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84692-91-1,MFCD11519463
Catalog No.:AA00G3KQ

84692-91-1 | Arglabin

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$132.00   $92.00
- +
5mg
≥98%
in stock  
$543.00   $380.00
- +
10mg
95%
in stock  
$681.00   $477.00
- +
25mg
95%
in stock  
$1,220.00   $854.00
- +
50mg
95%
in stock  
$1,919.00   $1,343.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G3KQ
Chemical Name:
Arglabin
CAS Number:
84692-91-1
Molecular Formula:
C15H18O3
Molecular Weight:
246.3016
MDL Number:
MFCD11519463
SMILES:
CC1=CC[C@]23[C@H]1[C@H]1OC(=O)C(=C)[C@@H]1CC[C@@]3(O2)C
Properties
Computed Properties
 
Complexity:
506  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
3  
XLogP3:
1.7  

Literature

Title: Guaianolide sesquiterpene lactones, a source to discover agents that selectively inhibit acute myelogenous leukemia stem and progenitor cells.

Journal: Journal of medicinal chemistry 20121025

Title: Biomimetic semisynthesis of arglabin from parthenolide.

Journal: The Journal of organic chemistry 20120817

Title: Synthesis and biological evaluation of antitumor-active arglabin derivatives.

Journal: Archiv der Pharmazie 20120301

Title: [Problems in the current target therapy of malignancies].

Journal: Voprosy onkologii 20050101

Title: [Anti-inflammatory effect of arglabin and 11,13-dihydro-13-dimethylaminoarglabin hydrochloride].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20040101

Title: Arglabin-DMA, a plant derived sesquiterpene, inhibits farnesyltransferase.

Journal: Oncology reports 20010101

Title: Abderrazak A, et al. Anti-inflammatory and antiatherogenic effects of the NLRP3 inflammasome inhibitor arglabin in ApoE2.Ki mice fed a high-fat diet. Circulation. 2015;131(12):1061-1070.

Title: Lone SH, et al. Arglabin: From isolation to antitumor evaluation. Chem Biol Interact. 2015;240:180-198.

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SDS
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