Name: Name:JNJ-10397049
Brand: AABLOCKS
SKU: AA00FDQ0
Rating: 90 (10 reviews)

Catalog No.: AA00FDQ0

708275-58-5 | JNJ-10397049

Pack Size： 1mg

Purity： ≥98%

in stock

$70.00 $49.00

Pack Size： 5mg

Purity： ≥98%

in stock

$240.00 $168.00

Pack Size： 10mg

Purity： ≥98%

in stock

$340.00 $238.00

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Technical Information

Catalog Number: AA00FDQ0

Chemical Name: JNJ-10397049

CAS Number: 708275-58-5

Molecular Formula: C19H20Br2N2O3

Molecular Weight: 484.1817

MDL Number: MFCD17170315

SMILES: O=C(Nc1ccc(cc1Br)Br)N[C@H]1COC(O[C@H]1c1ccccc1)(C)C

Properties

Complexity: 485

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 2

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 26

Hydrogen Bond Acceptor Count: 3

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 3

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 4.1

Literature fold

Title: Selective orexin receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters20130901

Title: Effects of orexins A and B on expression of orexin receptors and progesterone release in luteal and granulosa ovarian cells.

Journal: Regulatory peptides20121010

Title: Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement.

Journal: Psychopharmacology20110501

Title: Functional magnetic resonance imaging reveals different neural substrates for the effects of orexin-1 and orexin-2 receptor antagonists.

Journal: PloS one20110101

Title: Both orexin receptors are expressed in rat ovaries and fluctuate with the estrous cycle: effects of orexin receptor antagonists on gonadotropins and ovulation.

Journal: American journal of physiology. Endocrinology and metabolism20071001

Title: Novel substituted 4-phenyl-[1,3]dioxanes: potent and selective orexin receptor 2 (OX(2)R) antagonists.

Journal: Bioorganic & medicinal chemistry letters20040816

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