Title: Nephroprotective effect of GSK-3β inhibition by lithium ions and δ-opioid receptor agonist dalargin on gentamicin-induced nephrotoxicity.
Journal: Toxicology letters20130718
Title: Factors that restrict the cell permeation of cyclic prodrugs of an opioid peptide, part 4: Characterization of the biopharmaceutical and physicochemical properties of two new cyclic prodrugs designed to be stable to oxidative metabolism by cytochrome P-450 enzymes in the intestinal mucosa.
Journal: Journal of pharmaceutical sciences20120901
Title: Factors that restrict the cell permeation of cyclic prodrugs of an opioid peptide, part 3: Synthesis of analogs designed to have improved stability to oxidative metabolism.
Journal: Journal of pharmaceutical sciences20120901
Title: Protective effects of the delta opioid peptide [D-Ala2, D-Leu5]enkephalin in an ex vivo model of ischemia/reperfusion in brain slices.
Journal: CNS neuroscience & therapeutics20120901
Title: Effects of peripheral μ, δ, and Κ-opioid receptor agonists on the levels of anxiety and motor activity of rats.
Journal: Bulletin of experimental biology and medicine20120901
Title: Role of connexin-43 in protective PI3K-Akt-GSK-3β signaling in cardiomyocytes.
Journal: American journal of physiology. Heart and circulatory physiology20120615
Title: [DADLE suppresses the proliferation of human liver cancer HepG2 cells by activation of PKC pathway and elevates the sensitivity to cis-diammine dichloridoplatium].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology]20120601
Title: Genomic analysis of [d-Ala2, d-Leu5] enkephalin preconditioning in cortical neuron and glial cell injury after oxygen deprivation.
Journal: Brain research20120404
Title: Induction of torpor: mimicking natural metabolic suppression for biomedical applications.
Journal: Journal of cellular physiology20120401
Title: Development and in vivo characterization of a novel peptide drug delivery system providing extended plasma half life.
Journal: Journal of controlled release : official journal of the Controlled Release Society20120210
Title: Intensity of proliferative processes and degree of oxidative stress in the mucosa of the ileum in Crohn's disease.
Journal: Bulletin of experimental biology and medicine20120201
Title: Transport of the synthetic opioid peptide DADLE ([D-Ala2,D-Leu5]-enkephalin) in neuronal cells.
Journal: Journal of pharmaceutical sciences20120101
Title: [Effect of opioid peptides on oxygen-dependent microbicidity of peripheral blood neutrophils].
Journal: Fiziologiia cheloveka20120101
Title: Fluorescence spectroscopy studies of HEK293 cells expressing DOR-Gi1α fusion protein; the effect of cholesterol depletion.
Journal: Biochimica et biophysica acta20111201
Title: Activation of the δ-opioid receptor inhibits serum deprivation-induced apoptosis of human liver cells via the activation of PKC and the mitochondrial pathway.
Journal: International journal of molecular medicine20111201
Title: Effects of inhibitory amino acids on expression of GABAA Rα and glycine Rα1 in hypoxic rat cortical neurons during development.
Journal: Brain research20111124
Title: Mitochondrial ERK plays a key role in δ-opioid receptor neuroprotection against acute mitochondrial dysfunction.
Journal: Neurochemistry international20111101
Title: Morphine and remifentanil-induced cardioprotection: its experimental and clinical outcomes.
Journal: Korean journal of anesthesiology20111101
Title: Effect of peripheral administration of peptide ligands of δ-opioid receptors on anxiety level and locomotor activity of rats.
Journal: Bulletin of experimental biology and medicine20111001
Title: Astroglial reaction to delta opioid peptide [D-Ala2, D-Leu5] enkephalin confers neuroprotection against global ischemia in the adult rat hippocampus.
Journal: Neuroscience20110929
Title: Delta-opioid receptor activation prolongs respiratory motor output during oxygen-glucose deprivation in neonatal rat spinal cord in vitro.
Journal: Neuroscience20110728
Title: Evidence for two different broad-specificity oligopeptide transporters in intestinal cell line Caco-2 and colonic cell line CCD841.
Journal: American journal of physiology. Cell physiology20110601
Title: Opioids protect against substantia nigra cell degeneration under conditions of iron deprivation: a mechanism of possible relevance to the Restless Legs Syndrome (RLS) and Parkinson's disease.
Journal: Journal of the neurological sciences20110515
Title: Delta opioid peptide [D-Ala2, D-Leu5] enkephalin (DADLE) triggers postconditioning against transient forebrain ischemia.
Journal: European journal of pharmacology20110511
Title: Delayed administration of D-Ala2-D-Leu5-enkephalin, a delta-opioid receptor agonist, improves survival in a rat model of sepsis.
Journal: The Tohoku journal of experimental medicine20110501
Title: Kappa-opioid receptor activation during reperfusion limits myocardial infarction via ERK1/2 activation in isolated rat hearts.
Journal: Korean journal of anesthesiology20110501
Title: Effect of therapeutic hypothermia vs δ-opioid receptor agonist on post resuscitation myocardial function in a rat model of CPR.
Journal: Resuscitation20110301
Title: Transport of hepcidin, an iron-regulatory peptide hormone, into retinal pigment epithelial cells via oligopeptide transporters and its relevance to iron homeostasis.
Journal: Biochemical and biophysical research communications20110211
Title: Effects of dalargin on free radical processes in the blood of rats exposed to moderate hypothermia.
Journal: Bulletin of experimental biology and medicine20110101
Title: The influence of monovalent cations on trimeric G protein G(i)1α activity in HEK293 cells stably expressing DOR-G(i)1α (Cys(351)-Ile(351)) fusion protein.
Journal: Physiological research20110101
Title: Induction of an in vitro reversible hypometabolism through chitosan-based nanoparticles.
