagal bradycardia: interactions with NOS-1-cGMP systems in canine sinoatrial node.

Journal: American journal of physiology. Heart and circulatory physiology 20031101

Title: Comparison of epigenetic and genetic alterations in mucinous cystic neoplasm and serous microcystic adenoma of pancreas.

Journal: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20031101

Title: An opioid basis for early-phase isoflurane-induced hypotension in rats.

Journal: Life sciences 20031003

Title: Effects of endogenous and synthetic opioid peptides on neutrophil function in vitro.

Journal: British journal of anaesthesia 20031001

Title: Opioid growth factor (OGF) inhibits the progression of human squamous cell carcinoma of the head and neck transplanted into nude mice.

Journal: Cancer letters 20030925

Title: The regulation of steroidogenesis by opioid peptides in porcine theca cells.

Journal: Animal reproduction science 20030915

Title: Activation of delta- and kappa-opioid receptors by opioid peptides protects cardiomyocytes via KATP channels.

Journal: American journal of physiology. Heart and circulatory physiology 20030901

Title: Close apposition of dynorphin-positive nerve fibres to lymphocytes in the liver suggests opioidergic neuroimmunomodulation.

Journal: Histochemistry and cell biology 20030901

Title: Bimodal delta-opioid receptors regulate vagal bradycardia in canine sinoatrial node.

Journal: American journal of physiology. Heart and circulatory physiology 20030901

Title: c-Fos and peptide immunoreactivities in the central extended amygdala of morphine-dependent rats after naloxone-precipitated withdrawal.

Journal: The European journal of neuroscience 20030901

Title: Aggression and the three opioid families (endorphins, enkephalins, and dynorphins) in mice.

Journal: Behavior genetics 20030901

Title: A genetic algorithm with conformational memories for structure prediction of polypeptides.

Journal: Journal of biomolecular structure & dynamics 20030801

Title: Opioid peptides modulate the response of neurons of the superficial laminae of the rat spinal dorsal horn to GABA.

Journal: Biochemical and biophysical research communications 20030801

Title: Effect of synthetic oligopeptides on osteoporosis.

Journal: Preparative biochemistry & biotechnology 20030801

Title: Different mechanisms of intrinsic pain inhibition in early and late inflammation.

Journal: Journal of neuroimmunology 20030801

Title: Interaction of the neuropeptide met-enkephalin with zwitterionic and negatively charged bicelles as viewed by 31P and 2H solid-state NMR.

Journal: Biophysical journal 20030701

Title: Effects and mechanisms of melatonin on immune responses in mice of different months.

Journal: Acta pharmacologica Sinica 20030701

Title: Effects of neurotransmitters on the chemokinesis and chemotaxis of MDA-MB-468 human breast carcinoma cells.

Journal: Breast cancer research and treatment 20030701

Title: Enkephalinergic involvement in substantia nigra in the modulation of hypothalamically-induced predatory attack behavior.

Journal: Indian journal of physiology and pharmacology 20030701

Title: Study of serum lipid profile changes in Met-enkephalin treated rats.

Journal: Indian journal of physiology and pharmacology 20030701

Title: Presence of opioid growth factor and its receptor in the normal dog, cat and horse cornea.

Journal: Veterinary ophthalmology 20030601

Title: Developmental changes in the inhibition of cultured rat uterine cell proliferation by opioid peptides.

Journal: Cell proliferation 20030601

Title: Uterus-innervating neurones in porcine inferior mesenteric ganglion: an immunohistochemical characteristic.

Journal: Anatomia, histologia, embryologia 20030601

Title: Anatomical relationship between enkephalin-containing neurones and caecum-projecting neurones in the chicken intestinal nerve.

Journal: Anatomia, histologia, embryologia 20030601

Title: Formation of dendritic spines in cultured striatal neurons depends on excitatory afferent activity.

Journal: The European journal of neuroscience 20030601

Title: Selective roles for the PC2 processing enzyme in the regulation of peptide neurotransmitter levels in brain and peripheral neuroendocrine tissues of PC2 deficient mice.

Journal: Neuropeptides 20030601

Title: Long-term effects of short and long periods of maternal separation on brain opioid peptide levels in male Wistar rats.

Journal: Neuropeptides 20030601

Title: The selective action of opioid peptides on excitability and the various sensory inputs of defensive behavior command neurons LPl1 and RPl1 of the common snail.

Journal: Neuroscience and behavioral physiology 20030601

Title: Cardiac enkephalins interrupt vagal bradycardia via delta 2-opioid receptors in sinoatrial node.

Journal: American journal of physiology. Heart and circulatory physiology 20030501

Title: Endogenous opioid peptides contribute to antinociceptive potency of intrathecal [Dmt1]DALDA.

Journal: The Journal of pharmacology and experimental therapeutics 20030501

Title: Purification and quantification of opioid peptides in bone and joint tissues--a methodological study in the rat.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20030501

Title: Methionine enkephalin suppresses metabolic activity of a leukemic cell line (NALM-1) and enhances CD10 expression.

Journal: International immunopharmacology 20030501

Title: Cellular actions of opioids on periaqueductal grey neurons from C57B16/J mice and mutant mice lacking MOR-1.

Journal: British journal of pharmacology 20030501

Title: Central D-Ala2-Met5-enkephalinamide mu/delta-opioid receptor activation reverses the anxiogenic-like properties of cholecystokinin on locomotor and rearing activity in CD-1 mice.

Journal: Brain research 20030425

Title: Central D-Ala2-Met5-enkephalinamide mu/delta-opioid receptor activation blocks behavioral sensitization to cholecystokinin in CD-1 mice.

Journal: Brain research 20030425

Title: Ca2+-independent protein kinase Cs mediate heterologous desensitization of leukocyte chemokine receptors by opioid receptors.

Journal: The Journal of biological chemistry 20030411

Title: An immunocytochemical mapping of methionine-enkephalin-Arg6-Gly7-Leu8 in the cat brainstem.

Journal: Anatomy and embryology 20030401

Title: Immunoelectron microscopic localization of the opioid growth factor receptor (OGFr) and OGF in the cornea.

Journal: Brain research 20030328

Title: Opioid modulation of taste responses in the nucleus of the solitary tract.

Journal: Brain research 20030307

Title: Opioid growth factor inhibits intimal hyperplasia in balloon-injured rat carotid artery.

Journal: Journal of vascular surgery 20030301

Title: Peptide separations and dissociation constants in nonaqueous capillary electrophoresis: comparison of methanol and aqueous buffers.

Journal: Electrophoresis 20030301

Title: A comparison between electrokinetic capillary chromatography and absorption spectroscopy for the analysis of peptide-micelle association by weak hydrophobic interactions.

Journal: Electrophoresis 20030301

Title: Influence of ovarian sex steroids on spinal methionine-enkephalin release: comparison with dynorphin reveals asymmetrical regulation.

Journal: The Journal of pharmacology and experimental therapeutics 20030201

Title: Hybrid global optimization algorithms for protein structure prediction: alternating hybrids.

Journal: Biophysical journal 20030201

Title: Up-regulation of methionine-enkephalin-like immunoreactivity by 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment in the forebrain of the Long-Evans rat.

Journal: Journal of chemical neuroanatomy 20030201

Title: Behavioral and neuroendocrine actions of the Met-enkephalin-related peptide MERF.

Journal: Hormones and behavior 20030201

Title: A new cytokine: the possible effect pathway of methionine enkephalin.

Journal: World journal of gastroenterology 20030115

Title: In vitro human plasma leucine(5)-enkephalin degradation is inhibited by a select number of drugs with the phenothiazine molecule in their chemical structure.

Journal: Pharmacology 20030101

Title: Enkephalin degradating enzymes in pheochromocytoma patients.

Journal: Oncology reports 20030101

Title: Modulation of peripheral endogenous opioid analgesia by central afferent blockade.

Journal: Anesthesiology 20030101

Title: Antinociceptive effect of calcitonin gene-related peptide in the central nucleus of amygdala: activating opioid receptors through amygdala-periaqueductal gray pathway.

Journal: Neuroscience 20030101

Title: [The role of neuropeptides in brain asymmetry].

Journal: Zhurnal evoliutsionnoi biokhimii i fiziologii 20030101

Title: Conformational sampling by self-organization.

Journal: Journal of chemical information and computer sciences 20030101

Title: Effect of exogenous opioid peptides on TNF-alpha-induced human neutrophil apoptosis in vitro.

Journal: Archivum immunologiae et therapiae experimentalis 20030101

Title: Inflammation-induced alternations in local and central Met-enkephalin in mice.

Journal: Polish journal of pharmacology 20030101

Title: Dynorphinergic GABA neurons are a target of both typical and atypical antipsychotic drugs in the nucleus accumbens shell, central amygdaloid nucleus and thalamic central medial nucleus.

Journal: Neuroscience 20030101

Title: Tetanus neurotoxin-insensitive vesicle-associated membrane protein localizes to a presynaptic membrane compartment in selected terminal subsets of the rat brain.

Journal: Neuroscience 20030101

Title: The probability distribution of side-chain conformations in [Leu] and [Met]enkephalin determines the potency and selectivity to mu and delta opiate receptors.

Journal: Biopolymers 20030101

Title: [Met-enkephalin plasma concentration and content in liver tissue in patients with primary biliary cirrhosis].

Journal: Przeglad lekarski 20030101

Title: [Selective involvement of opioids in mechanisms of synapse-specific plasticity in Helix lucorum snail during sensitization acquisition].

Journal: Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20030101

Title: [Comparative study of neurochemical compensation of brain dysfunctions in mammals].

Journal: Zhurnal evoliutsionnoi biokhimii i fiziologii 20030101

Title: Organization of the avian basal forebrain: chemical anatomy in the parrot (Melopsittacus undulatus).

Journal: The Journal of comparative neurology 20021223

Title: Dopaminergic system modulation of nociceptive response in long-term diabetic rats.

Journal: Pharmacology, biochemistry, and behavior 20021201

Title: Plasma levels of opioid peptides after sunbed exposures.

Journal: The British journal of dermatology 20021201

Title: Methionine-enkephalin and leucine-enkephalin increase interleukin-1 beta release in mixed glia cultures.

Journal: Neuropeptides 20021201

Title: Effect of cerebral ventricles perfusion with morphiceptin and Met-enkephalin on trigemino-hypoglossal reflex in rats.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20021201

Title: Met-enkephalin modulates lipid peroxidation and total sialic acid level in CBA mice in age- and sex-dependent manners.

Journal: Experimental gerontology 20021201

Title: [Opioid mechanism of regulation of the autonomic and motor functions in rabbits].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20021201

Title: Correlated morphological and chemical phenotyping in myenteric type V neurons of porcine ileum.

Journal: The Journal of comparative neurology 20021104

Title: [Met5]enkephalin-Arg-Gly-Leu-induced antinociception is greatly increased by peptidase inhibitors.

Journal: European journal of pharmacology 20021018

Title: Naltrexone, an opioid antagonist, facilitates reepithelialization of the cornea in diabetic rat.

Journal: Diabetes 20021001

Title: Integration of solid-phase extraction membranes for sample multiplexing: application to rapid protein identification from gel-isolated protein extracts.

Journal: Electrophoresis 20021001

Title: Different effects of methionine-enkephalin on paw edema in two inbred rat strains.

Journal: Peptides 20020901

Title: Met-enkephalin immunoreactive neurons recruited by acute stress are innervated by axon terminals immunopositive for tyrosine hydroxylase and dopamine-alpha-hydroxylase in the anterolateral division of bed nuclei of the stria terminalis in the rat.

Journal: The European journal of neuroscience 20020901

Title: Effects and mechanisms of melatonin on inflammatory and immune responses of adjuvant arthritis rat.

Journal: International immunopharmacology 20020901

Title: Conditioned opioid withdrawal decreases nociceptin/orphanin FQ levels in the frontal cortex and olfactory tubercle.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20020801

Title: GABA-opioid interactions in the globus pallidus: [D-Ala2]-Met-enkephalinamide attenuates potassium-evoked GABA release after nigrostriatal lesion.

Journal: Journal of neurochemistry 20020801

Title: Effect of synthetic oligopeptides on osteoporosis.

Journal: Preparative biochemistry & biotechnology 20020801

Title: Influence of opioid peptides on human neutrophil apoptosis and activation in vitro.

Journal: Mediators of inflammation 20020801

Title: Control of non-adrenergic non-cholinergic reflex motor responses in circular muscle of guinea-pig small intestine by Met-enkephalin.

Journal: Autonomic & autacoid pharmacology 20020801

Title: Induction of antinociception and increased met-enkephalin plasma levels by cyclosporine and morphine in rats: implications of the combined use of cyclosporine and morphine and acute posttransplant neuropsychosis.

Journal: The Journal of surgical research 20020701

Title: Inhibitory effects of opioids on voltage-dependent Ca(2+) channels and catecholamine secretion in cultured porcine adrenal chromaffin cells.

Journal: Brain research 20020628

Title: Striatal neurochemical changes in transgenic models of Huntington's disease.

Journal: Journal of neuroscience research 20020615

Title: G-protein-gated potassium channels containing Kir3.2 and Kir3.3 subunits mediate the acute inhibitory effects of opioids on locus ceruleus neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020601

Title: Met-enkephalin and preproenkephalin mRNA changes in the striatum of the nicotine abstinence mouse.

Journal: Neuroscience letters 20020531

Title: Potentiation of the excitatory action of NMDA in ventrolateral periaqueductal gray by the mu-opioid receptor agonist, DAMGO.

Journal: Brain research 20020510

Title: Palladium(II) complexes, as synthetic peptidases, regioselectively cleave the second peptide bond 'upstream' from methionine and histidine side chains.

Journal: Journal of the American Chemical Society 20020501

Title: beta-Endorphin modulation of pressor response to hyperventilation in hypertensive patients.

Journal: Peptides 20020501

Title: Evidence for changes in brain enkephalin contents associated to male rat sexual activity.

Journal: Behavioural brain research 20020401

Title: Long time dynamics of Met-enkephalin: comparison of explicit and implicit solvent models.

Journal: Biophysical journal 20020401

Title: Hepatic Met-enkephalin immunoreactivity is enhanced in primary biliary cirrhosis.

Journal: Liver 20020401

Title: [Implication of the neuropeptides methionine enkephalin, neurotensin and somatostatin of the caudal trigeminal nucleus in the experimental migraine].

Journal: Revista de neurologia 20020401

Title: Occurrence, co-occurrence and topographic distribution of choline acetyl transferase, Met-enkephalin and neurotensin in the stellate ganglion of the cat.

Journal: Synapse (New York, N.Y.) 20020301

Title: Endomorphins, Met-enkephalin, Tyr-MIF-1, and the P-glycoprotein efflux system.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020301

Title: Monte Carlo sampling algorithm for searching a scale-transformed energy space of polypeptides.

Journal: Journal of computational chemistry 20020301

Title: Effect of tianeptine and fluoxetine on the levels of Met-enkephalin and mRNA encoding proenkephalin in the rat.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20020301

Title: Effect of synthetic beta-endorphin-like peptide immunorphin on human T lymphocytes.

Journal: Biochemistry. Biokhimiia 20020301

Title: Enkephalinergic control of the secretory activity of neurons producing stereoisomers of crustacean hyperglycemic hormone in the eyestalk of the crayfish Orconectes limosus.

Journal: The Journal of comparative neurology 20020225

Title: Global optimization by energy landscape paving.

Journal: Physical review letters 20020211

Title: Structure of Met-enkephalin in explicit aqueous solution using replica exchange molecular dynamics.

Journal: Proteins 20020201

Title: The biology of the opioid growth factor receptor (OGFr).

Journal: Brain research. Brain research reviews 20020201

Title: Alteration in endogenous opioid systems due to chronic inflammatory pain conditions.

