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62402-31-7,MFCD01678759
Catalog No.:AA00ELXV

62402-31-7 | NSC 26480 (5,6-dihydro-5-azacytidine)

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Purity
Availability
Price(USD)
Quantity
  
10mg
≥99%
in stock  
$254.00   $178.00
- +
50mg
≥99%
in stock  
$831.00   $582.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00ELXV
Chemical Name:
NSC 26480 (5,6-dihydro-5-azacytidine)
CAS Number:
62402-31-7
Molecular Formula:
C8H15ClN4O5
Molecular Weight:
282.6815
MDL Number:
MFCD01678759
SMILES:
OCC1OC(C(C1O)O)N1CN=C(NC1=O)N.Cl
Properties
Computed Properties
 
Complexity:
349  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
6  
Rotatable Bond Count:
2  

Literature

Title: 5-azacytosine compounds in medicinal chemistry: current stage and future perspectives.

Journal: Future medicinal chemistry 20120501

Title: Response to the methylation inhibitor dihydro-5-azacytidine in mesothelioma is not associated with methylation of p16INK4a: results of cancer and leukemia group B 159904.

Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080401

Title: KP-1212/1461, a nucleoside designed for the treatment of HIV by viral mutagenesis.

Journal: Antiviral research 20050701

Title: Dihydro-5-azacytidine and cisplatin in the treatment of malignant mesothelioma: a phase II study by the Cancer and Leukemia Group B.

Journal: Cancer 19980415

Title: Dihydro-5-azacytidine in malignant mesothelioma. A phase II trial demonstrating activity accompanied by cardiac toxicity. Cancer and Leukemia Group B.

Journal: Cancer 19970601

Title: A phase II study of 5,6-dihydro-5-azacytidine hydrochloride in disseminated malignant melanoma.

Journal: American journal of clinical oncology 19930601

Title: Fetal hemoglobin gene activation in a phase II study of 5,6-dihydro-5-azacytidine for bronchogenic carcinoma.

Journal: Cancer research 19870801

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