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Home Other Building Blocks 864082-47-3
864082-47-3,MFCD16618404
Catalog No.:AA00GRS2

864082-47-3 | GSK429286A

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$17.00   $12.00
- +
5mg
98%
in stock  
$41.00   $29.00
- +
10mg
98%
in stock  
$60.00   $42.00
- +
25mg
98%
in stock  
$100.00   $70.00
- +
50mg
98%
in stock  
$169.00   $118.00
- +
100mg
98%
in stock  
$285.00   $199.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00GRS2
Chemical Name:
GSK429286A
CAS Number:
864082-47-3
Molecular Formula:
C21H16F4N4O2
Molecular Weight:
432.3710
MDL Number:
MFCD16618404
SMILES:
O=C1NC(=C(C(C1)c1ccc(cc1)C(F)(F)F)C(=O)Nc1cc2cn[nH]c2cc1F)C
Properties
Computed Properties
 
Complexity:
748  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
1  
XLogP3:
2.9  

Literature

Title: Development of dihydropyridone indazole amides as selective Rho-kinase inhibitors.

Journal: Journal of medicinal chemistry 20070111

Title: Goodman KB et al Development of dihydropyridone indazole amides as selective Rho-kinase inhibitors. J Med Chem. 2007 Jan 11;50(1):6-9.

Title: Nichols RJ et al Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's disease. Biochem J. 2009 Oct 23;424(1):47-60.

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SDS
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Tags:864082-47-3 Molecular Formula|864082-47-3 MDL|864082-47-3 SMILES|864082-47-3 GSK429286A