Name: Name:AZ 628
Brand: AABLOCKS
SKU: AA00GTYC
Rating: 90 (10 reviews)

Catalog No.: AA00GTYC

878739-06-1 | AZ 628

Pack Size： 1mg

Purity： ≥98%

in stock

$46.00 $32.00

Pack Size： 5mg

Purity： 99%(HPLC)

in stock

$86.00 $60.00

Pack Size： 10mg

Purity： 99%(HPLC)

in stock

$154.00 $108.00

Pack Size： 25mg

Purity： 99%(HPLC)

in stock

$308.00 $216.00

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Technical Information

Catalog Number: AA00GTYC

Chemical Name: AZ 628

CAS Number: 878739-06-1

Molecular Formula: C27H25N5O2

Molecular Weight: 451.5197

MDL Number: MFCD17392577

SMILES: N#CC(c1cccc(c1)C(=O)Nc1ccc(c(c1)Nc1ccc2c(c1)c(=O)n(cn2)C)C)(C)C

Properties

Complexity: 845

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 34

Hydrogen Bond Acceptor Count: 5

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 5

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 4.2

Literature fold

Title: Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase.

Journal: Bioorganic & medicinal chemistry letters20140415

Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.

Journal: Bioorganic & medicinal chemistry letters20130801

Title: Selective Raf inhibition in cancer therapy.

Journal: Expert opinion on therapeutic targets20071201

Title: Khazak V, et al. Selective Raf inhibition in cancer therapy. Expert Opin Ther Targets. 2007 Dec;11(12):1587-609.

Title: Lau KS, et al. BAY61-3606 affects the viability of colon cancer cells in a genotype-directed manner. PLoS One. 2012;7(7):e41343.

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