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66000-40-6,MFCD01038078
Catalog No.:AA00FHV1

66000-40-6 | 1-[3-(Trifluoromethyl)phenyl]-4,5-dihydro-1h-pyrazol-3-amine

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5mg
≥95%
in stock  
$63.00   $44.00
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10mg
≥95%
in stock  
$120.00   $84.00
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50mg
≥95%
in stock  
$488.00   $341.00
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100mg
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$850.00   $595.00
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  • Technical Information
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  • Technical Information
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Technical Information
Catalog Number:
AA00FHV1
Chemical Name:
1-[3-(Trifluoromethyl)phenyl]-4,5-dihydro-1h-pyrazol-3-amine
CAS Number:
66000-40-6
Molecular Formula:
C10H10F3N3
Molecular Weight:
229.2017
MDL Number:
MFCD01038078
SMILES:
NC1=NN(CC1)c1cccc(c1)C(F)(F)F
Properties
Computed Properties
 
Complexity:
288  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
1.8  

Literature

Title: Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Journal: Journal of medicinal chemistry 20081113

Title: Anti-inflammatory activity of Acanthus ilicifolius.

Journal: Journal of ethnopharmacology 20081030

Title: 15-Lipoxygenase metabolites contribute to age-related reduction in acetylcholine-induced hypotension in rabbits.

Journal: American journal of physiology. Heart and circulatory physiology 20080701

Title: Pharmacological studies on Indian black tea (leaf variety) in acute and chronic inflammatory conditions.

Journal: Phytotherapy research : PTR 20080601

Title: Lethal, oedema, haemorrhagic activity of spotted butterfish (Scatophagus argus, Linn) sting extract and its neutralization by antiserum and pharmacological antagonists.

Journal: Indian journal of experimental biology 20050601

Title: Isolation of a haemorrhagic protein toxin (SA-HT) from the Indian venomous butterfish (Scatophagus argus, Linn) sting extract.

Journal: Indian journal of experimental biology 20040501

Title: Evidence for the involvement of a macrophage-derived chemotactic mediator in the neutrophil recruitment induced by staphylococcal enterotoxin B in mice.

Journal: Toxicon : official journal of the International Society on Toxinology 20021201

Title: Antioxidant activity of the methanol fraction of Pluchea indica root extract.

Journal: Phytotherapy research : PTR 20020601

Title: Signal transduction pathways for activation of extracellular signal-regulated kinase by arachidonic acid in rat neutrophils.

Journal: Journal of leukocyte biology 20010401

Title: Mouse macrophages release a neutrophil chemotactic mediator following stimulation by staphylococcal enterotoxin type A.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20010401

Title: A useful method for differential evaluation of anti-inflammatory effects due to cyclooxygenase and 5-lipoxygenase inhibitions in mice.

Journal: Japanese journal of pharmacology 19940801

Title: LTB4-induced transient neutropenia in the rat: a model for evaluating efficacy and bioavailability of LTB4 receptor antagonists.

Journal: Journal of pharmacological and toxicological methods 19931101

Title: Influence of rhein anthrone on peristaltic reflex of guinea-pig isolated ileum: involvement of prostaglandins.

Journal: British journal of pharmacology 19930101

Title: Arachidonic acid-induced calcium influx in human platelets. Comparison with the effect of thrombin.

Journal: The Biochemical journal 19901201

Title: Simple procedure for measuring the pharmacodynamics and analgesic potential of lipoxygenase inhibitors.

Journal: Journal of pharmacological methods 19881201

Title: Meclofenamate sodium is an inhibitor of both the 5-lipoxygenase and cyclooxygenase pathways of the arachidonic acid cascade in vitro.

Journal: Prostaglandins, leukotrienes, and medicine 19860801

Title: Effects of some non-steroidal anti-inflammatory drugs and other agents on cyclooxygenase and lipoxygenase activities in some enzyme preparations.

Journal: Japanese journal of pharmacology 19850601

Title: Inhibition of steroid production in Leydig cells by non-steroidal anti-inflammatory and related compounds: evidence for the involvement of lipoxygenase products in steroidogenesis.

Journal: The Biochemical journal 19840415

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Tags:66000-40-6 Molecular Formula|66000-40-6 MDL|66000-40-6 SMILES|66000-40-6 1-[3-(Trifluoromethyl)phenyl]-4,5-dihydro-1h-pyrazol-3-amine