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Home Other Building Blocks 62645-28-7
62645-28-7,MFCD06660085
Catalog No.:AA00EB17

62645-28-7 | RO 106-9920

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$70.00   $49.00
- +
5mg
≥95%
in stock  
$156.00   $109.00
- +
10mg
≥95%
in stock  
$226.00   $158.00
- +
  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00EB17
Chemical Name:
RO 106-9920
CAS Number:
62645-28-7
Molecular Formula:
C10H7N5OS
Molecular Weight:
245.2605
MDL Number:
MFCD06660085
SMILES:
O=S(c1ccc2n(n1)nnn2)c1ccccc1
Properties
Computed Properties
 
Complexity:
296  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
6  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
1  
XLogP3:
1  

Literature

Title: Nuclear factor κB is a key transcription factor in the duodenal contractility alterations induced by lipopolysaccharide.

Journal: Experimental physiology 20111101

Title: Discovery of novel small molecule cell type-specific enhancers of NF-kappaB nuclear translocation.

Journal: Bioorganic & medicinal chemistry letters 20090215

Title: IL-6 mediated alterations on immobile behavior of rats in the forced swim test via ERK1/2 activation in specific brain regions.

Journal: Behavioural brain research 20081121

Title: Amitriptyline induces nuclear transcription factor-kappaB-dependent glutamate transporter upregulation in chronic morphine-infused rats.

Journal: Neuroscience 20080515

Title: Identification of N-(quinolin-8-yl)benzenesulfonamides as agents capable of down-regulating NFkappaB activity within two separate high-throughput screens of NFkappaB activation.

Journal: Bioorganic & medicinal chemistry letters 20080101

Title: A small molecule ubiquitination inhibitor blocks NF-kappa B-dependent cytokine expression in cells and rats.

Journal: The Journal of biological chemistry 20020628

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Tags:62645-28-7 Molecular Formula|62645-28-7 MDL|62645-28-7 SMILES|62645-28-7 RO 106-9920