Journal: European journal of pharmacology 20020125

Title: Evolutionary significance of different neurochemical organisation of the internal and external regions of auditory centres in the reptilian brain: an immunocytochemical and reduced NADPH-diaphorase histochemical study in turtles.

Journal: Brain research 20020118

Title: Chronic exposure to the opioid growth factor, [Met5]-enkephalin, during pregnancy: maternal and preweaning effects.

Journal: Pharmacology, biochemistry, and behavior 20020101

Title: [Selectivity of opioid peptide effects on excitability and various sensory inputs in LPl1 and PPl1 command neurons participating in defensive behavior of the snail Helix lucorum].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20020101

Title: Uterus-innervating neurones of paracervical ganglion in the pig: immunohistochemical characteristics.

Journal: Folia morphologica 20020101

Title: Consequences of intrauterine growth restriction on ventilatory and thermoregulatory responses to asphyxia and hypercapnia in the newborn guinea-pig.

Journal: Reproduction, fertility, and development 20020101

Title: [Neurochemical organization of the turtle pretectum: immunohistochemical study. Comparative analysis].

Journal: Zhurnal evoliutsionnoi biokhimii i fiziologii 20020101

Title: Transient arterial occlusion raises enkephalin in the canine sinoatrial node and improves vagal bradycardia.

Journal: Autonomic neuroscience : basic & clinical 20011210

Title: Release of [Met5]enkephalin from the spinal cord by intraventricularly administered endomorphin-2, but not endomorphin-1 in the anesthetized rat.

Journal: Neuroscience letters 20011204

Title: Reduced expression of neuropeptides can be related to respiratory disturbances in Rett syndrome.

Journal: Brain & development 20011201

Title: Effects of opioid receptor activation on cardiovascular responses and extracellular monoamines within the rostral ventrolateral medulla during static contraction of skeletal muscle.

Journal: Neuroscience research 20011201

Title: On-line preconcentration in capillary electrochromatography using a porous monolith together with solvent gradient and sample stacking.

Journal: Analytical chemistry 20011115

Title: The neuropeptide FF analogue, 1DMe, acts as a functional opioid autoreceptor antagonist in the rat spinal cord.

Journal: European journal of pharmacology 20011102

Title: Detection of nonderivatized peptides in capillary electrophoresis using quenched phosphorescence.

Journal: Analytical chemistry 20011101

Title: Suprachiasmatic nucleus in the mouse: retinal innervation, intrinsic organization and efferent projections.

Journal: Brain research 20011019

Title: The effect of methionine-enkephalin on nitric oxide release in mice is age and gender related.

Journal: Pharmacological research 20011001

Title: Endorphin and enkephalin ameliorate excessive synovial cell functions in patients with rheumatoid arthritis.

Journal: The Journal of rheumatology 20011001

Title: Delta opioid receptors inhibit vagal bradycardia in the sinoatrial node.

Journal: Journal of cardiovascular pharmacology and therapeutics 20011001

Title: Differential antinociceptive effects induced by intrathecally administered endomorphin-1 and endomorphin-2 in the mouse.

Journal: European journal of pharmacology 20010921

Title: Methionine-enkephalin-and Dynorphin A-release from immune cells and control of inflammatory pain.

Journal: Pain 20010901

Title: Opioid and GABA receptors involved in mediation and modulation of tonic and stimulus-evoked inhibition of a spinal reflex in the decerebrated and spinalized rabbit.

Journal: Neuropharmacology 20010901

Title: Naloxone blocks transferred preconditioning in isolated rabbit hearts.

Journal: Journal of molecular and cellular cardiology 20010901

Title: Effects of beta-endorphin and met-enkephalin on platelet activity.

Journal: American journal of hematology 20010901

Title: Methionine-enkephalin induces hyperglycemia through eyestalk hormones in the estuarine crab Scylla serrata.

Journal: The Biological bulletin 20010801

Title: Pre- and postsynaptic inhibition by nociceptin in guinea pig small intestinal myenteric plexus in vitro.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20010701

Title: Colocalization of GABA, enkephalin and neuropeptide Y in the tectum of the green frog Rana esculenta.

Journal: Peptides 20010701

Title: Met-enkephalin levels during PTCA-induced myocardial ischemia.

Journal: Peptides 20010701

Title: Evidence for a hyperglycemic effect of methionine-enkephalin in the prawns Penaeus indicus and Metapenaeus monocerus.

Journal: General and comparative endocrinology 20010701

Title: Temporal change of hippocampal enkephalin and dynorphin mRNA following trimethyltin intoxication in rats: effect of anticonvulsant.

Journal: Neuroscience letters 20010629

Title: Unique responses of limbic met-enkephalin systems to low and high doses of methamphetamine.

Journal: Brain research 20010629

Title: NO synthase inhibitors reduce opioid desensitization in rat locus coeruleus neurons in vitro.

Journal: Neuroreport 20010613

Title: Antisera against endogenous opioids increase the nocifensive response to formalin: demonstration of inhibitory beta-endorphinergic control.

Journal: European journal of pharmacology 20010601

Title: Transplacental transfer of the opioid growth factor, [Met(5)]-enkephalin, in rats.

Journal: Brain research bulletin 20010601

Title: [Inhibition of ATP-activated current by met-Enk in isolated DRG neurons of the rat].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20010601

Title: MEK inhibits secretin release and pancreatic secretion: roles of secretin-releasing peptide and somatostatin.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20010501

Title: Evidence that nitric oxide- and opioid-containing interneurons innervate vessels in the dorsal horn of the spinal cord of rats.

Journal: The Journal of physiology 20010501

Title: Delta9-tetrahydrocannabinol releases and facilitates the effects of endogenous enkephalins: reduction in morphine withdrawal syndrome without change in rewarding effect.

Journal: The European journal of neuroscience 20010501

Title: Effects of intracerebroventricularly administered chimeric peptide of metenkephalin and FMRFa--[D-Ala2]YFa-on antinociception and its modulation in mice.

Journal: Brain research bulletin 20010501

Title: Involvement of pro-enkephalin-derived peptides in immunity.

Journal: Developmental and comparative immunology 20010401

Title: Subcutaneous formalin enhances outflow of met-enkephalin- and cholecystokinin-like materials in the rat nucleus accumbens.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010401

Title: Axon terminals containing CGRP-immunoreactivity form synapses with CRF- and Met-enkephalin-immunopositive neurons in the laterodorsal division of the bed nucleus of the stria terminalis in the rat.

Journal: Brain research 20010302

Title: Anti-mitogenic action of opioid peptides on epidermal growth factor-stimulated uterine cells.

Journal: European journal of pharmacology 20010302

Title: Withdrawal from alcohol in withdrawal seizure-prone and -resistant mice: evidence for enkephalin resistance.

Journal: Pharmacology, biochemistry, and behavior 20010301

Title: Neutrophil neutral endopeptidase variation and its regulation by opioid peptides.

Journal: International immunopharmacology 20010301

Title: Local opiate receptors in the sinoatrial node moderate vagal bradycardia.

Journal: Autonomic neuroscience : basic & clinical 20010220

Title: Contrasting responses by basal ganglia met-enkephalin systems to low and high doses of methamphetamine in a rat model.

Journal: Journal of neurochemistry 20010201

Title: Absence of spinal response to extracorporeal shock waves on the endogenous opioid systems in the rat.

Journal: Ultrasound in medicine & biology 20010201

Title: Direct actions of cannabinoids on synaptic transmission in the nucleus accumbens: a comparison with opioids.

Journal: Journal of neurophysiology 20010101

Title: [Non-adrenergic mechanisms of inhibition of the contractile activity of the cat small intestine by histamine, bradykinin, and met-enkephalin].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20010101

Title: [The neuropeptide compensation for impared brain functions in the ascending row of mammals: interaction between the nervous and immune systems].

Journal: Fiziologiia cheloveka 20010101

Title: Met-enkephalin is preferentially transported into the peripheral processes of primary afferent fibres in both control and HSV1-driven proenkephalin A overexpressing rats.

Journal: Neuroscience 20010101

Title: Characterization of kappa and delta opioid receptors in isolated organs by using type/subtype selective agonists and antagonists.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20010101

Title: Effects of neonatal handling on nociceptin/orphanin FQ and opioid peptide levels in female rats.

Journal: Pharmacology, biochemistry, and behavior 20010101

Title: An apparatus to assay opioid activity in the infused lumen of the intact isolated guinea pig ileum.

Journal: Journal of pharmacological and toxicological methods 20010101

Title: On the mode of action of methionine enkephalin, FK 33-824 and naloxone in regulating the hemolymph glucose level in the fresh water field crab Oziotelphusa senex senex.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101

Title: Protection of mice from malaria after co-administration of recombinant mouse granulocyte-macrophage colony- stimulating factor and methionine-enkephalin.

Journal: European cytokine network 20010101

Title: Cytoprotective effects of met-enkephalin and alpha-MSH on ethanol induced gastric lesions in rats.

Journal: Journal of physiology, Paris 20010101

Title: Modulation of fas/fasL in a murine retroviral infection by AZT and methionine enkephalin.

Journal: Advances in experimental medicine and biology 20010101

Title: Ultrastructural co-localization of methionine enkephalin and neurotensin in the synapse of the cat stellate ganglia.

Journal: Proceedings of the Western Pharmacology Society 20010101

Title: The role of met-enkephalin in silent myocardial ischemia in diabetic patients.

Journal: Journal of medicine 20010101

Title: Receptor binding and G-protein activation by new Met5-enkephalin-Arg6-Phe7 derived peptides.

Journal: Life sciences 20000218

Title: Delta-opioid receptor antagonist inhibits immunomodulation by Met-enkephalin analogs.

Journal: Neuroimmunomodulation 19990101

Title: Oxytocin modulates glutamatergic synaptic transmission between cultured neonatal spinal cord dorsal horn neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 19980401

Title: Conformational analysis of [Met5]-enkephalin: solvation and ionization considerations.

Journal: Journal of computer-aided molecular design 19980301

Title: The mu-opioid receptor antagonist D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP) [but not D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (CTAP)] produces a nonopioid receptor-mediated increase in K+ conductance of rat locus ceruleus neurons.

Journal: Molecular pharmacology 19960901

Title: The cloned mu, delta and kappa receptors and their endogenous ligands: evidence for two opioid peptide recognition cores.

Journal: Brain research 19951127

Title: Isolation and characterization of opioid peptides in the avian brain.

Journal: The Journal of experimental zoology 19951001

Title: An endogenous aminoenkephalinase inhibitor: purification and characterization of Arg0-Met5-enkephalin from bovine striatum.

Journal: Journal of neurochemistry 19941101

Title: Valproic acid-induced rapid changes of met-enkephalin levels in rat brain. Probable association with abstinence behavior and anticonvulsant activity.

Journal: Neuropeptides 19940901

Title: Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.

Journal: Molecular pharmacology 19940201

Title: Metabolism and transport of the pentapeptide metkephamid by brush-border membrane vesicles of rat intestine.

Journal: The Journal of pharmacy and pharmacology 19940101

Title: Cloning and pharmacological characterization of a rat kappa opioid receptor.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19931101

Title: Kinetic parameters of antagonism by the delta opioid receptor selective peptide antagonist Boc-Tyr-Pro-Gly-Phe-Leu-Thr against selective and non-selective agonists in the mouse vas deferens.

Journal: Neuropeptides 19930801

Title: Cloning and functional comparison of kappa and delta opioid receptors from mouse brain.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19930715

Title: Enkephalin antisense peptides: design, synthesis, and biological activity.

Journal: Pharmaceutical research 19930501

Title: Comparative action of Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2 analogs on intestinal motility and nociception in rats.

Journal: The Journal of pharmacology and experimental therapeutics 19930401

Title: In vivo modulation of gastrointestinal motor activity by Met-enkephalin, morphine and enkephalin analogs in chickens.

Journal: Regulatory peptides 19930305

Title: [Approach to studying the structure-activity relationship of native peptides. I. Structural organization of the opioid peptide Tyr-Glu-Gly-Phe-Met-Arg-Gly-Leu and its artificial analogs].

Journal: Bioorganicheskaia khimiia 19921201

Title: Feedback inhibition of met-enkephalin release from the rat spinal cord in vivo.

Journal: Synapse (New York, N.Y.) 19920501

Title: Opioid control of the in vitro release of cholecystokinin-like material from the rat substantia nigra.

Journal: Journal of neurochemistry 19920301

Title: A novel opioid structure which accepts protonated as well as non-protonated nitrogen: a family of pure, delta receptor selective antagonists.

Journal: Life sciences 19920101

Title: [The role of the opiate mechanisms of the hippocampus and substantia nigra in the behavioral and convulsive disorders in picrotoxin-induced kindling].

Journal: Biulleten' eksperimental'noi biologii i meditsiny 19910301

Title: Single potassium channels opened by opioids in rat locus ceruleus neurons.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19890501

Title: Antidiarrheal properties of supraspinal mu and delta and peripheral mu, delta and kappa opioid receptors: inhibition of diarrhea without constipation.

Journal: The Journal of pharmacology and experimental therapeutics 19890401

Title: Monoclonal antibody against a peptide specified by [Met]-enkephalin complementary RNA recognizes the delta-class opioid receptor.

Journal: Immunology letters 19890201

Title: Purification and assay of opioid activity of low molecular weight enkephalin-immunoreactive peptides generated by peptic digestion of rat plasma proteins.

Journal: Neuropeptides 19890101

Title: Selectivity of various opioid peptides towards delta-, kappa; and mu-opioid receptors mediating presynaptic inhibition of neurotransmitter release in the brain.

Journal: Neuropeptides 19890101

Title: Effect of enkephalin analogues Tyr-D-Ala-Gly-Phe-Cys(Et) and Tyr-D-Ala-Gly-Phe-Cys(Bu) on prolactin and growth hormone release in rats.

Journal: Endocrinologia experimentalis 19881201

Title: Development of conformationally constrained linear peptides exhibiting a high affinity and pronounced selectivity for delta opioid receptors.

Journal: Journal of medicinal chemistry 19881001

Title: Inhibition of exocrine pancreatic secretion by opiates is mediated by suppression of cholinergic transmission: characterization of receptor subtypes.

Journal: The Journal of pharmacology and experimental therapeutics 19880701

Title: [D-Met2,Pro5] enkephalin [N1.5-beta-D-glucopyranosyl] amide: a glycosylpeptide with high antinociceptive activity.

Journal: International journal of peptide and protein research 19880501

Title: [3H][D-Ser2(O-tert-butyl),Leu5]enkephalyl-Thr6 and [D-Ser2(O-tert-butyl),Leu5]enkephalyl-Thr6(O-tert-butyl). Two new enkephalin analogs with both a good selectivity and a high affinity toward delta-opioid binding sites.

Journal: The Journal of biological chemistry 19880325

Title: Conformational analysis of possible biologically active (receptor-bound) conformations of peptides derived from cholecystokinin, cerulein and little gastrin and the opiate peptide, Met-enkephalin.

Journal: Peptides 19880101

Title: [Biosynthesis of opioid peptides].

Journal: Annales d'endocrinologie 19880101

Title: Potentiation of enkephalin action by peptidase inhibitors in rat locus ceruleus in vitro.

Journal: The Journal of pharmacology and experimental therapeutics 19871001

Title: An approach to the multiple-minima problem in protein folding by relaxing dimensionality. Tests on enkephalin.

Journal: Journal of molecular biology 19870805

Title: Mu and delta receptors belong to a family of receptors that are coupled to potassium channels.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19870801

Title: The effects of cortical ablation on multiple unit activity in the striatum following dexamphetamine.

Journal: Neuropharmacology 19870801

Title: An acid-labile anchoring linkage for solid-phase synthesis of C-terminal peptide amides under mild conditions.