Journal: Journal of microencapsulation20110101
Title: Effects of casoxin 4 on morphine inhibition of small animal intestinal contractility and gut transit in the mouse.
Journal: Clinical and experimental gastroenterology20110101
Title: [A new approach to the evaluation of the state of the microcirculatory system in patients presenting with chronic atrophic pharyngitis and treated with a synthetic neuropeptide].
Journal: Vestnik otorinolaringologii20110101
Title: [Pancreatic functional status after wedge resection of the duodenal wall and para-pancreatic micro-irrigation].
Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology20110101
Title: Inhibition of glycogen synthase kinase 3beta prevents peroxide-induced collapse of mitochondrial membrane potential in rat ventricular myocytes.
Journal: Clinical and experimental pharmacology & physiology20100701
Title: Effects of intracerebroventricular application of the delta opioid receptor agonist [D-Ala2, D-Leu5] enkephalin on neurological recovery following asphyxial cardiac arrest in rats.
Journal: Neuroscience20100630
Title: Opioid peptides and opiate alkaloids in immunoregulatory processes.
Journal: Archives of medical science : AMS20100630
Title: Delta opioid peptide DADLE and naltrexone cause cell cycle arrest and differentiation in a CNS neural progenitor cell line.
Journal: Synapse (New York, N.Y.)20100401
Title: A GPCR/secretase complex regulates beta- and gamma-secretase specificity for Abeta production and contributes to AD pathogenesis.
Journal: Cell research20100201
Title: Excitatory and inhibitory effects of opioid agonists on respiratory motor output produced by isolated brainstems from adult turtles (Trachemys).
Journal: Respiratory physiology & neurobiology20100131
Title: Angiotensin II type 1 receptor-mediated upregulation of calcineurin activity underlies impairment of cardioprotective signaling in diabetic hearts.
Journal: Circulation research20100108
Title: Identification of a novel sodium-coupled oligopeptide transporter (SOPT2) in mouse and human retinal pigment epithelial cells.
Journal: Investigative ophthalmology & visual science20100101
Title: Dysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomes.
Journal: PloS one20100101
Title: [Regulatory peptides influence on hypoxia induced tooth germ pathology of new born albino rats].
Journal: Stomatologiia20100101
Title: [The study of peptide stability during hydrolysis by rat gastroenteric tract fragments].
Journal: Bioorganicheskaia khimiia20100101
Title: Endoplasmic reticulum stress in diabetic hearts abolishes erythropoietin-induced myocardial protection by impairment of phospho-glycogen synthase kinase-3beta-mediated suppression of mitochondrial permeability transition.
Journal: Diabetes20091201
Title: Delta-opioid receptor ligands in shock treatment.
Journal: Resuscitation20091101
Title: Delta opioid agonist [D-Ala2, D-Leu5] enkephalin (DADLE) reduced oxygen-glucose deprivation caused neuronal injury through the MAPK pathway.
Journal: Brain research20091006
Title: Role of opioid receptors in the reduction of formalin-induced secondary allodynia and hyperalgesia in rats.
Journal: European journal of pharmacology20091001
Title: Effects of opioid receptor activation on thermal antinociception in red-eared slider turtles (Trachemys scripta).
Journal: American journal of veterinary research20090901
Title: Regulation of interleukin-1beta and interleukin-8 production by agonists of mu and delta opiate receptors in vitro.
Journal: Neuroscience and behavioral physiology20090701
Title: Protein kinase C mediates the effects of delta-opioid receptor stimulation on survival and apoptosis in neonatal cardiomyocytes cultured in serum-deprived condition.
Journal: Die Pharmazie20090701
Title: A comparison of the effects of p-glycoprotein inhibitors on the blood-brain barrier permeation of cyclic prodrugs of an opioid peptide (DADLE).
Journal: Journal of pharmaceutical sciences20090601
Title: Functional identification of a novel transport system for endogenous and synthetic opioid peptides in the rabbit conjunctival epithelial cell line CJVE.
Journal: Pharmaceutical research20090501
Title: Gastroprotective effect of dalargin in gastropathy due to treatment with nonsteroid antiinflammatory drugs.
Journal: Bulletin of experimental biology and medicine20090401
Title: Neuroprotective role of delta-opioid receptors against mitochondrial respiratory chain injury.
Journal: Brain research20090203
Title: An ion pairing approach to increase the loading of hydrophilic and lipophilic drugs into PEGylated PLGA nanoparticles.
Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V20090201
Title: Factors that restrict the intestinal cell permeation of cyclic prodrugs of an opioid peptide (DADLE): Part I. Role of efflux transporters in the intestinal mucosa.
Journal: Journal of pharmaceutical sciences20090101
Title: Factors that restrict intestinal cell permeation of cyclic prodrugs of an opioid peptide (DADLE): Part II. Role of metabolic enzymes in the intestinal mucosa.
Journal: Journal of pharmaceutical sciences20090101
Title: Gz mediates the long-lasting desensitization of brain CB1 receptors and is essential for cross-tolerance with morphine.
Journal: Molecular pain20090101
Title: Hibernation-like state induced by an opioid peptide protects against experimental stroke.
Journal: BMC biology20090101
Title: delta-Opioid receptor activation attenuates oxidative injury in the ischemic rat brain.
Journal: BMC biology20090101
Title: Comparison and validation of drug loading parameters of PEGylated nanoparticles purified by a diafiltration centrifugal device and tangential flow filtration.
Journal: Drug development and industrial pharmacy20081201
Title: Delta-opioid receptors activate ERK/MAP kinase via integrin-stimulated receptor tyrosine kinases.
