Title: Upregulation of hydroxysteroid sulfotransferase 2B1b promotes hepatic oval cell proliferation by modulating oxysterol-induced LXR activation in a mouse model of liver injury.
Journal: Archives of toxicology 20170101
Title: Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis.
Journal: Nature chemical biology 20130201
Title: The endogenous regulator 24(S),25-epoxycholesterol inhibits cholesterol synthesis at DHCR24 (Seladin-1).
Journal: Biochimica et biophysica acta 20120901
Title: Liver X receptors agonists impede hepatitis C virus infection in an Idol-dependent manner.
Journal: Antiviral research 20120901
Title: [Research progress of liver X receptor agonists].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20120401
Title: Mast cell death induced by 24(S),25-epoxycholesterol.
Journal: Experimental cell research 20101115
Title: Low-density lipoprotein and oxysterols suppress the transcription of CTP: Phosphoethanolamine cytidylyltransferase in vitro.
Journal: Biochimica et biophysica acta 20100401
Title: Enhanced steatosis by nuclear receptor ligands: a study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profile.
Journal: Chemico-biological interactions 20100330
Title: LXR-activating oxysterols induce the expression of inflammatory markers in endothelial cells through LXR-independent mechanisms.
Journal: Atherosclerosis 20091101
Title: Ligand, receptor, and cell type-dependent regulation of ABCA1 and ABCG1 mRNA in prostate cancer epithelial cells.
Journal: Molecular cancer therapeutics 20090701
Title: Oxysterols: Sources, cellular storage and metabolism, and new insights into their roles in cholesterol homeostasis.
Journal: Molecular aspects of medicine 20090601
Title: 24(S),25-epoxycholesterol: a messenger for cholesterol homeostasis.
Journal: The international journal of biochemistry & cell biology 20090401
Title: Epoxycholesterol impairs cholesteryl ester hydrolysis in macrophage foam cells, resulting in decreased cholesterol efflux.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20080601
Title: Ligand specificity and evolution of liver X receptors.
Journal: The Journal of steroid biochemistry and molecular biology 20080501
Title: Combination of virtual screening and high throughput gene profiling for identification of novel liver X receptor modulators.
Journal: Journal of medicinal chemistry 20080410
Title: Endogenous 24(S),25-epoxycholesterol fine-tunes acute control of cellular cholesterol homeostasis.
Journal: The Journal of biological chemistry 20080111
Title: [Synthesis of sterols oxygenated in the terminal fragment of their side chains].
Journal: Bioorganicheskaia khimiia 20080101
Title: Primary human astrocytes produce 24(S),25-epoxycholesterol with implications for brain cholesterol homeostasis.
Journal: Journal of neurochemistry 20071201
Title: Regulation of CYP3A4 and CYP2B6 expression by liver X receptor agonists.
Journal: Biochemical pharmacology 20071115
Title: Studies on the cholesterol-free mouse: strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20071001
Title: 9-cis-Retinoic acid (9cRA), a retinoid X receptor (RXR) ligand, exerts immunosuppressive effects on dendritic cells by RXR-dependent activation: inhibition of peroxisome proliferator-activated receptor gamma blocks some of the 9cRA activities, and precludes them to mature phenotype development.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20070515
Title: Selective up-regulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol.
Journal: The Journal of biological chemistry 20070223
Title: SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR.
Journal: The Biochemical journal 20061215
Title: Discovery and optimization of a novel series of liver X receptor-alpha agonists.
Journal: Bioorganic & medicinal chemistry letters 20060315
Title: [Synthesis of (24S)-hydroxy- and (24S)-24,25-epoxycholesterol analogues, potential agonists of nuclear LXR receptors].
Journal: Bioorganicheskaia khimiia 20060101
Title: Adipocytic differentiation and liver x receptor pathways regulate the accumulation of triacylglycerols in human vascular smooth muscle cells.
Journal: The Journal of biological chemistry 20050204
Title: Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20041201
Title: 24(S),25-epoxycholesterol--a potential friend.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20041201
Title: Enhanced synthesis of the oxysterol 24(S),25-epoxycholesterol in macrophages by inhibitors of 2,3-oxidosqualene:lanosterol cyclase: a novel mechanism for the attenuation of foam cell formation.
Journal: Circulation research 20031017
Title: Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist.
Journal: The Journal of biological chemistry 20030919
Title: X-ray crystal structure of the liver X receptor beta ligand binding domain: regulation by a histidine-tryptophan switch.
Journal: The Journal of biological chemistry 20030718
Title: Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines.
Journal: Journal of medicinal chemistry 20020509
Title: Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis.
Journal: The Journal of investigative dermatology 20020101
Title: Key regulatory oxysterols in liver: analysis as delta4-3-ketone derivatives by HPLC and response to physiological perturbations.
Journal: Journal of lipid research 20010401
Title: Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha.
Journal: Journal of medicinal chemistry 20010315
Title: Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19990105
Title: Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway.
Journal: The Journal of biological chemistry 19970207
