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Home Other Building Blocks 5868-05-3
5868-05-3,MFCD00215982
Catalog No.:AA00EFSZ

5868-05-3 | Niceritrol

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
95%
in stock  
$131.00   $92.00
- +
25mg
95%
in stock  
$338.00   $237.00
- +
100mg
95%
in stock  
$897.00   $628.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00EFSZ
Chemical Name:
Niceritrol
CAS Number:
5868-05-3
Molecular Formula:
C29H24N4O8
Molecular Weight:
556.5229
MDL Number:
MFCD00215982
SMILES:
O=C(c1cccnc1)OCC(COC(=O)c1cccnc1)(COC(=O)c1cccnc1)COC(=O)c1cccnc1
Properties
Computed Properties
 
Complexity:
745  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
41  
Hydrogen Bond Acceptor Count:
12  
Rotatable Bond Count:
16  
XLogP3:
2.3  

Downstream Synthesis Route

[1]Grosshans,Philippe;Jouaiti,Abdelaziz;Hosseini,MirWais;Kyritsakas,Nathalie[NewJournalofChemistry,2003,vol.27,#5,p.793-797]

[2]Badgett;Woodward[JournaloftheAmericanChemicalSociety,1947,vol.69,p.2907]

[3]Charonnatetal.[BulletindelaSocieteChimiquedeFrance,1948,p.1014,1015]

tetrachloroethane 
  7732-18-5    5868-05-3   
mercurydichloride 
 
Hg(2+)*2Cl(1-)*C(CH2OOCC5H4N)4*0.5C2H2Cl4*H2O=HgCl2(C(CH2OOCC5H4N)4)*0.5C2H2Cl4*H2O 

[1]Grosshans,Philippe;Jouaiti,Abdelaziz;Hosseini,MirWais;Kyritsakas,Nathalie[NewJournalofChemistry,2003,vol.27,#5,p.793-797]

67-56-1   
copper(ll)sulfatepentahydrate 
  7732-18-5    5868-05-3   
Cutetrakis(nicotinoxymethyl)methane(SO4)(H2O)2(CH3OH)2(H2O)8 

[1]Naettinen,KalleI.;Linnanto,Juha;Rissanen,Kari[EuropeanJournalofInorganicChemistry,2003,#22,p.4078-4086]

Literature

Title: Attenuation of niacin-induced prostaglandin D(2) generation by omega-3 fatty acids in THP-1 macrophages and Langerhans dendritic cells.

Journal: Journal of inflammation research 20120101

Title: Successful treatment of lipoprotein glomerulopathy in a daughter and a mother using niceritrol.

Journal: Clinical and experimental nephrology 20101201

Title: Binder blinders-niacin of omission?

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20100401

Title: The mechanism and mitigation of niacin-induced flushing.

Journal: International journal of clinical practice 20090901

Title: Transplantation of bone marrow-derived mesenchymal stem cells improves diabetic polyneuropathy in rats.

Journal: Diabetes 20081101

Title: Effect of levothyroxine on total lipid profiles as assessed by analytical capillary isotachophoresis in a patient with hypothyroidism.

Journal: Endocrine journal 20061201

Title: [Dyslipidemia in renal failure].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040601

Title: Antiproteinuric effect of niceritrol, a nicotinic acid derivative, in chronic renal disease with hyperlipidemia: a randomized trial.

Journal: The American journal of medicine 20030401

Title: Resolution of typical lipoprotein glomerulopathy by intensive lipid-lowering therapy.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20030101

Title: The effects of combination therapy with niceritrol and pravastatin on hyperlipidaemia.

Journal: The Journal of international medical research 20020101

Title: Effect of niceritrol on streptozocin-induced diabetic neuropathy in rats.

Journal: Diabetes 19920501

Title: Enzymatic hydrolysis of pentaerythritoltetranicotinate and meso-inositolhexanicotinate in blood and tissues.

Journal: Arzneimittel-Forschung 19790101

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SDS
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