Journal: Cellular signalling20081201
Title: Inhibitory and excitatory effects of micro-, delta-, and kappa-opioid receptor activation on breathing in awake turtles, Trachemys scripta.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology20081101
Title: delta-Opioid receptors stimulate ERK1/2 activity in NG108-15 hybrid cells by integrin-mediated transactivation of TrkA receptors.
Journal: FEBS letters20081015
Title: Mu-opioid receptor in the nucleus submedius: involvement in opioid-induced inhibition of mirror-image allodynia in a rat model of neuropathic pain.
Journal: Neurochemical research20081001
Title: Differential effects of opioid agonists on G protein expression in CHO cells expressing cloned human opioid receptors.
Journal: Brain research bulletin20080905
Title: Evidence for a mu-delta opioid receptor complex in CHO cells co-expressing mu and delta opioid peptide receptors.
Journal: Peptides20080801
Title: [Effects of delta-opioid receptor stimulation on survival of cultured myocardial cells upon to serum deprivation].
Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology20080801
Title: [Regulation of IL-1beta and IL-8 production by mu-, delta-opiate receptors agonists in vitro].
Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova20080701
Title: CXCR2 chemokine receptor antagonism enhances DOP opioid receptor function via allosteric regulation of the CXCR2-DOP receptor heterodimer.
Journal: The Biochemical journal20080601
Title: Capillary electrophoresis chemiluminescent detection system equipped with a two-step postcolumn flow interface for detection of some enkephalin-related peptides labeled with acridinium ester.
Journal: Electrophoresis20080601
Title: Myocardial resistance to ischemic and reperfusion injuries under conditions of chronic administration of opioid receptor agonists and antagonists.
Journal: Bulletin of experimental biology and medicine20080601
Title: Assessment of the delta opioid agonist DADLE in a rat model of lethal hemorrhage treated by emergency preservation and resuscitation.
Journal: Resuscitation20080501
Title: delta-Opioid receptor stimulation enhances the growth of neonatal rat ventricular myocytes via the extracellular signal-regulated kinase pathway.
Journal: Clinical and experimental pharmacology & physiology20080101
Title: Effect of formulation factors on incorporation of the hydrophilic peptide dalargin into PLGA and mPEG-PLGA nanoparticles.
Journal: Biopolymers20080101
Title: [Cardiovascular effects of D-ALA2, LEU5, ARG6-enkephalin (dalargin) are mediated by peripheral mu-opioid receptor activation].
Journal: Eksperimental'naia i klinicheskaia farmakologiia20080101
Title: Development of a chitosan-based nanoparticle formulation for delivery of a hydrophilic hexapeptide, dalargin.
Journal: Biopolymers20080101
Title: The utility of oligopeptidase in brain-targeting delivery of an enkephalin analogue by prodrug design.
Journal: The open medicinal chemistry journal20080101
Title: Effects of delta-opioid receptor stimulation and inhibition on hippocampal survival in a rat model of forebrain ischaemia.
Journal: British journal of anaesthesia20071001
Title: Delta-opioid receptor activation before ischemia reduces gap junction permeability in ischemic myocardium by PKC-epsilon-mediated phosphorylation of connexin 43.
Journal: American journal of physiology. Heart and circulatory physiology20070901
Title: The delta-opioid receptor agonist DADLE at reperfusion protects the heart through activation of pro-survival kinases via EGF receptor transactivation.
Journal: American journal of physiology. Heart and circulatory physiology20070901
Title: Effect of dalargin on DNA synthesis in the gastric mucosa of albino rats.
Journal: Bulletin of experimental biology and medicine20070901
Title: Clofibrate and dalargin increase luminol-dependent chemiluminescence of mouse blood.
Journal: Bulletin of experimental biology and medicine20070901
Title: Dose-dependent neuroprotection of delta opioid peptide [D-Ala2, D-Leu5] enkephalin in neuronal death and retarded behavior induced by forebrain ischemia in rats.
Journal: Neuroscience letters20070816
Title: delta-, but not mu-, opioid receptor stabilizes K(+) homeostasis by reducing Ca(2+) influx in the cortex during acute hypoxia.
Journal: Journal of cellular physiology20070701
Title: Preconditioning-mimetics bradykinin and DADLE activate PI3-kinase through divergent pathways.
Journal: Journal of molecular and cellular cardiology20070401
Title: Delta opioid receptors stimulation with [D-Ala2, D-Leu5] enkephalin does not provide neuroprotection in the hippocampus in rats subjected to forebrain ischemia.
Journal: Neuroscience letters20070313
Title: Inhibition of agonist-induced down-regulation of the delta-opioid receptor with a proteasome inhibitor attenuates opioid tolerance in human embryonic kidney 293 cells.
Journal: The Journal of pharmacology and experimental therapeutics20070301
Title: Survivin mediates the anti-apoptotic effect of delta-opioid receptor stimulation in cardiomyocytes.
Journal: Journal of cell science20070301
Title: Roles of different subtypes of opioid receptors in mediating the ventrolateral orbital cortex opioid-induced inhibition of mirror-neuropathic pain in the rat.
Journal: Neuroscience20070223
Title: Cortical delta-opioid receptors potentiate K+ homeostasis during anoxia and oxygen-glucose deprivation.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism20070201
Title: The inhibitory effect of opioids on HepG2 cells is mediated via interaction with somatostatin receptors.
Journal: European journal of pharmacology20070119
Title: [Endocrine homeostasis and its correction with stress protectors in children with severe burn injury].
Journal: Anesteziologiia i reanimatologiia20070101
Title: Protective effects of a hibernation-inducer on hepatocyte injury induced by hypothermic preservation.
Journal: Journal of hepato-biliary-pancreatic surgery20070101
Title: Modifying ligand-induced and constitutive signaling of the human 5-HT4 receptor.
Journal: PloS one20070101
Title: [Regulated hypothermia after cardiac arrest. A glimpse into the future].