Journal: International journal of peptide and protein research 19870801

Title: Enkephalins in the rat pituitary gland: immunohistochemical and biochemical observations.

Journal: Endocrinology 19870701

Title: Mu opioid receptor involvement in enkephalin activation of dopamine neurons in the ventral tegmental area.

Journal: The Journal of pharmacology and experimental therapeutics 19870401

Title: Audiogenic seizures during ethanol withdrawal can be blocked by a delta opioid agonist.

Journal: Drug and alcohol dependence 19861201

Title: Kinetics of four 11C-labelled enkephalin peptides in the brain, pituitary and plasma of rhesus monkeys.

Journal: Regulatory peptides 19861201

Title: Steady-state level and turnover rate of the tripeptide Tyr-Gly-Gly as indexes of striatal enkephalin release in vivo and their reduction during pentobarbital anesthesia.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19860801

Title: Enhancement of the generation of cytotoxic T cells by endogenous opiates.

Journal: Journal of neuroimmunology 19860701

Title: Pharmacological properties of acetorphan, a parenterally active 'enkephalinase' inhibitor.

Journal: The Journal of pharmacology and experimental therapeutics 19860601

Title: Metorphamide levels in chromaffin cells increase after treatment with reserpine.

Journal: Journal of neurochemistry 19860501

Title: Specificity of the opioid affinity reagent, DALECK, in a set of isolated tissue assay systems.

Journal: Neuropeptides 19860101

Title: Angiotensin-converting enzyme inhibitors potentiate the analgesic activity of [Met]-enkephalin-Arg6-Phe7 by inhibiting its degradation in mouse brain.

Journal: Molecular pharmacology 19851201

Title: Receptors for opioid peptides in the guinea-pig ileum.

Journal: The Journal of pharmacology and experimental therapeutics 19851101

Title: Modulation of striatal enkephalinergic neurons by antipsychotic drugs.

Journal: Federation proceedings 19850601

Title: Proteolytic conversion of [Met]enkephalin-Arg6-Gly7-Leu8 by brain synaptic membranes. Characterization of formed peptides and mechanism of proteolysis.

Journal: The Journal of biological chemistry 19850310

Title: Cardiovascular properties of metkephamid, a delta opioid receptor agonist, in man.

Journal: Clinical science (London, England : 1979) 19850201

Title: Cardiovascular effects of intraventricular injection of FMRFamide, Met-enkephalin and their common analogues in the rat.

Journal: Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 19850101

Title: Catalepsy, hypermotility, increase of striatal acetylcholine release induced by morphine and Met-enkephalin as affected by prolonged hydrocortisone and ACTH treatment.

Journal: Polish journal of pharmacology and pharmacy 19850101

Title: A new immunological approach to the detection and the quantitation of the Met5-enkephalin precursors in rat brain.

Journal: Neuropeptides 19840901

Title: Alternative modes of enkephalin biosynthesis regulation by reserpine and cyclic AMP in cultured chromaffin cells.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19840701

Title: Nonspecific convulsions are induced by morphine but not D-Ala2-methionine-enkephalinamide at cortical sites.

Journal: Brain research 19840507

Title: Sensitivity to morphine-evoked bradycardia in rats is modified by dynorphin (1-13), Leu- and Met-enkephalin.

Journal: The Journal of pharmacology and experimental therapeutics 19840501

Title: Opioid-induced epileptogenic phenomena: anatomical, behavioral, and electroencephalographic features.

Journal: Annals of neurology 19840401

Title: Effects of enkephalins and their analogs on gastric secretion.

Journal: Neuroscience and behavioral physiology 19840101

Title: Metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19831201

Title: Specific polyclonal antibodies to the carboxyl terminus of [Met]enkephalin-Arg6-Gly7-Leu8.

Journal: Archives of biochemistry and biophysics 19830901

Title: Distribution of enkephalin-related peptides in rat brain: immunohistochemical studies using antisera to met-enkephalin and met-enkephalin Arg6Phe7.

Journal: Neuroscience 19830701

Title: Tolerance to morphine bradycardia in the rat.

Journal: The Journal of pharmacology and experimental therapeutics 19830701

Title: Interaction of naloxone with mu- and delta-opioid agonists on the respiration of rats.

Journal: European journal of pharmacology 19830218

Title: Local and distal effects induced by unilateral striatal application of opiates in the absence or in the presence of naloxone on the release of dopamine in both caudate nuclei and substantiae nigrae of the cat.

Journal: Brain research 19830110

Title: Blood pressure elevation in rats by peripheral administration of Tyr-Gly-Gly-Phe-Met-Arg-Phe and the invertebrate neuropeptide, Phe-Met-Arg-Phe-NH2.

Journal: Life sciences 19821206

Title: Modulation of dopamine release in rat striatal slices by delta opiate agonists.

Journal: The Journal of pharmacology and experimental therapeutics 19820801

Title: Mammalian neuronal actions of FMRFamide and the structurally related opioid Met-enkephalin-Arg6-Phe7.

Journal: Nature 19820715

Title: Partial characterization of the mRNA that codes for enkephalins in bovine adrenal medulla and human pheochromocytoma.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19820101

Title: Proteolytic specificity of hemorrhage toxin a isolated from western diamondback rattlesnake (Crotalus atrox) venom.

Journal: Biochemistry 19811124

Title: Evidence of the preferential involvement of mu receptors in analgesia using enkephalins highly selective for peripheral mu or delta receptors.

Journal: Journal of medicinal chemistry 19811001

Title: Indication for central vagal endorphinergic control of heart rate in dogs.

Journal: European journal of pharmacology 19810522

Title: Preliminary analysis of 1H and 13C spectral and relaxation behavior in methionine-enkephalin.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19760801

Title: Morphine-like peptides in mammalian brain: isolation, structure elucidation, and interactions with the opiate receptor.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19760701

Title: Identification of two related pentapeptides from the brain with potent opiate agonist activity.

Journal: Nature 19751218

Title: Zhao D, et al. Methionine enkephalin, its role in immunoregulation and cancer therapy. Int Immunopharmacol. 2016 Feb 23. pii: S1567-5769(16)30050-9.

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Tags:58569-55-4 Molecular Formula|58569-55-4 MDL|58569-55-4 SMILES|58569-55-4 Met-enkephalin
Catalog No.: AA00E8N8
58569-55-4,MFCD00076415
58569-55-4 | Met-enkephalin
Pack Size: 250mg
Purity: 98%
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$643.00 $450.00
Pack Size: 1g
Purity: 98%
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Purity: 98%
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Technical Information
Catalog Number: AA00E8N8
Chemical Name: Met-enkephalin
CAS Number: 58569-55-4
Molecular Formula: C27H35N5O7S
Molecular Weight: 573.6611
MDL Number: MFCD00076415
SMILES: CSCC[C@@H](C(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(cc1)O)N
Properties
Complexity: 847  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 3  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 40  
Hydrogen Bond Acceptor Count: 9  
Hydrogen Bond Donor Count: 7  
Isotope Atom Count: 0  
Rotatable Bond Count: 16  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: -2.1  
Literature fold

Title: Synthesis of Met-enkephalin by solution-phase peptide synthesis methodology utilizing para-toluene sulfonic acid as N-terminal masking of l-methionine amino acid.

Journal: Chemical biology & drug design20161201

Title: Orally active opioid μ/δ dual agonist MGM-16, a derivative of the indole alkaloid mitragynine, exhibits potent antiallodynic effect on neuropathic pain in mice.

Journal: The Journal of pharmacology and experimental therapeutics20140301

Title: Methionine residue acts as a prooxidant in the •OH-induced oxidation of enkephalins.

Journal: The journal of physical chemistry. B20121018

Title: Opioids inhibit visceral afferent activation of catecholamine neurons in the solitary tract nucleus.

Journal: Neuroscience20121011

Title: Opiorphin highly improves the specific binding and affinity of MERF and MEGY to rat brain opioid receptors.

Journal: Regulatory peptides20121010

Title: Induction on differentiation and modulation of bone marrow progenitor of dendritic cell by methionine enkephalin (MENK).

Journal: Cancer immunology, immunotherapy : CII20121001

Title: Macrophage polarization induced by neuropeptide methionine enkephalin (MENK) promotes tumoricidal responses.

Journal: Cancer immunology, immunotherapy : CII20121001

Title: Repetitive electroacupuncture causes prolonged increased met-enkephalin expression in the rVLM of conscious rats.

Journal: Autonomic neuroscience : basic & clinical20120925

Title: The opioid growth factor-opioid growth factor receptor axis: homeostatic regulator of cell proliferation and its implications for health and disease.

Journal: Biochemical pharmacology20120915

Title: Disturbances in behavior and cortical enkephalin gene expression during the anticipation of ethanol in rats characterized as high drinkers.

Journal: Alcohol (Fayetteville, N.Y.)20120901

Title: Autocrine regulation of human sperm motility by the met-enkephalin opioid peptide.

Journal: Fertility and sterility20120901

Title: Supraspinal peroxynitrite modulates pain signaling by suppressing the endogenous opioid pathway.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20120808

Title: Cathepsin H functions as an aminopeptidase in secretory vesicles for production of enkephalin and galanin peptide neurotransmitters.

Journal: Journal of neurochemistry20120801

Title: Enhancement of μ-opioid receptor desensitization by nitric oxide in rat locus coeruleus neurons: involvement of reactive oxygen species.

Journal: The Journal of pharmacology and experimental therapeutics20120801

Title: Differences in basal and ethanol-induced levels of opioid peptides in Wistar rats from five different suppliers.

Journal: Peptides20120701

Title: New insights into the neuroanatomical distribution and phylogeny of opioids and POMC-derived peptides in fish.

Journal: General and comparative endocrinology20120701

Title: Role of bovine adrenal medulla 22 (BAM22) in the pathogenesis of neuropathic pain in rats with spinal nerve ligation.

Journal: European journal of pharmacology20120615

Title: In vivo visualization of delta opioid receptors upon physiological activation uncovers a distinct internalization profile.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20120523

Title: Decreased plasma methionine-enkephalin levels in cluster headache patients.

Journal: American journal of therapeutics20120501

Title: Changes in spinal cord met-enkephalin levels and mechanical threshold values of pain after pulsed radio frequency in a spared nerve injury rat model.

Journal: Neurological research20120501

Title: Hepatic Methionine-enkephalin may interfere with response to antiviral therapy in chronic hepatitis C.

Journal: European journal of gastroenterology & hepatology20120401

Title: Targeting opioidergic pathways as a novel biological treatment for advanced pancreatic cancer.

Journal: Expert review of gastroenterology & hepatology20120401

Title: Conformational space exploration of Met- and Leu-enkephalin using the MOLS method, molecular dynamics, and Monte Carlo simulation--a comparative study.

Journal: Biopolymers20120301

Title: Antinociceptive effect of [Met5]enkephalin semicarbazide is not affected by dipeptidyl carboxypeptidase-I.

Journal: Journal of peptide science : an official publication of the European Peptide Society20120201

Title: Synthesis of quinolinomorphinan-4-ol derivatives as δ opioid receptor agonists.

Journal: Bioorganic & medicinal chemistry20120115

Title: New insights into opioid regulatory pathways: influence of opioids on Wnt1 expression in zebrafish embryos.

Journal: Neuroscience20120103

Title: Endogenous endomorphin-2 contributes to spinal ĸ-opioid antinociception.

Journal: Pharmacology20120101

Title: New findings concerning the mutual action of hormones and receptors.

Journal: In vivo (Athens, Greece)20120101

Title: Endogenous opioids in wound-site neutrophils of sternotomy patients.

Journal: PloS one20120101

Title: Kisspeptin neurons co-express met-enkephalin and galanin in the rostral periventricular region of the female mouse hypothalamus.

Journal: The Journal of comparative neurology20111201

Title: Controlling charge states of peptides through inductive electrospray ionization mass spectrometry.

Journal: Analytical chemistry20111201

Title: Opioid-sensitive GABA inputs from rostromedial tegmental nucleus synapse onto midbrain dopamine neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20111130

Title: Relaxation mode analysis of a peptide system: comparison with principal component analysis.

Journal: The Journal of chemical physics20111028

Title: YFa and analogs: investigation of opioid receptors in smooth muscle contraction.

Journal: World journal of gastroenterology20111028

Title: Multiple replica repulsion technique for efficient conformational sampling of biological systems.

Journal: Biophysical journal20110817

Title: Blockade of adrenomedullin receptors reverses morphine tolerance and its neurochemical mechanisms.

Journal: Behavioural brain research20110801

Title: The opioid growth factor (OGF) and low dose naltrexone (LDN) suppress human ovarian cancer progression in mice.

Journal: Gynecologic oncology20110801

Title: Comparative analysis of Met-enkephalin, galanin and GABA immunoreactivity in the developing trout preoptic-hypophyseal system.

Journal: General and comparative endocrinology20110801

Title: The action of a synthetic derivative of Met5-enkephalin-Arg6-Phe7 on behavioral and endocrine responses.

Journal: Peptides20110801

Title: Microdialysis and mass spectrometric monitoring of dopamine and enkephalins in the globus pallidus reveal reciprocal interactions that regulate movement.

Journal: Journal of neurochemistry20110701

Title: Oxytocin in the periaqueductal gray participates in pain modulation in the rat by influencing endogenous opiate peptides.

Journal: Peptides20110601

Title: Mu-opioid receptor densities are depleted in regions implicated in agonistic and sexual behavior in male European starlings (Sturnus vulgaris) defending nest sites and courting females.

Journal: Behavioural brain research20110516

Title: T lymphocyte proliferation is suppressed by the opioid growth factor ([Met(5)]-enkephalin)-opioid growth factor receptor axis: implication for the treatment of autoimmune diseases.

Journal: Immunobiology20110501

Title: Decrease of lymphoproliferative response by amphetamine is mediated by dopamine from the nucleus accumbens: influence on splenic met-enkephalin levels.

Journal: Brain, behavior, and immunity20110501

Title: Functional modulation of the pathway between dendritic cells (DCs) and CD4+T cells by the neuropeptide: methionine enkephalin (MENK).

Journal: Peptides20110501

Title: HPLC/MS/MS for quantification of two types of neurotransmitters in rat brain and application: myocardial ischemia and protection of Sheng-Mai-San.

Journal: Journal of pharmaceutical and biomedical analysis20110428

Title: Regular exercise reverses sensory hypersensitivity in a rat neuropathic pain model: role of endogenous opioids.

Journal: Anesthesiology20110401

Title: Phylogenetic diversity and functional efficacy of the C-terminally expressed heptapeptide unit in the opioid precursor polypeptide proenkephalin A.

Journal: Neuroscience20110331

Title: Prevention and diminished expression of experimental autoimmune encephalomyelitis by low dose naltrexone (LDN) or opioid growth factor (OGF) for an extended period: Therapeutic implications for multiple sclerosis.

Journal: Brain research20110324

Title: Immune modulation in response to stress and relaxation.

Journal: Pakistan journal of biological sciences : PJBS20110315

Title: Modulation by endogenously released ATP and opioids of chromaffin cell calcium channels in mouse adrenal slices.

Journal: American journal of physiology. Cell physiology20110301

Title: Regulated proenkephalin expression in human skin and cultured skin cells.

Journal: The Journal of investigative dermatology20110301

Title: Sympatholytic delta-2 opioid receptors moderate ganglionic vasomotor control.

Journal: Experimental biology and medicine (Maywood, N.J.)20110301

Title: Intestinal immune response of Silurus glanis and Barbus barbus naturally infected with Pomphorhynchus laevis (Acanthocephala).

Journal: Parasite immunology20110201

Title: B lymphocyte proliferation is suppressed by the opioid growth factor-opioid growth factor receptor axis: Implication for the treatment of autoimmune diseases.

