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Title: A phase I study of E7080, a multitargeted tyrosine kinase inhibitor, in patients with advanced solid tumours.
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Title: Unique metabolic pathway of [(14)C]lenvatinib after oral administration to male cynomolgus monkey.
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Title: Development and validation of LC-MS/MS assays for the quantification of E7080 and metabolites in various human biological matrices.
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Title: Antitumour activity of oral E7080, a novel inhibitor of multiple tyrosine kinases, in human sarcoma xenografts.
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Title: E7080 suppresses hematogenous multiple organ metastases of lung cancer cells with nonmutated epidermal growth factor receptor.
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Title: A model of hypertension and proteinuria in cancer patients treated with the anti-angiogenic drug E7080.
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Title: E7080, a multi-tyrosine kinase inhibitor, suppresses the progression of malignant pleural mesothelioma with different proangiogenic cytokine production profiles.
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Title: Multi-kinase inhibitor E7080 suppresses lymph node and lung metastases of human mammary breast tumor MDA-MB-231 via inhibition of vascular endothelial growth factor-receptor (VEGF-R) 2 and VEGF-R3 kinase.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080901
Title: E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition.
Journal: International journal of cancer 20080201
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