Home Amines 579-56-6
579-56-6,MFCD00058069
Catalog No.:AA00EBFJ

579-56-6 | Benzenemethanol,4-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-, hydrochloride

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5g
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00EBFJ
Chemical Name:
Benzenemethanol,4-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-, hydrochloride
CAS Number:
579-56-6
Molecular Formula:
C18H24ClNO3
Molecular Weight:
337.8411
MDL Number:
MFCD00058069
SMILES:
CC(NC(C(c1ccc(cc1)O)O)C)COc1ccccc1.Cl
Properties
Computed Properties
 
Complexity:
299  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
3  

Literature

Title: Prophylactic oral betamimetics for reducing preterm birth in women with a twin pregnancy.

Journal: The Cochrane database of systematic reviews 20120912

Title: Veterinary treatment of cows with isoxsuprine for a caesarian section may temporarily lead to residues in hair of both cow and calf.

Journal: Drug testing and analysis 20120601

Title: Beta2-adrenoceptor agonists for dysmenorrhoea.

Journal: The Cochrane database of systematic reviews 20120516

Title: Intermittent claudication-like syndrome secondary to atherosclerosis in a yellow-naped Amazon parrot (Amazona ochrocephala auropalliata).

Journal: Journal of avian medicine and surgery 20111201

Title: Atosiban versus betamimetics in the treatment of preterm labour in Italy: clinical and economic importance of side-effects.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20110801

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Development and validation of fixed-time method for the determination of isoxsuprine hydrochloride in commercial dosages forms.

Journal: Drug testing and analysis 20100901

Title: Investigation of ractopamine molecularly imprinted stir bar sorptive extraction and its application for trace analysis of beta2-agonists in complex samples.

Journal: Journal of chromatography. A 20100528

Title: Simultaneous determination of ritodrine and isoxsuprine using coupling technique of synchronous fluorimetry and H-point standard addition method.

Journal: Journal of fluorescence 20100101

Title: Use of isoxsuprine hydrochloride as a tocolytic agent in the treatment of preterm labour: a systematic review of previous literature.

Journal: Arzneimittel-Forschung 20100101

Title: Molecularly imprinted polymer for the determination of trace ractopamine in pork using SPE followed by HPLC with fluorescence detection.

Journal: Journal of separation science 20090501

Title: Drugs to treat Alzheimer's disease.

Journal: Journal of psychosocial nursing and mental health services 20090401

Title: Pharmacokinetics of isoxsuprine hydrochloride administered orally and intramuscularly to female healthy volunteers.

Journal: Arzneimittel-Forschung 20090101

Title: Ritodrine and isoxsuprine in management of preterm labor.

Journal: JNMA; journal of the Nepal Medical Association 20090101

Title: Effects of alcohols on CE enantioseparation of basic drugs with native gamma-CD as chiral selector.

Journal: Journal of separation science 20080801

Title: Prophylactic oral betamimetics for preventing preterm labour in singleton pregnancies.

Journal: The Cochrane database of systematic reviews 20080123

Title: Use of isoxsuprine for treatment of clinical signs associated with presumptive atherosclerosis in a yellow-naped Amazon parrot (Amazona ochrocephala auropalliata).

Journal: Journal of avian medicine and surgery 20070901

Title: Synthesis and evaluation of uterine relaxant activity for a novel series of substituted p-hydroxyphenylethanolamines.

Journal: Bioorganic & medicinal chemistry 20061001

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Design, synthesis and evaluation of racemic 1-(4-hydroxyphenyl)-2-[3-(substituted phenoxy)-2-hydroxy-1-propyl]amino-1-propanol hydrochlorides as novel uterine relaxants.

Journal: Bioorganic & medicinal chemistry letters 20050801

Title: Determination of beta-agonist residues in bovine urine using liquid chromatography-tandem mass spectrometry.

Journal: Journal of AOAC International 20050101

Title: Determination of isoxsuprine hydrochloride by sequential injection visible spectrophotometry.

Journal: Farmaco (Societa chimica italiana : 1989) 20050101

Title: A GC-MS method for the determination of isoxsuprine in biological fluids of the horse utilizing electron impact ionization.

Journal: Journal of analytical toxicology 20040101

Title: An analgesic evaluation of isoxsuprine in horses.

Journal: Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20040101

Title: A comparative study between nifedipine and isoxsuprine in the suppression of preterm labour.

Journal: Kathmandu University medical journal (KUMJ) 20030101

Title: A simple kinetic spectrophotometric method for the determination of isoxsuprine in dosage forms.

Journal: Farmaco (Societa chimica italiana : 1989) 20020801

Title: Fluorimetric determination of isoxsuprine hydrochloride in pharmaceuticals and biological fluids.

Journal: Journal of pharmaceutical and biomedical analysis 20020415

Title: Isoxsuprine hydrochloride in the horse: a review.

Journal: Journal of veterinary pharmacology and therapeutics 20020401

Title: Enantioseparation of chiral vasodilator drug isoxsuprine in high-performance liquid chromatography and capillary electrophoresis.

Journal: Journal of pharmaceutical and biomedical analysis 20020101

Title: Therapeutic effects of high-dose isoxsuprine in the management of mixed-type impotence.

Journal: Urology 20010701

Title: Transient electrocardiographic changes suggesting myocardial ischaemia in newborn infants following tocolysis with beta-sympathomimetics.

Journal: European journal of pediatrics 19900701

Title: Myotonic muscular dystrophy associated with ritodrine tocolysis.

Journal: American journal of obstetrics and gynecology 19850101

Title: Maternal morbidity associated with isoxsuprine and terbutaline tocolysis.

Journal: European journal of obstetrics, gynecology, and reproductive biology 19810501

Title: Effect of intravenous infusion of betasympathomimetic agents on plasma renin activity during pregnancy.

Journal: British journal of obstetrics and gynaecology 19781101

Title: Effects of phentolamine, dihydroergocristine and isoxsuprine on the blood pressure and heart rate in normotensive, hypotensive and hypertensive rats.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 19750101

Title: Falkay G, et al. Affinity of tocolytic agents on human placental and myometrial beta-adrenergic receptors. J Perinat Med. 1986;14(2):109-13.

Title: Kretschy N, et al. In vitro inhibition of breast cancer spheroid-induced lymphendothelial defects resembling intravasation into the lymphatic vasculature by acetohexamide, isoxsuprine, nifedipin and proadifen. Br J Cancer. 2013 Feb 19;108(3):570-8.

Title: Hill JW, et al. Identification of isoxsuprine hydrochloride as a neuroprotectant in ischemic stroke through cell-based high-throughput screening. PLoS One. 2014 May 7;9(5):e96761.

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Tags:579-56-6 Molecular Formula|579-56-6 MDL|579-56-6 SMILES|579-56-6 Benzenemethanol,4-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-, hydrochloride