Home Deuterated Building Blocks 894002-50-7
894002-50-7,MFCD05960679
Catalog No.:AA00GU5X

894002-50-7 | Ldn-212320

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5mg
≥95%
in stock  
$89.00   $62.00
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10mg
≥95%
in stock  
$156.00   $109.00
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25mg
in stock  
$315.00   $221.00
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50mg
in stock  
$492.00   $344.00
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100mg
in stock  
$804.00   $563.00
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500mg
in stock  
$2,453.00   $1,717.00
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1000mg
in stock  
$3,886.00   $2,720.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00GU5X
Chemical Name:
Ldn-212320
CAS Number:
894002-50-7
Molecular Formula:
C17H15N3S
Molecular Weight:
293.3861
MDL Number:
MFCD05960679
SMILES:
Cc1ccccc1CSc1ccc(nn1)c1ccccn1
Properties
Computed Properties
 
Complexity:
312  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
4  
XLogP3:
3.2  

Downstream Synthesis Route

[1]Xing,Xuechao;Chang,Ling-Chu;Kong,Qiongman;Colton,CraigK.;Lai,Liching;Glicksman,MarcieA.;Lin,Chien-LiangGlenn;Cuny,GregoryD.[BioorganicandMedicinalChemistryLetters,2011,vol.21,#19,p.5774-5777]

[1]Locationinpatent:schemeortableXing,Xuechao;Chang,Ling-Chu;Kong,Qiongman;Colton,CraigK.;Lai,Liching;Glicksman,MarcieA.;Lin,Chien-LiangGlenn;Cuny,GregoryD.[BioorganicandMedicinalChemistryLetters,2011,vol.21,#19,p.5774-5777]

[1]Locationinpatent:schemeortableXing,Xuechao;Chang,Ling-Chu;Kong,Qiongman;Colton,CraigK.;Lai,Liching;Glicksman,MarcieA.;Lin,Chien-LiangGlenn;Cuny,GregoryD.[BioorganicandMedicinalChemistryLetters,2011,vol.21,#19,p.5774-5777]

[1]Xing,Xuechao;Chang,Ling-Chu;Kong,Qiongman;Colton,CraigK.;Lai,Liching;Glicksman,MarcieA.;Lin,Chien-LiangGlenn;Cuny,GregoryD.[BioorganicandMedicinalChemistryLetters,2011,vol.21,#19,p.5774-5777]

[1]Xing,Xuechao;Chang,Ling-Chu;Kong,Qiongman;Colton,CraigK.;Lai,Liching;Glicksman,MarcieA.;Lin,Chien-LiangGlenn;Cuny,GregoryD.[BioorganicandMedicinalChemistryLetters,2011,vol.21,#19,p.5774-5777]

Literature

Title: Structure-activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators.

Journal: Bioorganic & medicinal chemistry letters 20111001

Title: Ghallab Alotaibi, et al. Effects of glial glutamate transporter activator in formalin-induced pain behaviour in mice. Eur J Pain. 2019 Apr;23(4):765-783.

Title: Xuechao Xing, et al. Structure-activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5774-7.

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SDS
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