Journal: Der Anaesthesist20061201
Title: Effects of apolipoproteins on dalargin transport across the blood-brain barrier.
Journal: Bulletin of experimental biology and medicine20061201
Title: Role of hepatic opioid receptors in the regulation of bile excretion.
Journal: Bulletin of experimental biology and medicine20061101
Title: Naloxone-blocked depriming effect of anxiolytic selank on apomorphine-induced behavioral manifestations of hyperfunction of dopamine system.
Journal: Bulletin of experimental biology and medicine20061101
Title: Activation of ERK and suppression of calcineurin are interacting mechanisms of cardioprotection afforded by delta-opioid receptor activation.
Journal: Basic research in cardiology20060901
Title: The effect of the enkephalin DADLE on transcription does not depend on opioid receptors.
Journal: Histochemistry and cell biology20060801
Title: Diastereomeric differentiation of peptides with CuII and FeII complexation in an ion trap mass spectrometer.
Journal: Journal of mass spectrometry : JMS20060801
Title: [Influence of hydrocortisone and adrenaline against the background of mu- and delta-opiate receptors blockade on local immune response in mice].
Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova20060701
Title: Rapid hypoxia preconditioning protects cortical neurons from glutamate toxicity through delta-opioid receptor.
Journal: Stroke20060401
Title: mu- but not delta- and kappa-opioid receptors in the ventrolateral orbital cortex mediate opioid-induced antiallodynia in a rat neuropathic pain model.
Journal: Brain research20060303
Title: Localizing extracellular signal-regulated kinase (ERK) in pharmacological preconditioning's trigger pathway.
Journal: Basic research in cardiology20060301
Title: Effects of amino acid chirality and the chemical linker on the cell permeation characteristics of cyclic prodrugs of opioid peptides.
Journal: Journal of medicinal chemistry20060223
Title: delta opioid receptors stimulate Akt-dependent phosphorylation of c-jun in T cells.
Journal: The Journal of pharmacology and experimental therapeutics20060201
Title: DADLE induces a reversible hibernation-like state in HeLa cells.
Journal: Histochemistry and cell biology20060101
Title: [The role of monocytes in the effects of beta-endorphin and selective agonists of mu- and delta-Opiate receptors on the proliferative activity of peripheral blood lymphocytes].
Journal: Fiziologiia cheloveka20060101
Title: Bench-to-bedside review: potential strategies to protect or reverse mitochondrial dysfunction in sepsis-induced organ failure.
Journal: Critical care (London, England)20060101
Title: Induction of delta opioid receptor function by up-regulation of membrane receptors in mouse primary afferent neurons.
Journal: Molecular pharmacology20051201
Title: Significant differences in the disposition of cyclic prodrugs of opioid peptides in rats and guinea pigs following IV administration.
Journal: Journal of pharmaceutical sciences20051201
Title: Chronotropic effect of D-Ala2,Leu5,Arg6-enkephalin (dalargin) is associated with activation of peripheral kappa-opioid receptors.
Journal: Bulletin of experimental biology and medicine20051201
Title: System of hemopoiesis and morphogenesis.
Journal: Bulletin of experimental biology and medicine20051101
Title: Stability of oxymethyl-modified coumarinic acid cyclic prodrugs of diastereomeric opioid peptides in biological media from various animal species including human.
Journal: Journal of pharmaceutical sciences20051001
Title: A delta2-opioid agonist inhibits p38 MAPK and suppresses activation of murine macrophages.
Journal: The Journal of surgical research20050901
Title: Picomolar concentrations of hibernation induction delta opioid peptide [D-Ala2,D-Leu5]enkephalin increase the nerve growth factor in NG-108 cells.
Journal: Synapse (New York, N.Y.)20050901
Title: Analysis and separation of enkephalin and dalargin analogues and fragments by capillary zone electrophoresis.
Journal: Journal of chromatography. A20050715
Title: GABA and glycine are protective to mature but toxic to immature rat cortical neurons under hypoxia.
Journal: The European journal of neuroscience20050701
Title: Double-coated poly (butylcynanoacrylate) nanoparticulate delivery systems for brain targeting of dalargin via oral administration.
Journal: Journal of pharmaceutical sciences20050601
Title: delta-Opioid agonist induced regulation of E2F1 DNA binding activity in NG108-15 cells.
Journal: Brain research. Molecular brain research20050520
Title: Characterisation of opioid receptors involved in modulating circular and longitudinal muscle contraction in the rat ileum.
Journal: British journal of pharmacology20050301
Title: Fine electrophysiological analysis of impulse activity of various neuron types in nodose ganglion during intraatrial injection of dalargin.
Journal: Bulletin of experimental biology and medicine20050301
Title: [Regulation by opiod peptides of the antioxidant enzyme activity and the prostanoid system in myocardium during stress].
Journal: Biomeditsinskaia khimiia20050101
Title: [Transcranial electrostimulation combined with dalargin ultraphonophoresis in the treatment of patients with chronic idiopathic eczema].
Journal: Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury20050101
Title: Central effect of mu-opioid agonists on antral motility in conscious rats.
Journal: Brain research20041022
Title: Involvement of G protein betagamma-subunits in diverse signaling induced by G(i/o)-coupled receptors: study using the Xenopus oocyte expression system.
Journal: American journal of physiology. Cell physiology20041001
Title: Delta-opioid receptor antagonists exhibit properties of partial delta-receptor agonists in isolated perfused heart.
Journal: Bulletin of experimental biology and medicine20041001
Title: Delta opioid peptide (D-Ala 2, D-Leu 5) enkephalin: linking hibernation and neuroprotection.
Journal: Frontiers in bioscience : a journal and virtual library20040901
Title: Feeding responses to mu-, delta- and kappa-opioid receptor agonists in the meat-type chick.
