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841301-32-4,MFCD19443709
Catalog No.:AA00G7AT

841301-32-4 | ASP 2151

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98+%
in stock  
$76.00   $53.00
- +
25mg
98+%
in stock  
$195.00   $136.00
- +
100mg
95%
in stock  
$601.00   $421.00
- +
250mg
95%
in stock  
$1,155.00   $809.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00G7AT
Chemical Name:
ASP 2151
CAS Number:
841301-32-4
Molecular Formula:
C24H26N4O5S
Molecular Weight:
482.5520
MDL Number:
MFCD19443709
SMILES:
O=C(CN(c1c(C)cccc1C)C(=O)C1CCS(=O)(=O)CC1)Nc1ccc(cc1)c1nocn1
Properties
Computed Properties
 
Complexity:
800  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
2.6  

Literature

Title: Efficacy of herpes virus helicase-primase inhibitor, ASP2151, for treating herpes simplex keratitis in mouse model.

Journal: The British journal of ophthalmology 20130401

Title: Synergistic activity of amenamevir (ASP2151) with nucleoside analogs against herpes simplex virus types 1 and 2 and varicella-zoster virus.

Journal: Antiviral research 20130201

Title: ASP2151 for the treatment of genital herpes: a randomized, double-blind, placebo- and valacyclovir-controlled, dose-finding study.

Journal: The Journal of infectious diseases 20120401

Title: Efficacy of ASP2151, a helicase-primase inhibitor, against thymidine kinase-deficient herpes simplex virus type 2 infection in vitro and in vivo.

Journal: Antiviral research 20120201

Title: Effect of ASP2151, a herpesvirus helicase-primase inhibitor, in a guinea pig model of genital herpes.

Journal: Molecules (Basel, Switzerland) 20110825

Title: ASP2151, a novel helicase-primase inhibitor, possesses antiviral activity against varicella-zoster virus and herpes simplex virus types 1 and 2.

Journal: The Journal of antimicrobial chemotherapy 20100801

Title: Katsumata K, et al. Pharmacokinetics and pharmacodynamics of ASP2151, a helicase-primase inhibitor, in a murine model of herpes simplex virus infection. Antimicrob Agents Chemother. 2013 Mar;57(3):1339-46.

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SDS
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 1282459-39-5

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Tags:841301-32-4 Molecular Formula|841301-32-4 MDL|841301-32-4 SMILES|841301-32-4 ASP 2151
Catalog No.: AA00G7AT
841301-32-4,MFCD19443709
841301-32-4 | ASP 2151
Pack Size： 5mg
Purity： 98+%
in stock
$76.00 $53.00
Pack Size： 25mg
Purity： 98+%
in stock
$195.00 $136.00
Pack Size： 100mg
Purity： 95%
in stock
$601.00 $421.00
Pack Size： 250mg
Purity： 95%
in stock
$1,155.00 $809.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00G7AT
Chemical Name: ASP 2151
CAS Number: 841301-32-4
Molecular Formula: C24H26N4O5S
Molecular Weight: 482.5520
MDL Number: MFCD19443709
SMILES: O=C(CN(c1c(C)cccc1C)C(=O)C1CCS(=O)(=O)CC1)Nc1ccc(cc1)c1nocn1
Properties
Complexity: 800  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 34  
Hydrogen Bond Acceptor Count: 7  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 6  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 2.6  
Literature fold

Title: Efficacy of herpes virus helicase-primase inhibitor, ASP2151, for treating herpes simplex keratitis in mouse model.

Journal: The British journal of ophthalmology20130401

Title: Synergistic activity of amenamevir (ASP2151) with nucleoside analogs against herpes simplex virus types 1 and 2 and varicella-zoster virus.

Journal: Antiviral research20130201

Title: ASP2151 for the treatment of genital herpes: a randomized, double-blind, placebo- and valacyclovir-controlled, dose-finding study.

Journal: The Journal of infectious diseases20120401

Title: Efficacy of ASP2151, a helicase-primase inhibitor, against thymidine kinase-deficient herpes simplex virus type 2 infection in vitro and in vivo.

Journal: Antiviral research20120201

Title: Effect of ASP2151, a herpesvirus helicase-primase inhibitor, in a guinea pig model of genital herpes.

Journal: Molecules (Basel, Switzerland)20110825

Title: ASP2151, a novel helicase-primase inhibitor, possesses antiviral activity against varicella-zoster virus and herpes simplex virus types 1 and 2.

Journal: The Journal of antimicrobial chemotherapy20100801

Title: Katsumata K, et al. Pharmacokinetics and pharmacodynamics of ASP2151, a helicase-primase inhibitor, in a murine model of herpes simplex virus infection. Antimicrob Agents Chemother. 2013 Mar;57(3):1339-46.

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