[1]CurrentPatentAssignee:VERASTEMINC;PFIZERINC-US2011/33441,2011,A1Locationinpatent:Page/Pagecolumn9
[1]CurrentPatentAssignee:VERASTEMINC;PFIZERINC-US2011/33441,2011,A1Locationinpatent:Page/Pagecolumn8
[1]CurrentPatentAssignee:VERASTEMINC;PFIZERINC-US2011/33441,2011,A1Locationinpatent:Page/Pagecolumn10
[1]CurrentPatentAssignee:VERASTEMINC;PFIZERINC-US2011/33441,2011,A1Locationinpatent:Page/Pagecolumn10
Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.
Journal: Bioorganic & medicinal chemistry letters 20130801
Title: The role of focal adhesion kinase catalytic activity on the proliferation and migration of squamous cell carcinoma cells.
Journal: International journal of cancer 20120715
Title: Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: structure-activity relationships and discovery strategies to mitigate drug-drug interaction risks.
Journal: Journal of medicinal chemistry 20120614
Title: Inhibition of focal adhesion kinase prevents experimental lung fibrosis and myofibroblast formation.
Journal: Arthritis and rheumatism 20120501
Title: Inhibition of focal adhesion kinase by PF-562,271 inhibits the growth and metastasis of pancreatic cancer concomitant with altering the tumor microenvironment.
Journal: Molecular cancer therapeutics 20111101
Title: Clinical importance and potential use of small molecule inhibitors of focal adhesion kinase.
Journal: Anti-cancer agents in medicinal chemistry 20110901
Title: Transforming growth factor-β-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression.
Journal: Oncogene 20101209
Title: Bioluminescent imaging study: FAK inhibitor, PF-562,271, preclinical study in PC3M-luc-C6 local implant and metastasis xenograft models.
Journal: Cancer biology & therapy 20100701
Title: Emerging targets in osteoporosis disease modification.
Journal: Journal of medicinal chemistry 20100610
Title: Sunitinib and PF-562,271 (FAK/Pyk2 inhibitor) effectively block growth and recovery of human hepatocellular carcinoma in a rat xenograft model.
Journal: Cancer biology & therapy 20090501
Title: Therapeutic targeting of the focal adhesion complex prevents oncogenic TGF-beta signaling and metastasis.
Journal: Breast cancer research : BCR 20090101
Title: Dual focal adhesion kinase/Pyk2 inhibitor has positive effects on bone tumors: implications for bone metastases.
Journal: Cancer 20080515
Title: Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271.
Journal: Cancer research 20080315
Title: Roberts WG, et al. Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271. Cancer Res, 2008, 68(6), 1935-1944.
Title: Crompton BD, et al. High-throughput tyrosine kinase activity profiling identifies FAK as a candidate therapeutic target in Ewing sarcoma. Cancer Res. 2013 May 1;73(9):2873-83.
Title: Bagi CM, et al. Dual focal adhesion kinase/Pyk2 inhibitor has positive effects on bone tumors: implications for bone metastases. Cancer. 2008 May 15;112(10):2313-21.