Journal: Immunobiology20110101

Title: Degradation kinetics of methionine5-enkephalin by cerebrospinal fluid: in vitro studies.

Journal: American journal of therapeutics20110101

Title: Met-enkephalins in patients with inflammatory bowel diseases.

Journal: Advances in medical sciences20110101

Title: Predicting antitumor activity of peptides by consensus of regression models trained on a small data sample.

Journal: International journal of molecular sciences20110101

Title: Tolerance to the antinociceptive effect of morphine in the absence of short-term presynaptic desensitization in rat periaqueductal gray neurons.

Journal: The Journal of pharmacology and experimental therapeutics20101201

Title: Investigation of the pyrolysis products of methionine-enkephalin-Arg-Gly-Leu using liquid chromatography-tandem mass spectrometry.

Journal: Journal of mass spectrometry : JMS20101101

Title: Regulation of Tenon's capsule fibroblast cell proliferation by the opioid growth factor and the opioid growth factor receptor axis.

Journal: Investigative ophthalmology & visual science20101001

Title: Opioid modulation of cell proliferation in the ventricular zone of adult zebra finches (Taenopygia guttata).

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20101001

Title: Effects of acute ethanol administration on methionine-enkephalin expression and release in regions of the rat brain.

Journal: Neuropeptides20101001

Title: Internalization of the opioid growth factor, [Met5]-enkephalin, is dependent on clathrin-mediated endocytosis for downregulation of cell proliferation.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology20100901

Title: Rationally designed chimeric peptide of met-enkephalin and FMRFa-[D-Ala2,p-Cl-Phe4]YFa induce multiple opioid receptors mediated antinociception and up-regulate their expression.

Journal: European journal of pharmacology20100725

Title: Non-suicidal self-injurious behavior, endogenous opioids and monoamine neurotransmitters.

Journal: Journal of affective disorders20100701

Title: [Methionine-enkephalin (Met5-Enk) and leucine-enkephalin (Leu5-Enk)].

Journal: Nihon rinsho. Japanese journal of clinical medicine20100701

Title: Modulation of feeding and locomotion through mu and delta opioid receptor signaling in the nucleus accumbens.

Journal: Neuropeptides20100601

Title: Delivery of neuropeptides from the periphery to the brain: studies with enkephalin.

Journal: ACS chemical neuroscience20100519

Title: Analogues of both Leu- and Met-enkephalin containing a constrained dipeptide isostere prepared from a Baylis-Hillman adduct.

Journal: Amino acids20100401

Title: Computational structure-activity study directs synthesis of novel antitumor enkephalin analogs.

Journal: Amino acids20100401

Title: Effect of chronic intra-peritoneally administered chimeric peptide of met-enkephalin and FMRFa-[D-Ala2]YFa-on antinociception and opioid receptor regulation.

Journal: European journal of pain (London, England)20100301

Title: CD10 enhances metastasis of colorectal cancer by abrogating the anti-tumoural effect of methionine-enkephalin in the liver.

Journal: Gut20100301

Title: Topical application of naltrexone facilitates reepithelialization of the cornea in diabetic rabbits.

Journal: Brain research bulletin20100215

Title: Opioids in the hypothalamus control dopamine and acetylcholine levels in the nucleus accumbens.

Journal: Brain research20100202

Title: Opioids in the hypothalamic paraventricular nucleus stimulate ethanol intake.

Journal: Alcoholism, clinical and experimental research20100201

Title: Solution structural investigation and conformation-activity relationship of BAM8-22 by NMR and molecular dynamics simulations.

Journal: Bioorganic & medicinal chemistry letters20100201

Title: Opioid growth factor suppresses expression of experimental autoimmune encephalomyelitis.

Journal: Brain research20100115

Title: Various drug delivery approaches to the central nervous system.

Journal: Expert opinion on drug delivery20100101

Title: Plasma endogenous enkephalin levels in early systemic sclerosis: clinical and laboratory associations.

Journal: Clinical and experimental rheumatology20100101

Title: [M-Enk expressing in the lamina II of cat spinal cord after deafferentation].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition20091101

Title: Opioid growth factor-opioid growth factor receptor axis is a physiological determinant of cell proliferation in diverse human cancers.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology20091001

Title: Endogenous peptide: Met-enkephalin-Arg-Phe, differently regulate expression of opioid receptors on chronic treatment.

Journal: Neuropeptides20091001

Title: Segregation of met-enkephalin from vesicular acetylcholine transporter and choline acetyltransferase in sympathetic preganglionic varicosities mostly lacking synaptophysin and synaptotagmin.

Journal: Neuroscience20090929

Title: Multiple Markov transition matrix method: obtaining the stationary probability distribution from multiple simulations.

Journal: Journal of computational chemistry20090901

Title: Anticonvulsant Met-enkephalin analogues containing backbone spacers reveal alternative non-opioid signaling in the brain.

Journal: ACS chemical biology20090821

Title: Release of endogenous opioids from duodenal enteroendocrine cells requires Trpm5.

Journal: Gastroenterology20090801

Title: Arginine vasopressin antinociception in the rat nucleus raphe magnus is involved in the endogenous opiate peptide and serotonin system.

Journal: Peptides20090701

Title: Buprenorphine is a weak partial agonist that inhibits opioid receptor desensitization.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20090603

Title: Cell proliferation of human ovarian cancer is regulated by the opioid growth factor-opioid growth factor receptor axis.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology20090601

Title: Effect of acute ethanol administration on the release of opioid peptides from the midbrain including the ventral tegmental area.

Journal: Alcoholism, clinical and experimental research20090601

Title: G protein independent phosphorylation and internalization of the delta-opioid receptor.

Journal: Journal of neurochemistry20090601

Title: Cathepsin K generates enkephalin from beta-endorphin: a new mechanism with possible relevance for schizophrenia.

Journal: Neurochemistry international20090601

Title: Design and synthesis of novel delta opioid receptor agonists and their pharmacologies.

Journal: Bioorganic & medicinal chemistry letters20090515

Title: Comparison of predicted native structures of Met-enkephalin based on various accessible-surface-area solvent models.

Journal: Journal of computational chemistry20090501

Title: Antinociception by neutrophil-derived opioid peptides in noninflamed tissue--role of hypertonicity and the perineurium.

Journal: Brain, behavior, and immunity20090501

Title: Regulation of cell proliferation by the OGF-OGFr axis is dependent on nuclear localization signals.

Journal: Experimental biology and medicine (Maywood, N.J.)20090501

Title: Intrathecal transplantation of autologous macrophages genetically modified to secrete proenkephalin ameliorated hyperalgesia and allodynia following peripheral nerve injury in rats.

Journal: Neuroscience research20090501

Title: [Distribution of met-enkephalin expression in the visual pathway. Experimental study by inmunocytochemistry].

Journal: Archivos de la Sociedad Espanola de Oftalmologia20090501

Title: Sensitization to amphetamine occurs simultaneously at immune level and in met-enkephalin of the nucleus accumbens and spleen: an involved NMDA glutamatergic mechanism.

Journal: Brain, behavior, and immunity20090501

Title: Capillary electrophoresis-mass spectrometry using an in-line sol-gel concentrator for the determination of methionine enkephalin in cerebrospinal fluid.

Journal: Talanta20090430

Title: Does the endogenous opiate system play a role in the Restless Legs Syndrome? A pilot post-mortem study.

Journal: Journal of the neurological sciences20090415

Title: Hypertensive state, independent of hypertrophy, exhibits an attenuated decrease in systolic function on cardiac kappa-opioid receptor stimulation.

Journal: American journal of physiology. Heart and circulatory physiology20090401

Title: Gene therapy for pancreatitis pain.

Journal: Gene therapy20090401

Title: Mycobacteria attenuate nociceptive responses by formyl peptide receptor triggered opioid peptide release from neutrophils.

Journal: PLoS pathogens20090401

Title: Practical aspects of in vivo detection of neuropeptides by microdialysis coupled off-line to capillary LC with multistage MS.

Journal: Analytical chemistry20090315

Title: Bounding the electrostatic free energies associated with linear continuum models of molecular solvation.

Journal: The Journal of chemical physics20090314

Title: Two distinct mechanisms mediate acute mu-opioid receptor desensitization in native neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20090311

Title: Methionine-enkephalin secreted by human colorectal cancer cells suppresses T lymphocytes.

Journal: Cancer science20090301

Title: Efficient evaluation of sampling quality of molecular dynamics simulations by clustering of dihedral torsion angles and Sammon mapping.

Journal: Journal of computational chemistry20090201

Title: A prolonged nitric oxide-dependent, opioid-mediated antinociceptive effect of hyperbaric oxygen in mice.

Journal: The journal of pain : official journal of the American Pain Society20090201

Title: Network architecture of gap junction-coupled neuronal linkage in the striatum.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20090128

Title: Neurokinin 1 receptors regulate morphine-induced endocytosis and desensitization of mu-opioid receptors in CNS neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20090107

Title: The effects of selective breeding for differential rates of 50-kHz ultrasonic vocalizations on emotional behavior in rats.

Journal: Developmental psychobiology20090101

Title: Activation of delta-opioid receptors reduces excitatory input to putative gustatory cells within the nucleus of the solitary tract.

Journal: Journal of neurophysiology20090101

Title: Dilution-free analysis from picoliter droplets by nano-electrospray ionization mass spectrometry.

Journal: Angewandte Chemie (International ed. in English)20090101

Title: Freezing of enkephalinergic functions by multiple noxious foci: a source of pain sensitization?

Journal: PloS one20090101

Title: Bacitracin-sensitive aminopeptidase(s) degradation of methionine(5)-enkephalin by human brain putamen and hippocampus preparations: inhibition by phenothiazine drugs.

Journal: American journal of therapeutics20090101

Title: Growth inhibition of thyroid follicular cell-derived cancers by the opioid growth factor (OGF) - opioid growth factor receptor (OGFr) axis.

Journal: BMC cancer20090101

Title: Effects of acute ethanol on opioid peptide release in the central amygdala: an in vivo microdialysis study.

Journal: Psychopharmacology20081201

Title: Lack of tolerance and morphine-induced cross-tolerance to the analgesia of chimeric peptide of Met-enkephalin and FMRFa.

Journal: Peptides20081201

Title: Folding proteins by first-passage-times-optimized replica exchange.

Journal: Physical review. E, Statistical, nonlinear, and soft matter physics20081201

Title: Dynamic changes of the endogenous cannabinoid and opioid mesocorticolimbic systems during adolescence: THC effects.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology20081101

Title: Expression of opioid growth factor (OGF)-OGF receptor (OGFr) axis in human nonmedullary thyroid cancer.

Journal: Thyroid : official journal of the American Thyroid Association20081101

Title: Mu-opioid receptor activation in live cells.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20081001

Title: Possible autocrine enkephalin regulation of catecholamine release in human pheochromocytoma cells.

Journal: Life sciences20080912

Title: Tolerance to repeated morphine administration is associated with increased potency of opioid agonists.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology20080901

Title: Distinct morphological and immunohistochemical features and different growth rates among four human neuroblastomas heterotransplanted into nude mice.

Journal: Medical molecular morphology20080901

Title: Antinociception produced by 14,15-epoxyeicosatrienoic acid is mediated by the activation of beta-endorphin and met-enkephalin in the rat ventrolateral periaqueductal gray.

Journal: The Journal of pharmacology and experimental therapeutics20080801

Title: Effect of chronic administration of morphine on the expression of bovine adrenal medulla 22-like immunoreactivity in the spinal cord of rats.

Journal: European journal of pharmacology20080728

Title: An in vitro comparison of microdialysis relative recovery of Met- and Leu-enkephalin using cyclodextrins and antibodies as affinity agents.

Journal: Analytica chimica acta20080714

Title: Natural linear-scaled coupled-cluster theory with local transferable triple excitations: applications to peptides.

Journal: The journal of physical chemistry. A20080703

Title: Estradiol abolishes reduction in cell death by the opioid agonist Met5-enkephalin after oxygen glucose deprivation in isolated cardiomyocytes from both sexes.

Journal: American journal of physiology. Heart and circulatory physiology20080701

Title: Capillary electrophoresis chemiluminescent detection system equipped with a two-step postcolumn flow interface for detection of some enkephalin-related peptides labeled with acridinium ester.

Journal: Electrophoresis20080601

Title: YFa, a chimeric opioid peptide, induces kappa-specific antinociception with no tolerance development during 6 days of chronic treatment.

Journal: Journal of neuroscience research20080515

Title: Enkephalin elevations contribute to neuronal and behavioral impairments in a transgenic mouse model of Alzheimer's disease.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20080507

Title: Presynaptic actions of opioid receptor agonists in ventromedial hypothalamic neurons in estrogen- and oil-treated female mice.

Journal: Neuroscience20080409

Title: The impact of postnatal environment on opioid peptides in young and adult male Wistar rats.

Journal: Neuropeptides20080401

Title: Methionine-enkephalin modulation of hydrogen peroxide (H2O2) release by rat peritoneal macrophages involves different types of opioid receptors.

Journal: Neuropeptides20080401

Title: Evaluation of a novel aminopeptidase N inhibitor, in vitro, using two assay systems.

Journal: Journal of enzyme inhibition and medicinal chemistry20080401

Title: Role of endogenous opioids in modulating HSC activity in vitro and liver fibrosis in vivo.

Journal: Gut20080301

Title: Reactivity and oxidative potential of fructose and glucose in enkephalin-sugar model systems.

Journal: Amino acids20080201

Title: Involvement of spinal Met-enkephalin in nicotine-induced antinociception in mice.

Journal: Brain research20080116

Title: In vitro methionine5-enkephalin degradation kinetics by human brain preparations.

Journal: Neurochemical research20080101

Title: Liver derived endogenous opioids may interfere with the therapeutic effect of interferon in chronic hepatitis C.

Journal: Medical hypotheses20080101

Title: Sex differences in the mechanism of Met5-enkephalin-induced cardioprotection: role of PI3K/Akt.

Journal: American journal of physiology. Heart and circulatory physiology20080101

Title: The OGF-OGFr axis utilizes the p21 pathway to restrict progression of human pancreatic cancer.

Journal: Molecular cancer20080101

Title: Degradation kinetics of methionine5-enkephalin by select brain areas from patients with chronic schizophrenia.

Journal: American journal of therapeutics20080101

Title: [Pharmacodynamic properties of a combination of met-enkephalin and alpha 1-13 adrenocorticotropic hormone].

Journal: Medicinski arhiv20080101

Title: Differential activation of enkephalin, galanin, somatostatin, NPY, and VIP neuropeptide production by stimulators of protein kinases A and C in neuroendocrine chromaffin cells.

Journal: Neuropeptides20080101

Title: Human hepatic met-enkephalin and delta opioid receptor-1 immunoreactivities in viral and autoimmune hepatitis.

Journal: Annals of hepatology20080101

Title: Compartmental loss of striatal medium spiny neurons in multiple system atrophy of parkinsonian type.

Journal: Movement disorders : official journal of the Movement Disorder Society20071201

Title: Opioids and migration, chemotaxis, invasion, and adhesion of human cancer cells.

Journal: Neuropeptides20071201

Title: Endogenous heptapeptide Met-enkephalin-Gly-Tyr binds differentially to duplicate delta opioid receptors from zebrafish.

Journal: Peptides20071201

Title: Augmented myocardial methionine-enkephalin in a murine model of cardiac angiotensin II-overexpression.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS20071201

Title: On the structural convergence of biomolecular simulations by determination of the effective sample size.

Journal: The journal of physical chemistry. B20071108

Title: CXCR1/2 ligands induce p38 MAPK-dependent translocation and release of opioid peptides from primary granules in vitro and in vivo.

