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912758-00-0,MFCD11976903
Catalog No.:AA00GT7O

912758-00-0 | ATB-337

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$52.00   $36.00
- +
5mg
≥98%
in stock  
$222.00   $155.00
- +
10mg
≥98%
in stock  
$392.00   $274.00
- +
50mg
≥98%
in stock  
$1,699.00   $1,189.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00GT7O
Chemical Name:
ATB-337
CAS Number:
912758-00-0
Molecular Formula:
C23H15Cl2NO2S3
Molecular Weight:
504.4717
MDL Number:
MFCD11976903
SMILES:
O=C(Cc1ccccc1Nc1c(Cl)cccc1Cl)Oc1ccc(cc1)c1ssc(=S)c1
Properties
Computed Properties
 
Complexity:
674  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  
XLogP3:
6.9  

Literature

Title: Hydrogen sulphide-releasing diclofenac derivatives inhibit breast cancer-induced osteoclastogenesis in vitro and prevent osteolysis ex vivo.

Journal: British journal of pharmacology 20120301

Title: S-diclofenac protects against doxorubicin-induced cardiomyopathy in mice via ameliorating cardiac gap junction remodeling.

Journal: PloS one 20110101

Title: Novel dithiolethione-modified nonsteroidal anti-inflammatory drugs in human hepatoma HepG2 and colon LS180 cells.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090315

Title: Effect of S-diclofenac, a novel hydrogen sulfide releasing derivative inhibit rat vascular smooth muscle cell proliferation.

Journal: European journal of pharmacology 20081010

Title: The hydrogen sulphide-releasing derivative of diclofenac protects against ischaemia-reperfusion injury in the isolated rabbit heart.

Journal: British journal of pharmacology 20080101

Title: Effect of S-diclofenac, a novel hydrogen sulfide releasing derivative, on carrageenan-induced hindpaw oedema formation in the rat.

Journal: European journal of pharmacology 20070813

Title: Anti-inflammatory and gastrointestinal effects of a novel diclofenac derivative.

Journal: Free radical biology & medicine 20070301

Title: Gastrointestinal safety and anti-inflammatory effects of a hydrogen sulfide-releasing diclofenac derivative in the rat.

Journal: Gastroenterology 20070101

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SDS
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Tags:912758-00-0 Molecular Formula|912758-00-0 MDL|912758-00-0 SMILES|912758-00-0 ATB-337