Home Amines 6673-35-4
6673-35-4,MFCD00864573
Catalog No.:AA00FDJR

6673-35-4 | N-(4-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide

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5mg
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$150.00   $105.00
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10mg
98%
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$204.00   $143.00
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25mg
98%
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$350.00   $245.00
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50mg
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100mg
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00FDJR
Chemical Name:
N-(4-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide
CAS Number:
6673-35-4
Molecular Formula:
C14H22N2O3
Molecular Weight:
266.3361
MDL Number:
MFCD00864573
SMILES:
OC(COc1ccc(cc1)NC(=O)C)CNC(C)C
Properties
Properties
 
BP:
409.54°C (rough estimate)  
Form:
Solid  
MP:
134-136° (BuOAc)  
Refractive Index:
1.5110 (estimate)  

Computed Properties
 
Complexity:
263  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
1  
XLogP3:
0.8  

Literature

Title: Trachomatous trichiasis and its management in endemic countries.

Journal: Survey of ophthalmology 20120301

Title: Sclerosing peritonitis: a rare but fatal complication of peritoneal inflammation.

Journal: Mediators of inflammation 20120101

Title: Importance of physicochemical properties for the design of new pesticides.

Journal: Journal of agricultural and food chemistry 20110413

Title: Evolution of β-blockers: from anti-anginal drugs to ligand-directed signalling.

Journal: Trends in pharmacological sciences 20110401

Title: Management of acute idiopathic sensorineural hearing loss: a survey of UK ENT consultants.

Journal: Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale 20110401

Title: Label-free integrative pharmacology on-target of drugs at the β(2)-adrenergic receptor.

Journal: Scientific reports 20110101

Title: Small bowel cocoon: a distinct disease with a new developmental etiology.

Journal: Case reports in surgery 20110101

Title: Beta3-adrenoceptor agonists: possible role in the treatment of overactive bladder.

Journal: Korean journal of urology 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Chiral separations of some beta-adrenergic agonists and antagonists on AmyCoat column by HPLC.

Journal: Chirality 20100101

Title: Comparison of esmolol and labetalol, in low doses, for attenuation of sympathomimetic response to laryngoscopy and intubation.

Journal: Saudi journal of anaesthesia 20100101

Title: A problem encapsulated - role of CT.

Journal: The Libyan journal of medicine 20100101

Title: Adverse drug effects in hospitalized elderly: data from the healthcare cost and utilization project.

Journal: Clinical pharmacology : advances and applications 20100101

Title: Beta-adrenergic stimulation and myocardial function in the failing heart.

Journal: Heart failure reviews 20091201

Title: Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.

Journal: Bioorganic & medicinal chemistry 20091001

Title: Bench-to-bedside review: Beta-adrenergic modulation in sepsis.

Journal: Critical care (London, England) 20090101

Title: Simulation-based cheminformatic analysis of organelle-targeted molecules: lysosomotropic monobasic amines.

Journal: Journal of computer-aided molecular design 20080901

Title: Abdominal cocoon secondary to tuberculosis.

Journal: Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20080701

Title: Clinical consequences of asbestos-related diffuse pleural thickening: A review.

Journal: Journal of occupational medicine and toxicology (London, England) 20080101

Title: Beta-blockers use in patients with chronic obstructive pulmonary disease and concomitant cardiovascular conditions.

Journal: International journal of chronic obstructive pulmonary disease 20071201

Title: An instructive example of a long-latency adverse drug reaction--sclerosing peritonitis due to practolol.

Journal: Pharmacoepidemiology and drug safety 20071101

Title: A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20071016

Title: Cutaneous vasculitis induced by carvedilol.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20070801

Title: QSAR study on permeability of hydrophobic compounds with artificial membranes.

Journal: Bioorganic & medicinal chemistry 20070601

Title: Carvedilol in the treatment of chronic heart failure: lessons from the Carvedilol Or Metoprolol European Trial.

Journal: Vascular health and risk management 20070201

Title: Computational approaches for modeling human intestinal absorption and permeability.

Journal: Journal of molecular modeling 20060701

Title: Experiences with carrier-mediated transport in liquid-phase microextraction.

Journal: Journal of chromatographic science 20060701

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Testing times: the emergence of the practolol disaster and its challenge to British drug regulation in the modern period.

Journal: Social history of medicine : the journal of the Society for the Social History of Medicine 20060401

Title: Putting theory into practice: James Black, receptor theory and the development of the beta-blockers at ICI, 1958-1978.