Journal: Brain, behavior, and immunity20071101

Title: The opioid growth factor (OGF)-OGF receptor axis uses the p16 pathway to inhibit head and neck cancer.

Journal: Cancer research20071101

Title: Hamiltonian and distance replica exchange method studies of Met-enkephalin.

Journal: The journal of physical chemistry. B20071025

Title: Live cell monitoring of mu-opioid receptor-mediated G-protein activation reveals strong biological activity of close morphine biosynthetic precursors.

Journal: The Journal of biological chemistry20070914

Title: The involvement of spinal bovine adrenal medulla 22-like peptide, the proenkephalin derivative, in modulation of nociceptive processing.

Journal: The European journal of neuroscience20070901

Title: The enhancing effects of peptidase inhibitors on the antinociceptive action of [Met5]enkephalin-Arg6-Phe7 in rats.

Journal: Journal of pharmacological sciences20070901

Title: Microscopic understanding of preferential exclusion of compatible solute ectoine: direct interaction and hydration alteration.

Journal: The journal of physical chemistry. B20070830

Title: Superoxide radical anions protect enkephalin from oxidation if the amine group is blocked.

Journal: Free radical biology & medicine20070715

Title: Arginine vasopressin induces periaqueductal gray release of enkephalin and endorphin relating to pain modulation in the rat.

Journal: Regulatory peptides20070705

Title: Sensitisation of TRPV1 in rat sensory neurones by activation of SNSRs.

Journal: Neuroscience letters20070705

Title: Influence of pain treatment by epidural fentanyl and bupivacaine on homing of opioid-containing leukocytes to surgical wounds.

Journal: Brain, behavior, and immunity20070701

Title: Beta-endorphin, Met-enkephalin and corresponding opioid receptors within synovium of patients with joint trauma, osteoarthritis and rheumatoid arthritis.

Journal: Annals of the rheumatic diseases20070701

Title: Ethanol-induced effects on opioid peptides in adult male Wistar rats are dependent on early environmental factors.

Journal: Neuroscience20070525

Title: Further studies of tyrosine surrogates in opioid receptor peptide ligands.

Journal: Bioorganic & medicinal chemistry letters20070501

Title: Opioid peptides as possible neuromodulators in the frog peripheral nerve system.

Journal: Neuropeptides20070401

Title: The hop cassette of the PAC1 receptor confers coupling to Ca2+ elevation required for pituitary adenylate cyclase-activating polypeptide-evoked neurosecretion.

Journal: The Journal of biological chemistry20070316

Title: Sensory neuron-specific receptor agonist BAM8-22 inhibits the development and expression of tolerance to morphine in rats.

Journal: Behavioural brain research20070312

Title: Involvement of delta-and mu-opioid receptors in the delayed cerebral ischemic tolerance induced by repeated electroacupuncture preconditioning in rats.

Journal: Chinese medical journal20070305

Title: Overexpression of the opioid growth factor receptor downregulates cell proliferation of human squamous carcinoma cells of the head and neck.

Journal: International journal of molecular medicine20070301

Title: The influence of stress and methionine-enkephalin on macrophage functions in two inbred rat strains.

Journal: Life sciences20070213

Title: Electrophysiological properties of catecholaminergic neurons in the norepinephrine-deficient mouse.

Journal: Neuroscience20070209

Title: GABAergic interneurons facilitate mossy fiber excitability in the developing hippocampus.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20070207

Title: Morphine priming in rats with chronic inflammation reveals a dichotomy between antihyperalgesic and antinociceptive properties of deltorphin.

Journal: Neuroscience20070105

Title: Conformational stability and three-dimensional model of the delta-opioid pharmacophore for the extended antiparallel dimer structure of Met-enkephalin in water.

Journal: Journal of molecular modeling20070101

Title: Reactions of hydrogen atoms with met-enkephalin and related peptides.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20070101

Title: Distinction of neurochemistry between the cores and their shells of auditory nuclei in tetrapod species.

Journal: Brain, behavior and evolution20070101

Title: Differences in neurogenesis differentiate between core and shell regions of auditory nuclei in the turtle (Pelodiscus sinensis): evolutionary implications.

Journal: Brain, behavior and evolution20070101

Title: RB101-mediated protection of endogenous opioids: potential therapeutic utility?

Journal: CNS drug reviews20070101

Title: Plasma met-enkephalin, beta-endorphin and leu-enkephalin levels in human hepatic encephalopathy.

Journal: Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit20070101

Title: Dependence of the analgesic activities of dermorphin, metenkephalin, and dynorphin A on the ambient temperature.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections20070101

Title: [Subacute toxicity study of combination of adrenocorticotropine 1-13 and met-enkephalin].

Journal: Medicinski arhiv20070101

Title: Human opioid peptide Met-enkephalin binds to anionic phosphatidylserine in high preference to zwitterionic phosphatidylcholine: natural-abundance 13C NMR study on the binding state in large unilamellar vesicles.

Journal: Biochemistry20061226

Title: Arginine vasopressin enhances periaqueductal gray synthesis and secretion of enkephalin and endorphin in the rat.

Journal: Brain research bulletin20061211

Title: Repeated delta1-opioid receptor stimulation reduces delta2-opioid receptor responses in the SA node.

Journal: American journal of physiology. Heart and circulatory physiology20061101

Title: The monosialosyl ganglioside GM-1 reduces the vagolytic efficacy of delta2-opioid receptor stimulation.

Journal: American journal of physiology. Heart and circulatory physiology20061101

Title: Conformational study of Met-enkephalin based on the ECEPP force fields.

Journal: Biophysical journal20061001

Title: The distribution of substance P and met-enkephalin in vocal control nuclei among oscine species and its relation to song complexity.

Journal: Behavioural brain research20060925

Title: Choline acetyl transferase and neuropeptide immunoreactivities are colocalized in somata, but preferentially localized in distinct axon fibers and boutons of cat sympathetic preganglionic neurons.

Journal: Synapse (New York, N.Y.)20060915

Title: Vagal afferent control of opioidergic effects in rat brainstem circuits.

Journal: The Journal of physiology20060915

Title: Effects of chronic ethanol administration on brain interstitial fluid levels of Methionine-enkephalin as measured by microdialysis in vivo.

Journal: Peptides20060901

Title: Amphetamine triggers an increase in met-enkephalin simultaneously in brain areas and immune cells.

Journal: Journal of neuroimmunology20060901

Title: Kappa-opioid receptors mediate cardioprotection by remote preconditioning.

Journal: Anesthesiology20060901

Title: Opiate receptor binding properties of morphine-, dihydromorphine-, and codeine 6-O-sulfate ester congeners.

Journal: Bioorganic & medicinal chemistry letters20060815

Title: Simultaneous activation of the delta opioid receptor (deltaOR)/sensory neuron-specific receptor-4 (SNSR-4) hetero-oligomer by the mixed bivalent agonist bovine adrenal medulla peptide 22 activates SNSR-4 but inhibits deltaOR signaling.

Journal: Molecular pharmacology20060801

Title: Ab initio protein fold prediction using evolutionary algorithms: influence of design and control parameters on performance.

Journal: Journal of computational chemistry20060801

Title: Met5-enkephalin-Arg6-Phe7 (MEAP): a cardioprotective hormonal opioid.

Journal: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine20060801

Title: Opioid growth factor receptor is unaltered with the progression of human pancreatic and colon cancers.

Journal: International journal of oncology20060801

Title: Chimeric peptide of met-enkephalin and FMRFa: effect of chlorination on conformation and analgesia.

Journal: Neuroscience letters20060731

Title: Effect of starvation on Fos and neuropeptide immunoreactivities in the brain and pituitary gland of Xenopus laevis.

Journal: General and comparative endocrinology20060701

Title: Enkephalinergic afferents of the centromedial amygdala in the rat.

Journal: The Journal of comparative neurology20060620

Title: Evaluation of efficiency of reference potential spatial warping algorithm in conformational sampling of peptides.

Journal: The Journal of chemical physics20060607

Title: Proenkephalin peptide F immunoreactivity in different circulatory biocompartments after exercise.

Journal: Peptides20060601

Title: Endogenous opioid-mediated antinociception in cholestatic mice is peripherally, not centrally, mediated.

Journal: Journal of hepatology20060601

Title: Variations in opioid peptide levels during the estrous cycle in Sprague-Dawley rats.

Journal: Neuropeptides20060601

Title: A pulsed field gradient NMR diffusion investigation of enkephalin peptide-sodium dodecyl sulfate micelle association.

Journal: Magnetic resonance in chemistry : MRC20060601

Title: Tumor-cell-targeted methionine-enkephalin analogues containing unnatural amino acids: design, synthesis, and in vitro antitumor activity.

Journal: Journal of medicinal chemistry20060601

Title: Vibrational dynamics of morphine in relation to Leu5--and Met5-enkephalins.

Journal: Indian journal of biochemistry & biophysics20060601

Title: Delta and mu opioid receptors from the brain of a urodele amphibian, the rough-skinned newt Taricha granulosa: cloning, heterologous expression, and pharmacological characterization.

Journal: General and comparative endocrinology20060501

Title: Endogenous opioids modulate the growth of the biliary tree in the course of cholestasis.

Journal: Gastroenterology20060501

Title: Capillary electrophoretic competitive immunoassay with laser-induced fluorescence detection for methionine-enkephalin.

Journal: Journal of chromatography. A20060414

Title: Preproenkephalin targeted antisenses cross the blood-brain barrier to reduce brain methionine enkephalin levels and increase voluntary ethanol drinking.

Journal: Peptides20060401

Title: Cell therapy of pain: Characterization of human fetal chromaffin cells at early adrenal medulla development.

Journal: Experimental neurology20060401

Title: Vagotonic effects of enkephalin are not mediated by sympatholytic mechanisms.

Journal: Experimental biology and medicine (Maywood, N.J.)20060401

Title: Bovine adrenal medulla 22 reverses antinociceptive morphine tolerance in the rat.

Journal: Behavioural brain research20060315

Title: Theoretical studies of transition states by the multioverlap molecular dynamics methods.

Journal: The Journal of chemical physics20060314

Title: Influence of the menstrual cycle on proenkephalin peptide F responses to maximal cycle exercise.

Journal: European journal of applied physiology20060301

Title: A new method to determine electrostatic potential around a macromolecule in solution from molecular wave functions.

Journal: Journal of computational chemistry20060301

Title: Complex regional pain syndrome and methionine-enkephalin.

Journal: Clinical chemistry20060301

Title: Determination of enkephalin peptides by nonaqueous capillary electrophoresis with electrochemical detection.

Journal: Electrophoresis20060301

Title: The superior colliculus of the camel: a neuronal-specific nuclear protein (NeuN) and neuropeptide study.

Journal: Journal of anatomy20060201

Title: Involvement of caspase-3 pathway in anti-apoptotic action of methionine enkephalin on CEM x 174 cells in prolonged infection with simian immunodeficiency virus in vitro.

Journal: Cell biology international20060201

Title: Methionine-enkephalin modulated regulation of oxidant/antioxidant status in liver of CBA mice.

Journal: Biogerontology20060201

Title: Synthesis, conformational and pharmacological studies of glycosylated chimeric peptides of Met-enkephalin and FMRFa.

Journal: Brain research bulletin20060130

Title: A new electrochemical HPLC method for analysis of enkephalins and endomorphins.

Journal: Journal of neuroscience methods20060115

Title: Perinatal ethanol exposure alters met-enkephalin levels of male and female rats.

Journal: Neurotoxicology and teratology20060101

Title: Genetically engineered human mesenchymal stem cells produce met-enkephalin at augmented higher levels in vitro.

Journal: Cell transplantation20060101

Title: Endogenous signaling complexity in neuropeptides- leucine- and methionine-enkephalin.

Journal: Cellular and molecular neurobiology20060101

Title: Aspects of central and peripheral regulation of reproduction in mammals.

Journal: Reproductive biology20060101

Title: Effect of prolonged progesterone treatment on the proenkephalin mRNA gene expression and enkephalins concentration in the sheep brain.

Journal: Reproductive biology20060101

Title: Met-enkephalin in the liver as a marker of hepatocellular damage in chronic viral hepatitis type B and C.

Journal: Advances in medical sciences20060101

Title: Validation of the l-dopa-induced dyskinesia in the 6-OHDA model and evaluation of the effects of selective dopamine receptor agonists and antagonists.

Journal: Brain research bulletin20051215

Title: Met-enkephalin effects on histamine-induced bronchoconstriction in guinea pigs.

Journal: Collegium antropologicum20051201

Title: Immunohistochemical reactions of receptors to met-enkephalin, VIP, substance P, and CGRP located on Merkel cells in the rat sinus hair follicle.

Journal: Archives of histology and cytology20051201

Title: Substrate access to the active sites in aminopeptidase T, a representative of a new metallopeptidase clan.

Journal: Journal of molecular biology20051125

Title: Energy landscapes and properties of biomolecules.

Journal: Physical biology20051109

Title: Combination chemotherapy with gemcitabine and biotherapy with opioid growth factor (OGF) enhances the growth inhibition of pancreatic adenocarcinoma.

Journal: Cancer chemotherapy and pharmacology20051101

Title: Postsynaptic actions of substance P on rat periaqueductal grey neurons in vitro.

Journal: Neuropharmacology20051001

Title: Ischemic preconditioning increases the bioavailability of cardiac enkephalins.

Journal: American journal of physiology. Heart and circulatory physiology20051001

Title: Opioids and differentiation in human cancer cells.

Journal: Neuropeptides20051001

Title: A microdialysis profile of Met-enkephalin release in the rat nucleus accumbens following alcohol administration.

Journal: Alcoholism, clinical and experimental research20051001

Title: Attenuation of pain perception after transposition of the greater omentum to the cauda equina region of rats--a preliminary observation.

Journal: Neurological research20050901

Title: Role of methionine-enkephalin on the regulation of carbohydrate metabolism in the rice field crab Oziotelphusa senex senex.

Journal: Comptes rendus biologies20050901

Title: Capillary liquid chromatography and tandem mass spectrometry for the quantification of enkephalins in cerebrospinal fluid.

Journal: Journal of separation science20050901

Title: Binding profile of the endogenous novel heptapeptide Met-enkephalin-Gly-tyr in zebrafish and rat brain.

Journal: The Journal of pharmacology and experimental therapeutics20050801

Title: [Methionine-enkephalin (Met-Enk) and leucine-enkephalin (Leu-Enk)].

Journal: Nihon rinsho. Japanese journal of clinical medicine20050801

Title: The influence of cell growth media on the stability and antitumour activity of methionine enkephalin.

Journal: Journal of peptide science : an official publication of the European Peptide Society20050701

Title: Opioid growth factor enhances tumor growth inhibition and increases the survival of paclitaxel-treated mice with squamous cell carcinoma of the head and neck.

Journal: Cancer chemotherapy and pharmacology20050701

Title: Inhibition of neuronal nitric oxide synthase attenuates the development of morphine tolerance in rats.

Journal: Synapse (New York, N.Y.)20050701

Title: Effects of maternal separation on voluntary ethanol intake and brain peptide systems in female Wistar rats.

Journal: Pharmacology, biochemistry, and behavior20050701

Title: Particle-mediated gene transfer of opioid growth factor receptor cDNA regulates cell proliferation of the corneal epithelium.

Journal: Cornea20050701

Title: Rugged Metropolis sampling with simultaneous updating of two dynamical variables.

Journal: Physical review. E, Statistical, nonlinear, and soft matter physics20050701

Title: Met-enkephalin involvement in morphine-modulated peritonitis in swiss mice.

Journal: Mediators of inflammation20050609

Title: Influence of naloxone on catecholamine release evoked by nicotinic receptor stimulation in the isolated rat adrenal gland.