Journal: Pharmacology, biochemistry, and behavior20040801
Title: Ultrastructural and immunocytochemical analyses of opioid treatment effects on PC3 prostatic cancer cells.
Journal: Microscopy research and technique20040615
Title: Differential effects of opioid peptides on myocardial ischemic tolerance.
Journal: The Journal of surgical research20040601
Title: Effect of protein kinases on lactate dehydrogenase activity in cortical neurons during hypoxia.
Journal: Brain research20040529
Title: Alternative strategy for stress tolerance: opioids.
Journal: The journals of gerontology. Series A, Biological sciences and medical sciences20040501
Title: [Protective effects of a delta-opioid-receptor agonist and an oxygen radical scavenger on postischemic hearts].
Journal: Herz20040501
Title: The effect of substitution patterns on the release rates of opioid peptides DADLE and [Leu(5)]-enkephalin from coumarin prodrug moieties.
Journal: Bioorganic chemistry20040401
Title: Opioid-mediated modulation of calcium currents in striatal and pallidal neurons following reserpine treatment: focus on kappa response.
Journal: Synapse (New York, N.Y.)20040301
Title: Effect of opiate peptide dalargin and des-Tyr-dalargin on cardiac pump function during ischemia-reperfusion.
Journal: Bulletin of experimental biology and medicine20040101
Title: Mu but not delta and kappa opioid receptor involvement in ventrolateral orbital cortex opioid-evoked antinociception in formalin test rats.
Journal: Neuroscience20040101
Title: [Effects of naloxone, nalorphine and dalargin on the course of shock due to the combination of mechanical trauma and acute blood loss].
Journal: Patologicheskaia fiziologiia i eksperimental'naia terapiia20040101
Title: Evidence for the involvement of an opioid system in sciatic nerve of Rana ridibunda.
Journal: Neuropeptides20040101
Title: Opioid modulation of GABA release in the rat inferior colliculus.
Journal: BMC neuroscience20040101
Title: [Correction of temperature homeostasis and microcirculation under the stress-protection anesthesia in hip replacement].
Journal: Anesteziologiia i reanimatologiia20040101
Title: [The effect of dalargin and des-Tyr-dalargin on the functional state of intact and ischemized-reperfused myocardium].
Journal: Eksperimental'naia i klinicheskaia farmakologiia20040101
Title: [Impaired blood coagulative properties in the early postresuscitation period and their prevention].
Journal: Anesteziologiia i reanimatologiia20040101
Title: [Role of NO-synthase in stimulation of opiate receptors and kidney oxidative stress resistance].
Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 )20040101
Title: A possible role for an enkephalinergic system in the internal defense mechanism of Biomphalaria alexandrina exposed to Schistosoma mansoni.
Journal: Journal of the Egyptian Society of Parasitology20031201
Title: [Endonasal electrophoresis of dalargin in the therapy of multiple and giant duodenal ulcers].
Journal: Likars'ka sprava20031201
Title: Convergent effects of oxytocin and a delta-opioid agonist in the bed nuclei of the stria terminalis of the peripartum rat.
Journal: Brain research20031121
Title: The first and third intracellular loops together with the carboxy terminal tail of the delta-opioid receptor contribute toward functional interaction with Galpha16.
Journal: Journal of neurochemistry20031101
Title: Effect of opioid receptor ligands on the mu-S196A knock-in and mu knockout mouse vas deferens.
Journal: European journal of pharmacology20031008
Title: Effects of endogenous and synthetic opioid peptides on neutrophil function in vitro.
Journal: British journal of anaesthesia20031001
Title: HL-1 myocytes exhibit PKC and K(ATP) channel-dependent delta opioid preconditioning.
Journal: The Journal of surgical research20031001
Title: [D-Ala2, D-Leu5] enkephalin (DADLE) protects liver against ischemia-reperfusion injury in the rat.
Journal: The Journal of surgical research20030901
Title: Improved brain uptake and pharmacological activity of dalargin using a peptide-vector-mediated strategy.
Journal: The Journal of pharmacology and experimental therapeutics20030701
Title: Contribution of organic anion transporting polypeptide OATP-C to hepatic elimination of the opioid pentapeptide analogue [D-Ala2, D-Leu5]-enkephalin.
Journal: The Journal of pharmacy and pharmacology20030701
Title: A truncated delta opioid receptor, spontaneously produced in human but not rat neuroblastoma cells, interferes with signaling of the full-length receptor.
Journal: Neuroscience letters20030619
Title: Role of kappa-opioid receptor activation in pharmacological preconditioning of swine.
Journal: American journal of physiology. Heart and circulatory physiology20030601
Title: Peripheral opioidergic regulation of the tracheobronchial mucociliary transport system.
Journal: Journal of applied physiology (Bethesda, Md. : 1985)20030601
Title: Effect of a delta receptor agonist on duration of survival during hemorrhagic shock.
Journal: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine20030601
Title: Promiscuous coupling at receptor-Galpha fusion proteins. The receptor of one covalent complex interacts with the alpha-subunit of another.
Journal: The Journal of biological chemistry20030502
Title: delta-Opioid receptors exhibit high efficiency when activating trimeric G proteins in membrane domains.
Journal: Journal of neurochemistry20030401
Title: New development in the tritium labelling of peptides and proteins using solid catalytic isotopic exchange with spillover-tritium.
Journal: Amino acids20030401
Title: Chronic [D-Ala2, D-Leu5]enkephalin treatment increases the nerve growth factor in adult mouse brain.
Journal: European journal of pharmacology20030319
Title: Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles.
Journal: Pharmaceutical research20030301
Title: Phosphorylation of activating transcription factor in murine splenocytes through delta opioid receptors.
Journal: Cellular immunology20030201
Title: Squirreling away at Parkinson's.
