Home Other Building Blocks 890087-21-5
890087-21-5,MFCD25541739
Catalog No.:AA00GU19

890087-21-5 | LUF 6000

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$218.00   $152.00
- +
5mg
≥98%
in stock  
$1,016.00   $711.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00GU19
Chemical Name:
LUF 6000
CAS Number:
890087-21-5
Molecular Formula:
C22H20Cl2N4
Molecular Weight:
411.3270
MDL Number:
MFCD25541739
SMILES:
Clc1ccc(cc1Cl)Nc1nc2ccccc2c2c1[nH]c(n2)C1CCCCC1
Properties
Computed Properties
 
Complexity:
529  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
7.1  

Literature

Title: Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications.

Journal: Journal of medicinal chemistry 20120628

Title: Novel 2- and 4-substituted 1H-imidazo[4,5-c]quinolin-4-amine derivatives as allosteric modulators of the A3 adenosine receptor.

Journal: Journal of medicinal chemistry 20090409

Title: A series of 2,4-disubstituted quinolines as a new class of allosteric enhancers of the adenosine A3 receptor.

Journal: Journal of medicinal chemistry 20090226

Title: Flexible modulation of agonist efficacy at the human A3 adenosine receptor by the imidazoquinoline allosteric enhancer LUF6000.

Journal: BMC pharmacology 20080101

Title: Structure-activity relationships of new 1H-imidazo[4,5-c]quinolin-4-amine derivatives as allosteric enhancers of the A3 adenosine receptor.

Journal: Journal of medicinal chemistry 20060601

Title: Du L, et al. Species differences and mechanism of action of A3 adenosine receptor allosteric modulators. Purinergic Signal. 2018;14(1):59-71.

Title: Cohen S, et al. A₃ adenosine receptor allosteric modulator induces an anti-inflammatory effect: in vivo studies and molecular mechanism of action. Mediators Inflamm. 2014;2014:708746.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 890087-21-5
Tags:890087-21-5 Molecular Formula|890087-21-5 MDL|890087-21-5 SMILES|890087-21-5 LUF 6000