Journal: Archives of pharmacal research20050601

Title: Lymphocytic ppENKmRNA, MEK-IR, and Dyn-IR in electroacupuncture.

Journal: Bulletin of experimental biology and medicine20050601

Title: Maternal deprivation increases vulnerability to morphine dependence and disturbs the enkephalinergic system in adulthood.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20050504

Title: A simple method for faster nonbonded force evaluations.

Journal: Journal of computational chemistry20050501

Title: Effects of met-enkephalin on cell proliferation in different models of adrenocortical-cell growth.

Journal: International journal of molecular medicine20050501

Title: [Met-enkephalin in the cerebrospinal fluid as an indicator of central nervous system injury in meningitis and encephalitis].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego20050501

Title: Proopiomelanocortin neurons in nucleus tractus solitarius are activated by visceral afferents: regulation by cholecystokinin and opioids.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20050406

Title: Long-term infusion of Met5-enkephalin fails to protect murine hearts against ischemia-reperfusion injury.

Journal: American journal of physiology. Heart and circulatory physiology20050401

Title: Met5-enkephalin-induced cardioprotection occurs via transactivation of EGFR and activation of PI3K.

Journal: American journal of physiology. Heart and circulatory physiology20050401

Title: Differential mechanisms of antianalgesia induced by endomorphin-1 and endomorphin-2 in the ventral periaqueductal gray of the rat.

Journal: The Journal of pharmacology and experimental therapeutics20050301

Title: Enhanced growth inhibition of squamous cell carcinoma of the head and neck by combination therapy of paclitaxel and opioid growth factor.

Journal: International journal of oncology20050301

Title: Withdrawal following sufentanil/propofol and sufentanil/midazolam. Sedation in surgical ICU patients: correlation with central nervous parameters and endogenous opioids.

Journal: Intensive care medicine20050301

Title: Substance P and opioid peptidergic innervation of the anterior eye segment of the rat: an immunohistochemical study.

Journal: Journal of anatomy20050301

Title: Hypotensive effect of novel chimeric peptides of met-enkephalin and FMRFa.

Journal: Regulatory peptides20050215

Title: Peptidergic neuromodulation of the lumbar locomotor network in the neonatal rat spinal cord.

Journal: Peptides20050201

Title: Capillary liquid chromatography with MS3 for the determination of enkephalins in microdialysis samples from the striatum of anesthetized and freely-moving rats.

Journal: Journal of mass spectrometry : JMS20050201

Title: Selective involvement of opioids in the mechanisms of synapse-specific plasticity in the common snail during the acquisition of sensitization.

Journal: Neuroscience and behavioral physiology20050201

Title: Structural characterization of methionine and leucine enkephalins by hydrogen/deuterium exchange and electrospray ionization tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM20050101

Title: Nucleocytoplasmic distribution of opioid growth factor and its receptor in tongue epithelium.

Journal: The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology20050101

Title: Met-enkephalin modulation of age-related changes in red cell antioxidant status.

Journal: Physiological research20050101

Title: delta-opioid receptor-mediated actions on rostral ventromedial medulla neurons.

Journal: Neuroscience20050101

Title: Mu-opioid-mediated inhibition of glutamate synaptic transmission in rat central amygdala neurons.

Journal: Neuroscience20050101

Title: [Spatial structure of BAM-12P dodecapeptide and its analogues].

Journal: Bioorganicheskaia khimiia20050101

Title: In vitro modulation of cytokine expression by enkephalin-derived peptides.

Journal: Neuroimmunomodulation20050101

Title: Distribution of methionine and leucine enkephalin neurons within the social behavior circuitry of the male Syrian hamster brain.

Journal: Brain research20041224

Title: Effects of intrathecal BAM22 on noxious stimulus-evoked c-fos expression in the rat spinal dorsal horn.

Journal: Brain research20041203

Title: Grafts of immortalized chromaffin cells bio-engineered to improve met-enkephalin release also reduce formalin-evoked c-fos expression in rat spinal cord.

Journal: Neuroscience letters20041103

Title: Maternal separation alters maternal care, but has minor effects on behavior and brain opioid peptides in adult offspring.

Journal: Developmental psychobiology20041101

Title: Met-enkephalin modulates resistance to oxidative stress in mouse brain.

Journal: Neuropeptides20041001

Title: Chronic morphine treatment reduces recovery from opioid desensitization.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20040901

Title: The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat.

Journal: European journal of pharmacology20040616

Title: Non-opioid actions of opioid peptides.

Journal: Life sciences20040604

Title: Opioid growth factor (OGF) inhibits anchorage-independent growth in human cancer cells.

Journal: International journal of oncology20040601

Title: Chemoarchitectonic subdivisions of the songbird septum and a comparative overview of septum chemical anatomy in jawed vertebrates.

Journal: The Journal of comparative neurology20040531

Title: Relative contribution of endogenous opioids to myocardial ischemic tolerance.

Journal: The Journal of surgical research20040501

Title: Influence of ethanol dependence and methionine enkephalin antisense on serum endomorphin-1 and methionine enkephalin levels.

Journal: Alcoholism, clinical and experimental research20040501

Title: Intrathecal xenogeneic chromaffin cell grafts reduce nociceptive behavior in a rodent tonic pain model.

Journal: Experimental neurology20040401

Title: Differential regulation of hippocampal progenitor proliferation by opioid receptor antagonists in running and non-running spontaneously hypertensive rats.

Journal: The European journal of neuroscience20040401

Title: Metabolism and absorption enhancement of methionine enkephalin in human nasal epithelium.

Journal: Peptides20040401

Title: Effect of estradiol on expression and activation of Akt protein in rat hypothalamus exposed to chronic [D-Met2, Pro5]-enkephalinamide treatment.

Journal: Steroids20040401

Title: PEACH 4 with ABINIT-MP: a general platform for classical and quantum simulations of biological molecules.

Journal: Computational biology and chemistry20040401

Title: Neuropeptide Y-mediated inhibition of proopiomelanocortin neurons in the arcuate nucleus shows enhanced desensitization in ob/ob mice.

Journal: Neuron20040304

Title: Neuropathological evaluation of the diencephalon, basal ganglia and upper brainstem in alobar holoprosencephaly.

Journal: Acta neuropathologica20040301

Title: A multidimensional 1H NMR investigation of the conformation of methionine-enkephalin in fast-tumbling bicelles.

Journal: Biophysical journal20040301

Title: Endogenous peripheral antinociception in early inflammation is not limited by the number of opioid-containing leukocytes but by opioid receptor expression.

Journal: Pain20040301

Title: Gene expression of OGFr in the developing and adult rat brain and cerebellum.

Journal: Brain research bulletin20040301

Title: Dual effects of intrathecal BAM22 on nociceptive responses in acute and persistent pain--potential function of a novel receptor.

Journal: British journal of pharmacology20040201

Title: Insights on the interaction of met-enkephalin with negatively charged membranes--an infrared and solid-state NMR spectroscopic study.

Journal: Chemistry and physics of lipids20040201

Title: Responses of plasma proenkephalin peptide F in rats following 14 days of spaceflight.

Journal: Aviation, space, and environmental medicine20040201

Title: Opioid growth factor inhibition of a human squamous cell carcinoma of the head and neck in nude mice: dependency on the route of administration.

Journal: International journal of oncology20040101

Title: Immunocytochemical distribution of Met-enkephalin-Arg6-Gly7-Leu8 (Met-8) in the auditory system of the rat.

Journal: Hearing research20040101

Title: Signaling pathway involved in methionine enkephalin-promoted survival of lymphocytes infected by simian immunodeficiency virus in the early stage in vitro.

Journal: International immunopharmacology20040101

Title: Production and characterization of antibodies for the specific determination of the opioid peptide Met5-Enkephalin-Arg6-Phe7.

Journal: Scandinavian journal of clinical and laboratory investigation20040101

Title: Modulation of delayed-type hypersensitivity responses in hairless guinea pigs by peptides derived from enkephalin.

Journal: Neuroimmunomodulation20040101

Title: Cloning of prodynorphin cDNAs from the brain of Australian and African lungfish: implications for the evolution of the prodynorphin gene.

Journal: Neuroendocrinology20040101

Title: Evidence for the involvement of an opioid system in sciatic nerve of Rana ridibunda.

Journal: Neuropeptides20040101

Title: An immunocytochemical mapping of methionine-enkephalin-Arg(6)-Gly(7)-Leu(8) in the human brainstem.

Journal: Neuroscience20040101

Title: Methionine-enkephalin stimulates hydrogen peroxide and nitric oxide production in rat peritoneal macrophages: interaction of mu, delta and kappa opioid receptors.

Journal: Neuroimmunomodulation20040101

Title: Cerebrospinal fluid levels of opioid peptides in fibromyalgia and chronic low back pain.

Journal: BMC musculoskeletal disorders20040101

Title: Sustained exogenous administration of Met5-enkephalin protects against infarction in vivo.

Journal: American journal of physiology. Heart and circulatory physiology20031201

Title: Stress applied during primary immunization affects the secondary humoral immune response in the rat: involvement of opioid peptides.

Journal: Stress (Amsterdam, Netherlands)20031201

Title: Effects of chronic ethanol on brain and serum level of methionine enkephalin.

Journal: Peptides20031201

Title: Cardiac enkephalins attenuate vagal bradycardia: interactions with NOS-1-cGMP systems in canine sinoatrial node.

Journal: American journal of physiology. Heart and circulatory physiology20031101

Title: Comparison of epigenetic and genetic alterations in mucinous cystic neoplasm and serous microcystic adenoma of pancreas.

Journal: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc20031101

Title: An opioid basis for early-phase isoflurane-induced hypotension in rats.

Journal: Life sciences20031003

Title: Effects of endogenous and synthetic opioid peptides on neutrophil function in vitro.

Journal: British journal of anaesthesia20031001

Title: Opioid growth factor (OGF) inhibits the progression of human squamous cell carcinoma of the head and neck transplanted into nude mice.

Journal: Cancer letters20030925

Title: The regulation of steroidogenesis by opioid peptides in porcine theca cells.

Journal: Animal reproduction science20030915

Title: Activation of delta- and kappa-opioid receptors by opioid peptides protects cardiomyocytes via KATP channels.

Journal: American journal of physiology. Heart and circulatory physiology20030901

Title: Close apposition of dynorphin-positive nerve fibres to lymphocytes in the liver suggests opioidergic neuroimmunomodulation.

Journal: Histochemistry and cell biology20030901

Title: Bimodal delta-opioid receptors regulate vagal bradycardia in canine sinoatrial node.

Journal: American journal of physiology. Heart and circulatory physiology20030901

Title: c-Fos and peptide immunoreactivities in the central extended amygdala of morphine-dependent rats after naloxone-precipitated withdrawal.

Journal: The European journal of neuroscience20030901

Title: Aggression and the three opioid families (endorphins, enkephalins, and dynorphins) in mice.

Journal: Behavior genetics20030901

Title: A genetic algorithm with conformational memories for structure prediction of polypeptides.

Journal: Journal of biomolecular structure & dynamics20030801

Title: Opioid peptides modulate the response of neurons of the superficial laminae of the rat spinal dorsal horn to GABA.

Journal: Biochemical and biophysical research communications20030801

Title: Effect of synthetic oligopeptides on osteoporosis.

Journal: Preparative biochemistry & biotechnology20030801

Title: Different mechanisms of intrinsic pain inhibition in early and late inflammation.

Journal: Journal of neuroimmunology20030801

Title: Interaction of the neuropeptide met-enkephalin with zwitterionic and negatively charged bicelles as viewed by 31P and 2H solid-state NMR.

Journal: Biophysical journal20030701

Title: Effects and mechanisms of melatonin on immune responses in mice of different months.

Journal: Acta pharmacologica Sinica20030701

Title: Effects of neurotransmitters on the chemokinesis and chemotaxis of MDA-MB-468 human breast carcinoma cells.

Journal: Breast cancer research and treatment20030701

Title: Enkephalinergic involvement in substantia nigra in the modulation of hypothalamically-induced predatory attack behavior.

Journal: Indian journal of physiology and pharmacology20030701

Title: Study of serum lipid profile changes in Met-enkephalin treated rats.

Journal: Indian journal of physiology and pharmacology20030701

Title: Presence of opioid growth factor and its receptor in the normal dog, cat and horse cornea.

Journal: Veterinary ophthalmology20030601

Title: Developmental changes in the inhibition of cultured rat uterine cell proliferation by opioid peptides.

Journal: Cell proliferation20030601

Title: Uterus-innervating neurones in porcine inferior mesenteric ganglion: an immunohistochemical characteristic.

Journal: Anatomia, histologia, embryologia20030601

Title: Anatomical relationship between enkephalin-containing neurones and caecum-projecting neurones in the chicken intestinal nerve.

Journal: Anatomia, histologia, embryologia20030601

Title: Formation of dendritic spines in cultured striatal neurons depends on excitatory afferent activity.

Journal: The European journal of neuroscience20030601

Title: Selective roles for the PC2 processing enzyme in the regulation of peptide neurotransmitter levels in brain and peripheral neuroendocrine tissues of PC2 deficient mice.

Journal: Neuropeptides20030601

Title: Long-term effects of short and long periods of maternal separation on brain opioid peptide levels in male Wistar rats.

Journal: Neuropeptides20030601

Title: The selective action of opioid peptides on excitability and the various sensory inputs of defensive behavior command neurons LPl1 and RPl1 of the common snail.

Journal: Neuroscience and behavioral physiology20030601

Title: Cardiac enkephalins interrupt vagal bradycardia via delta 2-opioid receptors in sinoatrial node.

Journal: American journal of physiology. Heart and circulatory physiology20030501

Title: Endogenous opioid peptides contribute to antinociceptive potency of intrathecal [Dmt1]DALDA.

Journal: The Journal of pharmacology and experimental therapeutics20030501

Title: Purification and quantification of opioid peptides in bone and joint tissues--a methodological study in the rat.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society20030501

Title: Methionine enkephalin suppresses metabolic activity of a leukemic cell line (NALM-1) and enhances CD10 expression.

Journal: International immunopharmacology20030501

Title: Cellular actions of opioids on periaqueductal grey neurons from C57B16/J mice and mutant mice lacking MOR-1.

Journal: British journal of pharmacology20030501

Title: Central D-Ala2-Met5-enkephalinamide mu/delta-opioid receptor activation reverses the anxiogenic-like properties of cholecystokinin on locomotor and rearing activity in CD-1 mice.

Journal: Brain research20030425

Title: Central D-Ala2-Met5-enkephalinamide mu/delta-opioid receptor activation blocks behavioral sensitization to cholecystokinin in CD-1 mice.

Journal: Brain research20030425

Title: Ca2+-independent protein kinase Cs mediate heterologous desensitization of leukocyte chemokine receptors by opioid receptors.

Journal: The Journal of biological chemistry20030411

Title: An immunocytochemical mapping of methionine-enkephalin-Arg6-Gly7-Leu8 in the cat brainstem.

Journal: Anatomy and embryology20030401

Title: Immunoelectron microscopic localization of the opioid growth factor receptor (OGFr) and OGF in the cornea.

Journal: Brain research20030328

Title: Opioid modulation of taste responses in the nucleus of the solitary tract.

Journal: Brain research20030307

Title: Opioid growth factor inhibits intimal hyperplasia in balloon-injured rat carotid artery.

Journal: Journal of vascular surgery20030301

Title: Peptide separations and dissociation constants in nonaqueous capillary electrophoresis: comparison of methanol and aqueous buffers.

Journal: Electrophoresis20030301

Title: A comparison between electrokinetic capillary chromatography and absorption spectroscopy for the analysis of peptide-micelle association by weak hydrophobic interactions.

Journal: Electrophoresis20030301

Title: Influence of ovarian sex steroids on spinal methionine-enkephalin release: comparison with dynorphin reveals asymmetrical regulation.