Journal: Drug discovery today20030115
Title: Mechanisms of opioid delta (delta) and kappa ( kappa) receptors' cardioprotection in ischaemic preconditioning in a rat model of myocardial infarction.
Journal: Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners20030101
Title: [Prevention of altering effects of surgical stress in children with abdominal pathology].
Journal: Anesteziologiia i reanimatologiia20030101
Title: Fully detachable molecular umbrellas as peptide delivery agents.
Journal: Bioconjugate chemistry20030101
Title: Chronic morphine treatment inhibits opioid receptor desensitization and internalization.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20021201
Title: Quantitative analysis of a model opioid peptide and its cyclic prodrugs in rat plasma using high-performance liquid chromatography with fluorescence and tandem mass spectrometric detection.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20021125
Title: Opioid receptor subtypes differentially modulate serotonin efflux in the rat central nervous system.
Journal: The Journal of pharmacology and experimental therapeutics20021101
Title: In vitro stability and in vivo pharmacokinetic studies of a model opioid peptide, H-Tyr-D-Ala-Gly-Phe-D-Leu-OH (DADLE), and its cyclic prodrugs.
Journal: The Journal of pharmacology and experimental therapeutics20021101
Title: Evaluation of the permeation characteristics of a model opioid peptide, H-Tyr-D-Ala-Gly-Phe-D-Leu-OH (DADLE), and its cyclic prodrugs across the blood-brain barrier using an in situ perfused rat brain model.
Journal: The Journal of pharmacology and experimental therapeutics20021101
Title: A pH-sensitive fluor, CypHer 5, used to monitor agonist-induced G protein-coupled receptor internalization in live cells.
Journal: BioTechniques20021101
Title: Peptide washout and permeability from glyceryl monooleate buccal delivery systems.
Journal: Drug development and industrial pharmacy20021001
Title: Gyrus cinguli transection abolishes delta-opioid receptor-induced gastroprotection and alters alpha 2 adrenoceptor activity in the lower brainstem in rats.
Journal: Brain research20020823
Title: Neuroprotective role of delta-opioid receptors in cortical neurons.
Journal: American journal of physiology. Cell physiology20020601
Title: Role of delta-opioid receptor agonists on infarct size reduction in swine.
Journal: American journal of physiology. Heart and circulatory physiology20020601
Title: Delta opiates increase ischemic tolerance in isolated rabbit jejunum.
Journal: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine20020601
Title: Characterization of the efflux transporter(s) responsible for restricting intestinal mucosa permeation of an acyloxyalkoxy-based cyclic prodrug of the opioid peptide DADLE.
Journal: Pharmaceutical research20020601
Title: Characterization of the efflux transporter(s) responsible for restricting intestinal mucosa permeation of the coumarinic acid-based cyclic prodrug of the opioid peptide DADLE.
Journal: Pharmaceutical research20020601
Title: A modified coumarinic acid-based cyclic prodrug of an opioid peptide: its enzymatic and chemical stability and cell permeation characteristics.
Journal: Pharmaceutical research20020601
Title: The effect of enzyme inhibitor and absorption site following [D-ala2, D-leu5]enkephalin oral administration in rats.
Journal: Biopharmaceutics & drug disposition20020501
Title: Angiotensin 1-9 and 1-7 release in human heart: role of cathepsin A.
Journal: Hypertension (Dallas, Tex. : 1979)20020501
Title: Correction of L-NAME-induced disturbances in DNA synthesis and free radical oxidation in respiratory organs of newborn albino rats with dalargin.
Journal: Bulletin of experimental biology and medicine20020501
Title: Synthesis and conformational analysis of a coumarinic acid-based cyclic prodrug of an opioid peptide with modified sensitivity to esterase-catalyzed bioconversion.
Journal: The journal of peptide research : official journal of the American Peptide Society20020401
Title: Involvement of opioid delta (delta)- and kappa (kappa)-receptors in ischemic preconditioning in a rat model of myocardial infarction.
Journal: Methods and findings in experimental and clinical pharmacology20020401
Title: Receptor specificity of the antiarrhythmic effect produced by opioid peptides Dalargin and DADLE during myocardial reperfusion.
Journal: Bulletin of experimental biology and medicine20020401
Title: Crystal structure of biphalin sulfate: a multireceptor opioid peptide.
Journal: The journal of peptide research : official journal of the American Peptide Society20020301
Title: Antiapoptotic and cytotoxic properties of delta opioid peptide [D-Ala(2),D-Leu(5)]enkephalin in PC12 cells.
Journal: Synapse (New York, N.Y.)20020101
Title: A critical protein kinase C phosphorylation site on the 5-HT(1A) receptor controlling coupling to N-type calcium channels.
Journal: The Journal of physiology20020101
Title: Delta opioid activation of the mitogen-activated protein kinase cascade does not require transphosphorylation of receptor tyrosine kinases.
Journal: BMC pharmacology20020101
Title: [Application of synthetic neuropeptides in complex of surgical treatment of acute pancreatitis and its complication].
Journal: Klinichna khirurhiia20020101
Title: [Antioxidant system in rat tissues in hypothermia and dalargin introduction].
Journal: Voprosy meditsinskoi khimii20020101
Title: [Clinical response to agonists of mu and beta opiate receptors in patients with ischemic heart disease: effects of D-Ala2-Leu5-Arg6-enkephalin on hemodynamics, oxygen balance and lipid spectrum of blood].
Journal: Klinicheskaia meditsina20020101
Title: [Effect of peripheral opiate receptor agonist dalargin on exercise tolerance in patients with coronary and peripheral arteries atherosclerosis].
Journal: Fiziologiia cheloveka20020101
Title: [Effect of dalargin on the bile acid spectrum in human bile].
