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80451-05-4,MFCD00130753
Catalog No.:AA00G2M1

80451-05-4 | CECROPIN B

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1mg
≥97% (HPLC)
in stock  
$332.00   $233.00
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2mg
≥97% (HPLC)
in stock  
$554.00   $388.00
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5mg
≥97% (HPLC)
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$884.00   $619.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G2M1
Chemical Name:
CECROPIN B
CAS Number:
80451-05-4
Molecular Formula:
C176H302N52O41S
Molecular Weight:
3834.6699
MDL Number:
MFCD00130753
SMILES:
NCCCCC(C(=O)NC(C(=O)NCC(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N)CC(C)C)C)CCCCN)C)CCC(=O)O)CC(C)C)C(C)C)C)C(CC)C)C)C)NC(=O)C(C(C)C)NC(=O)C(C(CC)C)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(C(CC)C)NC(=O)C(NC(=O)C(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(C(CC)C)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(C(C)C)NC(=O)C(NC(=O)C(Cc1c[nH]c2c1cccc2)NC(=O)C(CCCCN)N)CCCCN)Cc1ccccc1)CCCCN)CCCCN)CCC(=O)O)CCCCN)CCSC)CCCNC(=N)N)CC(=O)N)CCCNC(=N)N)CC(=O)N
Properties
Computed Properties
 
Complexity:
8830  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
35  
Heavy Atom Count:
270  
Hydrogen Bond Acceptor Count:
52  
Hydrogen Bond Donor Count:
53  
Rotatable Bond Count:
138  
XLogP3:
-8.4  

Literature

Title: Comparative mode of action of novel hybrid peptide CS-1a and its rearranged amphipathic analogue CS-2a.

Journal: The FEBS journal 20121001

Title: Alternating release of different bioactive molecules from a complexation polymer system.

Journal: Biomaterials 20080901

Title: Antimicrobial peptides of the Cecropin-family show potent antitumor activity against bladder cancer cells.

Journal: BMC urology 20080101

Title: Expression of the antimicrobial peptides in plants to control phytopathogenic bacteria and fungi.

Journal: Plant cell reports 20060601

Title: Rhizosphere bacteria affected by transgenic potatoes with antibacterial activities compared with the effects of soil, wild-type potatoes, vegetation stage and pathogen exposure.

Journal: FEMS microbiology ecology 20060501

Title: Effects of cecropin-XJ on growth and adherence of oral cariogenic bacteria in vitro.

Journal: Chinese medical journal 20050120

Title: Induction of transient ion channel-like pores in a cancer cell by antibiotic peptide.

Journal: Journal of biochemistry 20040801

Title: An entomopathogenic bacterium, Xenorhabdus nematophila, inhibits the expression of an antibacterial peptide, cecropin, of the beet armyworm, Spodoptera exigua.

Journal: Journal of insect physiology 20040601

Title: Cecropin B enhances betalactams activities in experimental rat models of gram-negative septic shock.

Journal: Annals of surgery 20040201

Title: Involvement of the JNK-like protein of the Aedes albopictus mosquito cell line, C6/36, in phagocytosis, endocytosis and infection of West Nile virus.

Journal: Insect molecular biology 20031001

Title: cDNA cloning, characterization and gene expression of nitric oxide synthase from the silkworm, Bombyx mori.

Journal: Insect molecular biology 20020601

Title: Effect of mono-dose intraperitoneal cecropins in experimental septic shock.

Journal: Critical care medicine 20010901

Title: Cecropins, antibacterial peptides from insects and mammals, are potently fungicidal against Candida albicans.

Journal: Medical microbiology and immunology 20010401

Title: Kinetics of membrane lysis by custom lytic peptides and peptide orientations in membrane.

Journal: European journal of biochemistry 20010301

Title: All-D-cecropin B: synthesis, conformation, lipopolysaccharide binding, and antibacterial activity.

Journal: Molecular and cellular biochemistry 20010201

Title: Antifungal peptides: novel therapeutic compounds against emerging pathogens.

Journal: Antimicrobial agents and chemotherapy 19990101

Title: Fungicidal and binding properties of the natural peptides cecropin B and dermaseptin.

Journal: Medical mycology 19981001

Title: Zhou X et al. Cecropin B Represses CYP3A29 Expression through Activation of the TLR2/4-NF-κB/PXR Signaling Pathway. Sci Rep. 2016 Jun 14

Title: Ren HT et al. [The antibacterial effect of cecropin B on pseudomonas aeruginosa infection of wounds in miceZhonghua Shao Shang Za Zhi. 2006 Dec;22(6):445-7.

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