[1]Duncton,MatthewA.J.;Roffey,JonathanR.A.;Hamlyn,RichardJ.;Adams,DavidR.[TetrahedronLetters,2006,vol.47,#15,p.2549-2552]
[2]CurrentPatentAssignee:MITSUBISHICHEMICALHOLDINGSCORPORATION-EP3381904,2018,A1Locationinpatent:Paragraph0157-0158
[1]Locationinpatent:experimentalpartQian,Kevin;Lian,Wang;Cywin,CharlesL.;Farmer,BennettT.;Hickey,Eugene;Homon,Carol;Jakes,Scottm;Kashem,MohammedA.;Lee,George;Leonard,Scott;Jun,Li;Magboo,Ronald;Wang,Mao;Pack,Edward;Peng,Charlene;Prokopowicz,Anthony;Welzel,Morgan;Wolak,John;Morwick,Tina[JournalofMedicinalChemistry,2009,vol.52,#7,p.1814-1827]
[1]Patent:EP3381904,2018,A1.Locationinpatent:Paragraph0157-0158
Title: 5-HT(2A) receptor blockade and 5-HT(2C) receptor activation interact to reduce cocaine hyperlocomotion and Fos protein expression in the caudate-putamen.
Journal: Synapse (New York, N.Y.) 20121201
Title: 5-HT2C receptor agonists attenuate pain-related behaviour in a rat model of trigeminal neuropathic pain.
Journal: European journal of pain (London, England) 20101101
Title: Spontaneous rhythmogenic capabilities of sympathetic neuronal assemblies in the rat spinal cord slice.
Journal: Neuroscience 20101027
Title: Stimulation of medial prefrontal cortex serotonin 2C (5-HT(2C)) receptors attenuates cocaine-seeking behavior.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100901
Title: Locomotor response to L-DOPA in reserpine-treated rats following central inhibition of aromatic L-amino acid decarboxylase: further evidence for non-dopaminergic actions of L-DOPA and its metabolites.
Journal: Neuroscience research 20100901
Title: Discriminative stimulus effects of serotonin agonists, neutral antagonists, and inverse agonists in pigeons: perspectives on intrinsic efficacy measurements in vivo.
Journal: Psychopharmacology 20100801
Title: Functional characteristics of serotonin 5-HT2A and 5-HT2C receptors in the brain and the expression of the 5-HT2A and 5-HT2C receptor genes in aggressive and non-aggressive rats.
Journal: Neuroscience and behavioral physiology 20100501
Title: Acquisition session length modulates consolidation effects produced by 5-HT2C ligands in a mouse autoshaping-operant procedure.
Journal: Behavioural pharmacology 20100301
Title: Impact of RNA editing on functions of the serotonin 2C receptor in vivo.
Journal: Frontiers in neuroscience 20100101
Title: Novel approach to data analysis in cocaine-conditioned place preference.
Journal: Behavioural pharmacology 20091201
Title: Physical binding pocket induction for affinity prediction.
Journal: Journal of medicinal chemistry 20091008
Title: Implication of the 5-HT2A and 5-HT2C (but not 5HT1A) receptors located within the periaqueductal gray in the elevated plus-maze test-retest paradigm in mice.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20091001
Title: Characterizing the effects of 5-HT(2C) receptor ligands on motor activity and feeding behaviour in 5-HT(2C) receptor knockout mice.
Journal: Neuropharmacology 20090901
Title: PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090603
Title: [Functional correlates of the brain 5-HT2A and 5-HT2C serotonin receptors and expression of 5-HT2A AND 5-HT2C genes in aggressive and nonaggressive Norway rats].
Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20090201
Title: Stimulation of 5-HT2C receptors attenuates cue and cocaine-primed reinstatement of cocaine-seeking behavior in rats.
Journal: Behavioural pharmacology 20071201
Title: Possible involvement of spinal noradrenergic mechanisms in the antiallodynic effect of intrathecally administered 5-HT2C receptor agonists in the rats with peripheral nerve injury.
Journal: European journal of pharmacology 20070712
Title: Activation of nucleus tractus solitarius 5-HT2A but not other 5-HT2 receptor subtypes inhibits the sympathetic activity in rats.
Journal: The European journal of neuroscience 20070701
Title: Different serotonin receptor agonists have distinct effects on sound-evoked responses in inferior colliculus.
Journal: Journal of neurophysiology 20061101
Title: Effect of 5HT2C-receptor agonist MK-212 on blood corticosterone level and behavior in mice.
Journal: Bulletin of experimental biology and medicine 20061101
Title: 5-HT receptor subtypes involved in the anxiogenic-like action and associated Fos response of acute fluoxetine treatment in rats.