Journal: Likars'ka sprava20020101
Title: [Effect of dalarginum on the level of nitric oxide stable metabolites in rat kidneys during apoptosis activation].
Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 )20020101
Title: Disassembly of nuclear bodies during arousal from hibernation: an in vitro study.
Journal: Chromosoma20011201
Title: Effects of central opiate and serotoninergic structures on heart rhythm during acute myocardial ischemia.
Journal: Bulletin of experimental biology and medicine20011201
Title: Dependence of delta1-opioid receptor-induced cardioprotection on a tyrosine kinase-dependent but not a Src-dependent pathway.
Journal: The Journal of pharmacology and experimental therapeutics20011101
Title: Myocardial protection by ischemic preconditioning and delta-opioid receptor activation in the isolated working rat heart.
Journal: The Journal of thoracic and cardiovascular surgery20011101
Title: Opioid preconditioning: myocardial function and energy metabolism.
Journal: The Annals of thoracic surgery20011101
Title: Hibernation-induction peptide and cell death: [D-Ala2,D-Leu5]enkephalin blocks Bax-related apoptotic processes.
Journal: European journal of pharmacology20010928
Title: Control of the efficiency of agonist-induced information transfer and stability of the ternary complex containing the delta opioid receptor and the alpha subunit of G(i1) by mutation of a receptor/G protein contact interface.
Journal: Neuropharmacology20010901
Title: Opioid effects on glucose and eicosanoid metabolism in isolated uterus of ovariectomized and non-ovariectomized restricted diet rats.
Journal: Prostaglandins, leukotrienes, and essential fatty acids20010901
Title: Major difference in the expression of delta- and mu-opioid receptors between turtle and rat brain.
Journal: The Journal of comparative neurology20010723
Title: Identification of delta- and mu-type opioid receptors on human and murine dendritic cells.
Journal: Journal of neuroimmunology20010702
Title: Rostral ventrolateral medullary opioid receptor subtypes in the inhibitory effect of electroacupuncture on reflex autonomic response in cats.
Journal: Autonomic neuroscience : basic & clinical20010620
Title: Supraspinal delta- and mu-opioid receptors mediate gastric mucosal protection in the rat.
Journal: The Journal of pharmacology and experimental therapeutics20010601
Title: Interaction of poly(butylcyanoacrylate) nanoparticles with the blood-brain barrier in vivo and in vitro.
Journal: Journal of drug targeting20010601
Title: Opioids suppress basal and nicotine-induced catecholamine secretion via a stabilizing effect on actin filaments.
Journal: Endocrinology20010501
Title: The activation of mu opioid receptors promotes a small modulation of calcium currents in rat pallidal neurons.
Journal: Brain research20010406
Title: Characterization of opioid receptors modulating neurogenic contractions of circular muscle from porcine ileum and evidence that delta- and kappa-opioid receptors are coexpressed in myenteric neurons.
Journal: The Journal of pharmacology and experimental therapeutics20010401
Title: Delta opioid peptide [D-Ala2, D-Leu5]enkephalin causes a near complete blockade of the neuronal damage caused by a single high dose of methamphetamine: examining the role of p53.
Journal: Synapse (New York, N.Y.)20010315
Title: Essential activation of PKC-delta in opioid-initiated cardioprotection.
Journal: American journal of physiology. Heart and circulatory physiology20010301
Title: The human delta opioid receptor activates G(i1)alpha more efficiently than G(o1)alpha.
Journal: Journal of neurochemistry20010301
Title: Oxidative modification of plasma proteins during hypothermia and after dalargin administration.
Journal: Bulletin of experimental biology and medicine20010301
Title: Effects of opiate receptor ligands on DNA synthesis in tracheal epitheliocytes and smooth muscle cells of newborn albino rats.
Journal: Bulletin of experimental biology and medicine20010201
Title: Kappa- but not delta-opioid receptors mediate effects of ischemic preconditioning on both infarct and arrhythmia in rats.
Journal: American journal of physiology. Heart and circulatory physiology20010101
Title: Delta opioid peptide augments functional effects and intrastriatal graft survival of rat fetal ventral mesencephalic cells.
Journal: Cell transplantation20010101
Title: Characterization of kappa and delta opioid receptors in isolated organs by using type/subtype selective agonists and antagonists.
Journal: Medical science monitor : international medical journal of experimental and clinical research20010101
Title: Opioid receptor stimulation acts as mediator of protection in ischaemic preconditioning.
Journal: Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners20010101
Title: An apparatus to assay opioid activity in the infused lumen of the intact isolated guinea pig ileum.
Journal: Journal of pharmacological and toxicological methods20010101
Title: Activation of central opioid receptors may induce gastric mucosal defence in the rat.
Journal: Journal of physiology, Paris20010101
Title: Neonatal monosodium glutamate treatment abolishes both delta opioid receptor-induced and alpha-2 adrenoceptor-mediated gastroprotection in the lower brainstem in rats.
Journal: Journal of physiology, Paris20010101
Title: Receptorphin: a conserved peptide derived from the sequence of the opioid receptor, with opioid displacement activity and potent antiproliferative actions in tumor cells.
Journal: BMC pharmacology20010101
Title: Opioid peptides alleviated while naloxone potentiated methamphetamine-induced striatal dopamine depletion in mice.
Journal: Journal of neural transmission (Vienna, Austria : 1996)20010101
Title: [State of the opioid system in rats with different sensitivity to ethanol].
Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 )20010101
Title: Characterization of delta-opioid receptors and effect of enkephalins on IRD 98 rat epithelial intestinal cell line.
Journal: Pflugers Archiv : European journal of physiology20000301
Title: Delta opioid peptide [D-Ala2,D-leu5]enkephalin blocks the long-term loss of dopamine transporters induced by multiple administrations of methamphetamine: involvement of opioid receptors and reactive oxygen species.
