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71012-19-6,MFCD29045295
Catalog No.:AA00F9RJ

71012-19-6 | ASIALOGANGLIOSIDE-GM1

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1mg
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00F9RJ
Chemical Name:
ASIALOGANGLIOSIDE-GM1
CAS Number:
71012-19-6
Molecular Formula:
C62H114N2O23
Molecular Weight:
1255.5682
MDL Number:
MFCD29045295
SMILES:
CCCCCCCCCCCCC/C=C/[C@H]([C@@H](NC(=O)CCCCCCCCCCCCCCCCC)CO[C@@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O[C@@H]1O[C@H](CO)[C@@H]([C@@H]([C@H]1O)O)O[C@@H]1O[C@H](CO)[C@@H]([C@@H]([C@H]1NC(=O)C)O[C@@H]1O[C@H](CO)[C@@H]([C@@H]([C@H]1O)O)O)O)O
Properties
Computed Properties
 
Complexity:
1830  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
19  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
87  
Hydrogen Bond Acceptor Count:
23  
Hydrogen Bond Donor Count:
15  
Rotatable Bond Count:
45  
Undefined Atom Stereocenter Count:
3  
XLogP3:
6.5  

Literature

Title: Excretion into feces of asialo GM1 in the murine digestive tract and Lactobacillus johnsonii exhibiting binding ability toward asialo GM1. A possible role of epithelial glycolipids in the discharge of intestinal bacteria.

Journal: Glycoconjugate journal 20110101

Title: Antibodies to ganglioside complexes consisting of asialo-GM1 and GQ1b or GT1a in Fisher and Guillain-Barré syndromes.

Journal: Journal of neuroimmunology 20090929

Title: Vaccines using dendritic cells, differentiated with propofol, enhance antitumor immunity in mice.

Journal: Immunopharmacology and immunotoxicology 20090101

Title: Near-field scanning optical microscopy detects nanoscale glycolipid domains in the plasma membrane.

Journal: Journal of microscopy 20081101

Title: Neuritogenic effects of T cell-derived IL-3 on mouse splenic sympathetic neurons in vivo.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20080315

Title: Are natural killer cells distributed in relationship to nerve fibers in the pregnant mouse uterus?

Journal: Pakistan journal of biological sciences : PJBS 20070901

Title: Synthesis of reference standards to enable single cell metabolomic studies of tetramethylrhodamine-labeled ganglioside GM1.

Journal: Carbohydrate research 20070226

Title: Pseudomonas aeruginosa mucoid strain 8830 binds glycans containing the sialyl-Lewis x epitope.

Journal: Glycoconjugate journal 20070101

Title: AsialoGM1-mediated IL-8 release by human corneal epithelial cells requires coexpression of TLR5.

Journal: Investigative ophthalmology & visual science 20061101

Title: NK-cell-dependent acute xenograft rejection in the mouse heart-to-rat model.

Journal: Xenotransplantation 20060901

Title: AsialoGM1 and TLR5 cooperate in flagellin-induced nucleotide signaling to activate Erk1/2.

Journal: American journal of respiratory cell and molecular biology 20060601

Title: Flagellin of Pseudomonas aeruginosa inhibits Na+ transport in airway epithelia.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301

Title: Cardiovascular dysfunction caused by cecal ligation and puncture is attenuated in CD8 knockout mice treated with anti-asialoGM1.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20050801

Title: Galectins as markers of aggressiveness of mouse mammary carcinoma: towards a lectin target therapy of human breast cancer.

Journal: Breast cancer research and treatment 20050601

Title: Interferon alpha 2b decreases hepatic micrometastasis in a murine model of ocular melanoma by activation of intrinsic hepatic natural killer cells.

Journal: Investigative ophthalmology & visual science 20040701

Title: Effect of rabbit anti-asialo-GM1 (GA1) polyclonal antibodies on neuromuscular transmission and acetylcholine-induced action potentials: neurophysiological and immunohistochemical studies.

Journal: Neurochemical research 20040501

Title: Oligosaccharide receptor mimics inhibit Legionella pneumophila attachment to human respiratory epithelial cells.

Journal: Microbial pathogenesis 20040201

Title: Binding of Bifidobacterium bifidum and Lactobacillus reuteri to the carbohydrate moieties of intestinal glycolipids recognized by peanut agglutinin.

Journal: International journal of food microbiology 20040201

Title: Alzheimer's disease: NMR studies of asialo (GM1) and trisialo (GT1b) ganglioside interactions with Abeta(1-40) peptide in a membrane mimic environment.

Journal: Neurochemical research 20040201

Title: [Synthesis of aminoethylglycosides with oligosaccharide GM1 and asialo-GM1 ganglioside chains].

Journal: Bioorganicheskaia khimiia 20040101

Title: Reduction of liver metastasis of intraocular melanoma by interferon-beta gene transfer.

Journal: Investigative ophthalmology & visual science 20030701

Title: YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1.

Journal: Journal of the National Cancer Institute 20030402

Title: Molecular markers that identify human astrocytomas and oligodendrogliomas.

Journal: Journal of neuropathology and experimental neurology 20020401

Title: Glycolipid analysis of different tissues and cerebrospinal fluid in type II Gaucher disease.

Journal: Journal of inherited metabolic disease 20020201

Title: Inhibition of binding of Helicobacter pylori to the glycolipid receptors by probiotic Lactobacillus reuteri.

Journal: FEMS immunology and medical microbiology 20020114

Title: Cystic fibrosis pathogens activate Ca2+-dependent mitogen-activated protein kinase signaling pathways in airway epithelial cells.

Journal: The Journal of biological chemistry 20010601

Title: Mechanisms of the antimetastatic effect in the liver and of the hepatocyte injury induced by alpha-galactosylceramide in mice.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010601

Title: Pseudomonas aeruginosa infection of respiratory epithelium in a cystic fibrosis xenograft model.

Journal: The Journal of infectious diseases 20010315

Title: Guillain-Barre syndrome following 2-chlorodeoxyadenosine treatment for Hairy Cell Leukemia.

Journal: Leukemia & lymphoma 20001101

Title: Mapping immunoreactive epitopes in the human peripheral nervous system using human monoclonal anti-GM1 ganglioside antibodies.

Journal: Acta neuropathologica 19980601

Title: Anti-fucosyl-GM1 ganglioside IgG and IgM autoantibodies in human serum: no link to pathology.

Journal: Immunology letters 19960901

Title: Monoclonal IgM antibodies to GM1 and asialo-GM1 in chronic neuropathies cross-react with Campylobacter jejuni lipopolysaccharides.

Journal: Annals of neurology 19940601

Title: Anti-GM1 ganglioside antibodies with differing fine specificities in patients with multifocal motor neuropathy.

Journal: Journal of neuroimmunology 19891201

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Tags:71012-19-6 Molecular Formula|71012-19-6 MDL|71012-19-6 SMILES|71012-19-6 ASIALOGANGLIOSIDE-GM1