Journal: Psychopharmacology 20060401
Title: Pharmacological characterization of 5-hydroxytryptamine-induced contraction in the chicken gastrointestinal tract.
Journal: Autonomic & autacoid pharmacology 20060401
Title: Serotonin2C receptors (5-HT2C R) control expression of cocaine-induced conditioned hyperactivity.
Journal: Drug and alcohol dependence 20060227
Title: Chronic treatment with a serotonin(2) receptor (5-HT(2)R) agonist modulates the behavioral and cellular response to (+)-3,4-methylenedioxymethamphetamine [(+)-MDMA].
Journal: Drug and alcohol dependence 20060201
Title: Administration of SCH 23390 into the medial prefrontal cortex blocks the expression of MDMA-induced behavioral sensitization in rats: an effect mediated by 5-HT2C receptor stimulation and not by D1 receptor blockade.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20051201
Title: Selective and nonselective serotonin antagonists block the aversive stimulus properties of MK212 and m-chlorophenylpiperazine (mCPP) in mice.
Journal: Neuropharmacology 20051201
Title: Behavioral effects of systemically administered MK-212 are prevented by ritanserin microinfusion into the basolateral amygdala of rats exposed to the elevated plus-maze.
Journal: Psychopharmacology 20051101
Title: Serotonin 5-HT2 receptors induce a long-lasting facilitation of spinal reflexes independent of ionotropic receptor activity.
Journal: Journal of neurophysiology 20051001
Title: Inhibition of serotonin transporters by cocaine and meprylcaine through 5-TH2C receptor stimulation facilitates their seizure activities.
Journal: Brain research 20050928
Title: Updated overview of the putative role of the serotoninergic system in obsessive-compulsive disorder.
Journal: Neuropsychiatric disease and treatment 20050901
Title: Attenuation of nicotine's discriminative stimulus effects in rats and its locomotor activity effects in mice by serotonergic 5-HT2A/2C receptor agonists.
Journal: Psychopharmacology 20050501
Title: Contribution of serotonin (5-hydroxytryptamine; 5-HT) 5-HT2 receptor subtypes to the hyperlocomotor effects of cocaine: acute and chronic pharmacological analyses.
Journal: The Journal of pharmacology and experimental therapeutics 20040901
Title: Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20040801
Title: Different roles of 5-HT2A and 5-HT2C receptors in regulation of female rat paced mating behaviour.
Journal: Behavioural brain research 20040302
Title: Antiallodynic effects of intrathecally administered 5-HT(2C) receptor agonists in rats with nerve injury.
Journal: Pain 20040301
Title: Anxiogenic effects in the rat elevated plus-maze of 5-HT(2C) agonists into ventral but not dorsal hippocampus.
Journal: Behavioural pharmacology 20040201
Title: Agonist actions of dihydroergotamine at 5-HT2B and 5-HT2C receptors and their possible relevance to antimigraine efficacy.
Journal: British journal of pharmacology 20030901
Title: Hyperlocomotive and discriminative stimulus effects of cocaine are under the control of serotonin(2C) (5-HT(2C)) receptors in rat prefrontal cortex.
Journal: The Journal of pharmacology and experimental therapeutics 20030801
Title: Discriminative stimulus properties of (+/-)-fenfluramine: the role of 5-HT2 receptor subtypes.
Journal: Behavioral neuroscience 20030401
Title: Activation of presynaptic 5-hydroxytryptamine 2A receptors facilitates excitatory synaptic transmission via protein kinase C in the dorsolateral septal nucleus.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020901
Title: Serotonin 5-HT(2C) receptors in nucleus accumbens regulate expression of the hyperlocomotive and discriminative stimulus effects of cocaine.
Journal: Pharmacology, biochemistry, and behavior 20020401
Title: Serotonin(2) receptors mediate respiratory recovery after cervical spinal cord hemisection in adult rats.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20011201
Title: Modulation of 5-HT(2A) receptor-mediated head-twitch behaviour in the rat by 5-HT(2C) receptor agonists.
Journal: Pharmacology, biochemistry, and behavior 20010101
Title: Agonist high and low affinity state ratios predict drug intrinsic activity and a revised ternary complex mechanism at serotonin 5-HT(2A) and 5-HT(2C) receptors.
Journal: Synapse (New York, N.Y.) 20000201
Title: Serotonin(2C) receptors appear to mediate genetic sensitivity to cocaine-induced convulsions.
Journal: Psychopharmacology 19991001
Title: Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Journal: Molecular pharmacology 19930301
Title: Serotonergic drugs, benzodiazepines and baclofen block muscimol-induced myoclonic jerks in a strain of mice.
Journal: European journal of pharmacology 19810717