Journal: Medical history 20060101

Title: An unusual and difficult diagnosis of intestinal obstruction: The abdominal cocoon. Case report and review of the literature.

Journal: World journal of emergency surgery : WJES 20060101

Title: Tuberculous abdominal cocoon--a report of 6 cases and review of the Literature.

Journal: World journal of emergency surgery : WJES 20060101

Title: A ranked presentation of the MHRA/CSM (Medicines & Health Care Regulatory Agency/Committee on Safety of Medicines) Drug Analysis Print (DAP) data on practolol.

Journal: Pharmacoepidemiology and drug safety 20051001

Title: Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).

Journal: Journal of medicinal chemistry 20050505

Title: Liquid-phase microextraction based on carrier mediated transport combined with liquid chromatography-mass spectrometry. New concept for the determination of polar drugs in a single drop of human plasma.

Journal: Journal of chromatography. A 20050422

Title: Modeling the electrophoretic mobility of beta-blockers in capillary electrophoresis using artificial neural networks.

Journal: Farmaco (Societa chimica italiana : 1989) 20050301

Title: Clinical characteristics of dialysis related sclerosing encapsulating peritonitis: multi-center experience in Korea.

Journal: Yonsei medical journal 20050227

Title: The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.

Journal: British journal of pharmacology 20050201

Title: Application of data mining techniques in pharmacovigilance.

Journal: British journal of clinical pharmacology 20040201

Title: Improvement of peak shape and separation performance of beta-blockers in conventional reversed-phase columns using solvent modifiers.

Journal: Journal of chromatographic science 20030801

Title: [Toxicologic analysis of some adrenergic-beta blockers in the diagnosis of intoxications].

Journal: Archiwum medycyny sadowej i kryminologii 20030101

Title: Data-mining analyses of pharmacovigilance signals in relation to relevant comparison drugs.

Journal: European journal of clinical pharmacology 20021001

Title: Calculation of electrophoretic mobility in mixed solvent buffers in capillary zone electrophoresis using a mixture response surface method.

Journal: The Analyst 20020901

Title: Norepinephrine elicits beta2-receptor-mediated dilation of isolated human coronary arterioles.

Journal: Circulation 20020730

Title: Modulatory effect of the adrenergic system upon fibroblast proliferation: participation of beta 3-adrenoceptors.

Journal: Autonomic & autacoid pharmacology 20020601

Title: From toxic precursors to safe drugs. Mechanisms and relevance of idiosyncratic drug reactions.

Journal: Arzneimittel-Forschung 20020101

Title: [Enantiomeric separation of drugs based on macrocyclic antibiotics].

Journal: Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20010701

Title: Experimental and computational screening models for the prediction of intestinal drug absorption.

Journal: Journal of medicinal chemistry 20010607

Title: Quantitative structure-retention and retention-activity relationships of beta-blocking agents by micellar liquid chromatography.

Journal: Journal of chromatography. A 20010406

Title: Modern doctoring.

Journal: Clinical medicine (London, England) 20010101

Title: LK 204-545, a highly selective beta1-adrenoceptor antagonist at human beta-adrenoceptors.

Journal: European journal of pharmacology 19990219

Title: Atenolol-induced cutaneous vasculitis.

Journal: Cutis 19890301

Title: Effect of beta-adrenoceptor blocking agents on isolation and apomorphine-induced aggression in rodents.

Journal: Indian journal of physiology and pharmacology 19870101

Title: Investigation into the cardioregulatory properties of the alpha 1-adrenoceptor blocker indoramin.

Journal: British journal of pharmacology 19860201

Title: Central action of beta-adrenoceptor antagonists on blood pressure after acute administration in rats.

Journal: Journal de pharmacologie 19860101

Title: Prevention of epinephrine-induced hypokalemia by nonselective beta blockers.

Journal: The American journal of cardiology 19850830

Title: Stimulation of cyclic adenosine 3',5'-monophosphate formation in rabbit choroid plexus by beta-receptor agonists and vasoactive intestinal polypeptide.

Journal: Neuroscience letters 19850315

Title: Effect of some beta adrenergic blocking agents and phenytoin on potentiation of quinidine antiarrhythmic activity in the mouse.

Journal: Archives internationales de pharmacodynamie et de therapie 19840701

Title: Noninvasive assessment of chronotropic and inotropic response to preferential beta-1 and beta-2 adrenoceptor stimulation.

