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77029-83-5,MFCD00467740
Catalog No.:AA00G365

77029-83-5 | Hypocrellin A

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1mg
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5mg
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10mg
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25mg
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50mg
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1000mg
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G365
Chemical Name:
Hypocrellin A
CAS Number:
77029-83-5
Molecular Formula:
C30H26O10
Molecular Weight:
546.5214
MDL Number:
MFCD00467740
SMILES:
COc1c(O)c2C(=O)C=C(c3c2c2c1CC(C)(O)C(c1c2c2c3C(=CC(=O)c2c(c1OC)O)OC)C(=O)C)OC
NSC Number:
635470
Properties
Computed Properties
 
Complexity:
1180  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
40  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
2  
XLogP3:
4  

Literature

Title: Development of an HPLC method to analyze and prepare elsinochrome C and hypocrellin A in the submerged fermentation broth of Shiria sp. SUPER-H168.

Journal: Biomedical chromatography : BMC 20120601

Title: Synthesis and photophysical properties of a supramolecular host-guest assembly constructed by fullerenes and tryptamine modified hypocrellin.

Journal: The journal of physical chemistry. B 20120223

Title: [Simultaneous determination of hypocrellin A, hypocrellin B, and hypocrellin C by HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120101

Title: Cerebrospinal fluid hypocretin (orexin) levels are elevated by play but are not raised by exercise and its associated heart rate, blood pressure, respiration or body temperature changes.

Journal: Archives italiennes de biologie 20111107

Title: Graphene oxide noncovalent photosensitizer and its anticancer activity in vitro.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20111017

Title: Induction of hypocrellin production by Triton X-100 under submerged fermentation with Shiraia sp. SUPER-H168.

Journal: New biotechnology 20111001

Title: Photodynamic antimicrobial activity of hypocrellin A.

Journal: Journal of photochemistry and photobiology. B, Biology 20110404

Title: Delivering a hydrophobic anticancer drug for photodynamic therapy by amorphous formulation.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: A molecular logic gate for the highly selective recognition of pyrophosphate with a hypocrellin A-Zn(II) complex.

Journal: The Analyst 20101101

Title: Mitochondria-targeting photosensitizer-encapsulated amorphous nanocage as a bimodal reagent for drug delivery and biodiagnose in vitro.

Journal: Biomedical microdevices 20100801

Title: A nanoencapsulated hypocrellin A prepared by an improved microemulsion method for photodynamic treatment.

Journal: Journal of materials science. Materials in medicine 20100701

Title: Toxicity and phototoxicity of Hypocrellin A on malignant human cell lines, evidence of a synergistic action of photodynamic therapy with Imatinib mesylate.

Journal: Journal of photochemistry and photobiology. B, Biology 20100503

Title: High-yield hypocrellin A production in solid-state fermentation by Shiraia sp. SUPER-H168.

Journal: Applied biochemistry and biotechnology 20100401

Title: [Cluster analysis on hypocrellin A content in anamorphs of Shiraia bambusicola].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100401

Title: A new sol-gel silica nanovehicle preparation for photodynamic therapy in vitro.

Journal: International journal of pharmaceutics 20100215

Title: Synthesis of the cores of hypocrellin and shiraiachrome: diastereoselective 1,8-diketone aldol cyclization.

Journal: The Journal of organic chemistry 20100101

Title: Perylenequinone natural products: total synthesis of hypocrellin A.

Journal: The Journal of organic chemistry 20100101

Title: Novel surfactant-like hypocrellin derivatives to achieve simultaneous drug delivery in blood plasma and cell uptake.

Journal: Photochemistry and photobiology 20100101

Title: Spectroscopic studies on the interaction of hypocrellin A and hemoglobin.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090201

Title: Isolation and identification of a new hypocrellin A-producing strain Shiraia sp. SUPER-H168.

Journal: Microbiological research 20090101

Title: Photosensitizer effects on cancerous cells: a combined study using synchrotron infrared and fluorescence microscopies.

Journal: Biochimica et biophysica acta 20080501

Title: Dynamic stereochemistry transfer in a transannular aldol reaction: total synthesis of hypocrellin A.

Journal: Angewandte Chemie (International ed. in English) 20080101

Title: Photodynamic properties of hypocrellin A, complexes with rare Earth trivalent ions: role of the excited state energies of the metal ions.

Journal: The journal of physical chemistry. B 20070315

Title: Effects of hypocrellin A on expression of vascular endothelial growth factor and endothelin-1 in human umbilical endothelial cells.

Journal: The American journal of Chinese medicine 20070101

Title: [Study on interaction between hypocrellin A and hemoglobin or myoglobin using synchronous fluorescence spectra].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20061201

Title: Anion of hypericin is crucial to understanding the photosensitive features of the pigment.

