[1]Ruchelman,AlexanderL.;Man,Hon-Wah;Chen,Roger;Liu,Wei;Lu,Ling;Cedzik,Dorota;Zhang,Ling;Leisten,Jim;Collette,Alice;Narla,RamaKrishna;Raymon,HeatherK.;Muller,GeorgeW.[BioorganicandMedicinalChemistry,2011,vol.19,#21,p.6356-6374]
[1]Ruchelman,AlexanderL.;Man,Hon-Wah;Chen,Roger;Liu,Wei;Lu,Ling;Cedzik,Dorota;Zhang,Ling;Leisten,Jim;Collette,Alice;Narla,RamaKrishna;Raymon,HeatherK.;Muller,GeorgeW.[BioorganicandMedicinalChemistry,2011,vol.19,#21,p.6356-6374]
[1]BioorganicandMedicinalChemistry,2011,vol.19,p.6356-6374
[2]Patent:WO2012/173280,2012,A1
[3]Patent:WO2012/173280,2012,A1
[4]Patent:WO2012/173280,2012,A1
[1]BioorganicandMedicinalChemistry,2011,vol.19,p.6356-6374
[1]Ruchelman,AlexanderL.;Man,Hon-Wah;Chen,Roger;Liu,Wei;Lu,Ling;Cedzik,Dorota;Zhang,Ling;Leisten,Jim;Collette,Alice;Narla,RamaKrishna;Raymon,HeatherK.;Muller,GeorgeW.[BioorganicandMedicinalChemistry,2011,vol.19,#21,p.6356-6374]
[2]CurrentPatentAssignee:TAKEDAPHARMACEUTICALCOMPANYLIMITED-WO2012/173280,2012,A1Locationinpatent:Page/Pagecolumn31-32
Title: Changing paradigms in management of metastatic Castration Resistant Prostate Cancer (mCRPC).
Journal: BMC urology 20140101
Title: Orteronel (TAK-700), a novel non-steroidal 17,20-lyase inhibitor: effects on steroid synthesis in human and monkey adrenal cells and serum steroid levels in cynomolgus monkeys.
Journal: The Journal of steroid biochemistry and molecular biology 20120401
Title: Discovery of orteronel (TAK-700), a naphthylmethylimidazole derivative, as a highly selective 17,20-lyase inhibitor with potential utility in the treatment of prostate cancer.
Journal: Bioorganic & medicinal chemistry 20111101
Title: CYP17 inhibitors for prostate cancer therapy.
Journal: The Journal of steroid biochemistry and molecular biology 20110501
Title: Yamaoka M, et al. Orteronel (TAK-700), a novel non-steroidal 17,20-lyase inhibitor: effects on steroid synthesis in human and monkey adrenal cells and serum steroid levels in cynomolgus monkeys.J Steroid Biochem Mol Biol. 2012 Apr;129(3-5):115-28.
Title: Kaku, Tomohiro., et al. Discovery of orteronel (TAK-700), a naphthylmethylimidazole derivative, as a highly selective 17,20-lyase inhibitor with potential utility in the treatment of prostate cancer. From Bioorganic & Medicinal Chemistry (2011), 19(21), 6