Journal: The Journal of pharmacology and experimental therapeutics20030201

Title: Hybrid global optimization algorithms for protein structure prediction: alternating hybrids.

Journal: Biophysical journal20030201

Title: Up-regulation of methionine-enkephalin-like immunoreactivity by 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment in the forebrain of the Long-Evans rat.

Journal: Journal of chemical neuroanatomy20030201

Title: Behavioral and neuroendocrine actions of the Met-enkephalin-related peptide MERF.

Journal: Hormones and behavior20030201

Title: A new cytokine: the possible effect pathway of methionine enkephalin.

Journal: World journal of gastroenterology20030115

Title: In vitro human plasma leucine(5)-enkephalin degradation is inhibited by a select number of drugs with the phenothiazine molecule in their chemical structure.

Journal: Pharmacology20030101

Title: Enkephalin degradating enzymes in pheochromocytoma patients.

Journal: Oncology reports20030101

Title: Modulation of peripheral endogenous opioid analgesia by central afferent blockade.

Journal: Anesthesiology20030101

Title: Antinociceptive effect of calcitonin gene-related peptide in the central nucleus of amygdala: activating opioid receptors through amygdala-periaqueductal gray pathway.

Journal: Neuroscience20030101

Title: [The role of neuropeptides in brain asymmetry].

Journal: Zhurnal evoliutsionnoi biokhimii i fiziologii20030101

Title: Conformational sampling by self-organization.

Journal: Journal of chemical information and computer sciences20030101

Title: Effect of exogenous opioid peptides on TNF-alpha-induced human neutrophil apoptosis in vitro.

Journal: Archivum immunologiae et therapiae experimentalis20030101

Title: Inflammation-induced alternations in local and central Met-enkephalin in mice.

Journal: Polish journal of pharmacology20030101

Title: Dynorphinergic GABA neurons are a target of both typical and atypical antipsychotic drugs in the nucleus accumbens shell, central amygdaloid nucleus and thalamic central medial nucleus.

Journal: Neuroscience20030101

Title: Tetanus neurotoxin-insensitive vesicle-associated membrane protein localizes to a presynaptic membrane compartment in selected terminal subsets of the rat brain.

Journal: Neuroscience20030101

Title: The probability distribution of side-chain conformations in [Leu] and [Met]enkephalin determines the potency and selectivity to mu and delta opiate receptors.

Journal: Biopolymers20030101

Title: [Met-enkephalin plasma concentration and content in liver tissue in patients with primary biliary cirrhosis].

Journal: Przeglad lekarski20030101

Title: [Selective involvement of opioids in mechanisms of synapse-specific plasticity in Helix lucorum snail during sensitization acquisition].

Journal: Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova20030101

Title: [Comparative study of neurochemical compensation of brain dysfunctions in mammals].

Journal: Zhurnal evoliutsionnoi biokhimii i fiziologii20030101

Title: Organization of the avian basal forebrain: chemical anatomy in the parrot (Melopsittacus undulatus).

Journal: The Journal of comparative neurology20021223

Title: Dopaminergic system modulation of nociceptive response in long-term diabetic rats.

Journal: Pharmacology, biochemistry, and behavior20021201

Title: Plasma levels of opioid peptides after sunbed exposures.

Journal: The British journal of dermatology20021201

Title: Methionine-enkephalin and leucine-enkephalin increase interleukin-1 beta release in mixed glia cultures.

Journal: Neuropeptides20021201

Title: Effect of cerebral ventricles perfusion with morphiceptin and Met-enkephalin on trigemino-hypoglossal reflex in rats.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society20021201

Title: Met-enkephalin modulates lipid peroxidation and total sialic acid level in CBA mice in age- and sex-dependent manners.

Journal: Experimental gerontology20021201

Title: [Opioid mechanism of regulation of the autonomic and motor functions in rabbits].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova20021201

Title: Correlated morphological and chemical phenotyping in myenteric type V neurons of porcine ileum.

Journal: The Journal of comparative neurology20021104

Title: [Met5]enkephalin-Arg-Gly-Leu-induced antinociception is greatly increased by peptidase inhibitors.

Journal: European journal of pharmacology20021018

Title: Naltrexone, an opioid antagonist, facilitates reepithelialization of the cornea in diabetic rat.

Journal: Diabetes20021001

Title: Integration of solid-phase extraction membranes for sample multiplexing: application to rapid protein identification from gel-isolated protein extracts.

Journal: Electrophoresis20021001

Title: Different effects of methionine-enkephalin on paw edema in two inbred rat strains.

Journal: Peptides20020901

Title: Met-enkephalin immunoreactive neurons recruited by acute stress are innervated by axon terminals immunopositive for tyrosine hydroxylase and dopamine-alpha-hydroxylase in the anterolateral division of bed nuclei of the stria terminalis in the rat.

Journal: The European journal of neuroscience20020901

Title: Effects and mechanisms of melatonin on inflammatory and immune responses of adjuvant arthritis rat.

Journal: International immunopharmacology20020901

Title: Conditioned opioid withdrawal decreases nociceptin/orphanin FQ levels in the frontal cortex and olfactory tubercle.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology20020801

Title: GABA-opioid interactions in the globus pallidus: [D-Ala2]-Met-enkephalinamide attenuates potassium-evoked GABA release after nigrostriatal lesion.

Journal: Journal of neurochemistry20020801

Title: Effect of synthetic oligopeptides on osteoporosis.

Journal: Preparative biochemistry & biotechnology20020801

Title: Influence of opioid peptides on human neutrophil apoptosis and activation in vitro.

Journal: Mediators of inflammation20020801

Title: Control of non-adrenergic non-cholinergic reflex motor responses in circular muscle of guinea-pig small intestine by Met-enkephalin.

Journal: Autonomic & autacoid pharmacology20020801

Title: Induction of antinociception and increased met-enkephalin plasma levels by cyclosporine and morphine in rats: implications of the combined use of cyclosporine and morphine and acute posttransplant neuropsychosis.

Journal: The Journal of surgical research20020701

Title: Inhibitory effects of opioids on voltage-dependent Ca(2+) channels and catecholamine secretion in cultured porcine adrenal chromaffin cells.

Journal: Brain research20020628

Title: Striatal neurochemical changes in transgenic models of Huntington's disease.

Journal: Journal of neuroscience research20020615

Title: G-protein-gated potassium channels containing Kir3.2 and Kir3.3 subunits mediate the acute inhibitory effects of opioids on locus ceruleus neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20020601

Title: Met-enkephalin and preproenkephalin mRNA changes in the striatum of the nicotine abstinence mouse.

Journal: Neuroscience letters20020531

Title: Potentiation of the excitatory action of NMDA in ventrolateral periaqueductal gray by the mu-opioid receptor agonist, DAMGO.

Journal: Brain research20020510

Title: Palladium(II) complexes, as synthetic peptidases, regioselectively cleave the second peptide bond 'upstream' from methionine and histidine side chains.

Journal: Journal of the American Chemical Society20020501

Title: beta-Endorphin modulation of pressor response to hyperventilation in hypertensive patients.

Journal: Peptides20020501

Title: Evidence for changes in brain enkephalin contents associated to male rat sexual activity.

Journal: Behavioural brain research20020401

Title: Long time dynamics of Met-enkephalin: comparison of explicit and implicit solvent models.

Journal: Biophysical journal20020401

Title: Hepatic Met-enkephalin immunoreactivity is enhanced in primary biliary cirrhosis.

Journal: Liver20020401

Title: [Implication of the neuropeptides methionine enkephalin, neurotensin and somatostatin of the caudal trigeminal nucleus in the experimental migraine].

Journal: Revista de neurologia20020401

Title: Occurrence, co-occurrence and topographic distribution of choline acetyl transferase, Met-enkephalin and neurotensin in the stellate ganglion of the cat.

Journal: Synapse (New York, N.Y.)20020301

Title: Endomorphins, Met-enkephalin, Tyr-MIF-1, and the P-glycoprotein efflux system.

Journal: Drug metabolism and disposition: the biological fate of chemicals20020301

Title: Monte Carlo sampling algorithm for searching a scale-transformed energy space of polypeptides.

Journal: Journal of computational chemistry20020301

Title: Effect of tianeptine and fluoxetine on the levels of Met-enkephalin and mRNA encoding proenkephalin in the rat.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society20020301

Title: Effect of synthetic beta-endorphin-like peptide immunorphin on human T lymphocytes.

Journal: Biochemistry. Biokhimiia20020301

Title: Enkephalinergic control of the secretory activity of neurons producing stereoisomers of crustacean hyperglycemic hormone in the eyestalk of the crayfish Orconectes limosus.

Journal: The Journal of comparative neurology20020225

Title: Global optimization by energy landscape paving.

Journal: Physical review letters20020211

Title: Structure of Met-enkephalin in explicit aqueous solution using replica exchange molecular dynamics.

Journal: Proteins20020201

Title: The biology of the opioid growth factor receptor (OGFr).

Journal: Brain research. Brain research reviews20020201

Title: Alteration in endogenous opioid systems due to chronic inflammatory pain conditions.

Journal: European journal of pharmacology20020125

Title: Evolutionary significance of different neurochemical organisation of the internal and external regions of auditory centres in the reptilian brain: an immunocytochemical and reduced NADPH-diaphorase histochemical study in turtles.

Journal: Brain research20020118

Title: Chronic exposure to the opioid growth factor, [Met5]-enkephalin, during pregnancy: maternal and preweaning effects.

Journal: Pharmacology, biochemistry, and behavior20020101

Title: [Selectivity of opioid peptide effects on excitability and various sensory inputs in LPl1 and PPl1 command neurons participating in defensive behavior of the snail Helix lucorum].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova20020101

Title: Uterus-innervating neurones of paracervical ganglion in the pig: immunohistochemical characteristics.

Journal: Folia morphologica20020101

Title: Consequences of intrauterine growth restriction on ventilatory and thermoregulatory responses to asphyxia and hypercapnia in the newborn guinea-pig.

Journal: Reproduction, fertility, and development20020101

Title: [Neurochemical organization of the turtle pretectum: immunohistochemical study. Comparative analysis].

Journal: Zhurnal evoliutsionnoi biokhimii i fiziologii20020101

Title: Transient arterial occlusion raises enkephalin in the canine sinoatrial node and improves vagal bradycardia.

Journal: Autonomic neuroscience : basic & clinical20011210

Title: Release of [Met5]enkephalin from the spinal cord by intraventricularly administered endomorphin-2, but not endomorphin-1 in the anesthetized rat.

Journal: Neuroscience letters20011204

Title: Reduced expression of neuropeptides can be related to respiratory disturbances in Rett syndrome.

Journal: Brain & development20011201

Title: Effects of opioid receptor activation on cardiovascular responses and extracellular monoamines within the rostral ventrolateral medulla during static contraction of skeletal muscle.

Journal: Neuroscience research20011201

Title: On-line preconcentration in capillary electrochromatography using a porous monolith together with solvent gradient and sample stacking.

Journal: Analytical chemistry20011115

Title: The neuropeptide FF analogue, 1DMe, acts as a functional opioid autoreceptor antagonist in the rat spinal cord.

Journal: European journal of pharmacology20011102

Title: Detection of nonderivatized peptides in capillary electrophoresis using quenched phosphorescence.

Journal: Analytical chemistry20011101

Title: Suprachiasmatic nucleus in the mouse: retinal innervation, intrinsic organization and efferent projections.

Journal: Brain research20011019

Title: The effect of methionine-enkephalin on nitric oxide release in mice is age and gender related.

Journal: Pharmacological research20011001

Title: Endorphin and enkephalin ameliorate excessive synovial cell functions in patients with rheumatoid arthritis.

Journal: The Journal of rheumatology20011001

Title: Delta opioid receptors inhibit vagal bradycardia in the sinoatrial node.

Journal: Journal of cardiovascular pharmacology and therapeutics20011001

Title: Differential antinociceptive effects induced by intrathecally administered endomorphin-1 and endomorphin-2 in the mouse.

Journal: European journal of pharmacology20010921

Title: Methionine-enkephalin-and Dynorphin A-release from immune cells and control of inflammatory pain.

Journal: Pain20010901

Title: Opioid and GABA receptors involved in mediation and modulation of tonic and stimulus-evoked inhibition of a spinal reflex in the decerebrated and spinalized rabbit.

Journal: Neuropharmacology20010901

Title: Naloxone blocks transferred preconditioning in isolated rabbit hearts.

Journal: Journal of molecular and cellular cardiology20010901

Title: Effects of beta-endorphin and met-enkephalin on platelet activity.

Journal: American journal of hematology20010901

Title: Methionine-enkephalin induces hyperglycemia through eyestalk hormones in the estuarine crab Scylla serrata.

Journal: The Biological bulletin20010801

Title: Pre- and postsynaptic inhibition by nociceptin in guinea pig small intestinal myenteric plexus in vitro.

Journal: American journal of physiology. Gastrointestinal and liver physiology20010701

Title: Colocalization of GABA, enkephalin and neuropeptide Y in the tectum of the green frog Rana esculenta.

Journal: Peptides20010701

Title: Met-enkephalin levels during PTCA-induced myocardial ischemia.

Journal: Peptides20010701

Title: Evidence for a hyperglycemic effect of methionine-enkephalin in the prawns Penaeus indicus and Metapenaeus monocerus.

Journal: General and comparative endocrinology20010701

Title: Temporal change of hippocampal enkephalin and dynorphin mRNA following trimethyltin intoxication in rats: effect of anticonvulsant.

Journal: Neuroscience letters20010629

Title: Unique responses of limbic met-enkephalin systems to low and high doses of methamphetamine.

Journal: Brain research20010629

Title: NO synthase inhibitors reduce opioid desensitization in rat locus coeruleus neurons in vitro.

Journal: Neuroreport20010613

Title: Antisera against endogenous opioids increase the nocifensive response to formalin: demonstration of inhibitory beta-endorphinergic control.

Journal: European journal of pharmacology20010601

Title: Transplacental transfer of the opioid growth factor, [Met(5)]-enkephalin, in rats.

Journal: Brain research bulletin20010601

Title: [Inhibition of ATP-activated current by met-Enk in isolated DRG neurons of the rat].

Journal: Sheng li xue bao : [Acta physiologica Sinica]20010601

Title: MEK inhibits secretin release and pancreatic secretion: roles of secretin-releasing peptide and somatostatin.

Journal: American journal of physiology. Gastrointestinal and liver physiology20010501

Title: Evidence that nitric oxide- and opioid-containing interneurons innervate vessels in the dorsal horn of the spinal cord of rats.

Journal: The Journal of physiology20010501

Title: Delta9-tetrahydrocannabinol releases and facilitates the effects of endogenous enkephalins: reduction in morphine withdrawal syndrome without change in rewarding effect.

Journal: The European journal of neuroscience20010501

Title: Effects of intracerebroventricularly administered chimeric peptide of metenkephalin and FMRFa--[D-Ala2]YFa-on antinociception and its modulation in mice.

Journal: Brain research bulletin20010501

Title: Involvement of pro-enkephalin-derived peptides in immunity.

Journal: Developmental and comparative immunology20010401

Title: Subcutaneous formalin enhances outflow of met-enkephalin- and cholecystokinin-like materials in the rat nucleus accumbens.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20010401

Title: Axon terminals containing CGRP-immunoreactivity form synapses with CRF- and Met-enkephalin-immunopositive neurons in the laterodorsal division of the bed nucleus of the stria terminalis in the rat.

Journal: Brain research20010302

Title: Anti-mitogenic action of opioid peptides on epidermal growth factor-stimulated uterine cells.