Journal: Bioorganic & medicinal chemistry letters 20060301

Title: Perylenequinones in photodynamic therapy: cellular versus vascular response.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20060101

Title: [Studies on liquid fermentation of anamorph of Shiraia bambusicola].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20051201

Title: Effect of chelation to lanthanum ions on the photodynamic properties of hypocrellin A.

Journal: The journal of physical chemistry. B 20051020

Title: High glucose-induced human umbilical vein endothelial cell hyperpermeability is dependent on protein kinase C activation and independent of the Ca2+-nitric oxide signalling pathway.

Journal: Clinical and experimental pharmacology & physiology 20050901

Title: Antimicrobial and antileishmanial activities of hypocrellins A and B.

Journal: Antimicrobial agents and chemotherapy 20041101

Title: Hypocrellin derivative with improvements of red absorption and active oxygen species generation.

Journal: Bioorganic & medicinal chemistry letters 20040322

Title: Reduction of high glucose and phorbol-myristate-acetate-induced endothelial cell permeability by protein kinase C inhibitors LY379196 and hypocrellin A.

Journal: Biochemical pharmacology 20040301

Title: Photodynamic treatment and H2O2-induced oxidative stress result in different patterns of cellular protein oxidation.

Journal: European journal of biochemistry 20031201

Title: Studies on the synthesis of two hydrophilic hypocrellin derivatives with enhanced absorption in the red spectral region and on their photogeneration of O2*- and O2(1(delta)g).

Journal: Journal of photochemistry and photobiology. B, Biology 20031015

Title: Synthesis and characterization of three novel amphiphilic aminated hypocrellins as photodynamic therapeutic agents.

Journal: Photochemistry and photobiology 20031001

Title: Photodynamic inhibitory effects of three perylenequinones on human colorectal carcinoma cell line and primate embryonic stem cell line.

Journal: World journal of gastroenterology 20030315

Title: First synthesis of methylated hypocrellin and its fluorescent excited state: a cautionary tale.

Journal: The Journal of organic chemistry 20030307

Title: Inhibitory effect of hypocrellin A on protein kinase C in liver and skeletal muscle of obese Zucker rats.

Journal: The American journal of Chinese medicine 20030101

Title: Efficacy of hypocrellin pharmacokinetics in phototherapy.

Journal: International journal of oncology 20021201

Title: Release of regulators of angiogenesis following Hypocrellin-A and -B photodynamic therapy of human brain tumor cells.

Journal: Biochemical and biophysical research communications 20021108

Title: Two-photon excitation studies of hypocrellins for photodynamic therapy.

Journal: Journal of photochemistry and photobiology. B, Biology 20021101

Title: Hypocrellins and Hypericin induced apoptosis in human tumor cells: a possible role of hydrogen peroxide.

Journal: International journal of molecular medicine 20020501

Title: Photodynamic therapy induced Fas-mediated apoptosis in human carcinoma cells.

Journal: International journal of molecular medicine 20020301

Title: Experimental photodynamic effects of hypocrellin A on the choriocapillaris.

Journal: Ophthalmic surgery and lasers 20020101

Title: Apoptosis induced by photosensitizers (Perylquinone derivatives) in human carcinoma cells: a possible relevance to photodynamic therapy.

Journal: Asian journal of surgery 20020101

Title: Hypericin and hypocrellin induced apoptosis in human mucosal carcinoma cells.

Journal: Journal of photochemistry and photobiology. B, Biology 20011201

Title: Photodynamic-induced apoptosis of human nasopharyngeal carcinoma cells using Hypocrellins.

Journal: International journal of oncology 20010901

Title: Photosensitization of hypomycin B--a novel perylenequinonoid pigment with only one intramolecular hydrogen bond.

Journal: Photochemistry and photobiology 20010801

Title: [Study on the detaining effect of hypocrelin a in the cancer cell using microspectrum].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20010401

Title: Dang L, et al. Effects of hypocrellin A on expression of vascular endothelial growth factor and endothelin-1 in human umbilical endothelial cells. Am J Chin Med. 2007;35(4):713-23.

Title: Ma YJ, et al. Enhanced Production of Hypocrellin A in Submerged Cultures of Shiraia bambusicola by Red Light. Photochem Photobiol. 2019 May;95(3):812-822.

Title: Fehr MJ, et al. Roles of oxygen and photoinduced acidification in the light-dependent antiviral activity of hypocrellin A. Biochemistry. 1995 Dec 5;34(48):15845-8.

Title: Ma G, et al. Antimicrobial and antileishmanial activities of hypocrellins A and B. Antimicrob Agents Chemother. 2004 Nov;48(11):4450-2.

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