79916-77-1,MFCD08460220
Catalog No.:AA00G2DP

79916-77-1 | Forsythoside a

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5mg
≥98%
in stock  
$70.00   $49.00
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10mg
≥98%
in stock  
$132.00   $92.00
- +
25mg
≥98%
in stock  
$240.00   $168.00
- +
50mg
≥98%
in stock  
$443.00   $310.00
- +
1000mg
98% by HPLC
in stock  
$8,372.00   $5,860.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00G2DP
Chemical Name:
Forsythoside a
CAS Number:
79916-77-1
Molecular Formula:
C29H36O15
Molecular Weight:
624.5871
MDL Number:
MFCD08460220
SMILES:
O=C(O[C@@H]1[C@@H](CO[C@@H]2O[C@@H](C)[C@@H]([C@H]([C@H]2O)O)O)O[C@H]([C@@H]([C@H]1O)O)OCCc1ccc(c(c1)O)O)/C=C/c1ccc(c(c1)O)O
NSC Number:
729638
Properties
Computed Properties
 
Complexity:
936  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
10  
Defined Bond Stereocenter Count:
1  
Formal Charge:
0  
Heavy Atom Count:
44  
Hydrogen Bond Acceptor Count:
15  
Hydrogen Bond Donor Count:
9  
Isotope Atom Count:
0  
Rotatable Bond Count:
11  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-0.5  

Downstream Synthesis Route

[1]Nishibe;Okabe;Tsukamoto;etal.[ChemicalandPharmaceuticalBulletin,1982,vol.30,#3,p.1048-1050]

[1]Nishibe;Okabe;Tsukamoto;etal.[ChemicalandPharmaceuticalBulletin,1982,vol.30,#3,p.1048-1050]

79916-77-1   
Methylcaffeate 
  93675-88-8 

[1]Endo;Hikino[CanadianJournalofChemistry,1984,vol.62,#10,p.2011-2014]

[2]Endo;Hikino[CanadianJournalofChemistry,1984,vol.62,#10,p.2011-2014]

3,4-dihydroxy-β-phenethyl-O-β-D-glucopyranosyl-(1->3)-O-α-rhamnopyranosyl-(1->6)-4-caffeoyl-β-D-glucopyranoside 
  104777-68-6    84744-28-5    79916-77-1 

[1]Phytochemistry,1986,vol.25,p.1633-1636

[1]Endo,Katsuya;Takahashi,Kazihuro;Abe,Toyoko;Hikino,Hiroshi[Heterocycles,1981,vol.16,#8,p.1311-1314]

Literature

Title: Intestinal absorption of forsythoside A in in situ single-pass intestinal perfusion and in vitro Caco-2 cell models.

Journal: Acta pharmacologica Sinica 20120801

Title: In vitro metabolism in Sprague-Dawley rat liver microsomes of forsythoside A in different compositions of Shuang-Huang-Lian.

Journal: Fitoterapia 20111201

Title: [Effect of habitat processing method on phillyrin and forsythiaside A of Forsythiae Fructus].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111201

Title: [Study on in situ intestinal absorption of active ingredients in Shuanghuanglian oral liquid in rats].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110701

Title: Investigation on the absorption of phillyrin and forsythiaside in rat digestive tract.

Journal: European journal of drug metabolism and pharmacokinetics 20110601

Title: [Intestinal absorption of forsythoside A by rat circulation in situ].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20101101

Title: [Studies on separation and purification of phenylethanoid glycosides from leaves of Forsythia suspensa by macroporous adsorption resin].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100901

Title: An LC-MS/MS method for the simultaneous determination of chlorogenic acid, forsythiaside A and baicalin in rat plasma and its application to pharmacokinetic study of shuang-huang-lian in rats.

Journal: Journal of pharmaceutical and biomedical analysis 20100801

Title: [Quantitative determination of forsythiaside in Forsythia suspensa].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100801

Title: Protective effects of Forsythia suspensa extract against oxidative stress induced by diquat in rats.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100201

Title: An LC-MS/MS method for determination of forsythiaside in rat plasma and application to a pharmacokinetic study.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100101

Title: Simultaneous quantification of 14 bioactive constituents in Forsythia suspensa by liquid chromatography-electrospray ionisation-mass spectrometry.

Journal: Phytochemical analysis : PCA 20100101

Title: Quantitative analysis and chromatographic fingerprinting for the quality evaluation of Forsythia suspensa extract by HPLC coupled with photodiode array detector.

Journal: Journal of separation science 20091201

Title: [Qualitative analysis of the main chemical constituents of shuanghuanglian injection powder and their origin by HPLC-ESI/MS/MS spectrometry].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20091201

Title: Selective enrichment with 'click oligo (ethylene glycol)' column and TOF-MS characterization of simple phenylpropanoids in the fruits of Forsythia suspensa.

