Name: Name:Anagliptin
Brand: AABLOCKS
SKU: AA00FBYL
Rating: 90 (10 reviews)

Catalog No.: AA00FBYL

739366-20-2 | Anagliptin

Pack Size： 1mg

Purity： ≥95%

in stock

$63.00 $44.00

Pack Size： 5mg

Purity： ≥95%

in stock

$268.00 $187.00

Pack Size： 10mg

Purity： ≥95%

in stock

$502.00 $351.00

Pack Size： 250mg

Purity： 95%

in stock

$884.00 $619.00

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Technical Information

Catalog Number: AA00FBYL

Chemical Name: Anagliptin

CAS Number: 739366-20-2

Molecular Formula: C19H25N7O2

Molecular Weight: 383.4475

MDL Number: MFCD19443729

SMILES: N#C[C@@H]1CCCN1C(=O)CNC(CNC(=O)c1cnc2n(c1)nc(c2)C)(C)C

Properties

Complexity: 643

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 1

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 28

Hydrogen Bond Acceptor Count: 6

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 6

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 0

Downstream Synthesis Route

739364-95-5

(S)-1-(2-amino-1,1-dimethylethyl)aminoacetylpyrrolidine-2-carbonitriledihydrochloride

(S)-2-methylpyrazolo1,5-apyrimidine-6-carboxylicacid{2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino-2-methylpropyl}amide

[1]Patent:CN105399742,2016,A.Locationinpatent:Paragraph0050;0051;0052;0053;0058;0059;0060

[2]Patent:WO2015/104602,2015,A3.Locationinpatent:Page/Pagecolumn30

739366-20-2

1359670-56-6

[1]CurrentPatentAssignee:WOCKHARDTLIMITED-WO2015/104602,2015,A3Locationinpatent:Page/Pagecolumn31

[2]CurrentPatentAssignee:SUZUKENCOLTD-US2015/239890,2015,A1Locationinpatent:Paragraph0050

739365-95-8

739366-20-2

[1]Yan,Xin;Bain,RyanM.;Li,Yafeng;Qiu,Ran;Flick,TawnyaG.;Cooks,R.Graham[OrganicProcessResearchandDevelopment,2016,vol.20,#5,p.940-947]

[2]CurrentPatentAssignee:HAIMENBAIKANGPHARMACEUTICAL-CN105503878,2016,A

[3]CurrentPatentAssignee:WOCKHARDTLIMITED-WO2015/104602,2015,A3

739366-20-2

104-15-4

1567838-27-0

[1]CurrentPatentAssignee:SUZUKENCOLTD-US2015/239890,2015,A1Locationinpatent:Paragraph0051

Literature fold

Title: Discovery and pharmacological characterization of N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide hydrochloride (anagliptin hydrochloride salt) as a potent and selective DPP-IV inhibitor.

Journal: Bioorganic & medicinal chemistry20111201

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