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67884-30-4,MFCD11100326
Catalog No.:AA00FH4O

67884-30-4 | Gigantol

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1mg
98%
1 week  
$83.00   $58.00
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5mg
99%
1 week  
$241.00   $169.00
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10mg
99%
1 week  
$360.00   $252.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00FH4O
Chemical Name:
Gigantol
CAS Number:
67884-30-4
Molecular Formula:
C16H18O4
Molecular Weight:
274.3117
MDL Number:
MFCD11100326
SMILES:
COc1cc(CCc2ccc(c(c2)O)OC)cc(c1)O
Properties
Computed Properties
 
Complexity:
284  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  
XLogP3:
2.7  

Downstream Synthesis Route

[1]JournaloftheChemicalSociety.PerkintransactionsI,1982,p.1467-1476

[2]JournaloftheChemicalSociety.PerkintransactionsI,1982,p.1467-1476

Literature

Title: [Comparison of phenolic components among different species of Dendrobium (Shihu fengdou) and determination of their active components--moscatilin and gigantol].

Journal: Se pu = Chinese journal of chromatography 20100601

Title: [Studies on chemical constituents of Dendrobium crystallinum].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080801

Title: Antinociceptive and anti-inflammatory effects of compounds isolated from Scaphyglottis livida and Maxillaria densa.

Journal: Journal of ethnopharmacology 20071101

Title: Gigantol isolated from the whole plants of Cymbidium goeringii inhibits the LPS-induced iNOS and COX-2 expression via NF-kappaB inactivation in RAW 264.7 macrophages cells.

Journal: Planta medica 20061001

Title: Design, microwave-assisted synthesis, and spasmolytic activity of 2-(alkyloxyaryl)-1H-benzimidazole derivatives as constrained stilbene bioisosteres.

Journal: Bioorganic & medicinal chemistry letters 20060815

Title: Endothelium-independent relaxation of aorta rings by two stilbenoids from the orchids Scaphyglottis livida.

Journal: Fitoterapia 20060401

Title: Phytotoxic activity of bibenzyl derivatives from the orchid Epidendrum rigidum.

Journal: Journal of agricultural and food chemistry 20050810

Title: Spasmolytic effects, mode of action, and structure-activity relationships of stilbenoids from Nidema boothii.

Journal: Journal of natural products 20040201

Title: [Analysis of 1H-NMR fingerprint in stem of Dendrobium loddigesii].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20021201

Title: Yu S, et al. Gigantol inhibits Wnt/β-catenin signaling and exhibits anticancer activity in breast cancer cells. BMC Complement Altern Med. 2018 Feb 14;18(1):59.

Title: Chen H, et al. Gigantol attenuates the proliferation of human liver cancer HepG2 cells through the PI3K/Akt/NF-κB signaling pathway. Oncol Rep. 2017 Feb;37(2):865-870.

Title: Déciga-Campos M, et al. Antinociceptive and anti-inflammatory effects of compounds isolated from Scaphyglottis livida and Maxillaria densa. J Ethnopharmacol. 2007 Nov 1;114(2):161-8.

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