Journal: The Journal of pharmacology and experimental therapeutics19981001
Title: Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
Journal: NIDA research monograph19980301
Title: Affinity labelling of frog brain opioid receptors by dynorphin(1-10) chloromethyl ketone.
Journal: Neuropeptides19970201
Title: [The realization of food-acquisition behavior in rats against a background of multiple injections of enkephalin-like peptides into the neostriatum].
Journal: Fiziologicheskii zhurnal imeni I.M. Sechenova19960101
Title: Conserved delta-activity in reverse enantiomeric opioid peptide.
Journal: Life sciences19950101
Title: Amino acids and peptides. XXII. Preparation and antinociceptive effect of [D-Ala2]Leu-enkephalin-poly(ethylene glycol) hybrid.
Journal: Biological & pharmaceutical bulletin19940601
Title: Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.
Journal: Molecular pharmacology19940201
Title: Kinetic parameters of antagonism by the delta opioid receptor selective peptide antagonist Boc-Tyr-Pro-Gly-Phe-Leu-Thr against selective and non-selective agonists in the mouse vas deferens.
Journal: Neuropeptides19930801
Title: Up-regulation of delta opioid receptors in neuroblastoma hybrid cells: evidence for differences in the mechanisms of action of sodium butyrate and naltrexone.
Journal: The Journal of pharmacology and experimental therapeutics19911001
Title: Binding to opioid receptors of enkephalin derivatives taking alpha-helical conformation and its dimer.
Journal: International journal of peptide and protein research19911001
Title: A monoclonal anti-idiotypic antibody to mu and delta opioid receptors.
Journal: Brain research. Molecular brain research19910301
Title: Modulation of the antinociceptive effect of morphine by casomorphin derivatives.
Journal: Biomedica biochimica acta19910101
Title: Influence of peptidase inhibitors on the apparent agonist potency of delta selective opioid peptides in vitro.
Journal: Life sciences19910101
Title: Different profile of electrocortical power spectrum changes after micro-infusion into the locus coeruleus of selective agonists at various opioid receptor subtypes in rats.
Journal: British journal of pharmacology19901101
Title: [Bioavailability of dalargin and its metabolism during intranasal administration to rats].
Journal: Biulleten' eksperimental'noi biologii i meditsiny19880701
Title: Morphine and enkephalins potently inhibit [3H]noradrenaline release from rat brain cortex synaptosomes: further evidence for a presynaptic localization of mu-opioid receptors.
Journal: Journal of neurochemistry19870401
Title: Opioid peptides. Biological study of [D-MetO2] dermorphin analogues in relation to the plurality of opioid receptors. XI.
Journal: Il Farmaco; edizione scientifica19870201
Title: Increased responsiveness to glucoregulatory effect of opiates in obese-diabetic ob/ob mice.
Journal: Diabetologia19870101
Title: Audiogenic seizures during ethanol withdrawal can be blocked by a delta opioid agonist.
Journal: Drug and alcohol dependence19861201
Title: Opiate-induced seizures: a study of mu and delta specific mechanisms.
Journal: Experimental neurology19860801
Title: [Study of peptide degradation in the serum by 1H-NMR].
Journal: Bioorganicheskaia khimiia19860101
Title: Mu- and delta-opioid receptor-mediated epileptoid responses in morphine-dependent and non-dependent rats.
Journal: Electroencephalography and clinical neurophysiology19851201
Title: Receptors for opioid peptides in the guinea-pig ileum.
Journal: The Journal of pharmacology and experimental therapeutics19851101
Title: Conformationally restricted analogs of somatostatin with high mu-opiate receptor specificity.
Journal: Proceedings of the National Academy of Sciences of the United States of America19850101
Title: Somatostatin analogs with affinity for opiate receptors in rat brain binding assay.
Journal: Peptides19850101
Title: A comparative study in rats of the respiratory depression and analgesia induced by mu- and delta-opioid agonists.
Journal: European journal of pharmacology19840316
Title: Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors.
Journal: Proceedings of the National Academy of Sciences of the United States of America19831001
Title: Plasma catecholamine and cardiovascular responses to morphine and D-ala2-d-leu5-enkephalin in conscious rats.
Journal: Archives internationales de pharmacodynamie et de therapie19831001
Title: Inhibition of an opioid-evoked vagal reflex in rats by naloxone, SMS 201-995 and ICI 154, 129.
Journal: Regulatory peptides19830701
Title: Multiple opiate binding sites in the central nervous system of the rabbit. Large predominance of a mu subtype in the cerebellum and characterization of a kappa subtype in the thalamus.
Journal: Molecular pharmacology19830701
Title: Interaction of naloxone with mu- and delta-opioid agonists on the respiration of rats.
Journal: European journal of pharmacology19830218
Title: Differential cardiovascular effects of mu, delta and kappa opiate agonists at discrete hypothalamic sites in the anesthetized rat.
Journal: Life sciences19821101
Title: Opioid pharmacology in the rat hippocampal slice.
Journal: Life sciences19821101
Title: Pharmacological characterization of opioid effects in the rat hippocampal slice.
Journal: The Journal of pharmacology and experimental therapeutics19821101
Title: Evidence of the preferential involvement of mu receptors in analgesia using enkephalins highly selective for peripheral mu or delta receptors.
Journal: Journal of medicinal chemistry19811001
Title: Specific protection of the binding sites of D-Ala2-D-Leu5-enkephalin (delta-receptors) and dihydromorphine (mu-receptors).
Journal: Proceedings of the Royal Society of London. Series B, Biological sciences19790831
Title: The inhibitory effects of presynaptic alpha-adrenoceptor agonists on contractions of guinea-pig ileum and mouse vas deferens in the morphine-dependent and withdrawn states produced in vitro.
Journal: British journal of pharmacology19790801