Journal: Journal of separation science 20090901

Title: New phenylethanoid glycosides from the fruits of forsythia suspense (thunb.) vahl.

Journal: Molecules (Basel, Switzerland) 20090325

Title: Pharmacokinetics of phillyrin and forsythiaside following iv administration to Beagle dog.

Journal: European journal of drug metabolism and pharmacokinetics 20090101

Title: Antioxidant and antibacterial activity of two compounds (forsythiaside and forsythin) isolated from Forsythia suspensa.

Journal: The Journal of pharmacy and pharmacology 20080201

Title: Assessment of the antibacterial activity of phenylethanoid glycosides from Phlomis lanceolata against multiple-drug-resistant strains of Staphylococcus aureus.

Journal: Journal of natural medicines 20080101

Title: [RP-HPLC analysis of single, merging, and boiled together Lonicera japonica and Forsythia suspense].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071101

Title: [Relative adscriptions of components in the effective fractions of Yinqiao decoction and its composing individual herbs].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070201

Title: [Preparation of forsythiaside from Forsythia suspensa by high-performance liquid chromato- graphy].

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20051101

Title: Antioxidant constituents of the aerial parts of Globularia alypum growing in Morocco.

Journal: Journal of natural products 20050801

Title: [Vasorelaxant effects of forsythiaside from the fruits of Forsythia suspensa].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20050201

Title: [Determination of phillyrin and forsythoside A in Lianqiao Bingdu Qing capsule by RP-HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050101

Title: [Study on the spectral properties of caffeic acid and its derivatives].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20030201

Title: [Isolation and elucidation of chemical constituents with antiviral action from yinqiaosan on influenza virus].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030101

Title: Isolation and pharmacological activity of phenylpropanoid esters from Marrubium vulgare.

Journal: Journal of ethnopharmacology 20020301

Title: Wang Y, et al. Forsythiaside A Exhibits Anti-inflammatory Effects in LPS-Stimulated BV2 Microglia Cells Through Activation of Nrf2/HO-1 Signaling Pathway. Neurochem Res. 2016 Apr;41(4):659-65.

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Additional Info:
SDS
Tags:79916-77-1 Molecular Formula|79916-77-1 MDL|79916-77-1 SMILES|79916-77-1 Forsythoside a
Catalog No.: AA00G2DP
79916-77-1,MFCD08460220
79916-77-1 | Forsythoside a
Pack Size: 5mg
Purity: ≥98%
in stock
$70.00 $49.00
Pack Size: 10mg
Purity: ≥98%
in stock
$132.00 $92.00
Pack Size: 25mg
Purity: ≥98%
in stock
$240.00 $168.00
Pack Size: 50mg
Purity: ≥98%
in stock
$443.00 $310.00
Pack Size: 1000mg
Purity: 98% by HPLC
in stock
$8,372.00 $5,860.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00G2DP
Chemical Name: Forsythoside a
CAS Number: 79916-77-1
Molecular Formula: C29H36O15
Molecular Weight: 624.5871
MDL Number: MFCD08460220
SMILES: O=C(O[C@@H]1[C@@H](CO[C@@H]2O[C@@H](C)[C@@H]([C@H]([C@H]2O)O)O)O[C@H]([C@@H]([C@H]1O)O)OCCc1ccc(c(c1)O)O)/C=C/c1ccc(c(c1)O)O
NSC Number: 729638
Properties
Complexity: 936  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 10  
Defined Bond Stereocenter Count: 1  
Formal Charge: 0  
Heavy Atom Count: 44  
Hydrogen Bond Acceptor Count: 15  
Hydrogen Bond Donor Count: 9  
Isotope Atom Count: 0  
Rotatable Bond Count: 11  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: -0.5  
Downstream Synthesis Route
108-24-7    79916-77-1    82001-07-8 

[1]Nishibe;Okabe;Tsukamoto;etal.[ChemicalandPharmaceuticalBulletin,1982,vol.30,#3,p.1048-1050]

79916-77-1    2280-44-6    73-34-7    331-39-5    10597-60-1 

[1]Nishibe;Okabe;Tsukamoto;etal.[ChemicalandPharmaceuticalBulletin,1982,vol.30,#3,p.1048-1050]

79916-77-1   
Methylcaffeate 
  93675-88-8 

[1]Endo;Hikino[CanadianJournalofChemistry,1984,vol.62,#10,p.2011-2014]

[2]Endo;Hikino[CanadianJournalofChemistry,1984,vol.62,#10,p.2011-2014]

3,4-dihydroxy-β-phenethyl-O-β-D-glucopyranosyl-(1->3)-O-α-rhamnopyranosyl-(1->6)-4-caffeoyl-β-D-glucopyranoside 
  104777-68-6    84744-28-5    79916-77-1 

[1]Phytochemistry,1986,vol.25,p.1633-1636

79916-77-1    74-88-4    79936-06-4 

[1]Endo,Katsuya;Takahashi,Kazihuro;Abe,Toyoko;Hikino,Hiroshi[Heterocycles,1981,vol.16,#8,p.1311-1314]

Literature fold

Title: Intestinal absorption of forsythoside A in in situ single-pass intestinal perfusion and in vitro Caco-2 cell models.