Journal: European journal of pharmacology20010302

Title: Withdrawal from alcohol in withdrawal seizure-prone and -resistant mice: evidence for enkephalin resistance.

Journal: Pharmacology, biochemistry, and behavior20010301

Title: Neutrophil neutral endopeptidase variation and its regulation by opioid peptides.

Journal: International immunopharmacology20010301

Title: Local opiate receptors in the sinoatrial node moderate vagal bradycardia.

Journal: Autonomic neuroscience : basic & clinical20010220

Title: Contrasting responses by basal ganglia met-enkephalin systems to low and high doses of methamphetamine in a rat model.

Journal: Journal of neurochemistry20010201

Title: Absence of spinal response to extracorporeal shock waves on the endogenous opioid systems in the rat.

Journal: Ultrasound in medicine & biology20010201

Title: Direct actions of cannabinoids on synaptic transmission in the nucleus accumbens: a comparison with opioids.

Journal: Journal of neurophysiology20010101

Title: [Non-adrenergic mechanisms of inhibition of the contractile activity of the cat small intestine by histamine, bradykinin, and met-enkephalin].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova20010101

Title: [The neuropeptide compensation for impared brain functions in the ascending row of mammals: interaction between the nervous and immune systems].

Journal: Fiziologiia cheloveka20010101

Title: Met-enkephalin is preferentially transported into the peripheral processes of primary afferent fibres in both control and HSV1-driven proenkephalin A overexpressing rats.

Journal: Neuroscience20010101

Title: Characterization of kappa and delta opioid receptors in isolated organs by using type/subtype selective agonists and antagonists.

Journal: Medical science monitor : international medical journal of experimental and clinical research20010101

Title: Effects of neonatal handling on nociceptin/orphanin FQ and opioid peptide levels in female rats.

Journal: Pharmacology, biochemistry, and behavior20010101

Title: An apparatus to assay opioid activity in the infused lumen of the intact isolated guinea pig ileum.

Journal: Journal of pharmacological and toxicological methods20010101

Title: On the mode of action of methionine enkephalin, FK 33-824 and naloxone in regulating the hemolymph glucose level in the fresh water field crab Oziotelphusa senex senex.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences20010101

Title: Protection of mice from malaria after co-administration of recombinant mouse granulocyte-macrophage colony- stimulating factor and methionine-enkephalin.

Journal: European cytokine network20010101

Title: Cytoprotective effects of met-enkephalin and alpha-MSH on ethanol induced gastric lesions in rats.

Journal: Journal of physiology, Paris20010101

Title: Modulation of fas/fasL in a murine retroviral infection by AZT and methionine enkephalin.

Journal: Advances in experimental medicine and biology20010101

Title: Ultrastructural co-localization of methionine enkephalin and neurotensin in the synapse of the cat stellate ganglia.

Journal: Proceedings of the Western Pharmacology Society20010101

Title: The role of met-enkephalin in silent myocardial ischemia in diabetic patients.

Journal: Journal of medicine20010101

Title: Receptor binding and G-protein activation by new Met5-enkephalin-Arg6-Phe7 derived peptides.

Journal: Life sciences20000218

Title: Delta-opioid receptor antagonist inhibits immunomodulation by Met-enkephalin analogs.

Journal: Neuroimmunomodulation19990101

Title: Oxytocin modulates glutamatergic synaptic transmission between cultured neonatal spinal cord dorsal horn neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience19980401

Title: Conformational analysis of [Met5]-enkephalin: solvation and ionization considerations.

Journal: Journal of computer-aided molecular design19980301

Title: The mu-opioid receptor antagonist D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP) [but not D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (CTAP)] produces a nonopioid receptor-mediated increase in K+ conductance of rat locus ceruleus neurons.

Journal: Molecular pharmacology19960901

Title: The cloned mu, delta and kappa receptors and their endogenous ligands: evidence for two opioid peptide recognition cores.

Journal: Brain research19951127

Title: Isolation and characterization of opioid peptides in the avian brain.

Journal: The Journal of experimental zoology19951001

Title: An endogenous aminoenkephalinase inhibitor: purification and characterization of Arg0-Met5-enkephalin from bovine striatum.

Journal: Journal of neurochemistry19941101

Title: Valproic acid-induced rapid changes of met-enkephalin levels in rat brain. Probable association with abstinence behavior and anticonvulsant activity.

Journal: Neuropeptides19940901

Title: Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.

Journal: Molecular pharmacology19940201

Title: Metabolism and transport of the pentapeptide metkephamid by brush-border membrane vesicles of rat intestine.

Journal: The Journal of pharmacy and pharmacology19940101

Title: Cloning and pharmacological characterization of a rat kappa opioid receptor.

Journal: Proceedings of the National Academy of Sciences of the United States of America19931101

Title: Kinetic parameters of antagonism by the delta opioid receptor selective peptide antagonist Boc-Tyr-Pro-Gly-Phe-Leu-Thr against selective and non-selective agonists in the mouse vas deferens.

Journal: Neuropeptides19930801

Title: Cloning and functional comparison of kappa and delta opioid receptors from mouse brain.

Journal: Proceedings of the National Academy of Sciences of the United States of America19930715

Title: Enkephalin antisense peptides: design, synthesis, and biological activity.

Journal: Pharmaceutical research19930501

Title: Comparative action of Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2 analogs on intestinal motility and nociception in rats.

Journal: The Journal of pharmacology and experimental therapeutics19930401

Title: In vivo modulation of gastrointestinal motor activity by Met-enkephalin, morphine and enkephalin analogs in chickens.

Journal: Regulatory peptides19930305

Title: [Approach to studying the structure-activity relationship of native peptides. I. Structural organization of the opioid peptide Tyr-Glu-Gly-Phe-Met-Arg-Gly-Leu and its artificial analogs].

Journal: Bioorganicheskaia khimiia19921201

Title: Feedback inhibition of met-enkephalin release from the rat spinal cord in vivo.

Journal: Synapse (New York, N.Y.)19920501

Title: Opioid control of the in vitro release of cholecystokinin-like material from the rat substantia nigra.

Journal: Journal of neurochemistry19920301

Title: A novel opioid structure which accepts protonated as well as non-protonated nitrogen: a family of pure, delta receptor selective antagonists.

Journal: Life sciences19920101

Title: [The role of the opiate mechanisms of the hippocampus and substantia nigra in the behavioral and convulsive disorders in picrotoxin-induced kindling].

Journal: Biulleten' eksperimental'noi biologii i meditsiny19910301

Title: Single potassium channels opened by opioids in rat locus ceruleus neurons.

Journal: Proceedings of the National Academy of Sciences of the United States of America19890501

Title: Antidiarrheal properties of supraspinal mu and delta and peripheral mu, delta and kappa opioid receptors: inhibition of diarrhea without constipation.

Journal: The Journal of pharmacology and experimental therapeutics19890401

Title: Monoclonal antibody against a peptide specified by [Met]-enkephalin complementary RNA recognizes the delta-class opioid receptor.

Journal: Immunology letters19890201

Title: Purification and assay of opioid activity of low molecular weight enkephalin-immunoreactive peptides generated by peptic digestion of rat plasma proteins.

Journal: Neuropeptides19890101

Title: Selectivity of various opioid peptides towards delta-, kappa; and mu-opioid receptors mediating presynaptic inhibition of neurotransmitter release in the brain.

Journal: Neuropeptides19890101

Title: Effect of enkephalin analogues Tyr-D-Ala-Gly-Phe-Cys(Et) and Tyr-D-Ala-Gly-Phe-Cys(Bu) on prolactin and growth hormone release in rats.

Journal: Endocrinologia experimentalis19881201

Title: Development of conformationally constrained linear peptides exhibiting a high affinity and pronounced selectivity for delta opioid receptors.

Journal: Journal of medicinal chemistry19881001

Title: Inhibition of exocrine pancreatic secretion by opiates is mediated by suppression of cholinergic transmission: characterization of receptor subtypes.

Journal: The Journal of pharmacology and experimental therapeutics19880701

Title: [D-Met2,Pro5] enkephalin [N1.5-beta-D-glucopyranosyl] amide: a glycosylpeptide with high antinociceptive activity.

Journal: International journal of peptide and protein research19880501

Title: [3H][D-Ser2(O-tert-butyl),Leu5]enkephalyl-Thr6 and [D-Ser2(O-tert-butyl),Leu5]enkephalyl-Thr6(O-tert-butyl). Two new enkephalin analogs with both a good selectivity and a high affinity toward delta-opioid binding sites.

Journal: The Journal of biological chemistry19880325

Title: Conformational analysis of possible biologically active (receptor-bound) conformations of peptides derived from cholecystokinin, cerulein and little gastrin and the opiate peptide, Met-enkephalin.

Journal: Peptides19880101

Title: [Biosynthesis of opioid peptides].

Journal: Annales d'endocrinologie19880101

Title: Potentiation of enkephalin action by peptidase inhibitors in rat locus ceruleus in vitro.

Journal: The Journal of pharmacology and experimental therapeutics19871001

Title: An approach to the multiple-minima problem in protein folding by relaxing dimensionality. Tests on enkephalin.

Journal: Journal of molecular biology19870805

Title: Mu and delta receptors belong to a family of receptors that are coupled to potassium channels.

Journal: Proceedings of the National Academy of Sciences of the United States of America19870801

Title: The effects of cortical ablation on multiple unit activity in the striatum following dexamphetamine.

Journal: Neuropharmacology19870801

Title: An acid-labile anchoring linkage for solid-phase synthesis of C-terminal peptide amides under mild conditions.

Journal: International journal of peptide and protein research19870801

Title: Enkephalins in the rat pituitary gland: immunohistochemical and biochemical observations.

Journal: Endocrinology19870701

Title: Mu opioid receptor involvement in enkephalin activation of dopamine neurons in the ventral tegmental area.

Journal: The Journal of pharmacology and experimental therapeutics19870401

Title: Audiogenic seizures during ethanol withdrawal can be blocked by a delta opioid agonist.

Journal: Drug and alcohol dependence19861201

Title: Kinetics of four 11C-labelled enkephalin peptides in the brain, pituitary and plasma of rhesus monkeys.

Journal: Regulatory peptides19861201

Title: Steady-state level and turnover rate of the tripeptide Tyr-Gly-Gly as indexes of striatal enkephalin release in vivo and their reduction during pentobarbital anesthesia.

Journal: Proceedings of the National Academy of Sciences of the United States of America19860801

Title: Enhancement of the generation of cytotoxic T cells by endogenous opiates.

Journal: Journal of neuroimmunology19860701

Title: Pharmacological properties of acetorphan, a parenterally active 'enkephalinase' inhibitor.

Journal: The Journal of pharmacology and experimental therapeutics19860601

Title: Metorphamide levels in chromaffin cells increase after treatment with reserpine.

Journal: Journal of neurochemistry19860501

Title: Specificity of the opioid affinity reagent, DALECK, in a set of isolated tissue assay systems.

Journal: Neuropeptides19860101

Title: Angiotensin-converting enzyme inhibitors potentiate the analgesic activity of [Met]-enkephalin-Arg6-Phe7 by inhibiting its degradation in mouse brain.

Journal: Molecular pharmacology19851201

Title: Receptors for opioid peptides in the guinea-pig ileum.

Journal: The Journal of pharmacology and experimental therapeutics19851101

Title: Modulation of striatal enkephalinergic neurons by antipsychotic drugs.

Journal: Federation proceedings19850601

Title: Proteolytic conversion of [Met]enkephalin-Arg6-Gly7-Leu8 by brain synaptic membranes. Characterization of formed peptides and mechanism of proteolysis.

Journal: The Journal of biological chemistry19850310

Title: Cardiovascular properties of metkephamid, a delta opioid receptor agonist, in man.

Journal: Clinical science (London, England : 1979)19850201

Title: Cardiovascular effects of intraventricular injection of FMRFamide, Met-enkephalin and their common analogues in the rat.

Journal: Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology19850101

Title: Catalepsy, hypermotility, increase of striatal acetylcholine release induced by morphine and Met-enkephalin as affected by prolonged hydrocortisone and ACTH treatment.

Journal: Polish journal of pharmacology and pharmacy19850101

Title: A new immunological approach to the detection and the quantitation of the Met5-enkephalin precursors in rat brain.

Journal: Neuropeptides19840901

Title: Alternative modes of enkephalin biosynthesis regulation by reserpine and cyclic AMP in cultured chromaffin cells.

Journal: Proceedings of the National Academy of Sciences of the United States of America19840701

Title: Nonspecific convulsions are induced by morphine but not D-Ala2-methionine-enkephalinamide at cortical sites.

Journal: Brain research19840507

Title: Sensitivity to morphine-evoked bradycardia in rats is modified by dynorphin (1-13), Leu- and Met-enkephalin.

Journal: The Journal of pharmacology and experimental therapeutics19840501

Title: Opioid-induced epileptogenic phenomena: anatomical, behavioral, and electroencephalographic features.

Journal: Annals of neurology19840401

Title: Effects of enkephalins and their analogs on gastric secretion.

Journal: Neuroscience and behavioral physiology19840101

Title: Metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain.

Journal: Proceedings of the National Academy of Sciences of the United States of America19831201

Title: Specific polyclonal antibodies to the carboxyl terminus of [Met]enkephalin-Arg6-Gly7-Leu8.

Journal: Archives of biochemistry and biophysics19830901

Title: Distribution of enkephalin-related peptides in rat brain: immunohistochemical studies using antisera to met-enkephalin and met-enkephalin Arg6Phe7.

Journal: Neuroscience19830701

Title: Tolerance to morphine bradycardia in the rat.

Journal: The Journal of pharmacology and experimental therapeutics19830701

Title: Interaction of naloxone with mu- and delta-opioid agonists on the respiration of rats.

Journal: European journal of pharmacology19830218

Title: Local and distal effects induced by unilateral striatal application of opiates in the absence or in the presence of naloxone on the release of dopamine in both caudate nuclei and substantiae nigrae of the cat.

Journal: Brain research19830110

Title: Blood pressure elevation in rats by peripheral administration of Tyr-Gly-Gly-Phe-Met-Arg-Phe and the invertebrate neuropeptide, Phe-Met-Arg-Phe-NH2.

Journal: Life sciences19821206

Title: Modulation of dopamine release in rat striatal slices by delta opiate agonists.

Journal: The Journal of pharmacology and experimental therapeutics19820801

Title: Mammalian neuronal actions of FMRFamide and the structurally related opioid Met-enkephalin-Arg6-Phe7.

Journal: Nature19820715

Title: Partial characterization of the mRNA that codes for enkephalins in bovine adrenal medulla and human pheochromocytoma.

Journal: Proceedings of the National Academy of Sciences of the United States of America19820101

Title: Proteolytic specificity of hemorrhage toxin a isolated from western diamondback rattlesnake (Crotalus atrox) venom.

Journal: Biochemistry19811124

Title: Evidence of the preferential involvement of mu receptors in analgesia using enkephalins highly selective for peripheral mu or delta receptors.

Journal: Journal of medicinal chemistry19811001

Title: Indication for central vagal endorphinergic control of heart rate in dogs.

Journal: European journal of pharmacology19810522

Title: Preliminary analysis of 1H and 13C spectral and relaxation behavior in methionine-enkephalin.

Journal: Proceedings of the National Academy of Sciences of the United States of America19760801

Title: Morphine-like peptides in mammalian brain: isolation, structure elucidation, and interactions with the opiate receptor.

Journal: Proceedings of the National Academy of Sciences of the United States of America19760701

Title: Identification of two related pentapeptides from the brain with potent opiate agonist activity.

Journal: Nature19751218

Title: Zhao D, et al. Methionine enkephalin, its role in immunoregulation and cancer therapy. Int Immunopharmacol. 2016 Feb 23. pii: S1567-5769(16)30050-9.

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