Journal: Clinical pharmacology and therapeutics 19840601

Title: [Antidotal treatment of acebutolol poisoning].

Journal: Arzneimittel-Forschung 19840101

Title: Hypokalaemia due to salbutamol overdosage.

Journal: British medical journal (Clinical research ed.) 19810815

Title: Effects of beta-adrenergic blocking drugs in hypertensive rats.

Journal: Journal of pharmacobio-dynamics 19800101

Title: The role of beta1- and beta2-adrenoceptors in the inhibition of gastric acid secretion in the dog.

Journal: British journal of pharmacology 19780901

Title: Peripheral neuropathy with disopyramide.

Journal: Lancet (London, England) 19780211

Title: Adverse reactions to practolol in hospitalized patients: a report from the Boston Collaborative Drug Surveillance Program.

Journal: European journal of clinical pharmacology 19771114

Title: Influence of several anesthetic agents on the effect of delta9-tetrahydrocannabinol on the heart rate and blood pressure of the mongrel dog.

Journal: European journal of pharmacology 19770701

Title: Effects of beta-adrenoceptor blocking agents, pindolol, alprenolol and practolol on blood pressure and heart rate in conscious renal hypertensive dogs.

Journal: Archives internationales de pharmacodynamie et de therapie 19770101

Title: Intermittent claudication complicating beta-blockade.

Journal: British medical journal 19760508

Title: Letter: Propranolol and the nephrotic syndrome.

Journal: British medical journal 19760417

Title: Comparison of verapamil and practolol in paroxysmal supraventricular tachycardia.

Journal: European journal of cardiology 19760301

Title: Analysis of cardiac chronotropic responses to diazepam and bromazepam in conscious trained dogs.

Journal: European journal of pharmacology 19760201

Title: The use of clonidine and practolol in the treatment of hypertension.

Journal: Annals of clinical research 19760201

Title: [Pharmacology of acebutolol in animals].

Journal: La Nouvelle presse medicale 19751231

Title: Effect of oral administration of various beta-blocking agents on the intraocular pressure in healthy volunteers.

Journal: Experimental eye research 19751101

Title: Effect of beta-adrenoceptor blocking drugs, physostigmine, and atropine on the toxicity of doxepin in mice.

Journal: Medical biology 19750801

Title: Beta blockade in lithium tremor.

Journal: Journal of neurology, neurosurgery, and psychiatry 19750701

Title: The use of practolol in supraventricular arrhythmias associated with acute illnesses.

Journal: The American journal of cardiology 19750501

Title: The effect of cold and diazepam on the toxicity of fenfluramine in mice.

Journal: Experientia 19750315

Title: Problems with practolol.

Journal: Drugs 19750101

Title: Method for the production of severe ventricular dysrhythmias in small laboratory animals.

Journal: Recent advances in studies on cardiac structure and metabolism 19750101

Title: Letter: Reaction to phenoxybenzamine.

Journal: Lancet (London, England) 19741221

Title: Practolol and bendrofluazide in treatment of hypertension.

Journal: British heart journal 19740901

Title: Effects of tiprenolol, practolol and propranolol on experimental ventricular tachyarrhythmias.

Journal: British journal of pharmacology 19740601

Title: [Therapeutic significance of the beta-receptor blockade in lithium-induced tremor. Therapeutic trials with Pindolol and Practolol].

Journal: Die Medizinische Welt 19740315

Title: A comparison of the experimental anti-arrhythmic properties of acebutolol (M and B 17,803), propranolol and practolol.

Journal: British journal of pharmacology 19740301

Title: Iakovidis D, et, al. In vitro activity of RO363, a beta1-adrenoceptor selective agonist. Br J Pharmacol. 1980 Apr;68(4):677-85.

Title: Adashi EY, et, al. Stimulation of beta 2-adrenergic responsiveness by follicle-stimulating hormone in rat granulosa cells in vitro and in vivo. Endocrinology. 1981 Jun;108(6):2170-8.

Title: Marshall RJ, et, al. Comparative effects of propranolol and practolol in the early stages of experimental canine myocardial infarction. Br J Pharmacol. 1976 Jun;57(2):295-303.

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Tags:6673-35-4 Molecular Formula|6673-35-4 MDL|6673-35-4 SMILES|6673-35-4 N-(4-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide