Home Other Building Blocks 88373-73-3
88373-73-3,MFCD00076430
Catalog No.:AA00GRXX

88373-73-3 | DPDPE

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
1 week  
$209.00   $147.00
- +
5mg
98%
1 week  
$495.00   $347.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00GRXX
Chemical Name:
DPDPE
CAS Number:
88373-73-3
Molecular Formula:
C30H39N5O7S2
Molecular Weight:
645.7900
MDL Number:
MFCD00076430
SMILES:
O=C1CNC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(cc2)O)N)C(C)(C)SSC([C@H](NC(=O)[C@@H](N1)Cc1ccccc1)C(=O)O)(C)C
Properties
Computed Properties
 
Complexity:
1040  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
44  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
7  
Rotatable Bond Count:
7  
XLogP3:
-0.6  

Literature

Title: Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators.

Journal: Journal of the American Chemical Society 20160601

Title: Optimized Hepatocyte-Like Cells with Functional Drug Transporters Directly-Reprogrammed from Mouse Fibroblasts and their Potential in Drug Disposition and Toxicology.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20160101

Title: Orally active opioid μ/δ dual agonist MGM-16, a derivative of the indole alkaloid mitragynine, exhibits potent antiallodynic effect on neuropathic pain in mice.

Journal: The Journal of pharmacology and experimental therapeutics 20140301

Title: Treatment with carbon monoxide-releasing molecules and an HO-1 inducer enhances the effects and expression of µ-opioid receptors during neuropathic pain.

Journal: Anesthesiology 20130501

Title: Selective interactions of spinophilin with the C-terminal domains of the δ- and μ-opioid receptors and G proteins differentially modulate opioid receptor signaling.

Journal: Cellular signalling 20121201

Title: Influence of corticostriatal δ-opioid receptors on abnormal involuntary movements induced by L-DOPA in hemiparkinsonian rats.

Journal: Experimental neurology 20120801

Title: Alcohol self-administration, anxiety, and cortisol levels predict changes in delta opioid receptor function in the ventral tegmental area.

Journal: Behavioral neuroscience 20120801

Title: The inhibition of the nitric oxide-cGMP-PKG-JNK signaling pathway avoids the development of tolerance to the local antiallodynic effects produced by morphine during neuropathic pain.

Journal: European journal of pharmacology 20120615

Title: Cannabinoid CB1 receptor activation, pharmacological blockade, or genetic ablation affects the function of the muscarinic auto- and heteroreceptor.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120401

Title: ßarrestin1-biased agonism at human δ-opioid receptor by peptidic and alkaloid ligands.

Journal: Cellular signalling 20120301

Title: Opioidergic modulation of ethanol self-administration in the ventral pallidum.

Journal: Alcoholism, clinical and experimental research 20120201

Title: Delta-opioid augments cardiac contraction through β-adrenergic and CGRP-receptor co-signaling.

Journal: Peptides 20120101

Title: [Role of dopamine D1- and D2-receptors in the delta1-opioidergic immunostimulation].

Journal: Vestnik Rossiiskoi akademii meditsinskikh nauk 20120101

Title: The effect of intrathecal mu, delta, kappa, and alpha-2 agonists on thermal hyperalgesia induced by mild burn on hind paw in rats.

Journal: Journal of anesthesia 20111201

Title: Dorsal hippocampal N-methyl-D-aspartate glutamatergic and δ-opioidergic systems modulate anxiety behaviors in rats in a noninteractive manner.

Journal: The Kaohsiung journal of medical sciences 20111101

Title: Structural determinants of opioid and NOP receptor activity in derivatives of buprenorphine.

Journal: Journal of medicinal chemistry 20111013

Title: Activation of peripheral delta-opioid receptors leads to anti-hyperalgesic responses in the masseter muscle of male and female rats.

Journal: Neuroscience 20110908

Title: The expression of genes encoding opioid precursors and the influence of opioid receptor agonists on steroidogenesis in porcine adrenocortical cells in vitro.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110801

Title: Opioid-induced down-regulation of RGS4: role of ubiquitination and implications for receptor cross-talk.

Journal: The Journal of biological chemistry 20110311

Title: Involvement of peripheral mu opioid receptors in scratching behavior in mice.

Journal: European journal of pharmacology 20101215

Title: Serine 363 of the {delta}-opioid receptor is crucial for adopting distinct pathways to activate ERK1/2 in response to stimulation with different ligands.

Journal: Journal of cell science 20101215

Title: A role for delta opioid receptors in the central nucleus of the amygdala in anxiety-like behaviors.

Journal: Psychopharmacology 20101201

Title: Dorsal hippocampal opioidergic system modulates anxiety-like behaviors in adult male Wistar rats.

Journal: Psychiatry and clinical neurosciences 20101201

Title: Consequences of opioid receptor mutation on actions of univalent and bivalent kappa and delta ligands.

Journal: Psychopharmacology 20100601

Title: Evaluation of the endothelin receptor antagonists ambrisentan, darusentan, bosentan, and sitaxsentan as substrates and inhibitors of hepatobiliary transporters in sandwich-cultured human hepatocytes.

Journal: Canadian journal of physiology and pharmacology 20100601

Title: Cloning/characterization of the canine organic anion transporting polypeptide 1b4 (Oatp1b4) and classification of the canine OATP/SLCO members.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20100401

Title: Standard opioid agonists activate heteromeric opioid receptors: evidence for morphine and [d-Ala(2)-MePhe(4)-Glyol(5)]enkephalin as selective μ-δ agonists.

Journal: ACS chemical neuroscience 20100217

Title: Functional characterization of mouse organic anion transporting peptide 1a4 in the uptake and efflux of drugs across the blood-brain barrier.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100101

Title: Kappa2 opioid receptor subtype binding requires the presence of the DOR-1 gene.

Journal: Frontiers in bioscience (Scholar edition) 20100101

Title: Delta opioid receptor on equine sperm cells: subcellular localization and involvement in sperm motility analyzed by computer assisted sperm analyzer (CASA).

Journal: Reproductive biology and endocrinology : RB&E 20100101

Title: Reducing ischaemia/reperfusion injury through delta-opioid-regulated intrinsic cardiac adrenergic cells: adrenopeptidergic co-signalling.

Journal: Cardiovascular research 20091201

Title: Role of Intracellular Calcium and Cyclic Nucleotides in Realization of Cardioprotective Effects of δ(1)- and κ(1)-Opioid Receptor Agonists.

Journal: Bulletin of experimental biology and medicine 20091201

Title: Interactions of Na+,K+-ATPase and co-expressed delta-opioid receptor.

Journal: Neuroscience research 20091101

Title: Role of the opioid system in incentive downshift situations.

Journal: Neurobiology of learning and memory 20091001

Title: The peripheral administration of a nitric oxide donor potentiates the local antinociceptive effects of a DOR agonist during chronic inflammatory pain in mice.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20091001

Title: Effects of opioid receptor activation on thermal antinociception in red-eared slider turtles (Trachemys scripta).

Journal: American journal of veterinary research 20090901

Title: Role of mu- and delta-opioid receptors in the nucleus accumbens in cocaine-seeking behavior.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090701

Title: Delta receptors are required for full inhibitory coupling of mu-receptors to voltage-dependent Ca(2+) channels in dorsal root ganglion neurons.

Journal: Molecular pharmacology 20090701

Title: G protein independent phosphorylation and internalization of the delta-opioid receptor.

Journal: Journal of neurochemistry 20090601

Title: [Intracellular mechanisms of opioidergic regulation of the myocardial function during normoxia and postischemic reperfusion].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20090401

Title: Activation of micro, delta or kappa opioid receptors by DAMGO, DPDPE, U-50488 or U-69593 respectively causes antinociception in the formalin test in the naked mole-rat (Heterocephalus glaber).

Journal: Pharmacology, biochemistry, and behavior 20090201

Title: Peripheral delta opioid receptors require priming for functional competence in vivo.

Journal: European journal of pharmacology 20090114

Title: Src promotes delta opioid receptor (DOR) desensitization by interfering with receptor recycling.

Journal: Journal of cellular and molecular medicine 20090101

Title: Nociceptin produces antinociception after spinal administration in amphibians.

Journal: Pharmacology, biochemistry, and behavior 20090101

Title: Role of Src in ligand-specific regulation of delta-opioid receptor desensitization and internalization.

Journal: Journal of neurochemistry 20090101

Title: Inhibitory and excitatory effects of micro-, delta-, and kappa-opioid receptor activation on breathing in awake turtles, Trachemys scripta.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20081101

Title: The selective delta opioid agonist SNC80 enhances amphetamine-mediated efflux of dopamine from rat striatum.

Journal: Neuropharmacology 20081001

Title: Differential effects of opioid agonists on G protein expression in CHO cells expressing cloned human opioid receptors.

Journal: Brain research bulletin 20080905

Title: Acute delta- and kappa-opioid agonist pretreatment potentiates opioid antagonist-induced suppression of water consumption.

Journal: Brain research bulletin 20080815

Title: Removing TRPV1-expressing primary afferent neurons potentiates the spinal analgesic effect of delta-opioid agonists on mechano-nociception.

Journal: Neuropharmacology 20080801

Title: Shell/core differences in mu- and delta-opioid receptor modulation of dopamine efflux in nucleus accumbens.

Journal: Neuropharmacology 20080801

Title: Post-endocytic fates of delta-opioid receptor are regulated by GRK2-mediated receptor phosphorylation and distinct beta-arrestin isoforms.

Journal: Journal of neurochemistry 20080701

Title: Delta opioid receptors mediate chemotaxis in bone marrow-derived dendritic cells.

Journal: Journal of neuroimmunology 20080615

Title: Distinct inhibition of voltage-activated Ca2+ channels by delta-opioid agonists in dorsal root ganglion neurons devoid of functional T-type Ca2+ currents.

Journal: Neuroscience 20080602

Title: Different kinases desensitize the human delta-opioid receptor (hDOP-R) in the neuroblastoma cell line SK-N-BE upon peptidic and alkaloid agonists.

Journal: Cellular signalling 20080601

Title: Presynaptic actions of opioid receptor agonists in ventromedial hypothalamic neurons in estrogen- and oil-treated female mice.

Journal: Neuroscience 20080409

Title: Neuroprotection and functional recovery conferred by administration of kappa- and delta 1-opioid agonists in a rat model of global ischemia.

Journal: Physiology & behavior 20080227

Title: Synthesis and pharmacological characterization of a novel, highly potent, peptidomimetic delta-opioid radioantagonist, [3H]Tyr-Tic-(2S,3R)-beta-MePhe-Phe-OH.

Journal: Neuropeptides 20080201

Title: Ligand stabilization of CXCR4/delta-opioid receptor heterodimers reveals a mechanism for immune response regulation.

Journal: European journal of immunology 20080201

Title: Opioid regulation of spinal cord plasticity: evidence the kappa-2 opioid receptor agonist GR89696 inhibits learning within the rat spinal cord.

Journal: Neurobiology of learning and memory 20080101

Title: Comparison of liquid chromatography-mass spectrometry and radioimmunoassay for measurement of fentanyl and determination of pharmacokinetics in equine plasma.

Journal: Journal of analytical toxicology 20080101

Title: Opioid-induced depression in the lamprey respiratory network.

Journal: Neuroscience 20071212

Title: Influence of glial cells in the dopamine releasing effect resulting from the stimulation of striatal delta-opioid receptors.

Journal: Neuroscience 20071130

Title: Trafficking of preassembled opioid mu-delta heterooligomer-Gz signaling complexes to the plasma membrane: coregulation by agonists.

Journal: Biochemistry 20071113

Title: [Opioids and spinal analgesia].

Journal: Masui. The Japanese journal of anesthesiology 20071101

Title: Mediating delta-opioid-initiated heart protection via the beta2-adrenergic receptor: role of the intrinsic cardiac adrenergic cell.

Journal: American journal of physiology. Heart and circulatory physiology 20070701

Title: Selectivity of delta- and kappa-opioid ligands depends on the route of central administration in mice.

Journal: The Journal of pharmacology and experimental therapeutics 20070701

Title: The chemokine CX3CL1/fractalkine interferes with the antinociceptive effect induced by opioid agonists in the periaqueductal grey of rats.

Journal: Brain research 20070611

Title: Different effects of opioid antagonists on mu-, delta-, and kappa-opioid receptors with and without agonist pretreatment.

Journal: The Journal of pharmacology and experimental therapeutics 20070501

Title: Further studies of tyrosine surrogates in opioid receptor peptide ligands.

Journal: Bioorganic & medicinal chemistry letters 20070501

Title: Impaired p38 MAPK/HSP27 signaling underlies aging-related failure in opioid-mediated cardioprotection.

Journal: Journal of molecular and cellular cardiology 20070501

Title: Rapid heterologous desensitization of antinociceptive activity between mu or delta opioid receptors and chemokine receptors in rats.

Journal: Drug and alcohol dependence 20070417

Title: Involvement of endogenous opioid peptides in the antinociception induced by the novel dermorphin tetrapeptide analog amidino-TAPA.

Journal: European journal of pharmacology 20070410

Title: Delta opioids reduce the neurotransmitter release probability by enhancing transient (KV4) K+-currents in corticostriatal synapses as evaluated by the paired pulse protocol.

Journal: Neuroscience letters 20070306

Title: Effects of opioid subtypes on detrusor overactivity in rats with cerebral infarction.

Journal: International journal of urology : official journal of the Japanese Urological Association 20070301

Title: Cholesterol reduction by methyl-beta-cyclodextrin attenuates the delta opioid receptor-mediated signaling in neuronal cells but enhances it in non-neuronal cells.

Journal: Biochemical pharmacology 20070215

Title: Nociceptin/orphanin FQ blocks the antinociception induced by mu, kappa and delta opioid agonists on the cold water tail-flick test.

Journal: European journal of pharmacology 20070214

Title: Presynaptic delta opioid receptors regulate ethanol actions in central amygdala.

Journal: The Journal of pharmacology and experimental therapeutics 20070201

Title: The possible involvement of endogenous ligands for mu-, delta- and kappa-opioid receptors in modulating morphine-induced CPP expression in rats.

Journal: Peptides 20061201

Title: Differential effects of impaired mitochondrial energy production on the function of mu and delta opioid receptors in neuronal SK-N-SH cells.

Journal: Neuroscience letters 20060814

Title: Presynaptic opioid receptors on noradrenergic and serotonergic neurons in the human as compared to the rat neocortex.

Journal: British journal of pharmacology 20060701

Title: Regulation of the glutamate transporter EAAC1 by expression and activation of delta-opioid receptor.

Journal: The European journal of neuroscience 20060701

Title: Short- and long-term regulation of adenylyl cyclase activity by delta-opioid receptor are mediated by Galphai2 in neuroblastoma N2A cells.

Journal: Molecular pharmacology 20060601

Title: Reduction of lipopolysaccharide-induced interleukin-6 production by the kappa opioid U50,488 in a mouse monocyte-like cell line.

Journal: International immunopharmacology 20060601

Title: Gi-coupled receptors mediate phosphorylation of CPI-17 and MLC20 via preferential activation of the PI3K/ILK pathway.

Journal: The Biochemical journal 20060515

Title: Delta and mu opioid receptors from the brain of a urodele amphibian, the rough-skinned newt Taricha granulosa: cloning, heterologous expression, and pharmacological characterization.

Journal: General and comparative endocrinology 20060501

Title: In vivo evaluation of (+)-MR200 as a new selective sigma ligand modulating MOP, DOP and KOP supraspinal analgesia.

Journal: Life sciences 20060418

Title: Opioid receptors in the nucleus accumbens regulate attentional learning in the blocking paradigm.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060412

Title: The role of progestin receptors and the mitogen-activated protein kinase pathway in delta opioid receptor facilitation of female reproductive behaviors.

Journal: Hormones and behavior 20060401

Title: Effects of mu, kappa or delta opioids administered by pellet or pump on oral Salmonella infection and gastrointestinal transit.

Journal: European journal of pharmacology 20060318

Title: Increased opioid receptor binding and G protein coupling in the accumbens and ventral tegmental area of postnatal day 2 rats.

Journal: Neuroscience letters 20060313

Title: Opioids trigger alpha 5 beta 1 integrin-mediated monocyte adhesion.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20060201

Title: The oxyhemoglobin dissociation curve in liver cirrhosis.

Journal: Chest 20060201

Title: Presence of delta opioid receptors on a subset of hypothalamic gonadotropin releasing hormone (GnRH) neurons.

Journal: Brain research 20060127

Title: Peptidic delta opioid receptor agonists produce antidepressant-like effects in the forced swim test and regulate BDNF mRNA expression in rats.

Journal: Brain research 20060119

Title: Delta opioid agonists attenuate TAT(1-72)-induced oxidative stress in SK-N-SH cells.

Journal: Neurotoxicology 20060101

Title: Antiexudative effects of opioids and expression of kappa- and delta-opioid receptors during intestinal inflammation in mice: involvement of nitric oxide.

Journal: The Journal of pharmacology and experimental therapeutics 20060101

Title: Mu and delta, but not kappa, opioid agonists induce spastic paraparesis after a short period of spinal cord ischaemia in rats.

Journal: British journal of anaesthesia 20060101

Title: Measurement of [Ca2+]i in whole cell suspensions using fura-2.

Journal: Methods in molecular biology (Clifton, N.J.) 20060101

Title: [Delta-opioid receptor activation prevents appearance of irreversible damages of cardiomyocytes and exacerbates myocardial contractility dysfunction during ischemia and reperfusion].

Journal: Patologicheskaia fiziologiia i eksperimental'naia terapiia 20060101

Title: N-substituted cis-4a-(3-hydroxyphenyl)-8a-methyloctahydroisoquinolines are opioid receptor pure antagonists.

Journal: Journal of medicinal chemistry 20051229

Title: Hypoxia and acidosis increase the secretion of catecholamines in the neonatal rat adrenal medulla: an in vitro study.

Journal: American journal of physiology. Cell physiology 20051201

Title: A role for the distal carboxyl tails in generating the novel pharmacology and G protein activation profile of mu and delta opioid receptor hetero-oligomers.

Journal: The Journal of biological chemistry 20051118

Title: Intracerebroventricular D-Pen2, D-Pen5-enkephalin administration soon after stressor imposition influences behavioral responsivity to a subsequent stressor encounter in CD-1 mice.

Journal: Pharmacology, biochemistry, and behavior 20051101

Title: Lipid bilayers on polyacrylamide brushes for inclusion of membrane proteins.

Journal: Langmuir : the ACS journal of surfaces and colloids 20051011

Title: Activation of delta-, kappa-, and mu-opioid receptors induces phosphorylation of tuberin in transfected HEK 293 cells and native cells.

Journal: Biochemical and biophysical research communications 20050902

Title: A delta2-opioid agonist inhibits p38 MAPK and suppresses activation of murine macrophages.

Journal: The Journal of surgical research 20050901

Title: Ligand modulation of lateral segregation of a G-protein-coupled receptor into lipid microdomains in sphingomyelin/phosphatidylcholine solid-supported bilayers.

Journal: Biochemistry 20050628

Title: Subpicomolar sensing of delta-opioid receptor ligands by molecular-imprinted polymers using plasmon-waveguide resonance spectroscopy.

Journal: Analytical chemistry 20050415

Title: Inhibition by spinal mu- and delta-opioid agonists of afferent-evoked substance P release.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050406

Title: Selective effects of the delta-opioid receptor agonist DPDPE on consummatory successive negative contrast.

Journal: Behavioral neuroscience 20050401

Title: Anti-exudative effects of opioid receptor agonists in a rat model of carrageenan-induced acute inflammation of the paw.

Journal: European journal of pharmacology 20050328

Title: Heterodimerization of mu- and delta-opioid receptors occurs at the cell surface only and requires receptor-G protein interactions.

Journal: The Journal of biological chemistry 20050325

Title: Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry.

Journal: The Journal of biological chemistry 20050311

Title: Comparison of peptidic and nonpeptidic delta-opioid agonists on guanosine 5'-O-(3-[35S]thio)triphosphate ([35S]GTPgammaS) binding in brain slices from Sprague-Dawley rats.

Journal: The Journal of pharmacology and experimental therapeutics 20050301

Title: Multiple transport systems mediate the hepatic uptake and biliary excretion of the metabolically stable opioid peptide [D-penicillamine2,5]enkephalin.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050201

Title: Melatonin exerts its analgesic actions not by binding to opioid receptor subtypes but by increasing the release of beta-endorphin an endogenous opioid.

Journal: Brain research bulletin 20050130

Title: The non-peptidic delta opioid receptor agonist TAN-67 enhances dopamine efflux in the nucleus accumbens of freely moving rats via a mechanism that involves both glutamate and free radicals.

Journal: Neuroscience 20050101

Title: [Activation of delta-opioid receptors increases resistance of isolated heart to ischemia/reperfusion: role of cAMP and intracellular calcium].

Journal: Izvestiia Akademii nauk. Seriia biologicheskaia 20050101

Title: Opioid receptor stimulation does not affect cellular hypoxia-induced gene responses mediated by hypoxia-inducible factor 1 in cultured cell lines.

Journal: Journal of anesthesia 20050101

Title: Interactions among mu- and delta-opioid receptors, especially putative delta1- and delta2-opioid receptors, promote dopamine release in the nucleus accumbens.

Journal: Neuroscience 20050101

Title: [The effect of stimulation of cardiac delta1-opioid receptors on the resistance of isolated heart to the action of ischemia and reperfusion].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20050101

Title: Displacement of opioid receptor binding ligands from the rat brain by N3-(2',5'-dimethoxyphenacyl) arabinofuranosyluracil.

Journal: Research communications in molecular pathology and pharmacology 20050101

Title: Medial preoptic area delta-opioid receptors inhibit lordosis.

Journal: Behavioural brain research 20041206

Title: [3H]DPDPE binding to delta opioid receptors in the rat mesocorticolimbic and nigrostriatal pathways is transiently increased by acute ethanol administration.

Journal: Brain research 20041203

Title: Hepatobiliary disposition of the metabolically stable opioid peptide [D-Pen2, D-Pen5]-enkephalin (DPDPE): pharmacokinetic consequences of the interplay between multiple transport systems.

Journal: The Journal of pharmacology and experimental therapeutics 20041201

Title: Activation of PLC-delta1 by Gi/o-coupled receptor agonists.

Journal: American journal of physiology. Cell physiology 20041201

Title: Modulation of voltage-dependent sodium channels by the delta-agonist SNC80 in acutely isolated rat hippocampal neurons.

Journal: Neuropharmacology 20041201

Title: The stimulatory effect of mu- and delta-opioid receptors on bovine pinealocyte melatonin synthesis.

Journal: Journal of pineal research 20041101

Title: Involvement of corticostriatal glutamatergic terminals in striatal dopamine release elicited by stimulation of delta-opioid receptors.

Journal: The European journal of neuroscience 20041101

Title: Delta-opioid receptor antagonists exhibit properties of partial delta-receptor agonists in isolated perfused heart.

Journal: Bulletin of experimental biology and medicine 20041001

Title: Opioid receptors in fast and slow skeletal muscles of normal and dystrophic mice.

Journal: Neuroscience letters 20040819

Title: The delta-opioid receptor participates in T-cell development by promoting negative selection.

Journal: Journal of neuroimmunology 20040801

Title: Feeding responses to mu-, delta- and kappa-opioid receptor agonists in the meat-type chick.

Journal: Pharmacology, biochemistry, and behavior 20040801

Title: P-glycoprotein expression, localization, and function in sandwich-cultured primary rat and human hepatocytes: relevance to the hepatobiliary disposition of a model opioid peptide.

Journal: Pharmaceutical research 20040701

Title: Activation of mu opioid receptors in the ventrolateral periaqueductal gray inhibits reflex micturition in anesthetized rats.

Journal: Neuroscience letters 20040610

Title: Chronic morphine-induced loss of the facilitative interaction between vasoactive intestinal polypeptide and delta-opioid: involvement of protein kinase C and phospholipase Cbetas.

Journal: Brain research 20040604

Title: Signal transducer and activator of transcription 3 activation by the delta-opioid receptor via Galpha14 involves multiple intermediates.

Journal: Molecular pharmacology 20040601

Title: A novel 3-step enantioselective synthesis of pyrenylalanine with subsequent incorporation into opioid, CCK, and melanotropin ligands.

Journal: Biochemical and biophysical research communications 20040528

Title: delta-Opioid receptor antagonists inhibit GIRK channel currents in acutely dissociated brainstem neurons of rat.

Journal: Brain research 20040501

Title: The delta agonists DPDPE and deltorphin II recruit predominantly mu receptors to produce thermal analgesia: a parallel study of mu, delta and combinatorial opioid receptor knockout mice.

Journal: The European journal of neuroscience 20040401

Title: Involvement of opioid receptor subtypes in both stimulatory and inhibitory effects of the opioid peptides on prolactin secretion during pregnancy.

Journal: Cellular and molecular neurobiology 20040401

Title: Opioid receptor stimulation suppresses the adrenal medulla hypoxic response in sheep by actions on Ca(2+) and K(+) channels.

Journal: The Journal of physiology 20040301

Title: DAMGO suppresses both excitatory and inhibitory synaptic transmission in supraoptic neurones of mouse hypothalamic slice preparations.

Journal: Journal of neuroendocrinology 20040301

Title: Mutation S363A in the human delta-opioid receptor selectively reduces down-regulation by a peptide agonist.

Journal: European journal of pharmacology 20040206

Title: Morphine prevents glutamate-induced death of primary rat neonatal astrocytes through modulation of intracellular redox.

Journal: Immunopharmacology and immunotoxicology 20040201

Title: The influence of opioid peptides on steroidogenesis in porcine granulosa cells.

Journal: Reproduction in domestic animals = Zuchthygiene 20040201

Title: Characterization of specific opioid binding sites in neural membranes from the myenteric plexus of porcine small intestine.

Journal: The Journal of pharmacology and experimental therapeutics 20040101

Title: [The role of delta-1 opiate receptors in regulation of contractility in isolated rat heart during normal oxygenation and ischemia-reperfusion].

Journal: Izvestiia Akademii nauk. Seriia biologicheskaia 20040101

Title: [Antiarrhythmic and cardioprotective effect of stimulation of delta1-opiate receptors in myocardial ischemia and reperfusion].

Journal: Patologicheskaia fiziologiia i eksperimental'naia terapiia 20040101

Title: Enkephalinergic inhibition of raphe pallidus inputs to rat hypoglossal motoneurones in vitro.

Journal: Neuroscience 20040101

Title: Action of kappa and Delta opioid agonists on premotor cardiac vagal neurons in the nucleus ambiguus.

Journal: Neuroscience 20040101

Title: DPI-3290 [(+)-3-((alpha-R)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N-(3-fluorophenyl)-N-methylbenzamide]. I. A mixed opioid agonist with potent antinociceptive activity.

Journal: The Journal of pharmacology and experimental therapeutics 20031201

Title: Lack of mu-opioid receptor-mediated G-protein activation in the spinal cord of mice lacking Exon 1 or Exons 2 and 3 of the MOR-1 gene.

Journal: Journal of pharmacological sciences 20031201

Title: Effects of endogenous and synthetic opioid peptides on neutrophil function in vitro.

Journal: British journal of anaesthesia 20031001

Title: Pharmacological characterization of a 7-benzylidenenaltrexone-preferring opioid receptor in porcine ileal submucosa.

Journal: British journal of pharmacology 20031001

Title: The regulation of steroidogenesis by opioid peptides in porcine theca cells.

Journal: Animal reproduction science 20030915

Title: Activation of peripheral delta opioid receptors eliminates cardiac electrical instability in a rat model of post-infarction cardiosclerosis via mitochondrial ATP-dependent K+ channels.

Journal: Life sciences 20030704

Title: Studies of micro-, kappa-, and delta-opioid receptor density and G protein activation in the cortex and thalamus of monkeys.

Journal: The Journal of pharmacology and experimental therapeutics 20030701

Title: DPDPE-UK14,304 synergy is retained in mu opioid receptor knockout mice.

Journal: Pain 20030701

Title: Contribution of organic anion transporting polypeptide OATP-C to hepatic elimination of the opioid pentapeptide analogue [D-Ala2, D-Leu5]-enkephalin.

Journal: The Journal of pharmacy and pharmacology 20030701

Title: Differential sorting of human delta-opioid receptors after internalization by peptide and alkaloid agonists.

Journal: The Journal of biological chemistry 20030620

Title: Effect of peptide conformation on membrane permeability.

Journal: The journal of peptide research : official journal of the American Peptide Society 20030601

Title: Selective delta-opioid receptor antagonist N,N(CH3)2-Dmt-Tic-OH does not reduce ethanol intake in alcohol-preferring AA rats.

Journal: Addiction biology 20030601

Title: [Effect of G protein in the dual regulation of opioid receptor agonist on the delayed rectified potassium channels].

Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20030601

Title: Opioid activity of C8813, a novel and potent opioid analgesic.

Journal: Life sciences 20030530

Title: Cardiac enkephalins interrupt vagal bradycardia via delta 2-opioid receptors in sinoatrial node.

Journal: American journal of physiology. Heart and circulatory physiology 20030501

Title: Kinin-induced anion-dependent secretion in porcine ileum: characterization and involvement of opioid- and cannabinoid-sensitive enteric neural circuits.

Journal: The Journal of pharmacology and experimental therapeutics 20030501

Title: Identity of the putative delta1-opioid receptor as a delta-kappa heteromer in the mouse spinal cord.

Journal: European journal of pharmacology 20030425

Title: [Dual regulation by delta opioid receptor agonists on the delayed rectified potassium channels in NG108-15 cells].

Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20030401

Title: Analgesia induced by local plantar injections of opiates in the formalin test in infant rats.

Journal: Developmental psychobiology 20030301

Title: Naloxone and its quaternary derivative, naloxone methiodide, have differing affinities for mu, delta, and kappa opioid receptors in mouse brain homogenates.

Journal: Brain research 20030227

Title: Systemic and spinal analgesic activity of a delta-opioid-selective lanthionine enkephalin analog.

Journal: The Journal of pharmacology and experimental therapeutics 20030201

Title: Simulation of the bis-(penicillamine) enkephalin in ammonium chloride solution: a comparison with sodium chloride.

Journal: Biopolymers 20030201

Title: Rac and Cdc42-dependent regulation of c-Jun N-terminal kinases by the delta-opioid receptor.

Journal: Journal of neurochemistry 20030201

Title: Effects of chronic intrathecal infusion of a partial differential opioid agonist in dogs.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030201

Title: Agonist-specific down-regulation of the human delta-opioid receptor.

Journal: European journal of pharmacology 20030110

Title: Facilitative interactions between vasoactive intestinal polypeptide and receptor type-selective opioids: implications for sensory afferent regulation of spinal opioid action.

Journal: Brain research 20030103

Title: Coexpression of delta-opioid receptors with micro receptors in GH3 cells changes the functional response to micro agonists from inhibitory to excitatory.

Journal: Molecular pharmacology 20030101

Title: Opioid receptor-induced GTPgamma35S binding during mouse development.

Journal: Developmental biology 20030101

Title: Spinal nitric oxide contributes to the analgesic effect of intrathecal [d-pen2,d-pen5]-enkephalin in normal and diabetic rats.

Journal: Anesthesiology 20030101

Title: Effects of imipramine treatment on delta-opioid receptors of the rat brain cortex and striatum.

Journal: Arzneimittel-Forschung 20030101

Title: Presynaptic delta opioid receptors differentially modulate rhythm and pattern generation in the ventral respiratory group of the rat.

Journal: Neuroscience 20030101

Title: [Significance of delta1-opioid receptors for regulation of the isolated heart resistance to ischemia-reperfusion].

Journal: Kardiologiia 20030101

Title: [The role of opiate receptors and ATP-dependent potassium channels of mitochondria in the formation of myocardial adaptive resistance to the arrhythmogenic effect of ischemia and reperfusion].

Journal: Izvestiia Akademii nauk. Seriia biologicheskaia 20030101

Title: Role of spinal nitric oxide in the inhibitory effect of [D-Pen2, D-Pen5]-enkephalin on ascending dorsal horn neurons in normal and diabetic rats.

Journal: The Journal of pharmacology and experimental therapeutics 20021201

Title: Opioid receptor subtypes differentially modulate serotonin efflux in the rat central nervous system.

Journal: The Journal of pharmacology and experimental therapeutics 20021101

Title: Comparison of receptor mechanisms and efficacy requirements for delta-agonist-induced convulsive activity and antinociception in mice.

Journal: The Journal of pharmacology and experimental therapeutics 20021101

Title: Pluronic p85 block copolymer enhances opioid peptide analgesia.

Journal: The Journal of pharmacology and experimental therapeutics 20021101

Title: Activation of delta-opioid receptors excites spinally projecting locus coeruleus neurons through inhibition of GABAergic inputs.

Journal: Journal of neurophysiology 20021101

Title: The role of delta-opioid receptors in estrogen facilitation of lordosis behavior.

Journal: Behavioural brain research 20021017

Title: Effect of in vivo and in vitro stimulation of delta1-opioid receptors on myocardial resistance to arrhythmogenic action of ischemia and reperfusion.

Journal: Bulletin of experimental biology and medicine 20021001

Title: Chronic agonist treatment converts antagonists into inverse agonists at delta-opioid receptors.

Journal: The Journal of pharmacology and experimental therapeutics 20020901

Title: The alpha9/alpha10-containing nicotinic ACh receptor is directly modulated by opioid peptides, endomorphin-1, and dynorphin B, proposed efferent cotransmitters in the inner ear.

Journal: Molecular and cellular neurosciences 20020801

Title: Inhibitory effects of opioids on voltage-dependent Ca(2+) channels and catecholamine secretion in cultured porcine adrenal chromaffin cells.

Journal: Brain research 20020628

Title: Role of delta-opioid receptor agonists on infarct size reduction in swine.

Journal: American journal of physiology. Heart and circulatory physiology 20020601

Title: Rapid quantification of the delta-opioid receptor selective enkephalin DPDPE in canine cerebrospinal fluid by liquid chromatography--mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020525

Title: Differential effects of chronic antidepressant treatments on micro- and delta-opioid receptors in rat brain.

Journal: European journal of pharmacology 20020517

Title: mu-Opioid receptors desensitize less rapidly than delta-opioid receptors due to less efficient activation of arrestin.

Journal: The Journal of biological chemistry 20020503

Title: N1'-fluoroethyl-naltrindole (BU97001) and N1'-fluoroethyl-(14-formylamino)-naltrindole (BU97018) potential delta-opioid receptor PET ligands.

Journal: Nuclear medicine and biology 20020501

Title: [Contribution of delta1-opioid receptors in regulation of cardiac resistance to ischemia-reperfusion].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20020501

Title: Possible involvement of mu1-opioid receptors in the fentanyl- or morphine-induced antinociception at supraspinal and spinal sites.

Journal: Life sciences 20020405

Title: Characterization of mu, kappa, and delta opioid binding in amphibian whole brain tissue homogenates.

Journal: The Journal of pharmacology and experimental therapeutics 20020401

Title: Deletion of CCK2 receptor in mice results in an upregulation of the endogenous opioid system.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020301

Title: mu/delta Cooperativity and opposing kappa-opioid effects in nucleus accumbens-mediated antinociception in the rat.

Journal: The European journal of neuroscience 20020301

Title: Transport and metabolism of opioid peptides across BeWo cells, an in vitro model of the placental barrier.

Journal: International journal of pharmaceutics 20020221

Title: Opioid agonists inhibit excitatory neurotransmission in ganglia and at the neuromuscular junction in Guinea pig gallbladder.

Journal: Gastroenterology 20020201

Title: [The postburn change in hypothalamic paraventricular beta-endorphin and the roles of delta-receptor in scalded rats].

Journal: Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20020201

Title: Interaction of enkephalin peptides with anionic model membranes.

Journal: Biochimica et biophysica acta 20020102

Title: Morphine tolerance in spinal cord is due to interaction between mu- and delta-receptors.

Journal: The Journal of pharmacology and experimental therapeutics 20020101

Title: Neuroanatomical localization of receptor-activated G proteins in brain.

Journal: Methods in enzymology 20020101

Title: Activation of mu-opioid receptors in rat ventrolateral medulla selectively blocks baroreceptor reflexes while activation of delta opioid receptors blocks somato-sympathetic reflexes.

Journal: Neuroscience 20020101

Title: Mu and Delta opioid receptors activate the same G proteins in human neuroblastoma SH-SY5Y cells.

Journal: British journal of pharmacology 20020101

Title: Endogenous morphine modulates acute thermonociception in mice.

Journal: Journal of neurochemistry 20020101

Title: [Stimulation of delta1-opioid receptors increases the ventricular fibrillation threshold in post-infarct cardiosclerosis: the role of K(ATP)-channels].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20020101

Title: Implications of phosphoinositide 3-kinase in the mu- and delta-opioid receptor-mediated supraspinal antinociception in the mouse.

Journal: Neuroscience 20020101

Title: Expression of calcitonin gene-related peptide, substance P and protein kinase C in cultured dorsal root ganglion neurons following chronic exposure to mu, delta and kappa opiates.

Journal: Neuroscience 20020101

Title: The bovine pineal gland contains delta and mu but not kappa or ORL1 opioid receptor subtypes.

Journal: Proceedings of the Western Pharmacology Society 20020101

Title: Activation profiles of opioid ligands in HEK cells expressing delta opioid receptors.

Journal: BMC neuroscience 20020101

Title: Up-regulation of RGS4 mRNA by opioid receptor agonists in PC12 cells expressing cloned mu- or kappa-opioid receptors.

Journal: European journal of pharmacology 20011214

Title: Delta opioid receptors mediate glucose uptake in skeletal muscles of lean and obese-diabetic (ob/ob) mice.

Journal: Metabolism: clinical and experimental 20011201

Title: [Role of delta opioid receptors and their ligands in the development of adaptive heart protection against arrhythmogenesis].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20011201

Title: Desensitization of endogenously expressed delta-opioid receptors: no evidence for involvement of G protein-coupled receptor kinase 2.

Journal: European journal of pharmacology 20011116

Title: Differential effects of morphine, DPDPE, and U-50488 on apomorphine-induced climbing behavior in mu-opioid receptor knockout mice.

Journal: Brain research. Molecular brain research 20011019

Title: Attenuation of G protein-mediated inhibition of N-type calcium currents by expression of caveolins in mammalian NG108-15 cells.

Journal: The Journal of physiology 20011015

Title: Potentiation of opioid analgesia in dopamine2 receptor knock-out mice: evidence for a tonically active anti-opioid system.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20011001

Title: Antisense oligodeoxynucleotides to mu- and delta-opioid receptor mRNA block the enhanced effects of opioids during intestinal inflammation.

Journal: European journal of pharmacology 20010928

Title: Resensitization of blood pressure response to mu-opioid peptide agonists after acute desensitization.

Journal: Anesthesia and analgesia 20010901

Title: Opioids confer myocardial tolerance to ischemia: interaction of delta opioid agonists and antagonists.

Journal: The Journal of thoracic and cardiovascular surgery 20010901

Title: [Effects of opioids on Ca2+/calmodulin dependent protein kinase signal pathway in NG108-15 cells].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20010901

Title: Pharmacodynamic and pharmacokinetic characterization of poly(ethylene glycol) conjugation to met-enkephalin analog [D-Pen2, D-Pen5]-enkephalin (DPDPE).

Journal: The Journal of pharmacology and experimental therapeutics 20010801

Title: L-type and T-type calcium channel blockade potentiate the analgesic effects of morphine and selective mu opioid agonist, but not to selective delta and kappa agonist at the level of the spinal cord in mice.

Journal: Pain 20010701

Title: Agonist Activity of the delta-antagonists TIPP and TIPP-psi in cellular models expressing endogenous or transfected delta-opioid receptors.

Journal: The Journal of pharmacology and experimental therapeutics 20010701

Title: Role of opioid receptors in neurogenic dural vasodilation and sensitization of trigeminal neurones in anaesthetized rats.

Journal: British journal of pharmacology 20010701

Title: Supraspinal delta- and mu-opioid receptors mediate gastric mucosal protection in the rat.

Journal: The Journal of pharmacology and experimental therapeutics 20010601

Title: Inhibition of calcium channels by opioid- and adenosine-receptor agonists in neurons of the nucleus accumbens.

Journal: British journal of pharmacology 20010601

Title: Discrimination between peptide and non-peptide opioid agonists on the transcription of opioid receptors in two cell lines.

Journal: Life sciences 20010504

Title: Respiratory function in adult mice lacking the mu-opioid receptor: role of delta-receptors.

Journal: The European journal of neuroscience 20010501

Title: Stimulatory effects of centrally injected kappa-opioid receptor agonists on gastric acid secretion in urethane-anesthetized rats.

Journal: European journal of pharmacology 20010427

Title: Uptake and efflux of the peptidic delta-opioid receptor agonist.

Journal: Neuroscience letters 20010406

Title: Mutation W284L of the human delta opioid receptor reveals agonist specific receptor conformations for G protein activation.

Journal: Life sciences 20010406

Title: Interaction of co-expressed mu- and delta-opioid receptors in transfected rat pituitary GH(3) cells.

Journal: Molecular pharmacology 20010401

Title: Galpha(14) links a variety of G(i)- and G(s)-coupled receptors to the stimulation of phospholipase C.

Journal: British journal of pharmacology 20010401

Title: Activity of mu- and delta-opioid agonists in vas deferens from mice deficient in MOR gene.

Journal: British journal of pharmacology 20010401

Title: Direct autocrine inhibition and cAMP-dependent potentiation of single L-type Ca2+ channels in bovine chromaffin cells.

Journal: The Journal of physiology 20010401

Title: The metabolic evidence of synergistic interaction between DAMGO and DPDPE on undifferentiated SH-SY5Y cells.

Journal: Neuroreport 20010326

Title: The role of delta-opioid receptor subtypes in neuropathic pain.

Journal: European journal of pharmacology 20010309

Title: Transport of opioids from the brain to the periphery by P-glycoprotein: peripheral actions of central drugs.

Journal: Nature neuroscience 20010301

Title: Expression of functional mu-opioid receptors during T cell development.

Journal: Journal of neuroimmunology 20010301

Title: Coincident signalling between the Gi/Go-coupled delta-opioid receptor and the Gq-coupled m3 muscarinic receptor at the level of intracellular free calcium in SH-SY5Y cells.

Journal: Journal of neurochemistry 20010301

Title: Neutrophil neutral endopeptidase variation and its regulation by opioid peptides.

Journal: International immunopharmacology 20010301

Title: Ligand binding profiles of delta-opioid receptor in human cerebral cortex membranes: evidence of delta-opioid receptor heterogeneity.

Journal: Life sciences 20010223

Title: Heterologous activation of protein kinase C stimulates phosphorylation of delta-opioid receptor at serine 344, resulting in beta-arrestin- and clathrin-mediated receptor internalization.

Journal: The Journal of biological chemistry 20010216

Title: The metabolic evidence of synergistic effect between ohmefentanyl and [D-Pen2, D-Pen5] enkephalin on differentiated SH-SY5Y cells in humans.

Journal: Neuroscience letters 20010209

Title: Pharmacological effects of naltriben as a ligand for opioid mu and kappa receptors in rat cerebral cortex.

Journal: Life sciences 20010202

Title: Interference of biocytin with opioid-evoked hyperpolarization and membrane properties of rat spinal substantia gelatinosa neurons.

Journal: Neuroscience letters 20010112

Title: Oligomerization of opioid receptors with beta 2-adrenergic receptors: a role in trafficking and mitogen-activated protein kinase activation.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20010102

Title: delta-opioid receptors inhibit neurogenic intestinal secretion evoked by mast cell degranulation and type I hypersensitivity.

Journal: Journal of neuroimmunology 20010101

Title: Antianalgesic action of nociceptin originating in the brain is mediated by spinal prostaglandin E(2) in mice.

Journal: The Journal of pharmacology and experimental therapeutics 20010101

Title: Cyclic AMP regulates the calcium transients released from IP(3)-sensitive stores by activation of rat kappa-opioid receptors expressed in CHO cells.

Journal: Cell calcium 20010101

Title: Simulations of the bis-penicillamine enkephalin in sodium chloride solution: a parameter study.

Journal: Biopolymers 20010101

Title: Activation of central opioid receptors may induce gastric mucosal defence in the rat.

Journal: Journal of physiology, Paris 20010101

Title: Alteration of early T cell development by opioid and superantigen stimulation.

Journal: Advances in experimental medicine and biology 20010101

Title: Crosstalk between chemokine and opioid receptors results in downmodulation of cell migration.

Journal: Advances in experimental medicine and biology 20010101

Title: [Stimulation of peripheral delta1-opioid receptors as a method of preventing ischemic and reperfusion arrhythmia: role of K(ATP)-channels].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20010101

Title: 5'-Guanidinonaltrindole, a highly selective and potent kappa-opioid receptor antagonist.

Journal: European journal of pharmacology 20000512

Title: Pharmacological delta1- and delta2-opioid receptor subtypes in the human neuroblastoma cell line SK-N-BE: no evidence for distinct molecular entities.

Journal: Biochemical pharmacology 20000415

Title: Differential G-protein activation by alkaloid and peptide opioid agonists in the human neuroblastoma cell line SK-N-BE.

Journal: The Biochemical journal 19990815

Title: G-protein-coupled receptor heterodimerization modulates receptor function.

Journal: Nature 19990617

Title: Mu- and delta-opioid receptor agonists inhibit DARPP-32 phosphorylation in distinct populations of striatal projection neurons.

Journal: The European journal of neuroscience 19990601

Title: Transport of opioid peptides into the central nervous system.

Journal: Journal of pharmaceutical sciences 19981101

Title: Delta opioid receptor enhancement of mu opioid receptor-induced antinociception in spinal cord.

Journal: The Journal of pharmacology and experimental therapeutics 19980601

Title: Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.

Journal: NIDA research monograph 19980301

Title: Differential effects of intrathecally administered delta and mu opioid receptor agonists on formalin-evoked nociception and on the expression of Fos-like immunoreactivity in the spinal cord of the rat.

Journal: The Journal of pharmacology and experimental therapeutics 19980101

Title: Kappa1- and kappa2-opioid receptors mediating presynaptic inhibition of dopamine and acetylcholine release in rat neostriatum.

Journal: British journal of pharmacology 19971001

Title: Sensitive analysis of [D-Pen2,5]enkephalin in rat serum by capillary electrophoresis and laser-induced fluorescence detection.

Journal: Journal of chromatography. B, Biomedical sciences and applications 19970912

Title: [D-Pen2,5]enkephalin and glutamate regulate the expression of delta-opioid receptors in rat cortical astrocytes.

Journal: Neuroscience letters 19970829

Title: Activation of the cloned human kappa opioid receptor by agonists enhances [35S]GTPgammaS binding to membranes: determination of potencies and efficacies of ligands.

Journal: The Journal of pharmacology and experimental therapeutics 19970801

Title: Relative efficacies of delta-opioid receptor agonists at the cloned human delta-opioid receptor.

Journal: European journal of pharmacology 19970512

Title: Opioid peptides: simultaneous delta agonism and mu antagonism in somatostatin analogues.

Journal: Peptides 19970101

Title: Extraordinary potency of a novel delta opioid receptor agonist is due in part to increased efficacy.

Journal: Life sciences 19970101

Title: Development of a model for the delta-opioid receptor pharmacophore: 3. Comparison of the cyclic tetrapeptide, Tyr-c[D-Cys-Phe-D-Pen]OH with other conformationally constrained delta-receptor selective ligands.

Journal: Biopolymers 19960201

Title: Role of opioid receptors in the spinal antinociceptive effects of neuropeptide FF analogues.

Journal: British journal of pharmacology 19960201

Title: Inhibition of adenylyl cyclase activity by the cholecystokinin analog SNF 9007 in neuroblastoma x glioma NG108-15 hybrid cells.

Journal: Regulatory peptides 19960116

Title: Differential desensitization of mu- and delta- opioid receptors in selected neural pathways following chronic morphine treatment.

Journal: British journal of pharmacology 19960101

Title: Serotonin and norepinephrine uptake inhibiting activity of centrally acting analgesics: structural determinants and role in antinociception.

Journal: The Journal of pharmacology and experimental therapeutics 19950901

Title: [D-Pen2,D-Pen5]enkephalin, a delta opioid agonist reduces endogenous aluminum content in the rat central nervous system.

Journal: Neuroscience 19950501

Title: Electrophysiological demonstration of mu, delta and kappa opioid receptors in the ventral pallidum.

Journal: The Journal of pharmacology and experimental therapeutics 19950301

Title: Opioid effects on spinal [3H]5-hydroxytryptamine release are not related to their antinociceptive action.

Journal: European journal of pharmacology 19950105

Title: Differential regulation of mu and delta opiate receptors by morphine, selective agonists and antagonists and differentiating agents in SH-SY5Y human neuroblastoma cells.

Journal: The Journal of pharmacology and experimental therapeutics 19940901

Title: Effect of ambient temperature on the ability of mu-, kappa- and delta-selective opioid agonists to modulate thermoregulatory mechanisms in the rat.

Journal: The Journal of pharmacology and experimental therapeutics 19940201

Title: Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.

Journal: Molecular pharmacology 19940201

Title: Cloning and pharmacological characterization of a rat kappa opioid receptor.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19931101

Title: Differential regulation of adenylyl cyclase activity by mu and delta opioids in rat caudate putamen and nucleus accumbens.

Journal: The Journal of pharmacology and experimental therapeutics 19931001

Title: Differential involvement of ventral tegmental mu, delta and kappa opioid receptors in modulation of basal mesolimbic dopamine release: in vivo microdialysis studies.

Journal: The Journal of pharmacology and experimental therapeutics 19930901

Title: In vitro potency, affinity and agonist efficacy of highly selective delta opioid receptor ligands.

Journal: The Journal of pharmacology and experimental therapeutics 19930801

Title: Go mediates the coupling of the mu opioid receptor to adenylyl cyclase in cloned neural cells and brain.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19930501

Title: Solution conformations of the peptide backbone for DPDPE and its beta-MePhe4-substituted analogs.

Journal: International journal of peptide and protein research 19930401

Title: In vivo modulation of gastrointestinal motor activity by Met-enkephalin, morphine and enkephalin analogs in chickens.

Journal: Regulatory peptides 19930305

Title: Modulation of peristalsis in the guinea-pig isolated small intestine by exogenous and endogenous opioids.

Journal: British journal of pharmacology 19920801

Title: Binding to opioid receptors of enkephalin derivatives taking alpha-helical conformation and its dimer.

Journal: International journal of peptide and protein research 19911001

Title: Comparative conformational analysis of [D-Pen2,D-Pen5]enkephalin (DPDPE): a molecular mechanics study.

Journal: Journal of computer-aided molecular design 19910801

Title: Kappa- and delta-opioids block sympathetically dependent hyperalgesia.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 19910401

Title: Influence of peptidase inhibitors on the apparent agonist potency of delta selective opioid peptides in vitro.

Journal: Life sciences 19910101

Title: The effects of opioid peptides on dopamine release in the nucleus accumbens: an in vivo microdialysis study.

Journal: Journal of neurochemistry 19901101

Title: Single residue modifications of the delta opioid receptor selective peptide, [D-Pen2,D-Pen5]-enkephalin (DPDPE). Correlation of pharmacological effects with structural and conformational features.

Journal: International journal of peptide and protein research 19900801

Title: Laminar distributions of muscarinic acetylcholine, serotonin, GABA and opioid receptors in human posterior cingulate cortex.

Journal: Neuroscience 19900101

Title: Guanine nucleotide regulation of [125I]beta-endorphin binding to NG108-15 and SK-N-SH cell membranes: specific cation requirements.

Journal: Brain research 19890724

Title: Dermenkephalin (Tyr-D-Met-Phe-His-Leu-Met-Asp-NH2): a potent and fully specific agonist for the delta opioid receptor.

Journal: Molecular pharmacology 19890601

Title: Novel peptidic mu opioid antagonists: pharmacologic characterization in vitro and in vivo.

Journal: The Journal of pharmacology and experimental therapeutics 19890501

Title: Antidiarrheal properties of supraspinal mu and delta and peripheral mu, delta and kappa opioid receptors: inhibition of diarrhea without constipation.

Journal: The Journal of pharmacology and experimental therapeutics 19890401

Title: Peripheral opioid receptors mediating antinociception in inflammation. Evidence for involvement of mu, delta and kappa receptors.

Journal: The Journal of pharmacology and experimental therapeutics 19890301

Title: Mu and delta opioid receptors inhibit serotonin release in rat hippocampus.

Journal: The Journal of pharmacology and experimental therapeutics 19890101

Title: Involvement of the mu-opiate receptor in peripheral analgesia.

Journal: Neuroscience 19890101

Title: Opioid receptor selectivity of beta-endorphin in vitro and in vivo: mu, delta and epsilon receptors.

Journal: The Journal of pharmacology and experimental therapeutics 19880901

Title: Inhibition of exocrine pancreatic secretion by opiates is mediated by suppression of cholinergic transmission: characterization of receptor subtypes.

Journal: The Journal of pharmacology and experimental therapeutics 19880701

Title: Comparative binding of mu and delta selective ligands in whole brain and pons/medulla homogenates from rat: affinity profiles of fentanyl derivatives.

Journal: Neuropharmacology 19880401

Title: [3H][D-Ser2(O-tert-butyl),Leu5]enkephalyl-Thr6 and [D-Ser2(O-tert-butyl),Leu5]enkephalyl-Thr6(O-tert-butyl). Two new enkephalin analogs with both a good selectivity and a high affinity toward delta-opioid binding sites.

Journal: The Journal of biological chemistry 19880325

Title: Affinity crosslinking of 125I-labeled human beta-endorphin to cell lines possessing either mu- or delta-type opioid binding sites.

Journal: Brain research 19880209

Title: Roles of central and peripheral mu, delta and kappa opioid receptors in the mediation of gastric acid secretory effects in the rat.

Journal: The Journal of pharmacology and experimental therapeutics 19880201

Title: Peptide opioid antagonist separates peripheral and central opioid antitransit effects.

Journal: The Journal of pharmacology and experimental therapeutics 19871101

Title: Mu and delta receptors belong to a family of receptors that are coupled to potassium channels.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19870801

Title: Opioid receptor regulation of the release of norepinephrine in brain.

Journal: Neuropharmacology 19870701

Title: Mu opioid antagonist properties of a cyclic somatostatin octapeptide in vivo: identification of mu receptor-related functions.

Journal: The Journal of pharmacology and experimental therapeutics 19870701

Title: Opioid receptor subtypes in the rat spinal cord: electrophysiological studies with mu- and delta-opioid receptor agonists in the control of nociception.

Journal: Brain research 19870609

Title: Morphine and enkephalins potently inhibit [3H]noradrenaline release from rat brain cortex synaptosomes: further evidence for a presynaptic localization of mu-opioid receptors.

Journal: Journal of neurochemistry 19870401

Title: Mu opioid receptor involvement in enkephalin activation of dopamine neurons in the ventral tegmental area.

Journal: The Journal of pharmacology and experimental therapeutics 19870401

Title: Effects of a novel opioid peptide antagonist on rat bladder motility in vivo.

Journal: Peptides 19870101

Title: Cyclic somatostatin octapeptide analogues with high affinity and selectivity toward mu opioid receptors.

Journal: Life sciences 19860616

Title: [3H]DSTBULET, a new linear hexapeptide with both an improved selectivity and a high affinity for delta-opioid receptors.

Journal: NIDA research monograph 19860101

Title: H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2: a potent and selective antagonist opioid receptors.

Journal: NIDA research monograph 19860101

Title: Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19831001

Title: F C Tortella, et al. Anticonvulsant Effects of Mu (DAGO) and Delta (DPDPE) Enkephalins in Rats. Peptides

Title: Yajima Y, et al. Effects of differential modulation of mu-, delta- and kappa-opioid systems on bicuculline-induced convulsions in the mouse. Brain Res. 2000 Apr 17;862(1-2):120-6.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:88373-73-3 Molecular Formula|88373-73-3 MDL|88373-73-3 SMILES|88373-73-3 DPDPE