Journal: Acta pharmacologica Sinica20120801

Title: In vitro metabolism in Sprague-Dawley rat liver microsomes of forsythoside A in different compositions of Shuang-Huang-Lian.

Journal: Fitoterapia20111201

Title: [Effect of habitat processing method on phillyrin and forsythiaside A of Forsythiae Fructus].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20111201

Title: [Study on in situ intestinal absorption of active ingredients in Shuanghuanglian oral liquid in rats].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20110701

Title: Investigation on the absorption of phillyrin and forsythiaside in rat digestive tract.

Journal: European journal of drug metabolism and pharmacokinetics20110601

Title: [Intestinal absorption of forsythoside A by rat circulation in situ].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20101101

Title: [Studies on separation and purification of phenylethanoid glycosides from leaves of Forsythia suspensa by macroporous adsorption resin].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20100901

Title: An LC-MS/MS method for the simultaneous determination of chlorogenic acid, forsythiaside A and baicalin in rat plasma and its application to pharmacokinetic study of shuang-huang-lian in rats.

Journal: Journal of pharmaceutical and biomedical analysis20100801

Title: [Quantitative determination of forsythiaside in Forsythia suspensa].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20100801

Title: Protective effects of Forsythia suspensa extract against oxidative stress induced by diquat in rats.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20100201

Title: An LC-MS/MS method for determination of forsythiaside in rat plasma and application to a pharmacokinetic study.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20100101

Title: Simultaneous quantification of 14 bioactive constituents in Forsythia suspensa by liquid chromatography-electrospray ionisation-mass spectrometry.

Journal: Phytochemical analysis : PCA20100101

Title: Quantitative analysis and chromatographic fingerprinting for the quality evaluation of Forsythia suspensa extract by HPLC coupled with photodiode array detector.

Journal: Journal of separation science20091201

Title: [Qualitative analysis of the main chemical constituents of shuanghuanglian injection powder and their origin by HPLC-ESI/MS/MS spectrometry].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20091201

Title: Selective enrichment with 'click oligo (ethylene glycol)' column and TOF-MS characterization of simple phenylpropanoids in the fruits of Forsythia suspensa.

Journal: Journal of separation science20090901

Title: New phenylethanoid glycosides from the fruits of forsythia suspense (thunb.) vahl.

Journal: Molecules (Basel, Switzerland)20090325

Title: Pharmacokinetics of phillyrin and forsythiaside following iv administration to Beagle dog.

Journal: European journal of drug metabolism and pharmacokinetics20090101

Title: Antioxidant and antibacterial activity of two compounds (forsythiaside and forsythin) isolated from Forsythia suspensa.

Journal: The Journal of pharmacy and pharmacology20080201

Title: Assessment of the antibacterial activity of phenylethanoid glycosides from Phlomis lanceolata against multiple-drug-resistant strains of Staphylococcus aureus.

Journal: Journal of natural medicines20080101

Title: [RP-HPLC analysis of single, merging, and boiled together Lonicera japonica and Forsythia suspense].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20071101

Title: [Relative adscriptions of components in the effective fractions of Yinqiao decoction and its composing individual herbs].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20070201

Title: [Preparation of forsythiaside from Forsythia suspensa by high-performance liquid chromato- graphy].

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA20051101

Title: Antioxidant constituents of the aerial parts of Globularia alypum growing in Morocco.

Journal: Journal of natural products20050801

Title: [Vasorelaxant effects of forsythiaside from the fruits of Forsythia suspensa].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan20050201

Title: [Determination of phillyrin and forsythoside A in Lianqiao Bingdu Qing capsule by RP-HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20050101

Title: [Study on the spectral properties of caffeic acid and its derivatives].

Journal: Guang pu xue yu guang pu fen xi = Guang pu20030201

Title: [Isolation and elucidation of chemical constituents with antiviral action from yinqiaosan on influenza virus].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20030101

Title: Isolation and pharmacological activity of phenylpropanoid esters from Marrubium vulgare.

Journal: Journal of ethnopharmacology20020301

Title: Wang Y, et al. Forsythiaside A Exhibits Anti-inflammatory Effects in LPS-Stimulated BV2 Microglia Cells Through Activation of Nrf2/HO-1 Signaling Pathway. Neurochem Res. 2016 Apr;41(4):659-65.

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