Name: Name:1,3-bis(propan-2-yl) 2-(2H-1,3-dithiol-2-ylidene)propanedioate
Brand: AABLOCKS
SKU: AA00EACW
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00EACW

Chemical Name: 1,3-bis(propan-2-yl) 2-(2H-1,3-dithiol-2-ylidene)propanedioate

CAS Number: 59937-28-9

Molecular Formula: C12H16O4S2

Molecular Weight: 288.3830

MDL Number: MFCD00867646

SMILES: CC(OC(=O)C(=C1SC=CS1)C(=O)OC(C)C)C

Properties

BP: 321.5°C at 760 mmHg

Form: Solid

MP: 60.5°

Refractive Index: 1.4950 (estimate)

Storage: Keep in dry area;2-8℃;

Complexity: 363

Covalently-Bonded Unit Count: 1

Heavy Atom Count: 18

Hydrogen Bond Acceptor Count: 6

Rotatable Bond Count: 6

XLogP3: 3.8

Literature fold

Title: Physicochemical and pharmacokinetic characterization of a spray-dried malotilate emulsion.

Journal: International journal of pharmaceutics20110729

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Title: Matrix metalloproteinase gene delivery for liver fibrosis.

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Title: Serum levels of YKL-40 and PIIINP as prognostic markers in patients with alcoholic liver disease.

Journal: Journal of hepatology20030801

Title: [Effect of tanshinone IIA on CCl4-induced liver fibrosis in rats].

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Title: Gene-CYP11B2 expression in rat liver in hepatic fibrogenesis induced by CCl4.

Journal: Chinese medical journal20010101

Title: Modulation of the reductive metabolism of halothane by microsomal cytochrome b5 in rat liver.

Journal: Biochimica et biophysica acta19871207

Title: [Protective effect of malotilate (diisopropyl 1,3-dithiol-2-ylidenemalonate) on chemical-induced hepatotoxicity].

Journal: The Journal of toxicological sciences19860801

Title: Matsuda Y, et al. Effects of malotilate on alcoholic liver injury in rats. Alcohol Clin Exp Res. 1988;12(5):665-670.

Title: Vermeer MA, Wilson JH, Zijlstra FJ, Vincent JE. Differential effects of malotilate on 5-, 12- and 15-lipoxygenase in human ascites cells. Agents Actions. 1989;26(1-2):252-253.

Title: Poeschl A, et al. Malotilate reduces collagen synthesis and cell migration activity of fibroblasts in vitro. Biochem Pharmacol. 1987;36(22):3957-3963.

Title: Zijlstra FJ, et al. Differential effects of malotilate on 5-, 12- and 15-lipoxygenase in human ascites cells. Eur J Pharmacol. 1989;159(3):291-295.

Title: Wakasugi J, et al. Action of malotilate on reduced serum cholesterol level in rats with carbon tetrachloride-induced liver damage. Jpn J Pharmacol. 1985;38(4):391-401.

59937-28-9 | 1,3-bis(propan-2-yl) 2-(2H-1,3-dithiol-2-ylidene)propanedioate